DRUGS & SUPPLEMENTS
How long you have been taking the medicine?
ciprofloxacin is a broad-spectrum antimicrobial drug of fluoroquinolone group with bactericidal action. Inhibits DNA gyrase and inhibits the synthesis of bacterial DNA. Highly active against most gram-negative bacteria: Pseudomonas aeruginosa, Haemophilus influenzae, Escherichia coli, Shigella spp., Salmonella spp., Neisseria meningitidis, Neisseria gonorrhoeae.
ciprofloxacin is active against Staphylococcus spp., some strains of Enterococcus spp., Campylobacter spp., Legionella spp., Mycoplasma spp., Chlamydia spp., Mycobacterium spp.
ciprofloxacin is active against bacteria producing beta-lactamases.
Ureaplasma urealyticum, Clostridium difficile, Nocardia asteroides resistant to ciprofloxacin. The effect on Treponema pallidum is studied not enough.
ciprofloxacin rapidly absorbed from the gastrointestinal tract. Bioavailability after oral administration of 70%. Eating has a little effect on the absorption of ciprofloxacin. Plasma protein binding is 20-40%. Distributed in tissues and body fluids. It penetrates the cerebrospinal fluid: the concentration of ciprofloxacin for not inflamed meninges reach 10% with inflammation - up to 37%. High concentrations are achieved in bile. Excreted in the urine and bile.
Infectious-inflammatory diseases caused by microorganisms susceptible to ciprofloxacin, including respiratory diseases, diseases of abdominal and pelvic organs, bones, joints, skin, septicemia; severe infections of ENT organs. Treatment of postoperative infections. Prevention and treatment of infections in patients with reduced immunity.
For ciprofloxacin local use: acute and subacute conjunctivitis, blepharoconjunctivitis, blepharitis, bacterial corneal ulcers, keratitis, keratoconjunctivitis, chronic dacryocystitis, meybomity. Infectious lesions in the eyes from injury or contact with foreign bodies. Preoperative prophylaxis in ophthalmic surgery.
Individual. For oral administration dose of ciprofloxacin is 250-750 mg 2 times / day. Treatment duration is from 7-10 days to 4 weeks.
For IV administration a single dose is 200-400 mg, the multiplicity of the introduction is 2 times / day, duration of treatment - 1-2 weeks and more if necessary. May be IV injected as jet but more preferably a drip for 30 minutes.
When ciprofloxacin applied topically instilled 1-2 drops into the lower conjunctival sac of the affected eye every 1-4 hours. After improving the intervals between instillation can be increased. The maximum oral daily dose for adults is 1.5 g.
Digestive system: nausea, vomiting, diarrhea, abdominal pain, increase in liver transaminases, alkaline phosphatase, LDH, bilirubin, pseudomembranous colitis.
CNS: headache, dizziness, fatigue, insomnia, nightmares, hallucinations, fainting, disorders of vision.
Urinary system: crystalluria, glomerulonephritis, dysuria, polyuria, albuminuria, hematuria, transient increase of serum creatinine.
Hemopoietic system: eosinophilia, leukopenia, neutropenia, changes in the number of platelets.
Cardiovascular system: tachycardia, cardiac arrhythmias, hypotension.
Allergic reactions: itching, urticaria, Quincke's edema, Stevens-Johnson syndrome, arthralgia.
Adverse reactions associated with the chemotherapeutic effect: candidiasis.
Local reactions: pain, phlebitis. When applying eye drops in some cases may be mild pain and conjunctival hyperemia.
Pregnancy, lactation (breastfeeding), childhood and adolescence to 15 years, increased sensitivity to ciprofloxacin and other drugs hinolonovogo series; deficiency of glucose-6-phosphate dehydrogenase; in ophthalmology: viral keratitis.
Pronounced cerebral arteriosclerosis, cerebral circulatory disorder, mental illness, epilepsy, epileptic syndrome, marked renal and / or hepatic insufficiency.
Contraindicated in pregnancy ; ciprofloxacin crosses the placenta, excreted in breast milk.
In experimental studies found that it causes arthropathy. In experiments on rats and mice treated with ciprofloxacin in doses exceeding the usual daily dose for a person 6 times, adverse effects on the fetus is not revealed. In experiments on rabbits treated with oral dose of ciprofloxacin 30 and 100 mg / kg, it is shown that the drug causes disruption of the gastrointestinal tract, leading to loss of body weight in females and increase the number of miscarriages but teratogenicity not found. When IV introduction to the doses of 20 mg / kg ciprofloxacin did not exert toxic effects on the mother and embryo, showed no teratogenicity. The use of local forms of ciprofloxacin in pregnancy is possible if the anticipated benefits exceed the potential risk to the fetus.
Category of the fetus by FDA - C.
ciprofloxacin is excreted in breast milk, so the period of lactation should decide, stop taking ciprofloxacin or breastfeeding based on the degree of importance of the use of drugs for the mother.
With careful use of local forms of ciprofloxacin in breast-feeding (not known whether ciprofloxacin is excreted in breast milk when applied topically).
Patients with impaired renal function requires correction dosing regimen. With caution used in elderly patients, with cerebral arteriosclerosis, cerebral circulatory disorders, epilepsy, convulsive syndrome of unknown etiology.
During treatment patients with ciprofloxacin should receive enough amounts of liquids.
In the case of persistent diarrhea ciprofloxacin should not be taken.
At the same time of ciprofloxacin IV introduction and barbiturates is necessary to monitor heart rate, blood pressure, ECG. In the course of treatment is necessary to monitor blood concentrations of urea, creatinine, hepatic transaminases.
In the period of treatment may decrease the reactivity (especially when used with alcohol).
Not allowed the introduction of ciprofloxacin subconjunctival or directly into the anterior chamber of the eye.
Due to the threat of adverse reactions from the CNS ciprofloxacin should be used only according to the life in the pathology of the CNS in history: organic brain lesions, epilepsy, lowering the convulsive threshold, severe atherosclerosis of the brain, the elderly, with severely impaired renal function and liver (requires monitoring concentrations in blood plasma).
Patients with allergic reactions to fluoroquinolone derivatives in history may develop reactions to ciprofloxacin. During the period of treatment should avoid sunlight and UV radiation, intense physical exercise, control of drinking mode, pH of urine.
Reported cases of crystalluria, particularly in patients with alkaline reaction of urine (pH 7 or more). In order to avoid the development of crystalluria unacceptable excess of the recommended daily dose, should also be adequate fluid intake and maintaining acidic urine.
If you have pain in the tendons or the first signs tendovaginitah treatment should be discontinued (described isolated cases of inflammation or tendon rupture during fluoroquinolone treatment).
It can reduce the speed of psychomotor reactions, especially against the backdrop of alcohol, that should be considered for patients who work with potentially dangerous machinery or drive vehicles.
If you have severe diarrhea, pseudomembranous colitis should be excluded (for which ciprofloxacin is contraindicated). At the same time of barbiturates IV injections requires monitoring function of the cardiovascular system (heart rate, BP, ECG). Teenagers under 18 years shall be appointed only if the pathogen resistance to other chemotherapeutic drugs. The solution in the form of eye drops are not designed for intraocular injections. The use of other ophthalmic means the interval between injections should be at least 5 minutes.
Activity increases when combined with beta-lactam antibiotics, aminoglycosides, vancomycin, clindamycin, metronidazole. Sukralfat, bismuth preparations, antacids containing aluminum ions, magnesium or calcium, cimetidine, ranitidine, vitamin and mineral supplement, iron sulfate, zinc, didanosine (recommended for 2 hours before or 4 hours after these drugs) reduce the suction. Probenecid, azlocillin increase the concentration in the blood. Decreases clearance and increases in plasma caffeine, aminophylline and theophylline (increased likelihood of side effects). ciprofloxacin enhances the effect of warfarin and other oral anticoagulants (prolongs bleeding time). Increases nephrotoxicity of cyclosporine, increase the risk of CNS excitability and convulsive reactions against the background of NSAIDs. Medicines alkalinizing the urine (citrates, sodium bicarbonate, carbonic anhydrase inhibitors) reduce the solubility (increases the probability of crystalluria). Infusion solutions of ciprofloxacin ready to use can be combined with infusion solutions: 0.9% sodium chloride solution, Ringer's solution, Ringer lactate, 5 and 10% dextrose, 10% solution of fructose, and a solution containing 5% dextrose with 0,225 or 0.45% sodium chloride. Incompatible with solutions having a pH > 7.
May occur after receiving a single large dose or prolonged use. If a single dose of less than 150 mg / kg, acute poisoning feel light, 150-300 mg / kg - moderate, when using higher doses - heavy.
Symptoms: No specific symptoms.
Treatment: gastric lavage, the use of emetic drugs, the introduction of large quantities of liquid, the creation of acidic urine, in addition - hemodialysis and peritoneal dialysis (can be derived only 10% of the drug), all events are held on the background to maintain vital functions. The specific antidote is unknown.
|Apo-Ciproflox 0.3 % Solution||1.18 USD|
|Cetraxal 0.2% ear solution||7.14 USD|
|Ciloxan 0.3 % Solution||2.18 USD|
|Ciloxan 0.3% Ointment 3.5 gm Tube||87.49 USD|
|Ciloxan 0.3% Solution 5ml Bottle||68.33 USD|
|Ciloxan 0.3% eye drops||13.33 USD|
|Cipro 250 mg tablet||5.2 USD|
|Cipro 250 mg/5ml(5%) Suspension 100ml Bottle||116.8 USD|
|Cipro 400 mg Solution 40ml Vial||259.99 USD|
|Cipro 500 mg tablet||6.08 USD|
|Cipro 500 mg/5ml(10%) Suspension 100ml Bottle||136.75 USD|
|Cipro 750 mg tablet||6.26 USD|
|Cipro HC 0.2-1% Suspension 10ml Bottle||131.54 USD|
|Cipro XR 1000 mg 24 Hour tablet||10.75 USD|
|Cipro XR 500 mg 24 Hour tablet||10.88 USD|
|Cipro hc otic suspension||12.65 USD|
|Cipro i.v. 10 mg/ml vial||0.72 USD|
|Cipro i.v. 200 mg/100 ml d5w||0.16 USD|
|Cipro xr 1000 mg tablet||11.91 USD|
|Cipro xr 500 mg tablet||10.46 USD|
|Ciprofloxacin 0.3% eye drop||12.96 USD|
|Ciprofloxacin 200 mg/20 ml vial||0.13 USD|
|Ciprofloxacin HCl 0.3% Solution 10ml Bottle||98.22 USD|
|Ciprofloxacin HCl 0.3% Solution 2.5ml Bottle||26.03 USD|
|Ciprofloxacin HCl 0.3% Solution 5ml Bottle||49.2 USD|
|Ciprofloxacin er 1000 mg tablet||11.16 USD|
|Ciprofloxacin er 500 mg tablet||9.8 USD|
|Ciprofloxacin hcl 100 mg tablet||4.17 USD|
|Ciprofloxacin hcl 250 mg tablet||4.59 USD|
|Ciprofloxacin hcl 500 mg tablet||5.59 USD|
|Ciprofloxacin hcl 750 mg tablet||5.65 USD|
|Ciprofloxacin hcl powder||1.29 USD|
|Ciprofloxacin-Ciproflox HCl 1000 mg 24 Hour tablet||11.6 USD|
|Ciprofloxacin-Ciproflox HCl 500 mg 24 Hour tablet||10.19 USD|
|Ciprofloxacn-d5w 200 mg/100 ml||0.03 USD|
|Drops; Ophthalmic, Otic; Ciprofloxacin Hydrochloride Monohydrate 0.3%|
|Drops; Ophthalmic; Ciprofloxacin 0.3%|
|Drops; Ophthalmic; Ciprofloxacin Hydrochloride 0.3%|
|Drops; Otic; Ciprofloxacin 0.3%|
|Floxin 200 mg tablet||6.6 USD|
|Floxin 300 mg tablet||5.61 USD|
|Floxin 400 mg tablet||9.55 USD|
|Floxin Otic 0.3% Solution 10ml Bottle||142.91 USD|
|Floxin Otic 0.3% Solution 5ml Bottle||86.49 USD|
|Floxin otic singles||4.28 USD|
|Injectable; Infusion; Ciprofloxacin 2 mg / ml|
|Injectable; Infusion; Ciprofloxacin Lactate 2 mg / ml|
|Injectable; Injection; Ciprofloxacin 10 mg / ml|
|Injectable; Injection; Ciprofloxacin 2 mg / ml|
|Injectable; Injection; Ciprofloxacin 2 mg; Sodium Chloride 9 mg|
|Injectable; Injection; Ciprofloxacin Hydrochloride 10 mg / ml|
|Injectable; Injection; Ciprofloxacin Hydrochloride 2 mg / ml|
|Injectable; Injection; Ciprofloxacin Lactate 10 mg / ml|
|Injectable; Injection; Ciprofloxacin Lactate 2 mg / ml|
|Ocuflox 0.3% Solution 10ml Bottle||106.09 USD|
|Ocuflox 0.3% Solution 5ml Bottle||57.32 USD|
|Ocuflox 0.3% eye drops||11.35 USD|
|Pms-Ciprofloxacin 0.3 % Solution||1.18 USD|
|ProQuin XR 3 500 mg 24 Hour tablet Disp Pack||39.99 USD|
|ProQuin XR 500 mg 24 Hour tablet||11.18 USD|
|Proquin xr 500 mg tablet||12.18 USD|
|Solution; Ophthalmic; Ciprofloxacin 0.3%|
|Solution; Ophthalmic; Ciprofloxacin Hydrochloride 0.3%|
|Tablets, Extended Release; Oral; Ciprofloxacin Hydrochloride 1000 mg|
|Tablets, Extended Release; Oral; Ciprofloxacin Hydrochloride 500 mg|
|Tablets, Film-Coated; Oral; Ciprofloxacin 100 mg|
|Tablets, Film-Coated; Oral; Ciprofloxacin 250 mg|
|Tablets, Film-Coated; Oral; Ciprofloxacin 500 mg|
|Tablets, Film-Coated; Oral; Ciprofloxacin 750 mg|
|Tablets, Film-Coated; Oral; Ciprofloxacin Hydrochloride 250 mg|
|Tablets, Film-Coated; Oral; Ciprofloxacin Hydrochloride 500 mg|
|Tablets, Film-Coated; Oral; Ciprofloxacin Hydrochloride 750 mg|
|Tablets; Oral; Ciprofloxacin 250 mg|
|Tablets; Oral; Ciprofloxacin 500 mg|
|Tablets; Oral; Ciprofloxacin 750 mg|
|Tablets; Oral; Ciprofloxacin Hydrochloride 100 mg|
|Tablets; Oral; Ciprofloxacin Hydrochloride 250 mg|
|Tablets; Oral; Ciprofloxacin Hydrochloride 500 mg|
|Tablets; Oral; Ciprofloxacin Hydrochloride 750 mg|
Depending on the reaction of the Ciprofloxacin after taken, if you are feeling dizziness, drowsiness or any weakness as a reaction on your body, Then consider Ciprofloxacin not safe to drive or operate heavy machine after consumption. Meaning that, do not drive or operate heavy duty machines after taking the capsule if the capsule has a strange reaction on your body like dizziness, drowsiness. As prescribed by a pharmacist, it is dangerous to take alcohol while taking medicines as it exposed patients to drowsiness and health risk. Please take note of such effect most especially when taking Primosa capsule. It's advisable to consult your doctor on time for a proper recommendation and medical consultations.Is Ciprofloxacin addictive or habit forming?
Medicines are not designed with the mind of creating an addiction or abuse on the health of the users. Addictive Medicine is categorically called Controlled substances by the government. For instance, Schedule H or X in India and schedule II-V in the US are controlled substances.
Please consult the medicine instruction manual on how to use and ensure it is not a controlled substance.In conclusion, self medication is a killer to your health. Consult your doctor for a proper prescription, recommendation, and guidiance.
|Once in a day||1||100.0%|
|With a meal||1||50.0%|
There are no reviews yet. Be the first to write one!
The information was verified by Dr. Rachana Salvi, MD Pharmacology