Active ingredient: Fluconazole

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Fluconazole uses

Pharmacological action

Fluconazole is an antifungal drug from the group of triazole derivatives. Inhibits the synthesis of ergosterol disrupting the permeability of the cell wall. This medication is active against Candida, Microsporum, Cryptococcus neoformans, Trichophyton.


Fluconazole is well absorbed after oral administration. Simultaneous ingestion does not affect absorption. The bioavailability is 90%. Fluconazole is widely distributed in tissues and organs of the body. Its concentration in breast milk, joint fluid, saliva, sputum, vaginal secretions and peritoneal fluid are similar to those in blood plasma. The concentration in the cerebrospinal fluid is 50-90% of the level in blood plasma, regardless of the presence of inflammation of the meninges. In the stratum corneum, epidermis, dermis and sweat fluid concentrations reach values exceeding the concentration in blood plasma. T1/2 is 30 h. Fluconazole is excreted by the kidneys, 80% of the administered dose in an unmodified form.

Why is Fluconazole prescribed?

Cryptococcosis, systemic candidiasis, candidiasis of the mucous membranes, vaginal candidiasis, prevention of fungal infections in patients with lowered immunity (including AIDS patients). Fungal infections of skin, including athlete's foot, body, groin, pityriasis versicolor, onychomycosis. Deep endemic mycoses, including coccidioidomycosis, paracoccidioidomycosis, sporotrichosis and histoplasmosis in patients with normal immunity.

Dosage and administration

Dosing regimen of Fluconazole is individual. This medication is prescribed for oral and IV administration. Depending on the testimony of the daily dose is 50-400 mg, the multiplicity of application is 1 times / day. If impaired renal function the dose of Fluconazole should be reduced.

Fluconazole side effects, adverse reactions

Digestive system: nausea, abdominal pain, diarrhea, flatulence.

CNS: headache, dizziness.

Allergic reactions: skin rash, anaphylactic reactions.


Fluconazole contraindications

Pregnancy, children up to age 1 year, increased sensitivity to Fluconazole and triazole compounds.

Using during pregnancy and breastfeeding

Fluconazole is contraindicated during pregnancy and lactation.

If necessary using this medication during lactation it should solve the issue of termination of breastfeeding. Category effects on the fetus by FDA - C.

Special instructions

Fluconazole should be used with caution in patients with severe impaired liver or kidney diseases.

Therapy can be started before the results of seeding and other laboratory tests. However, an anti-infective therapy should be corrected accordingly when the results of these studies will be known.

Fluconazole drug interactions

Simultaneous administration of Fluconazole with:

  • coumarin anticoagulants marked increase in prothrombin time.
  • rifampicin observed shortening of the half-life of Fluconazole. Fluconazole Sorres Pharma increases the half-life of oral hypoglycemic agents - sulfonylureas in healthy people. Simultaneous use of Fluconazole and oral hypoglycemic agents in diabetic patients is allowed, however, the physician should bear in mind the possibility of hypoglycemia.

    Fluconazole in case of emergency / overdose

    Symptoms: nausea, vomiting, diarrhea and seizures in severe cases.

    Treatment: gastric lavage, forced diuresis, hemodialysis (three-hour dialysis reduces the plasma concentrations of approximately 50%), symptomatic therapy.


    Fluconazole available forms, composition, doses:

    Apo-Fluconazole 100 mg Tablet5.81 USD
    Apo-Fluconazole 50 mg Tablet3.28 USD
    Apo-Fluconazole-150 150 mg Capsule9.18 USD
    Capsules; Oral; Fluconazole 100 mg
    Capsules; Oral; Fluconazole 150 mg
    Capsules; Oral; Fluconazole 200 mg
    Capsules; Oral; Fluconazole 50 mg
    Co Fluconazole 100 mg Tablet5.42 USD
    Co Fluconazole 150 mg Capsule9.18 USD
    Co Fluconazole 50 mg Tablet3.06 USD
    Diflucan 10 mg/ml Suspension 35ml Bottle56.06 USD
    Diflucan 100 mg tablet12.61 USD
    Diflucan 150 mg Capsule16.44 USD
    Diflucan 150 mg tablet24.71 USD
    Diflucan 2 mg/ml0.6 USD
    Diflucan 200 mg tablet20.82 USD
    Diflucan 40 mg/ml Suspension 35ml Bottle203.65 USD
    Diflucan 50 mg tablet8.05 USD
    Diflucan-dextr 200 mg/100 ml1.28 USD
    Diflucan-saline 200 mg/100 ml1.28 USD
    Fluconazole 10 mg/ml Suspension 35ml Bottle35.94 USD
    Fluconazole 100 mg tablet8.95 USD
    Fluconazole 150 mg tablet13.93 USD
    Fluconazole 2 mg/ml0.33 USD
    Fluconazole 200 mg tablet14.26 USD
    Fluconazole 40 mg/ml Suspension 35ml Bottle135.99 USD
    Fluconazole 50 mg tablet5.7 USD
    Fluconazole Omega 2 mg/ml0.33 USD
    Fluconazole powder14.08 USD
    Fluconazole-dext 200 mg/100 ml0.32 USD
    Fluconazole-ns 200 mg/100 ml0.19 USD
    Injectable; Infusion; Fluconazole 2 mg / ml
    Injectable; Injection; Fluconazole 2 mg / ml
    Mylan-Fluconazole 100 mg Tablet5.81 USD
    Mylan-Fluconazole 150 mg Capsule9.18 USD
    Mylan-Fluconazole 50 mg Tablet3.28 USD
    Novo-Fluconazole 100 mg Tablet5.42 USD
    Novo-Fluconazole 50 mg Tablet3.06 USD
    Pms-Fluconazole 100 mg Tablet5.42 USD
    Pms-Fluconazole 150 mg Capsule9.18 USD
    Pms-Fluconazole 50 mg Tablet3.06 USD
    Powder for Suspension; Oral; Fluconazole 200 mg / 5 ml
    Powder for Suspension; Oral; Fluconazole 50 mg / 5 ml
    Tablets, Film-Coated; Oral; Fluconazole 100 mg
    Tablets, Film-Coated; Oral; Fluconazole 150 mg
    Tablets, Film-Coated; Oral; Fluconazole 50 mg
    Tablets; Oral; Fluconazole 100 mg
    Tablets; Oral; Fluconazole 150 mg
    Tablets; Oral; Fluconazole 200 mg
    Tablets; Oral; Fluconazole 50 mg


    Indications and Usages:

    ATC codes:

    ICD-10 codes:

    Fluconazole destination | category:


    Drugs with same active ingredients (Pharmaceutical companies):


    1. Dailymed."FLUCONAZOLE TABLET [BRYANT RANCH PREPACK]". (accessed August 28, 2018).
    2. Dailymed."FLUCONAZOLE: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". (accessed August 28, 2018).
    3. "fluconazole". (accessed August 28, 2018).

    Frequently asked Questions

    Can i drive or operate heavy machine after consuming Fluconazole?

    Depending on the reaction of the Fluconazole after taken, if you are feeling dizziness, drowsiness or any weakness as a reaction on your body, Then consider Fluconazole not safe to drive or operate heavy machine after consumption. Meaning that, do not drive or operate heavy duty machines after taking the capsule if the capsule has a strange reaction on your body like dizziness, drowsiness. As prescribed by a pharmacist, it is dangerous to take alcohol while taking medicines as it exposed patients to drowsiness and health risk. Please take note of such effect most especially when taking Primosa capsule. It's advisable to consult your doctor on time for a proper recommendation and medical consultations.

    Is Fluconazole addictive or habit forming?

    Medicines are not designed with the mind of creating an addiction or abuse on the health of the users. Addictive Medicine is categorically called Controlled substances by the government. For instance, Schedule H or X in India and schedule II-V in the US are controlled substances.

    Please consult the medicine instruction manual on how to use and ensure it is not a controlled substance.In conclusion, self medication is a killer to your health. Consult your doctor for a proper prescription, recommendation, and guidiance.


    Review conducted a study on Fluconazole, and the result of the survey is set out below. It is noteworthy that the product of the survey is based on the perception and impressions of the visitors of the website as well as the views of Fluconazole consumers. We, as a result of this, advice that you do not base your therapeutic or medical decisions on this result, but rather consult your certified medical experts for their recommendations.

    Visitor reports

    Visitor reported useful

    No survey data has been collected yet

    Visitor reported side effects

    No survey data has been collected yet

    Two visitors reported price estimates

    What is your opinion about drug cost? Did you feel the cost is apt, or did you feel it is expensive?
    The report given by the website users shows the following figures about several people who felt the medicine Fluconazole is expensive, and the medicine is not expensive. The results are mixed. The perception of the cost of the medicine to be expensive or not depends on the brand name of the medicine, country, and place where it is sold, and the affordability of the patient. You can choose a generic drug in the place of the branded drug to save the cost. The efficiency of the medicine will not vary if it is generic or a branded one.
    Not expensive2

    Two visitors reported frequency of use

    How often in a day do you take the medicine?
    Are you taking the Fluconazole drug as prescribed by the doctor?

    Few medications can be taken Once in a day more than prescribed when the doctor's advice mentions the medicine can be taken according to frequency or severity of symptoms. Most times, be very careful and clear about the number of times you are taking the medication. The report of website users about the frequency of taking the drug Fluconazole is mentioned below.
    Once in a day2

    Two visitors reported doses

    What is the dose of Fluconazole drug you are taking?
    According to the survey conducted among website users, the maximum number of people are using the following dose 101-200mg. Few medications come in only one or two doses. Few are specific for adult dose and child dose. The dose of the medicine given to the patient depends on the severity of the symptom/disease. There can be dose adjustments made by the doctor, based on the progression of the disease. Follow-up is important.

    Two visitors reported time for results

    What is the time duration Fluconazole drug must be taken for it to be effective or for it to reduce the symptoms?
    Most chronic conditions need at least some time so the dose and the drug action gets adjusted to the body to get the desired effect. The stastistics say website users needed 3 month to notice the result from using Fluconazole drug. The time needed to show improvement in health condition after using the medicine Fluconazole need not be same for all the users. It varies based on other factors.
    3 month1
    > 3 month1

    Two visitors reported administration

    The drugs are administered in various routes, like oral or injection form. They are administered before food or after food. How are you taking Fluconazole drug, before food or after food?
    Click here to find out how other users of our website are taking it. For any doubts or queries on how and when the medicine is administered, contact your health care provider immediately.
    After food1
    Empty stomach1

    Three visitors reported age


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    The information was verified by Dr. Arunabha Ray, MD Pharmacology

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