Active ingredient: Isosorbide Mononitrate

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Isosorbide Mononitrate uses

Isosorbide Mononitrate is a drug used principally in the treatment of angina pectoris1 and acts by dilating the blood vessels so as to reduce the blood pressure. It is sold by AstraZeneca under the trade name Imdur. Isosorbide mononitrate is used to for the the prophylactic treatment of angina pectoris; that is, it is taken in order to prevent or at least reduce the occurrence of angina. Research on Isosorbide Mononitrate as a cervical ripener to reduce time at hospital to birth is supportive. Isosorbide mononitrate is an active metabolite of isosorbide dinitrate and exerts qualitatively similar effects. Isosorbide Mononitrate reduces the workload of the heart by producing venous and arterial dilation. By reducing the end diastolic pressure and volume, Isosorbide Mononitrate lowers intramural pressure, hence leading to an improvement in the subendocardial blood flow. The net effect when administering Isosorbide Mononitrate is therefore a reduced workload for the heart and an improvement in the oxygen supply/demand balance of the myocardium. The adverse reactions which follow have been reported in studies with Isosorbide Mononitrate:Very common. Headache predominates (up to 30%) necessitating withdrawal of 2 to 3 % of patients, but the incidence reduces rapidly as treatment continues. Common. Tiredness, sleep disturbances (6%) and gastrointestinal disturbances (6%) have been reported during clinical trials with Isosorbide Mononitrate modified release tablets, but at a frequency no greater than for placebo. Hypotension (4 to 5%), poor appetite (2.5%), nausea (1%).Adverse effects associated with the clinical use of the drug are as expected with all nitrate preparations. They occur mainly in the early stages of treatment. Hypotension (4%) with symptoms such as dizziness and nausea (1%) have been reported. These symptoms generally disappear during long-term treatment. Other reactions that have been reported with Isosorbide Mononitrate modified release tablets include tachycardia, vomiting, diarrhoea, vertigo and heartburn

Indication: For the prevention of angina pectoris due to coronary artery disease and the treatment of acute and chronic angina pectoris, hypertension, and myocardial infarction.

Isosorbide-5-mononitrate, the long-acting metabolite of isosorbide dinitrate, is used as a vasodilatory agent in the management of angina pectoris. By dilating the vessels, it lowers the blood pressure and reduces the left ventricular preload and afterload, therefore, leads to a reduction of myocardial oxygen requirement.


Isosorbide Mononitrate available forms, composition, doses:

Apo-Ismn 60 mg Extended-Release Tablet0.42 USD
Capsules; Oral; Isosorbide Mononitrate 20 mg
Capsules; Oral; Isosorbide Mononitrate 25 mg
Capsules; Oral; Isosorbide Mononitrate 40 mg
Capsules; Oral; Isosorbide Mononitrate 50 mg
Imdur 120 mg 24 Hour tablet3.15 USD
Imdur 30 mg 24 Hour tablet2.87 USD
Imdur 60 mg 24 Hour tablet3.11 USD
Imdur 60 mg Extended-Release Tablet0.74 USD
Imdur er 120 mg tablet4.19 USD
Imdur er 30 mg tablet2.85 USD
Imdur er 60 mg tablet2.99 USD
Ismo 20 mg tablet2.1 USD
Isosorbide Mononitrate 10 mg tablet0.74 USD
Isosorbide Mononitrate 20 mg tablet0.78 USD
Isosorbide Mononitrate CR 30 mg 24 Hour tablet1.16 USD
Isosorbide Mononitrate CR 60 mg 24 Hour tablet1.48 USD
Isosorbide mn 10 mg tablet0.71 USD
Isosorbide mn 20 mg tablet0.72 USD
Monoket 10 mg tablet1.75 USD
Monoket 20 mg tablet2.65 USD
Pms-Ismn 60 mg Extended-Release Tablet0.42 USD
Tablets, Extended Release; Oral; Isosorbide Mononitrate 120 mg
Tablets, Extended Release; Oral; Isosorbide Mononitrate 30 mg
Tablets, Extended Release; Oral; Isosorbide Mononitrate 60 mg
Tablets, Modified Release; Oral; Isosorbide Mononitrate 60 mg
Tablets; Oral; Isosorbide Mononitrate 10 mg
Tablets; Oral; Isosorbide Mononitrate 20 mg

Indications and Usages:

ATC codes:

ICD-10 codes:

Isosorbide Mononitrate destination | category:


Drugs with same active ingredients (Pharmaceutical companies):


  2. Dailymed."ISOSORBIDE MONONITRATE: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". (accessed August 28, 2018).
  3. "ISOSORBIDE MONONITRATE". (accessed August 28, 2018).

Frequently asked Questions

Can i drive or operate heavy machine after consuming Isosorbide Mononitrate?

Depending on the reaction of the Isosorbide Mononitrate after taken, if you are feeling dizziness, drowsiness or any weakness as a reaction on your body, Then consider Isosorbide Mononitrate not safe to drive or operate heavy machine after consumption. Meaning that, do not drive or operate heavy duty machines after taking the capsule if the capsule has a strange reaction on your body like dizziness, drowsiness. As prescribed by a pharmacist, it is dangerous to take alcohol while taking medicines as it exposed patients to drowsiness and health risk. Please take note of such effect most especially when taking Primosa capsule. It's advisable to consult your doctor on time for a proper recommendation and medical consultations.

Is Isosorbide Mononitrate addictive or habit forming?

Medicines are not designed with the mind of creating an addiction or abuse on the health of the users. Addictive Medicine is categorically called Controlled substances by the government. For instance, Schedule H or X in India and schedule II-V in the US are controlled substances.

Please consult the medicine instruction manual on how to use and ensure it is not a controlled substance.In conclusion, self medication is a killer to your health. Consult your doctor for a proper prescription, recommendation, and guidiance.


Review conducted a study on Isosorbide Mononitrate, and the result of the survey is set out below. It is noteworthy that the product of the survey is based on the perception and impressions of the visitors of the website as well as the views of Isosorbide Mononitrate consumers. We, as a result of this, advice that you do not base your therapeutic or medical decisions on this result, but rather consult your certified medical experts for their recommendations.

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What is the dose of Isosorbide Mononitrate drug you are taking?
According to the survey conducted among website users, the maximum number of people are using the following dose 51-100mg. Few medications come in only one or two doses. Few are specific for adult dose and child dose. The dose of the medicine given to the patient depends on the severity of the symptom/disease. There can be dose adjustments made by the doctor, based on the progression of the disease. Follow-up is important.

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The information was verified by Dr. Rachana Salvi, MD Pharmacology

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