Active ingredient: Clotrimazole

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When are you taking this medicine?

Clotrimazole uses


Pharmacological action

Clotrimazole is an antifungal agent of imidazole derivatives group for topical use. This medication has an effect at the expense of the synthesis of ergosterol, which is part of the cell membrane of fungi. Clotrimazole has a broad spectrum of action.

Clotrimazole is active against dermatophytes, molds, fungi of the genus Candida, Malassezia furfur.

This drug is also active against Corynebacterium minutissimum, Streptococcus spp., Staphylococcus spp., Trichomonas vaginalis.

Pharmacokinetics

For external use Clotrimazole is well into the various layers of the skin reaching therapeutic concentrations. When this medication applied topically a small amount of it absorbed into the bloodstream.

Why is Clotrimazole prescribed?

Fungal skin and mucous membranes: ringworm, tinea, trichophytosis, athlete, mikrosporiya, candidiasis, a fungal interdigital erosion, fungal paronychia; fungal infections complicated by a secondary pyoderma; colorful lichen, erythrasma; thrush; Candida vulvitis, vulvovaginitis, balanitis, trichomoniasis; for the renovation of the birth canal before delivery.

Dosage and administration

When Clotrimazole used externally it applied to affected skin 2-3 times / day in 2-4 weeks.

For local orally this medicine used 1-2 times / day, no more than 7 days.

Intravaginal - on 100-500 mg for 1-6 days.

Clotrimazole side effects, adverse reactions

Local reactions: contact allergic dermatitis, redness, burning sensation.

When applied topically to the skin: erythema, blisters, swelling, burning and tingling, irritation and flaking skin.

When applied topically for the treatment of urogenital infections: itching, burning, redness and swelling of the mucous membrane, vaginal discharge, frequent urination, intercurrent cystitis, burning sensation in the penis with a partner, pain during sexual intercourse.

When applied topically in the oral cavity: redness of the oral mucosa, burning sensation and tingling at the site of application, irritation.

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Clotrimazole contraindications

Hypersensitivity to Clotrimazole, I trimester of pregnancy.

Using during pregnancy and breastfeeding

In experimental studies there have been found that Clotrimazole used in high doses exerts embryotoxic effect.

It is not known whether Clotrimazole released in breast milk. Although Clotrimazole is not contraindicated during pregnancy and lactation, it should be considered a potential risk when selecting antifungal therapy.

Special instructions

Prescribed intravaginal Dosage forms of Clotrimazole is not used during menstruation.

To prevent reinfection it should be simultaneous treatment of sexual partners.

Clotrimazole is not recommended for use in ophthalmology.

Clotrimazole drug interactions

Simultaneous administration of Clotrimazole with amphotericin B, nystatin, natamycin activity of Clotrimazole decreases.

Clotrimazole in case of emergency / overdose

Symptoms: anorexia, nausea, vomiting, stomachodynia, abnormal liver function, rarely - drowsiness, hallucinations, thamuria, allergic skin reactions.

Treatment: taking activated charcoal, symptomatic therapy.

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Clotrimazole available forms, composition, doses:

Price
Antifungal 1% cream0.27 USD
CVS Pharmacy clotrimazole 1% cream0.32 USD
Clotrim 1% vaginal cream0.18 USD
Clotrimazole 1% Cream 15 gm Tube17.99 USD
Clotrimazole 1% Cream 30 gm Tube35.99 USD
Clotrimazole 1% Cream 45 gm Tube49.99 USD
Clotrimazole 1% Solution 10ml Bottle17.99 USD
Clotrimazole 1% Solution 30ml Bottle24.99 USD
Clotrimazole 1% cream0.53 USD
Clotrimazole 10 mg troche1.61 USD
Clotrimazole 3 2% cream0.5 USD
Clotrimazole 70 10 mg Troche Bottle117.04 USD
Clotrimazole insert0.86 USD
Clotrimazole powder5.2 USD
Cream; Topical; Clotrimazole 1%
Cream; Topical; Clotrimazole 2%
Cream; Topical; Vaginal; Clotrimazole 1%
Cream; Vaginal; Clotrimazole 1%
Desenex 1% cream0.33 USD
Gyne-lotrimin insert1.03 USD
Lotrimin 1% cream1.28 USD
Lotrimin af 2% liquid spray0.04 USD
Lotrimin af 2% spray powder0.05 USD
Lotrimin ultra 1% cream0.68 USD
Mycelex 1% cream0.9 USD
Mycelex 10 mg troche1.85 USD
Mycelex-7 100 mg vaginal tablet1.33 USD
Ointment; Topical; Clotrimazole 1%
Ra athlete's 1% foot cream0.37 USD
Ra clotrimazole 3 cream0.46 USD
Ra clotrimazole af cream0.24 USD
Sm antifungal 1% cream0.25 USD
Solution; Topical; Clotrimazole 1%
Tablets; Vaginal; Clotrimazole 100 mg
Tablets; Vaginal; Clotrimazole 200 mg
Tablets; Vaginal; Clotrimazole 500 mg
Troche / Lozenges; Oral; Clotrimazole 10 mg

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Indications and Usages:

ATC codes:


ICD-10 codes:


Clotrimazole destination | category:



Drugs with same active ingredients (Pharmaceutical companies):


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References

  1. Dailymed."GYNE-LOTRIMIN 3 (CLOTRIMAZOLE) CREAM [MSD CONSUMER CARE, INC.]". https://dailymed.nlm.nih.gov/dailym... (accessed August 28, 2018).
  2. Dailymed."BETAMETHASONE DIPROPIONATE; CLOTRIMAZOLE: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailym... (accessed August 28, 2018).
  3. "clotrimazole". https://pubchem.ncbi.nlm.nih.gov/co... (accessed August 28, 2018).

Frequently asked Questions

Can i drive or operate heavy machine after consuming Clotrimazole?

Depending on the reaction of the Clotrimazole after taken, if you are feeling dizziness, drowsiness or any weakness as a reaction on your body, Then consider Clotrimazole not safe to drive or operate heavy machine after consumption. Meaning that, do not drive or operate heavy duty machines after taking the capsule if the capsule has a strange reaction on your body like dizziness, drowsiness. As prescribed by a pharmacist, it is dangerous to take alcohol while taking medicines as it exposed patients to drowsiness and health risk. Please take note of such effect most especially when taking Primosa capsule. It's advisable to consult your doctor on time for a proper recommendation and medical consultations.

Is Clotrimazole addictive or habit forming?

Medicines are not designed with the mind of creating an addiction or abuse on the health of the users. Addictive Medicine is categorically called Controlled substances by the government. For instance, Schedule H or X in India and schedule II-V in the US are controlled substances.

Please consult the medicine instruction manual on how to use and ensure it is not a controlled substance.In conclusion, self medication is a killer to your health. Consult your doctor for a proper prescription, recommendation, and guidiance.

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Review

sdrugs.com conducted a study on Clotrimazole, and the result of the survey is set out below. It is noteworthy that the product of the survey is based on the perception and impressions of the visitors of the website as well as the views of Clotrimazole consumers. We, as a result of this, advice that you do not base your therapeutic or medical decisions on this result, but rather consult your certified medical experts for their recommendations.

Visitor reports

Visitor reported useful

No survey data has been collected yet

Visitor reported side effects

No survey data has been collected yet

Visitor reported price estimates

No survey data has been collected yet

One visitor reported frequency of use

How often in a day do you take the medicine?
Are you taking the Clotrimazole drug as prescribed by the doctor?

Few medications can be taken Twice in a day more than prescribed when the doctor's advice mentions the medicine can be taken according to frequency or severity of symptoms. Most times, be very careful and clear about the number of times you are taking the medication. The report of sdrugs.com website users about the frequency of taking the drug Clotrimazole is mentioned below.
Visitors%
Twice in a day1
100.0%

Five visitors reported doses

What is the dose of Clotrimazole drug you are taking?
According to the survey conducted among sdrugs.com website users, the maximum number of people are using the following dose 6-10mg. Few medications come in only one or two doses. Few are specific for adult dose and child dose. The dose of the medicine given to the patient depends on the severity of the symptom/disease. There can be dose adjustments made by the doctor, based on the progression of the disease. Follow-up is important.
Visitors%
6-10mg2
40.0%
1-5mg2
40.0%
201-500mg1
20.0%

Two visitors reported time for results

What is the time duration Clotrimazole drug must be taken for it to be effective or for it to reduce the symptoms?
Most chronic conditions need at least some time so the dose and the drug action gets adjusted to the body to get the desired effect. The stastistics say sdrugs.com website users needed 1 week to notice the result from using Clotrimazole drug. The time needed to show improvement in health condition after using the medicine Clotrimazole need not be same for all the users. It varies based on other factors.
Visitors%
1 week1
50.0%
2 days1
50.0%

Visitor reported administration

No survey data has been collected yet

Two visitors reported age

Visitors%
46-602
100.0%

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The information was verified by Dr. Arunabha Ray, MD Pharmacology

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