Pharma company: bedford laboratories
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List of bedford laboratories products:
- Acetazolamide - DESCRIPTION Acetazolamide, an inhibitor of the enzyme carbonic anhydrase, is a white to faintly yellowish white crystalline, odorless powder, weakly acidic, very slightly soluble in water and slightly soluble in alcohol. The chemical name for acetazolamide is N -(5-Sulfamoyl-1,3,4-thiadiazol-2yl)-acetamide and has the following structural formula: Acetazolamide is available for...
- Acetylcysteine - 1 INDICATIONS AND USAGE CETYLEV is indicated to prevent or lessen hepatic injury after ingestion of a potentially hepatotoxic quantity of acetaminophen in patients with acute ingestion or from repeated supratherapeutic ingestion (RSI). CETYLEV is an antidote for acetaminophen overdose indicated to prevent or lessen hepatic injury after ingestion of a potentially hepatotoxic quantity of...
- Acyclovir - Pharmacological action Acyclovir Pharma is an antiviral agent. Thymidine kinase of virus-infected cells actively converts acyclovir through a series of sequential reactions in the mono-, di- and triphosphate of acyclovir. The latter interacts with the viral DNA polymerase, and embedded in DNA, which is synthesized for new viruses. Thus it is formed a "defective" viral DNA which leads to suppression of replication of new generations of viruses. This mediciine acyclovir is active against...
- Adenosine - Warnings and Precautions: Cardiac Arrest, Ventricular Arrhythmias, and Myocardial Infarction ( 5.1 ) 10/2013 ...
- Allopurinol - Pharmacological action Allopurinol Laboratories is a medication that violates the synthesis of uric acid. This drug is a structural analog of hypoxanthine. It inhibits the enzyme xanthine oxidase, which is involved in the conversion of hypoxanthine to xanthine and xanthine to uric acid. This is due to decrease in the concentration of uric acid and its salts in body fluids and urine, which helps dissolve existing uric acid deposits and prevents their formation in tissues and kidney....
- Alprostadil - Pharmacological action Alprostadil is the medication of prostaglandin E1. This drug improves microcirculation and peripheral circulation, it has angioprotective action. With systemic administration causes relaxation of smooth muscle fibers, exerts vasodilating effect, reduces PR, lowers blood pressure. It is noted a reflex increase in cardiac output and heart rate. Improves the rheological properties of blood helping to increase the elasticity of red blood cells and reducing platelet...
- Amikacin - Amikacin is a semi-synthetic aminoglycoside antibiotic derived from kanamycin A. Similar to other aminoglycosides, amikacin disrupts bacterial protein synthesis by binding to the 30S ribosome of susceptible organisms. Binding interferes with mRNA binding and tRNA acceptor sites leading to the production of non-functional or toxic peptides. Other mechanisms not fully understood may confer the bactericidal effects of amikacin. Amikacin is also nephrotoxic and ototoxic. Indication: For short-term...
- Amiodarone - An antianginal and antiarrhythmic drug. It increases the duration of ventricular and atrial muscle action by inhibiting Na,K-activated myocardial adenosine triphosphatase. There is a resulting decrease in heart rate and in vascular resistance. [PubChem] Indication: Intravenously, for initiation of treatment and prophylaxis of frequently recurring ventricular fibrillation and hemodynamically unstable ventricular tachycardia in patients refractory to other therapy. Orally, for the treatment of...
- Amrinone - Amrinone (or inamrinone) is a type 3 pyridine phosphodiesterase inhibitor. It is used in the treatment of congestive heart failure. Indication: Used in the treatment of congestive heart failure. Amrinone is a positive inotropic cardiotonic with vasodilator properties, phosphodiesterase inhibitory activity, and the ability to stimulate calcium ion influx into the cardiac cell.
- Atracurium - A non-depolarizing neuromuscular blocking agent with short duration of action. Its lack of significant cardiovascular effects and its lack of dependence on good kidney function for elimination provide clinical advantage over alternate non-depolarizing neuromuscular blocking agents. [PubChem] Indication: For use, as an adjunct to general anesthesia, to facilitate endotracheal intubation and to provide skeletal muscle relaxation during surgery or mechanical ventilation. Atracurium is a...
- Atracurium preservative free
- Azathioprine - SPL UNCLASSIFIED SECTION PRODUCT INFORMATION Rx only WARNING - MALIGNANCY Chronic immunosuppression with IMURAN, a purine antimetabolite increases risk of malignancy in humans. Reports of malignancy include post-transplant lymphoma and hepatosplenic T-cell lymphoma (HSTCL) in patients with inflammatory bowel disease....
- Aztreonam - To reduce the development of drug-resistant bacteria and maintain the effectiveness of CAYSTON and other antibacterial drugs, CAYSTON should be used only to treat patients with cystic fibrosis (CF) known to have Pseudomonas aeruginosa in the lungs. 1 INDICATIONS AND USAGE CAYSTON ® is indicated to improve respiratory symptoms in cystic fibrosis (CF) patients with Pseudomonas aeruginosa . ...
- Bumetanide - SPL UNCLASSIFIED SECTION Rx Only WARNING Bumetanide is a potent diuretic which, if given in excessive amounts, can lead to a profound diuresis with water and electrolyte depletion. Therefore, careful medical supervision is required, and dose and dosage...
- Buprenorphine - SPL UNCLASSIFIED SECTION SPL Unclassified section and Caution Simbadol ™ (buprenorphine injection) 1.8 mg/mL For subcutaneous use in cats Opioid Analgesic CAUTION: Federal law restricts this drug to use by or on the order...
- Butorphanol - A synthetic morphinan analgesic with narcotic antagonist action. It is used in the management of severe pain. [PubChem] Indication: For the relief of moderate to severe pain. Butorphanol is a synthetic opioid agonist-antagonist analgesic with a pharmacological and therapeutic profile that has been well established since its launch as a parenteral formulation in 1978. The introduction of a transnasal formulation of butorphanol represents a new and noninvasive presentation of an analgesic for...
- Butorphanol preservative free
- Carboplatin - SPL UNCLASSIFIED SECTION Rx Only WARNING Carboplatin injection should be administered under the supervision of a qualified physician experienced in the use of cancer chemotherapeutic agents. Appropriate management of therapy and complications is possible only when adequate treatment facilities are readily available. ...
- Cefazolin - SPL UNCLASSIFIED SECTION To reduce the development of drug-resistant bacteria and maintain the effectiveness of Cefazolin for Injection and other antibacterial drugs, Cefazolin for Injection should be used only to treat or prevent infections that are proven or strongly suspected to be caused by bacteria. DESCRIPTION Cefazolin for Injection, USP is a semi-synthetic cephalosporin for parenteral...
- Ceftriaxone - SPL UNCLASSIFIED SECTION Rx only To reduce the development of drug-resistant bacteria and maintain the effectiveness of Ceftriaxone for Injection, USP and other antibacterial drugs, Ceftriaxone for Injection, USP should be used only to treat or prevent infections that are proven or strongly suspected to be caused by bacteria. DESCRIPTION ...
- Cerubidine - Daunorubicin belongs to the group of cancer-fighting medicines known as antineoplastics, and specifically to the family of antineoplastics called anthracyclines. Another anthracycline is doxorubicin. Daunorubicin is used alone or in combination with other antineoplastic medications for the treatment of many types of cancer including cancers of the blood (e.g., leukemia), lymphosarcoma, reticulosarcoma, Wilm's tumour, and Ewing tumours. Daunorubicin causes the death of cancer cells by...
- Chloroprocaine - Chloroprocaine hydrochloride is a local anesthetic given by injection during surgical procedures and labor and delivery. Chloroprocaine, like other local anesthetics, blocks the generation and the conduction of nerve impulses, presumably by increasing the threshold for electrical excitation in the nerve, by slowing the propagation of the nerve impulse and by reducing the rate of rise of the action potential. Indication: For the production of local anesthesia by infiltration and peripheral nerve...
- Ciprofloxacin - Chemical Structure WARNING Fluoroquinolones, including Ciprofloxacin Tablets, are associated with an increased risk of tendinitis and tendon rupture in all ages. This risk is further increased in older patients usually over 60 years of age, in patients taking corticosteroid drugs, and in patients with kidney, heart or lung transplants (See WARNINGS ). ...
- Ciprofloxacin in Dextrose 5% in plastic container - Pharmacological action Ciprofloxacin is a broad-spectrum antimicrobial drug of fluoroquinolone group with bactericidal action. Inhibits DNA gyrase and inhibits the synthesis of bacterial DNA. Highly active against most gram-negative bacteria: Pseudomonas aeruginosa, Haemophilus influenzae, Escherichia coli, Shigella spp., Salmonella spp., Neisseria meningitidis, Neisseria gonorrhoeae. Ciprofloxacin is active against Staphylococcus spp. (including strains producing and not producing...
- Cisplatin - SPL UNCLASSIFIED SECTION Rx only WARNING PLATINOL-AQ (cisplatin injection) should be administered under the supervision of a qualified physician experienced in the use of cancer chemotherapeutic agents. Appropriate management of therapy and complications is possible only when adequate diagnostic and treatment facilities are readily available. ...
- Cladribine - SPL UNCLASSIFIED SECTION For Intravenous Infusion Only Rx only WARNING: Cladribine injection should be administered under the supervision of a qualified physician experienced in the use of antineoplastic therapy. Suppression of bone marrow function should be anticipated. This is usually reversible and appears to be dose dependent...
- Clindamycin - ZydaClin™ (clindamycin) Oral Drops liquid For Use in Dogs & Cats Equivalent to 25 mg per mL clindamycin ...
- Cyclosporine - WARNING Only physicians experienced in management of systemic immunosuppressive therapy for the indicated disease should prescribe Neoral. At doses used in solid organ transplantation, only physicians experienced in immunosuppressive therapy and management of organ transplant recipients should prescribe Neoral. Patients receiving the drug should be managed in facilities equipped and staffed with...
- Cytarabine - SPL UNCLASSIFIED SECTION PHARMACY BULK PACKAGE - NOT FOR DIRECT INFUSION ...
- Dacarbazine - SPL UNCLASSIFIED SECTION Rx only Hospira logo WARNING ...
- Dactinomycin - Cosmegen Label WARNING COSMEGEN® (dactinomycin for injection) should be administered only under the supervision of a physician who is experienced in the use of cancer chemotherapeutic agents. This drug is HIGHLY TOXIC and both powder and solution must be handled and administered with care. Inhalation of dust or vapors and contact with skin or mucous membranes, especially those...
- Daunorubicin - A very toxic anthracycline aminoglycoside antineoplastic isolated from Streptomyces peucetius and others, used in treatment of leukemia and other neoplasms. [PubChem] Indication: For remission induction in acute nonlymphocytic leukemia (myelogenous, monocytic, erythroid) of adults and for remission induction in acute lymphocytic leukemia of children and adults. Daunorubicin is an antineoplastic in the anthracycline class. General properties of drugs in this class include: interaction with DNA...
- Deferoxamine - Natural product isolated from Streptomyces pilosus. It forms iron complexes and is used as a chelating agent, particularly in the mesylate form. [PubChem] Indication: Used to treat acute iron or aluminum toxicity (an excess of aluminum in the body) in certain patients. Also used in certain patients with anemia who must receive many blood transfusions. Deferoxamine, otherwise known as desferrioxamine or desferal, is a chelating agent used to remove excess iron or aluminum from the body. It acts...
- Desmopressin - Desmopressin is a chemical that is similar to Antidiuretic Hormone (ADH) which is found naturally in the body. It increases urine concentration and decreases urine production. Desmopressin is used to prevent and control excessive thirst, urination, and dehydration caused by injury, surgery, and certain medical conditions, allowing you to sleep through the night without awakening to urinate. It is also used to treat specific types of diabetes insipidus and conditions after head injury or...
- Desmopressin preservative free
- Dexrazoxane - 1 INDICATIONS AND USAGE ZINECARD is indicated for reducing the incidence and severity of cardiomyopathy associated with doxorubicin administration in women with metastatic breast cancer who have received a cumulative doxorubicin dose of 300 mg/m 2 and who will continue to receive doxorubicin therapy to maintain tumor control. Do not use with the initiation of doxorubicin therapy [see Warnings and Precautions (5.2) ] . ...
- Dicyclomine preservative free
- Dihydroergotamine - A 9,10alpha-dihydro derivative of ergotamine. It is used as a vasoconstrictor, specifically for the therapy of migraine disorders. [PubChem] Indication: For the acute treatment of migraine headaches with or without aura and the acute treatment of cluster headache episodes. Dihydroergotamine is indicated for the acute treatment of migraine headaches with or without aura and the acute treatment of cluster headache episodes. Dihydroergotamine binds with high affinity to 5-HT1Da and 5-HT1Db...
- Diltiazem - A benzothiazepine derivative with vasodilating action due to its antagonism of the actions of the calcium ion in membrane functions. It is also teratogenic. [PubChem] Indication: For the treatment of Hypertension Diltiazem, a benzothiazepine calcium-channel blocker, is used alone or with an angiotensin-converting enzyme inhibitor, to treat hypertension, chronic stable angina pectoris, and Prinzmetal's variant angina. Diltiazem is a non-dihydropyridine (DHP)member of the calcium channel blocker...
- Dipyridamole - DESCRIPTION PERSANTINE® (dipyridamole USP) is a platelet inhibitor chemically described as 2,2',2",2"'-[(4,8- Dipiperidinopyrimido[5,4- d ]pyrimidine-2,6-diyl)dinitrilo]-tetraethanol. It has the following structural formula: Dipyridamole is an odorless yellow crystalline powder, having a bitter taste. It is soluble in dilute acids, methanol and chloroform, and practically insoluble in water. PERSANTINE...
- Dobutamine - A beta-2 agonist catecholamine that has cardiac stimulant action without evoking vasoconstriction or tachycardia. It is proposed as a cardiotonic after myocardial infarction or open heart surgery. [PubChem] Indication: For inotropic support in the short- term treatment of patients with cardiac decompensation due to depressed contractility resulting either from organic heart disease or from cardiac surgical procedures Dobutamine is a direct-acting inotropic agent whose primary activity results...
- Doxapram - A central respiratory stimulant with a brief duration of action. (From Martindale, The Extra Pharmocopoeia, 30th ed, p1225) Indication: For use as a temporary measure in hospitalized patients with acute respiratory insufficiency superimposed on chronic obstructive pulmonary disease. Doxapram is an analeptic agent (a stimulant of the central nervous system). The respiratory stimulant action is manifested by an increase in tidal volume associated with a slight increase in respiratory rate. A...
- Doxorubicin - WARNING: CARDIOMYOPATHY, SECONDARY MALIGNANCIES, EXTRAVASATION AND TISSUE NECROSIS, and SEVERE MYELOSUPPRESSION Cardiomyopathy: Myocardial damage, including acute left ventricular failure can occur with doxorubicin HCl. The risk of cardiomyopathy is proportional to the cumulative exposure with incidence rates from 1% to 20% for cumulative doses ranging from 300 mg/m 2 to 500...
- Doxycycline - Pharmacological action Doxycycline is an semisynthetic tetracycline group's antibiotic of broad-spectrum. This medication has bacteriostatic action due to suppression of protein synthesis of pathogens. It active against aerobic gram-positive bacteria: Staphylococcus spp. (including strains producing penicillinase), Streptococcus spp. (including Streptococcus pneumoniae), Bacillus anthracis, Listeria monocytogenes; anaerobic bacteria: Clostridium spp. Doxycycline is also active against...
- Enalaprilat - Enalapril information Enalapril is one of the most effective anti-hypertensive drugs in the market. Belonging to the angiotensin-converting-enzyme inhibitors (ACE inhibitors) category of drugs, Enalapril helps to keep raising blood pressure under control thereby reducing the risk factors of this disease. Since hypertension works out the heart muscles to cause early arterial failure, Enalapril stands in the way and helps to keep your heart healthy, indirectly. Like all other ACE inhibitors,...
- Epirubicin - An anthracycline which is the 4'-epi-isomer of doxorubicin. The compound exerts its antitumor effects by interference with the synthesis and function of DNA. [PubChem] Indication: For use as a component of adjuvant therapy in patients with evidence of axillary node tumor involvement following resection of primary breast cancer. Epirubicin is an antineoplastic in the anthracycline class. General properties of drugs in this class include: interaction with DNA in a variety of different ways...
- Esmolol - Esmolol (trade name Brevibloc) is a cardioselective beta1 receptor blocker with rapid onset, a very short duration of action, and no significant intrinsic sympathomimetic or membrane stabilising activity at therapeutic dosages.Esmolol decreases the force and rate of heart contractions by blocking beta-adrenergic receptors of the sympathetic nervous system, which are found in the heart and other organs of the body. Esmolol prevents the action of two naturally occurring substances: epinephrine...
- Etomidate - SPL UNCLASSIFIED SECTION For intravenous use DESCRIPTION AMIDATE (Etomidate Injection, USP) is a sterile, nonpyrogenic solution. Each milliliter contains etomidate, 2 mg, propylene glycol 35% v/v. The pH is 6.0 (4.0 to 7.0). It is intended for the induction of general anesthesia by intravenous injection. The drug etomidate is chemically identified as...
- Etoposide - WARNINGS Etoposide should be administered under the supervision of a qualified physician experienced in the use of cancer chemotherapeutic agents. Severe myelosuppression with resulting infection or bleeding may occur. DESCRIPTION Etoposide (also commonly known as VP-16) is a semisynthetic derivative of...
- Famotidine - DESCRIPTION The active ingredient in PEPCID* Registered trademark of Merck Sharp and Dohme Corp, a subsidiary of Merck & Co. Inc. and is used under license. (famotidine) is a histamine H 2 ‑receptor antagonist. Famotidine is N -(aminosulfonyl)-3-[[[2-[(diaminomethylene)amino]-4-thiazolyl]methyl]thio]propanimidamide. The empirical formula of famotidine is C 8 H 15 N 7 O 2 S 3 and its molecular weight is 337.43. Its structural...
- Famotidine preservative free
- Fenoldopam - A dopamine D1 receptor agonist that is used as an antihypertensive agent. It lowers blood pressure through arteriolar vasodilation. [PubChem] Indication: For the in-hospital, short-term (up to 48 hours) management of severe hypertension when rapid, but quickly reversible, emergency reduction of blood pressure is clinically indicated, including malignant hypertension with deteriorating end-organ function. Fenoldopam is an agonist at D1-like dopamine receptors, binds to α2-adrenoceptors,...
- Floxuridine - SPL UNCLASSIFIED SECTION FOR INTRA-ARTERIAL INFUSION ONLY WARNING It is recommended that Floxuridine for Injection, USP be given only by or...
- Fluconazole in Sodium Chloride 0.9% - Pharmacological action Fluconazole is an antifungal drug from the group of triazole derivatives. Inhibits the synthesis of ergosterol disrupting the permeability of the cell wall. This medication is active against Candida, Microsporum, Cryptococcus neoformans, Trichophyton. Pharmacokinetics Fluconazole is well absorbed after oral administration. Simultaneous ingestion does not affect absorption. The bioavailability is 90%. Fluconazole is widely distributed in tissues and organs of the...
- Fluconazole in Sodium Chloride 0.9% in plastic container - Pharmacological action Fluconazole is an antifungal drug from the group of triazole derivatives. Inhibits the synthesis of ergosterol disrupting the permeability of the cell wall. This medication is active against Candida, Microsporum, Cryptococcus neoformans, Trichophyton. Pharmacokinetics Fluconazole is well absorbed after oral administration. Simultaneous ingestion does not affect absorption. The bioavailability is 90%. Fluconazole is widely distributed in tissues and organs of the...
- Flumazenil - DESCRIPTION Flumazenil injection is a benzodiazepine receptor antagonist. Chemically, flumazenil is ethyl 8-fluoro-5,6-dihydro-5-methyl-6-oxo-4H-imidazo[1,5-a](1,4) benzodiazepine-3-carboxylate. Flumazenil has an imidazobenzodiazepine structure, a calculated molecular weight of 303.3 and the following structural formula: C 15 H 14 FN 3 O 3 ...
- Fluorouracil - Dosage and Administration ( 2 ) 07/2016 1 INDICATIONS AND USAGE Adrucil (fluorouracil injection) is indicated for the treatment of patients with: Adrucil ® (fluorouracil injection) is a nucleoside metabolic inhibitor indicated for the treatment of...
- Fluphenazine - A phenothiazine used in the treatment of psychoses. Its properties and uses are generally similar to those of chlorpromazine. [PubChem] Indication: For management of manifestations of psychotic disorders. Fluphenazine is a trifluoro-methyl phenothiazine derivative intended for the management of schizophrenia and other psychotic disorders. Fluphenazine has not been shown effective in the management of behaviorial complications in patients with mental retardation.
- Fosphenytoin - Fosphenytoin is a water-soluble phenytoin prodrug used only in hospitals for the treatment of epileptic seizures. It works by slowing down impulses in the brain that cause seizures. Its main mechanism is to block frequency-dependent, use-dependent and voltage-dependent neuronal sodium channels, and therefore limit repetitive firing of action potentials. Indication: For the control of generalized convulsive status epilepticus and prevention and treatment of seizures occurring during neurosurgery...
- Ganciclovir - THE CLINICAL TOXICITY OF GANCICLOVIR INCLUDES GRANULOCYTOPENIA, ANEMIA AND THROMBOCYTOPENIA. IN ANIMAL STUDIES GANCICLOVIR WAS CARCINOGENIC, TERATOGENIC AND CAUSED ASPERMATOGENESIS. GANCICLOVIR CAPSULES ARE INDICATED ONLY FOR PREVENTION OF CMV DISEASE IN PATIENTS WITH ADVANCED HIV INFECTION AT RISK FOR CMV DISEASE, FOR MAINTENANCE TREATMENT OF CMV RETINITIS IN IMMUNOCOMPROMISED PATIENTS, AND...
- GlucaGen - Glucagon belongs to the group of medications called hyperglycemic agents. It is used to treat severe hypoglycemia (low blood sugar) when someone with insulin-treated diabetes is unable to give glucose to themselves (e.g., unconscious). Symptoms of severely low blood sugar include disorientation, unconsciousness, and seizures. This medication works in the liver to produce glucose (sugar) and increase blood sugar. It usually works within 10 to 15 minutes. If a person does not respond to...
- Granisetron - 1 INDICATIONS AND USAGE Sancuso ® (Granisetron Transdermal System) is indicated for the prevention of nausea and vomiting in patients receiving moderately and/or highly emetogenic chemotherapy regimens of up to 5 consecutive days duration. Sancuso is a serotonin -3 (5-HT3) receptor antagonist indicated for the prevention of nausea and vomiting in patients receiving moderately and/or highly...
- Ifosfamide - WARNING: MYELOSUPPRESSION, NEUROTOXICITY, and UROTOXICITY Myelosuppression can be severe and lead to fatal infections. Monitor blood counts prior to and at intervals after each treatment cycle. CNS toxicities can be severe and result in encephalopathy and death. Monitor for CNS toxicity and discontinue treatment for encephalopathy. Nephrotoxicity can be severe and result in renal failure. Hemorrhagic cystitis can be severe and can be reduced by the...
- Indomethacin - SPL UNCLASSIFIED SECTION Rx only ...
- Irinotecan - Irinotecan is an antineoplastic enzyme inhibitor primarily used in the treatment of colorectal cancer. It is a derivative of camptothecin that inhibits the action of topoisomerase I. Irinotecan prevents religation of the DNA strand by binding to topoisomerase I-DNA complex, and causes double-strand DNA breakage and cell death. Indication: For the treatment of metastatic colorectal cancer (first-line therapy when administered with 5-fluorouracil and leucovorin). Also used in combination with...
- Ketamine - A cyclohexanone derivative used for induction of anesthesia. Its mechanism of action is not well understood, but ketamine can block NMDA receptors (receptors, N-methyl-D-aspartate) and may interact with sigma receptors. [PubChem] Indication: For use as the sole anesthetic agent for diagnostic and surgical procedures that do not require skeletal muscle relaxation. Ketamine is a rapid-acting general anesthetic producing an anesthetic state characterized by profound analgesia, normal...
- Ketorolac - A pyrrolizine carboxylic acid derivative structurally related to indomethacin. It is an NSAID and is used principally for its analgesic activity. (From Martindale The Extra Pharmacopoeia, 31st ed) Indication: For the short-term (~5 days) management of moderately severe acute pain that requires analgesia at the opioid level, usually in a postoperative setting. Ketorolac, an antiinflammatory agent with analgesic and antipyretic properties, is used to treat osteoarthritis and control acute pain....
- Labetalol - Blocker of both alpha- and beta-adrenergic receptors that is used as an antihypertensive. [PubChem] Indication: For the management of hypertension (alone or in combination with other classes of antihypertensive agents), as well as chronic stable angina pectoris and sympathetic overactivity syndrome associated with severe tetanus. Labetalol is used parenterally for immediate reduction in blood pressure in severe hypertension or in hypertensive crises when considered an emergency, for the control...
- Leucovorin - The active metabolite of folic acid. Leucovorin is used principally as its calcium salt as an antidote to folic acid antagonists which block the conversion of folic acid to folinic acid. [PubChem] Indication: For the treatment of osteosarcoma (after high dose methotrexate therapy). Used to diminish the toxicity and counteract the effects of impaired methotrexate elimination and of inadvertent overdosages of folic acid antagonists, and to treat megaloblastic anemias due to folic acid deficiency....
- Leucovorin preservative free
- Leuprolide - Leuprolide is used to treat advanced prostate cancer in men. It is not a cure. Most types of prostate cancer need the male hormone testosterone to grow and spread. Leuprolide works by reducing the amount of testosterone that the body makes. This helps slow or stop the growth of cancer cells and helps relieve symptoms such as painful/difficult urination. Talk to your doctor about the risks and benefits of treatment. OTHER USES: This section contains uses of this drug that are not...
- Levocarnitine - SPL UNCLASSIFIED SECTION For oral use only. Not for parenteral use. DESCRIPTION CARNITOR ® (levocarnitine) is a carrier molecule in the transport of long-chain fatty acids across the inner mitochondrial membrane. The chemical name of levocarnitine is 3-carboxy-2( R )-hydroxy-N,N,N-trimethyl-1-propanaminium, inner salt. Levocarnitine...
- Levofloxacin - Indications and Usage Plague (1.14) 04/2012 Dosage and Administration Dosage in Adult Patients with Normal Renal Function (2.1) 04/2012 Dosage in Pediatric Patients (2.2) ...
- Levofloxacin; Dextrose
- Lorazepam - DESCRIPTION Each mL of Lorazepam Concentrate, USP for oral administration contains: Lorazepam . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2 mg Inactive Ingredients Lorazepam Oral Concentrate, USP contains polyethylene glycol, propylene glycol and triacetin. Lorazepam, an antianxiety agent, has the chemical formula, ...
- Lorazepam preservative free - Pharmacological action Lorazepam is an anxiolytic drug (tranquilizer), a derivative of benzodiazepine. This medication has anxiolytic, sedative, hypnotic, anticonvulsant, muscle relaxant central, antiemetic effect. The mechanism of the anxiolytic, sedative and hypnotic action is associated with increased inhibitory effect of GABA in the CNS. Anticonvulsant action, apparently in part due to increased presynaptic inhibition; inhibited the spread of epileptogenic activity arising in the...
- Melphalan - Dosage and Administration ( 2.4 ) 09/2017 WARNING: SEVERE BONE MARROW SUPPRESSION, HYPERSENSITIVITY, and LEUKEMOGENICITY • Severe bone marrow suppression with resulting infection...
- Mesna - 1 INDICATIONS AND USAGE MESNEX is indicated as a prophylactic agent in reducing the incidence of ifosfamide-induced hemorrhagic cystitis. Limitation of Use: MESNEX is not indicated to reduce the risk of hematuria due to other pathological conditions such as thrombocytopenia. MESNEX is a cytoprotective agent...
- Methotrexate - WARNING: SEVERE TOXIC REACTIONS, INCLUDING EMBRYO-FETAL TOXICITY Methotrexate can cause the following severe or fatal adverse reactions. Monitor closely and modify dose or discontinue methotrexate as appropriate. • Bone marrow suppression [see Warnings and...
- Methylprednisolone - DESCRIPTION Methylprednisolone Tablets contain methylprednisolone which is a glucocorticoid. Glucocorticoids are adrenocortical steroids, both naturally occurring and synthetic, which are readily absorbed from the gastrointestinal tract. Methylprednisolone occurs as a white to practically white, odorless, crystalline powder. It is sparingly soluble in alcohol, in dioxane, and in methanol, slightly soluble in acetone, and in chloroform, and very slightly...
- Metoclopramide - Boxed Warning 8/2017 Indications and Usage ( 1 ) 8/2017 Dosage and Administration, Dosage for Gastroesophageal Reflux ( 2.2 ) 8/2017 Dosage and Administration, Dosage for Acute and...
- Metoprolol - Pharmacological action Metoprolol is a cardioselective beta1-blocker without intrinsic sympathomimetic activity. This medication has antihypertensive, antianginal and antiarrhythmic effect. Metoprolol decreases automaticity of sinus node, reducing heart rate, slows AV-conduction, decreases myocardial contractility and excitability, reduces cardiac output, reduces myocardial oxygen demand. This drug inhibits the stimulatory effect of catecholamines on the heart during physical and...
- Midazolam - A short-acting hypnotic-sedative drug with anxiolytic and amnestic properties. It is used in dentistry, cardiac surgery, endoscopic procedures, as preanesthetic medication, and as an adjunct to local anesthesia. The short duration and cardiorespiratory stability makes it useful in poor-risk, elderly, and cardiac patients. It is water-soluble at pH less than 4 and lipid-soluble at physiological pH. [PubChem] Midazolam is a schedule IV drug in the United States. Indication: For use as a sedative...
- Milrinone - A positive inotropic cardiotonic agent with vasodilator properties. It inhibits cAMP phosphodiesterase activity in myocardium and vascular smooth muscle. Milrinone is a derivative of amrinone and has 20-30 times the ionotropic potency of amrinone. [PubChem] Indication: Indicated for the treatment of congestive heart failure. Milrinone, a synthetic dimethylxanthine derivative structurally related to theophylline and caffeine, is used in the treatment of peripheral vascular diseases and in the...
- Milrinone in Dextrose 5% in plastic container
- Mitomycin - SPL UNCLASSIFIED SECTION Rx only WARNING Mitomycin should be administered under the supervision of a qualified physician experienced in the use of cancer chemotherapeutic agents. Appropriate management of therapy and complications is possible only when adequate diagnostic and...
- Mitoxantrone - SPL UNCLASSIFIED SECTION Rx only WARNING Mitoxantrone Injection, USP (concentrate) should be administered under the supervision of a physician experienced in the use of cytotoxic chemotherapy agents. Mitoxantrone Injection, USP (concentrate) should be given slowly into a freely flowing intravenous infusion. It must never be given...
- Mycophenolate
- Nicardipine - A potent calcium channel blockader with marked vasodilator action. It has antihypertensive properties and is effective in the treatment of angina and coronary spasms without showing cardiodepressant effects. It has also been used in the treatment of asthma and enhances the action of specific antineoplastic agents. [PubChem] Indication: Used for the management of patients with chronic stable angina and for the treatment of hypertension. Nicardipine, a dihydropyridine calcium-channel blocker, is...
- Norepinephrine - Precursor of epinephrine that is secreted by the adrenal medulla and is a widespread central and autonomic neurotransmitter. Norepinephrine is the principal transmitter of most postganglionic sympathetic fibers and of the diffuse projection system in the brain arising from the locus ceruleus. It is also found in plants and is used pharmacologically as a sympathomimetic. [PubChem] Indication: Mainly used to treat patients in vasodilatory shock states such as septic shock and neurogenic shock and...
- Octreotide - Octreotide is the acetate salt of a cyclic octapeptide. It is a long-acting octapeptide with pharmacologic properties mimicking those of the natural hormone somatostatin. Indication: For treatment of acromegaly and reduction of side effects from cancer chemotherapy Octreotide exerts pharmacologic actions similar to the natural hormone, somatostatin. It is an even more potent inhibitor of growth hormone, glucagon, and insulin than somatostatin. Like somatostatin, it also suppresses leuteinizing...
- Octreotide preservative free
- Ofloxacin - Pharmacological action Ofloxacin is an antimicrobial agents of broad-spectrum action type from fluoroquinolone group. Bactericidal action of ofloxacin is due to blockage of the enzyme DNA gyrase in bacterial cells. This medication is highly active against most of gram-negative bacteria: Escherichia coli, Salmonella spp., Shigella spp., Proteus spp., Morganella morganii, Klebsiella spp. (including Klebsiella pneumoniae), Enterobacter spp., Serratia spp., Citrobacter spp., Yersinia spp.,...
- Ondansetron - Warnings and Precautions, ( 5.3 ) 09/2014 1 INDICATIONS AND USAGE ZUPLENZ is a 5-HT3 receptor antagonist indicated for: ...
- Ondansetron and Dextrose in plastic container
- Orphenadrine - A muscarinic antagonist used to treat drug-induced parkinsonism and to relieve pain from muscle spasm. [PubChem] Indication: Indicated for the treatment of Parkinson's disease. Orphenadrine is indicated as an adjunct to rest, physical therapy, and other measures for the relief of discomfort associated with acute painful musculoskeletal conditions. Orphenadrine is an anticholinergic with a predominantly central effect and only a weak peripheral effect. In addition, it has mild antihistaminic and...
- Paclitaxel - SPL UNCLASSIFIED SECTION OAS-OAS/PLV/60/US/PIL-001 237103 Paccal Vet ® -CA1 (paclitaxel for injection) 60 mg paclitaxel per vial Antineoplastic For intravenous use in dogs only Conditionally approved by FDA pending a full demonstration of effectiveness under application number 141-422. ...
- Pamidronate - Pamidronic acid (INN) or pamidronate disodium (USAN), marketed as pamidronate disodium pentahydrate under the brand name Aredia, is a bisphosphonate. [Wikipedia] Indication: For the treatment of moderate or severe hypercalcemia associated with malignancy Pamidronate is in a class of drugs called bisphosphonates. Pamidronate reduces breakdown of the bones. Pamidronate is used in the treatment of Paget's disease of bone; to reduce high levels of calcium in the blood associated with malignancy...
- Pentostatin - SPL UNCLASSIFIED SECTION NIPENT ™ (pentostatin for injection) SPL UNCLASSIFIED SECTION Rx only...
- Phentolamine - A nonselective alpha-adrenergic antagonist. It is used in the treatment of hypertension and hypertensive emergencies, pheochromocytoma, vasospasm of raynaud disease and frostbite, clonidine withdrawal syndrome, impotence, and peripheral vascular disease. [PubChem] Indication: Used as an aid for the diagnosis of pheochromocytoma, and may be administered immediately prior to or during pheochromocytomectomy to prevent or control paroxysmal hypertension resulting from anesthesia, stress, or...
- Polymyxin B - SPL UNCLASSIFIED SECTION To reduce the development of drug-resistant bacteria and maintain the effectiveness of Polymyxin and other antibacterial drugs, Polymyxin B for Injection should be used only to treat or prevent infections that are proven or strongly suspected to be caused by bacteria. WARNINGS CAUTION: WHEN THIS DRUG IS GIVEN INTRAMUSCULARLY,...
- Prochlorperazine - SPL UNCLASSIFIED SECTION ANTIEMETIC - TRANQUILIZER WARNING SPL UNCLASSIFIED SECTION Increased Mortality in Elderly Patients with Dementia-Related Psychosis Elderly patients with dementia-related psychosis treated with antipsychotic drugs are at an increased risk of death. Analyses of seventeen placebo-controlled trials...
- Promethazine - A phenothiazine derivative with histamine H1-blocking, antimuscarinic, and sedative properties. It is used as an antiallergic, in pruritus, for motion sickness and sedation, and also in animals. [PubChem] Indication: For the treatment of allergic disorders, and nausea/vomiting. Promethazine, a phenothiazine, is an H1-antagonist with anticholinergic, sedative, and antiemetic effects and some local anesthetic properties. Promethazine is used as an antiemetic or to prevent motion sickness.
- Propofol - SPL UNCLASSIFIED SECTION For Animals Only VETONE ® Propovan™ CF (propofol injectable emulsion) Anesthetic Injection Each mL contains 10 mg propofol NADA 141-070 ...
- Propranolol - Pharmacological action Propranolol is a non-selective beta-blocker. This medication has antihypertensive, antianginal and antiarrhythmic action. The hypotensive effect is associated with a decrease in minute volume of blood, sympathetic stimulation of peripheral vascular disease, decreased activity of the renin-angiotensin system (has a value in patients with initial hypersecretion of renin), sensitivity of baroreceptors of the aortic arch (not going to enhance their activity in response...
- Ranitidine - Pharmacological action Ranitidine is a blocker of histamine H2-receptors. Inhibits basal and stimulated by histamine, gastrin and acetylcholine (to a lesser extent) the secretion of hydrochloric acid. Increases the pH of gastric contents and reduces the activity of pepsin. The duration of action of ranitidine with a single admission - 12 hours. Pharmacokinetics After oral administration, ranitidine is rapidly absorbed from the gastrointestinal tract. Eating and antacids significantly...
- Rifampin - SPL UNCLASSIFIED SECTION Rx Only SPL UNCLASSIFIED SECTION To reduce the development of drug-resistant bacteria and maintain the effectiveness of rifampin for injection, USP and other antibacterial drugs, rifampin should be used only to treat or prevent infections that are proven or strongly suspected to be caused by bacteria. ...
- Sulfamethoxazole; Trimethoprim
- Sumatriptan - Pharmacological action Sumatriptan is a drug in tablet pharmaceutical form that has sumatriptan as the active element. This drug under trade name Imitrex also contains inactive elements such as the following: croscarmellose sodium; dibasic calcium phosphate; magnesium stearate; microcrystalline cellulose; sodium bicarbonate; hypromellose; iron oxide; titanium dioxide; traction Sumatriptan is a drug used to alleviate the headache brought about by migraine attacks. Why is Sumatriptan...
- Terbinafine - Terbinafine information Terbinafine is an antifungal drug used as athlete's foot medication. Terbinafine works like an antibiotic to treat fungal infections. Terbinafine indications This medicine is mainly indicated to treat fungal infections of the fingernails and toenails. Terbinafine may also be used for purposes not mentioned here. Terbinafine warnings This drug is classed as a FDA pregnancy category B drug and may cause severe side effects to an unborn baby. Consult with your...
- Testosterone - DESCRIPTION TESTOPEL ® (testosterone pellets) are cylindrically shaped pellets 3.2mm (1/8 inch) in diameter and approximately 9mm in length. Each sterile pellet weighs approximately 78mg (75mg testosterone) and is ready for implantation. Androgens are steroids that develop and maintain primary and secondary male sex...
- Thiotepa - WARNING: SEVERE MYELOSUPPRESSION, CARCINOGENICITY TEPADINA may cause severe marrow suppression, and high doses may cause marrow ablation with resulting infection or bleeding. Monitor hematologic laboratory parameters. Hematopoietic progenitor (stem) cell transplantation (HSCT) is required to prevent potentially fatal complications of the prolonged...
- Torsemide - 1 INDICATIONS AND USAGE Torsemide is a loop diuretic indicated for: the treatment of edema associated with heart failure, renal disease or hepatic disease. ( 1.1 ) the treatment of hypertension, to lower blood pressure. Lowering blood pressure reduces the risk of fatal and nonfatal cardiovascular events, primarily strokes and myocardial...
- Valproate
- Vecuronium Bromide - SPL UNCLASSIFIED SECTION for Injection Rx only [BOXED WARNING SECTION] THIS DRUG SHOULD BE ADMINISTERED BY ADEQUATELY TRAINED INDIVIDUALS FAMILIAR WITH ITS ACTIONS, CHARACTERISTICS, AND HAZARDS. DESCRIPTION Vecuronium bromide for injection is a...
- Verapamil - A calcium channel blocker that is a class IV anti-arrhythmia agent. [PubChem] Indication: For the treatment of hypertension, angina, and cluster headache prophylaxis. Verapamil is an L-type calcium channel blocker that also has antiarrythmic activity. The R-enantiomer is more effective at reducing blood pressure compared to the S-enantiomer. However, the S-enantiomer is 20 times more potent than the R-enantiomer at prolonging the PR interval in treating arrhythmias.
- Vinblastine - Antitumor alkaloid isolated from Vinca rosea. (Merck, 11th ed.) Indication: For treatment of breast cancer, testicular cancer, lymphomas, neuroblastoma, Hodgkin's and non-Hodgkin's lymphomas, mycosis fungoides, histiocytosis, and Kaposi's sarcoma. Vinblastine is a vinca alkaloid antineoplastic agent. The vinca alkaloids are structurally similar compounds comprised of 2 multiringed units: vindoline and catharanthine. The vinca alkaloids have become clinically useful since the discovery of their...
- Vinorelbine - WARNING: MYELOSUPPRESSION Severe myelosuppression resulting in serious infection, septic shock, hospitalization and death may occur [see Warnings and Precautions (5.1) ]. Decrease the dose or withhold vinorelbine in accord with recommended dose modifications [see Dosage and Administration (2.2) ]. ...
- Zoledronic Acid - 1 INDICATIONS AND USAGE Reclast is a bisphosphonate indicated for: Treatment and prevention of postmenopausal osteoporosis ( 1.1 , 1.2 ) Treatment to increase bone mass in men with osteoporosis ( 1.3 ) Treatment and prevention of glucocorticoid-induced osteoporosis ( 1.4 ) ...
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The information was verified by Dr. Rachana Salvi, MD Pharmacology
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