Siprofen - Pharmacological action NSAIDs, a derivative of phenylpropionic acid, ibuprofen has anti-inflammatory, analgesic and antipyretic effect. The mechanism of action is associated with inhibition of COX activity - the main enzyme metabolism of arachidonic acid, which is a precursor of prostaglandins, which play a major role in the pathogenesis of inflammation, pain and fever. Analgesic effect is due to both peripheral (indirectly, through suppression of prostaglandin synthesis), and a central...