Ampimax

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Ampimax uses


Pharmacological action

Ampimax is an antibiotic of semisynthetic broad-spectrum penicillin group. This medication has a bactericidal effect by suppressing the synthesis of bacterial cell walls. Ampimax is active against aerobic gram-positive bacteria: Staphylococcus spp., Streptococcus spp., Enterococcus spp., Listeria monocytogenes; aerobic gram-negative bacteria: Neisseria gonorrhoeae, Neisseria meningitidis, Escherichia coli, Shigella spp., Salmonella spp., Bordetella pertussis, some strains of Haemophilus influenzae. Ampimax destroyed by penicillinase. This drug is acid-resistant.

Pharmacokinetics

After oral administration Ampimax is well absorbed from the gastrointestinal tract. This medicine is distributed in most organs and tissues; crosses the placental barrier, poorly penetrates the BBB. When inflammation of the meninges, BBB permeability increases dramatically. 30% of Ampimax is metabolized in the liver. This medication is excreted in the urine and bile.

Why is Ampimax prescribed?

Infectious-inflammatory diseases caused by organisms susceptible to Ampimax: including ear infections, throat, nose, odontogenic infections, bronchopulmonary infections, acute and chronic urinary tract infections, gastrointestinal infections, gynecological infections, meningitis, endocarditis, septicemia, sepsis, rheumatic fever, erysipelas, scarlet fever, infections of skin and soft tissues.

Dosage and administration

The dosing regimen of Ampimax is set individually depending on the severity, localization of infection and sensitivity of the pathogen.

For adults for oral administration a single dose of this medication is 250-500 mg, the multiplicity of the reception is 4 times / day. The dose for children weighing up to 20 kg is 12.5-25 mg / kg every 6 hours.

For IV and IM using the single dose for adults is 250-500 mg every 4-6 hours; for children the single dose is 25-50 mg / kg.

The duration of treatment depends on the localization of infection and features of the disease.

The maximum oral daily dose for adults is 4 g, for IM and IV administration - 14 g.

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Ampimax side effects, adverse reactions

Allergic reactions: urticaria, erythema, angioedema, rhinitis, conjunctivitis, rarely - fever, joint pain, eosinophilia, extremely rare - anaphylactic shock.

Digestive system: nausea, vomiting.

The effects caused by chemotherapeutic action: oral candidiasis, vaginal candidiasis, intestinal dysbiosis, colitis caused by Clostridium difficile.

Ampimax contraindications

Infectious mononucleosis, lymphatic leukemia, increased sensitivity to Ampimax and other penicillins, abnormal liver function.

Using during pregnancy and breastfeeding

Perhaps the use of Ampimax during pregnancy if it may be needed. Ampimax is excreted in breast milk in low concentrations. If necessary to use Ampimax in the lactation period it should be solved the issue of termination of breastfeeding.

Category effects on the fetus by FDA - B.

Special instructions

In the course of treatment with Ampimax there is need the regular control of renal function, liver and peripheral blood picture. Patients with impaired renal function requires correction dosing regimen in accordance with the values of CCr.

When used in high doses in patients with renal insufficiency it may be toxic effects on the CNS.

For using of Ampimax in patients with bacteremia it can be bacteriolysis reaction (Jarisch-Herxheimer reaction).

Ampimax drug interactions

Simultaneous administration of Ampimax with bactericidal antibiotics (including aminoglycosides, cephalosporins, cycloserine, vancomycin, rifampicin) there is manifested synergism; with bacteriostatic antibiotics (including macrolides, chloramphenicol, lincosamides, tetracyclines, sulfonamides) - antagonism.

Ampimax enhances the effect of indirect anticoagulants by inhibiting the intestinal microflora, reduces the synthesis of vitamin K and prothrombin index.

Ampimax decreases the effect of drugs in the process of metabolism which produce PABA.

Probenecid, diuretics, allopurinol, phenylbutazone, NSAIDs decrease the tubular secretion of Ampimax which may be accompanied by an increase in its concentration in blood plasma.

Antacids, glucosamine, laxatives, aminoglycosides slow down and reduce the absorption of Ampimax Upha Corporation. Ascorbic acid increases the absorption of Ampimax.

Ampimax decreases the effectiveness of oral contraceptives.

Ampimax in case of emergency / overdose

Symptoms: the toxic effect on the central nervous system (especially in patients with renal insufficiency), nausea, vomiting, diarrhea, impaired water and electrolyte balance (as a consequence of vomiting and diarrhea).

Treatment: gastric lavage, activated charcoal, saline laxatives, a maintain of water and electrolyte balance, symptomatic therapy. This drug is derived by means of hemodialysis.

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Ampimax pharmaceutical active ingredients containing related brand and generic drugs:


Ampimax available forms, composition, doses:


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Ampimax Anatomical Therapeutic Chemical codes:


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References

  1. Dailymed."AMPICILLIN SODIUM: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailym... (accessed August 28, 2018).
  2. "ampicillin". https://pubchem.ncbi.nlm.nih.gov/co... (accessed August 28, 2018).
  3. "ampicillin". http://www.drugbank.ca/drugs/DB0041... (accessed August 28, 2018).

Frequently asked Questions

Can i drive or operate heavy machine after consuming Ampimax?

Depending on the reaction of the Ampimax after taken, if you are feeling dizziness, drowsiness or any weakness as a reaction on your body, Then consider Ampimax not safe to drive or operate heavy machine after consumption. Meaning that, do not drive or operate heavy duty machines after taking the capsule if the capsule has a strange reaction on your body like dizziness, drowsiness. As prescribed by a pharmacist, it is dangerous to take alcohol while taking medicines as it exposed patients to drowsiness and health risk. Please take note of such effect most especially when taking Primosa capsule. It's advisable to consult your doctor on time for a proper recommendation and medical consultations.

Is Ampimax addictive or habit forming?

Medicines are not designed with the mind of creating an addiction or abuse on the health of the users. Addictive Medicine is categorically called Controlled substances by the government. For instance, Schedule H or X in India and schedule II-V in the US are controlled substances.

Please consult the medicine instruction manual on how to use and ensure it is not a controlled substance.In conclusion, self medication is a killer to your health. Consult your doctor for a proper prescription, recommendation, and guidiance.

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Review

sdrugs.com conducted a study on Ampimax, and the result of the survey is set out below. It is noteworthy that the product of the survey is based on the perception and impressions of the visitors of the website as well as the views of Ampimax consumers. We, as a result of this, advice that you do not base your therapeutic or medical decisions on this result, but rather consult your certified medical experts for their recommendations.

Visitor reports

Visitor reported useful

No survey data has been collected yet

Visitor reported side effects

No survey data has been collected yet

One visitor reported price estimates

What is your opinion about drug cost? Did you feel the cost is apt, or did you feel it is expensive?
The report given by the sdrugs.com website users shows the following figures about several people who felt the medicine Ampimax is expensive, and the medicine is not expensive. The results are mixed. The perception of the cost of the medicine to be expensive or not depends on the brand name of the medicine, country, and place where it is sold, and the affordability of the patient. You can choose a generic drug in the place of the branded drug to save the cost. The efficiency of the medicine will not vary if it is generic or a branded one.
Visitors%
Not expensive1
100.0%

Four visitors reported frequency of use

How often in a day do you take the medicine?
Are you taking the Ampimax drug as prescribed by the doctor?

Few medications can be taken Twice in a day more than prescribed when the doctor's advice mentions the medicine can be taken according to frequency or severity of symptoms. Most times, be very careful and clear about the number of times you are taking the medication. The report of sdrugs.com website users about the frequency of taking the drug Ampimax is mentioned below.
Visitors%
Twice in a day3
75.0%
Once in a day1
25.0%

Two visitors reported doses

What is the dose of Ampimax drug you are taking?
According to the survey conducted among sdrugs.com website users, the maximum number of people are using the following dose 501mg-1g. Few medications come in only one or two doses. Few are specific for adult dose and child dose. The dose of the medicine given to the patient depends on the severity of the symptom/disease. There can be dose adjustments made by the doctor, based on the progression of the disease. Follow-up is important.
Visitors%
501mg-1g2
100.0%

Three visitors reported time for results

What is the time duration Ampimax drug must be taken for it to be effective or for it to reduce the symptoms?
Most chronic conditions need at least some time so the dose and the drug action gets adjusted to the body to get the desired effect. The stastistics say sdrugs.com website users needed 5 days to notice the result from using Ampimax drug. The time needed to show improvement in health condition after using the medicine Ampimax need not be same for all the users. It varies based on other factors.
Visitors%
5 days3
100.0%

One visitor reported administration

The drugs are administered in various routes, like oral or injection form. They are administered before food or after food. How are you taking Ampimax drug, before food or after food?
Click here to find out how other users of our website are taking it. For any doubts or queries on how and when the medicine is administered, contact your health care provider immediately.
Visitors%
Before food1
100.0%

Three visitors reported age

Visitors%
16-292
66.7%
30-451
33.3%

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The information was verified by Dr. Rachana Salvi, MD Pharmacology

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