Active ingredient: Dextromethorphan

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Dextromethorphan uses


Pharmacological action

dextromethorphan is an antitussive medication. Inhibiting the excitability of the cough center this medicine suppresses the cough of any origin. dextromethorphan has not addiction effects and it has no analgesic and hypnotic action. dextromethorphan starts to act after 10-30 minutes after oral administration, the duration of therapeutic action: 5-6 hours for adults and 6-9 hours for children. dextromethorphan is an optical isomer of levomethorphan which is similar to morphine. Due to optical isomerism this drug has no opioid effects. dextromethorphan used mainly for replacement of codeine as a cough suppressant. In addition to the cough suppressant this medication is used in medicine for diagnostic purposes and may be useful in various cases - from seizures to heroin addiction treatment, some chronic neurodegenerative diseases. These include amyotrophic lateral sclerosis (Charcot's disease), disease of "mad cow and other prion diseases. dextromethorphan has also been used for the treatment of mental retardation, Parkinson's disease, in the treatment of lung and other cancers and to prevent tissue rejection in transplantation because of the (poorly known) effects of sigma ligands on tumor cells and immune system.

Pharmacokinetics

After oral administration dextromethorphan is completely absorbed from the gastrointestinal tract. Cmax of dextromethorphan in plasma is reached after 2 h. This medication biotransformes in the liver. Up to 45% of this drug is excreted by kidneys and there was considerable individual variation in rates of excretion of individual metabolites.

Why is dextromethorphan prescribed?

Dry cough of different etiology.

Dosage and administration

For adults and children over 12 years dextromethorphan prescribed on 15 mg 4 times / day, children aged 6 years - 7.5 mg 4 times / day.

dextromethorphan side effects, adverse reactions

Drowsiness, nausea, dizziness.

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dextromethorphan contraindications

Bronchial asthma, bronchitis, simultaneous reception of mucolytic.

Using during pregnancy and breastfeeding

During pregnancy and lactation (breastfeeding) dextromethorphan prescribed with caution, only in cases where the expected therapeutic effect for the mother outweighs the potential risk to the fetus or child.

Special instructions

With carefully administered dextromethorphan with impaired liver function.

dextromethorphan drug interactions

MAO inhibitors when administered simultaneous with dextromethorphan may cause adrenergic crisis, collapse, coma, dizziness, agitation, increased blood pressure, hyperpyrexia, intracranial hemorrhage, lethargy, nausea, cramps, tremor. In combination with tricyclic antidepressants (amitriptyline, etc.) dextromethorphan may appeal serotonin syndrome and possible subsequent death. Amiodarone, fluoxetine, quinidine, inhibiting system cytochrome P450, may increase the drug concentration in the blood. Tobacco smoke can lead to increased secretion of glands in the background of inhibition of cough reflex. Some inhibitors of CYP450 (such as quinidine) increase and extended effects of this medicine.

dextromethorphan in case of emergency / overdose

Symptoms: excitement, dizziness, respiratory depression, impaired consciousness, decreased blood pressure, tachycardia, muscle hypertonicity, ataxia.

Treatment: mechanical ventilation, symptomatic agents.

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Dextromethorphan available forms, composition, doses:

Price
Adlt robitussin cough-cold-flu0.04 USD
Adt robitussin cough-cold d lq0.04 USD
Adult robitussin cough syrup0.04 USD
Apap allergy sinus caplet0.05 USD
Childrens triaminic decon spray0.24 USD
Delsym 30 mg/5 ml suspension0.11 USD
Dextromethorphan hbr cryst2.06 USD
Dextromethorphan hbr powder4.74 USD
Dextromethorphan powder14.93 USD
Guaifenesin dm syrup0.02 USD
Hca severe cough stopper cplet0.23 USD
Hold 4 hour lozenge regular0.24 USD
Linctus; Oral; Dextromethorphan Hydrobromide 15 mg / ml
Modicon (28) 28 0.5-35 mg-mcg tablet Disp Pack59.99 USD
Robitussin chest congest syrup0.04 USD
Robitussin cough & cold liquid0.04 USD
Robitussin cough-cold liquid0.04 USD
Robitussin cough-cong syrup0.04 USD
Robitussin coughgels0.25 USD
Robitussin dm max liquid0.04 USD
Robitussin dm to go liquid0.09 USD
Robitussin long-acting liq0.04 USD
Robitussin pe head & chest liq0.04 USD
Robitussin-cough-chest-cong lq0.04 USD
Robitussin-dm cough syrup0.04 USD
Suspension, Extended Release; Oral; Dextromethorphan Polistirex 30 mg / 5 ml
Syrup; Oral; Dextromethorphan Hydrobromide 10 mg / 5 ml
Tablets; Oral; Dextromethorphan Hydrobromide 15 mg
Triaminic allergy thin strip0.35 USD
Triaminic cgh-runny nose strip0.3 USD
Triaminic chest-nasal cong liq0.04 USD
Triaminic cold & cough liquid0.04 USD
Triaminic cold-allergy pe liq0.04 USD
Triaminic cold-stuff nose strip0.35 USD
Triaminic cough strips0.3 USD
Triaminic cough-cold chew0.27 USD
Triaminic cough-nasal cong liq0.04 USD
Triaminic cough-sore throat lq0.04 USD
Triaminic flu cough-fever susp0.04 USD
Triaminic flu-cough-fever liq0.04 USD
Triaminic softchew tablet0.27 USD
Triaminic softchews tablet0.25 USD
Triaminic-d syrup0.04 USD
Triaminicin tablet0.23 USD
Vicks 44 cough liquid0.03 USD
Vicks 44 custom care liquid0.03 USD

Indications and Usages:

ATC codes:


ICD-10 codes:


Dextromethorphan destination | category:


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Drugs with same active ingredients (Pharmaceutical companies):


References

  1. Dailymed."MIELIM Y MAS (DEXTROMETHORPHAN) LIQUID [EFFICIENT LABORATORIES INC.]". https://dailymed.nlm.nih.gov/dailym... (accessed August 28, 2018).
  2. Dailymed."DEXTROMETHORPHAN HYDROBROMIDE: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailym... (accessed August 28, 2018).
  3. "dextromethorphan". https://pubchem.ncbi.nlm.nih.gov/co... (accessed August 28, 2018).

Frequently asked Questions

Can i drive or operate heavy machine after consuming Dextromethorphan?

Depending on the reaction of the Dextromethorphan after taken, if you are feeling dizziness, drowsiness or any weakness as a reaction on your body, Then consider Dextromethorphan not safe to drive or operate heavy machine after consumption. Meaning that, do not drive or operate heavy duty machines after taking the capsule if the capsule has a strange reaction on your body like dizziness, drowsiness. As prescribed by a pharmacist, it is dangerous to take alcohol while taking medicines as it exposed patients to drowsiness and health risk. Please take note of such effect most especially when taking Primosa capsule. It's advisable to consult your doctor on time for a proper recommendation and medical consultations.

Is Dextromethorphan addictive or habit forming?

Medicines are not designed with the mind of creating an addiction or abuse on the health of the users. Addictive Medicine is categorically called Controlled substances by the government. For instance, Schedule H or X in India and schedule II-V in the US are controlled substances.

Please consult the medicine instruction manual on how to use and ensure it is not a controlled substance.In conclusion, self medication is a killer to your health. Consult your doctor for a proper prescription, recommendation, and guidiance.

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Review

sdrugs.com conducted a study on Dextromethorphan, and the result of the survey is set out below. It is noteworthy that the product of the survey is based on the perception and impressions of the visitors of the website as well as the views of Dextromethorphan consumers. We, as a result of this, advice that you do not base your therapeutic or medical decisions on this result, but rather consult your certified medical experts for their recommendations.

Visitor reports

Visitor reported useful

No survey data has been collected yet

Visitor reported side effects

No survey data has been collected yet

Visitor reported price estimates

No survey data has been collected yet

Visitor reported frequency of use

No survey data has been collected yet

One visitor reported doses

What is the dose of Dextromethorphan drug you are taking?
According to the survey conducted among sdrugs.com website users, the maximum number of people are using the following dose 11-50mg. Few medications come in only one or two doses. Few are specific for adult dose and child dose. The dose of the medicine given to the patient depends on the severity of the symptom/disease. There can be dose adjustments made by the doctor, based on the progression of the disease. Follow-up is important.
Visitors%
11-50mg1
100.0%

Visitor reported time for results

No survey data has been collected yet

Visitor reported administration

No survey data has been collected yet

Two visitors reported age

Visitors%
> 601
50.0%
6-151
50.0%

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The information was verified by Dr. Arunabha Ray, MD Pharmacology

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