Active ingredient: L-Tryptophan

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L-Tryptophan uses

An essential amino acid that is necessary for normal growth in infants and for nitrogen balance in adults. It is a precursor of indole alkaloids in plants. It is a precursor of serotonin (hence its use as an antidepressant and sleep aid). It can be a precursor to niacin, albeit inefficiently, in mammals.

Indication: Tryptophan may be useful in increasing serotonin production, promoting healthy sleep, managing depression by enhancing mental and emotional well-being, managing pain tolerance, and managing weight.

Tryptophan is critical for the production of the body's proteins, enzymes and muscle tissue. It is also essential for the production of niacin, the synthesis of the neurotransmitter serotonin and melatonin. Tryptophan supplements can be used as natural relaxants to help relieve insomnia. Tryptophan can also reduce anxiety and depression and has been shown to reduce the intensity of migraine headaches. Other promising indications include the relief of chronic pain, reduction of impulsivity or mania and the treatment of obsessive or compulsive disorders. Tryptophan also appears to help the immune system and can reduce the risk of cardiac spasms. Tryptophan deficiencies may lead to coronary artery spasms. Tryptophan is used as an essential nutrient in infant formulas and intravenous feeding. Tryptophan is marketed as a prescription drug (Tryptan) for those who do not seem to respond well to conventional antidepressants. It may also be used to treat those afflicted with seasonal affective disorder (a winter-onset depression). Tryptopan serves as the precursor for the synthesis of serotonin (5-hydroxytryptamine, 5-HT) and melatonin (N-acetyl-5-methoxytryptamine).


L-Tryptophan available forms, composition, doses:

Apo-Tryptophan 1 g Tablet0.9 USD
Apo-Tryptophan 500 mg Capsule0.45 USD
Apo-Tryptophan 500 mg Tablet0.45 USD
L-tryptophan 500 mg capsule0.33 USD
L-tryptophan crystals0.72 USD
Pms-Tryptophan 500 mg Capsule0.45 USD
Pms-Tryptophan 500 mg Tablet0.45 USD
Ratio-Tryptophan 1 g Tablet0.9 USD
Ratio-Tryptophan 500 mg Capsule0.45 USD
Ratio-Tryptophan 500 mg Tablet0.45 USD
Tablets, Film-Coated; Oral; L-Tryptophan
Tryptan 1 g Tablet1.6 USD
Tryptan 250 mg Tablet0.4 USD
Tryptan 500 mg Capsule0.8 USD
Tryptan 500 mg Tablet0.8 USD
Tryptan 750 mg Tablet1.2 USD

Indications and Usages:

ATC codes:

ICD-10 codes:

L-Tryptophan destination | category:


Drugs with same active ingredients (Pharmaceutical companies):


  1. "L-tryptophan". https://pubchem.ncbi.nlm.nih.gov/co... (accessed August 28, 2018).
  2. "L-tryptophan". http://www.drugbank.ca/drugs/DB0015... (accessed August 28, 2018).
  3. "8DUH1N11BX: The UNique Ingredient Identifier (UNII) is an alphanumeric substance identifier from the joint FDA/USP Substance Registration System (SRS).". https://www.fda.gov/ForIndustry/Dat... (accessed August 28, 2018).

Frequently asked Questions

Can i drive or operate heavy machine after consuming L-Tryptophan?

Depending on the reaction of the L-Tryptophan after taken, if you are feeling dizziness, drowsiness or any weakness as a reaction on your body, Then consider L-Tryptophan not safe to drive or operate heavy machine after consumption. Meaning that, do not drive or operate heavy duty machines after taking the capsule if the capsule has a strange reaction on your body like dizziness, drowsiness. As prescribed by a pharmacist, it is dangerous to take alcohol while taking medicines as it exposed patients to drowsiness and health risk. Please take note of such effect most especially when taking Primosa capsule. It's advisable to consult your doctor on time for a proper recommendation and medical consultations.

Is L-Tryptophan addictive or habit forming?

Medicines are not designed with the mind of creating an addiction or abuse on the health of the users. Addictive Medicine is categorically called Controlled substances by the government. For instance, Schedule H or X in India and schedule II-V in the US are controlled substances.

Please consult the medicine instruction manual on how to use and ensure it is not a controlled substance.In conclusion, self medication is a killer to your health. Consult your doctor for a proper prescription, recommendation, and guidiance.



sDrugs.com conducted a study on L-Tryptophan, and the result of the survey is set out below. It is noteworthy that the product of the survey is based on the perception and impressions of the visitors of the website as well as the views of L-Tryptophan consumers. We, as a result of this, advice that you do not base your therapeutic or medical decisions on this result, but rather consult your certified medical experts for their recommendations.

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The information was verified by Dr. Arunabha Ray, MD Pharmacology

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