Pharma company: hikma pharmaceuticals

List of hikma pharmaceuticals products:

• Amiodarone - An antianginal and antiarrhythmic drug. It increases the duration of ventricular and atrial muscle action by inhibiting Na,K-activated myocardial adenosine triphosphatase. There is a resulting decrease in heart rate and in vascular resistance. [PubChem] Indication: Intravenously, for initiation of treatment and prophylaxis of frequently recurring ventricular fibrillation and hemodynamically unstable ventricular tachycardia in patients refractory to other therapy. Orally, for the treatment of...
• Amlodipine - Amlodipine is a long-acting 1,4-dihydropyridine calcium channel blocker. It acts primarily on vascular smooth muscle cells by stabilizing voltage-gated L-type calcium channels in their inactive conformation. By inhibiting the influx of calcium in smooth muscle cells, amlodipine prevents calcium-dependent myocyte contraction and vasoconstriction. A second proposed mechanism for the drug’s vasodilatory effects involves pH-dependent inhibition of calcium influx via inhibition of smooth...
• Amoxicillin - 1.1 Infections of the Ear, Nose, and Throat Amoxicillin tablets are indicated in the treatment of infections due to susceptible (ONLY β-lactamase-negative) isolates of Streptococcus species. (α- and β-hemolytic isolates only), Streptococcus pneumoniae, Staphylococcus spp., or Haemophilus influenzae. 1.2 Infections of the Genitourinary Tract Amoxicillin tablets are indicated in the treatment of infections due to susceptible (ONLY...
• Amoxicillin; Clavulanate
• Argatroban - Dosing and Administration, Dosing in Patients Undergoing Percutaneous Coronary Intervention ( 2.2 ) 5/2016 1 INDICATIONS AND USAGE Argatroban Injection is a direct thrombin inhibitor indicated: • For prophylaxis or treatment of thrombosis in adult patients...
• Benztropine
• Butorphanol - A synthetic morphinan analgesic with narcotic antagonist action. It is used in the management of severe pain. [PubChem] Indication: For the relief of moderate to severe pain. Butorphanol is a synthetic opioid agonist-antagonist analgesic with a pharmacological and therapeutic profile that has been well established since its launch as a parenteral formulation in 1978. The introduction of a transnasal formulation of butorphanol represents a new and noninvasive presentation of an analgesic for...
• Carvedilol - Carvedilol information Carvedilol is a blood pressure medication and belongs to the class of drugs known as beta-blockers. These beta-blockers affect the circulatory system, which includes the human heart, arteries and veins. Carvedilol indications This medication is used primarily in treating hypertension or high blood pressure. Carvedilol warnings Taking Carvedilol may not be advisable if you have any of the following conditions: asthma heart problems such as low blood pressure...
• Cedrox
• Cefaclor - SPL UNCLASSIFIED SECTION CEFACLOR CAPSULES, USP Rev. 09/15 Rx Only To reduce the development of drug-resistant bacteria and maintain the effectiveness of cefaclor and other antibacterial drugs, cefaclor should be used only to treat or prevent infections that are proven or strongly suspected to be caused by bacteria. DESCRIPTION ...
• Cefamezin
• Cefazolin - SPL UNCLASSIFIED SECTION To reduce the development of drug-resistant bacteria and maintain the effectiveness of Cefazolin for Injection and other antibacterial drugs, Cefazolin for Injection should be used only to treat or prevent infections that are proven or strongly suspected to be caused by bacteria. DESCRIPTION Cefazolin for Injection, USP is a semi-synthetic cephalosporin for parenteral...
• Cefizox
• Ceflax
• Cefofix
• Cefotaxime - SPL UNCLASSIFIED SECTION Rx ONLY PHARMACY BULK PACKAGE – NOT FOR DIRECT INFUSION   To reduce the development of drug-resistant bacteria and maintain the effectiveness of Cefotaxime for Injection, USP...
• Cefoxitin - SPL UNCLASSIFIED SECTION PHARMACY BULK PACKAGE NOT FOR DIRECT INFUSION Rx Only To reduce the development of drug-resistant bacteria and maintain the effectiveness...
• Ceftax
• Ceftriaxone - SPL UNCLASSIFIED SECTION Rx only To reduce the development of drug-resistant bacteria and maintain the effectiveness of Ceftriaxone for Injection, USP and other antibacterial drugs, Ceftriaxone for Injection, USP should be used only to treat or prevent infections that are proven or strongly suspected to be caused by bacteria. DESCRIPTION ...
• Cefuroxime - PHARMACY BULK PACKAGE NOT FOR DIRECT INFUSION Rx only To reduce the development of drug-resistant bacteria and maintain the effectiveness of Cefuroxime for Injection, USP and other antibacterial drugs, Cefuroxime for Injection, USP should be used only to treat or...
• Cephalexin - 1 INDICATIONS & USAGE Cephalexin is a cephalosporin antibacterial drug indicated for the treatment of the following infections caused by susceptible isolates of designated bacteria: Respiratory tract infection ( 1.1 ) Otitis media ( 1.2 ) ...
• Ciproflaxin - Pharmacological action Ciprofloxacin is a broad-spectrum antimicrobial drug of fluoroquinolone group with bactericidal action. Inhibits DNA gyrase and inhibits the synthesis of bacterial DNA. Highly active against most gram-negative bacteria: Pseudomonas aeruginosa, Haemophilus influenzae, Escherichia coli, Shigella spp., Salmonella spp., Neisseria meningitidis, Neisseria gonorrhoeae. Ciprofloxacin is active against Staphylococcus spp. (including strains producing and not producing...
• Ciprofloxacin - Chemical Structure WARNING Fluoroquinolones, including Ciprofloxacin Tablets, are associated with an increased risk of tendinitis and tendon rupture in all ages. This risk is further increased in older patients usually over 60 years of age, in patients taking corticosteroid drugs, and in patients with kidney, heart or lung transplants (See WARNINGS ). ...
• Ciprofloxacin in Dextrose - Pharmacological action Ciprofloxacin is a broad-spectrum antimicrobial drug of fluoroquinolone group with bactericidal action. Inhibits DNA gyrase and inhibits the synthesis of bacterial DNA. Highly active against most gram-negative bacteria: Pseudomonas aeruginosa, Haemophilus influenzae, Escherichia coli, Shigella spp., Salmonella spp., Neisseria meningitidis, Neisseria gonorrhoeae. Ciprofloxacin is active against Staphylococcus spp. (including strains producing and not producing...
• Ciprofloxacin in Dextrose 5% in plastic container - Pharmacological action Ciprofloxacin is a broad-spectrum antimicrobial drug of fluoroquinolone group with bactericidal action. Inhibits DNA gyrase and inhibits the synthesis of bacterial DNA. Highly active against most gram-negative bacteria: Pseudomonas aeruginosa, Haemophilus influenzae, Escherichia coli, Shigella spp., Salmonella spp., Neisseria meningitidis, Neisseria gonorrhoeae. Ciprofloxacin is active against Staphylococcus spp. (including strains producing and not producing...
• Clonidine - Clonidine information Clonidine is a medicine that is meant to lower the patient's blood pressure. It achieves its purpose as it decreases the levels in which certain chemicals are found in the patient's blood. In this way, the veins and arteries are allowed to widen, enabling the heart to beat regularly. Clonidine indications Clonidine is normally used in the treatment of hypertension (also known as high blood pressure). But Clonidine can also be used for other purposes that have not...
• Difnan - Pharmacological action NSAIDs, a derivative of phenylacetic acid, diclofenac has a pronounced anti-inflammatory, analgesic and mild antipyretic effect. The mechanism of action is associated with inhibition of COX activity - the main enzyme metabolism of arachidonic acid, which is a precursor of prostaglandins, which play a major role in the pathogenesis of inflammation, pain and fever. Analgesic effect is due to two mechanisms: peripheral (indirectly, through suppression of prostaglandin...
• Donepezil - Donepezil (Aricept), is a centrally acting reversible acetyl cholinesterase inhibitor. Its main therapeutic use is in the treatment of Alzheimer’s disease where it is used to increase cortical acetylcholine. Donepezil is postulated to exert its therapeutic effect by enhancing cholinergic function. This is accomplished by increasing the concentration of acetylcholine through reversible inhibition of its hydrolysis by acetylcholinesterase. If this proposed mechanism of action is correct,...
• Enalaprilat - SPL UNCLASSIFIED SECTION                                                                                                                                                                   Rx only WARNING: FETAL TOXICITY ...
• Flumazenil - DESCRIPTION Flumazenil injection is a benzodiazepine receptor antagonist. Chemically, flumazenil is ethyl 8-fluoro-5,6-dihydro-5-methyl-6-oxo-4H-imidazo[1,5-a](1,4) benzodiazepine-3-carboxylate. Flumazenil has an imidazobenzodiazepine structure, a calculated molecular weight of 303.3 and the following structural formula: C 15 H 14 FN 3 O 3 ...
• Fosphenytoin - Fosphenytoin is a water-soluble phenytoin prodrug used only in hospitals for the treatment of epileptic seizures. It works by slowing down impulses in the brain that cause seizures. Its main mechanism is to block frequency-dependent, use-dependent and voltage-dependent neuronal sodium channels, and therefore limit repetitive firing of action potentials. Indication: For the control of generalized convulsive status epilepticus and prevention and treatment of seizures occurring during neurosurgery...
• Gabapentin - Pharmacological action Gabapentin is an antiepileptic drug. Chemical structure is similar to GABA fulfilling the function of the inhibitory neurotransmitter in the CNS. It is believed that the mechanism of action of Gabapentin is different from other anticonvulsants acting through GABA synapses (including valproate, barbiturates, benzodiazepines, inhibitors of GABA-transaminase, inhibitors of GABA capture, GABA agonists and prodrugs of GABA). In in vitro studies showed that Gabapentin is...
• Gemfibrozil - Gemfibrozil information Gemfibrozil is a drug which is usually prescribed along with a diet to people who have very high levels of serum triglycerides (triglycerides are fatty substances from the blood) and who are at a risk of developing pancreatitis (this is the inflammation of the pancreas). This medication may also be used in order to reduce the risk of developing coronary heart disease in people who have not responded to the other therapy options: weight loss, exercises, and diet and...
• Glyburide - DESCRIPTION Glyburide tablets USP contain glyburide, which is an oral blood-glucose-lowering drug of the sulfonylurea class. Glyburide is a white, crystalline compound. The chemical name for glyburide is 1-[[p-[2-(5-chloro-o-anisamido)ethyl]phenyl]-sulfonyl]-3-cyclohexylurea and the molecular weight is 493.99. It has the following structural formula: Molecular formula: C 23 H 28 ClN 3 O 5 S Each tablet,...
• Granisteron
• Irinotecan - Irinotecan is an antineoplastic enzyme inhibitor primarily used in the treatment of colorectal cancer. It is a derivative of camptothecin that inhibits the action of topoisomerase I. Irinotecan prevents religation of the DNA strand by binding to topoisomerase I-DNA complex, and causes double-strand DNA breakage and cell death. Indication: For the treatment of metastatic colorectal cancer (first-line therapy when administered with 5-fluorouracil and leucovorin). Also used in combination with...
• Kamina
• Lamotrigine - WARNING: SERIOUS SKIN RASHES          See full prescribing information for complete boxed warning. Cases of life-threatening serious rashes, including Stevens-Johnson syndrome and toxic...
• Levofloxacin - Indications and Usage Plague (1.14) 04/2012 Dosage and Administration Dosage in Adult Patients with Normal Renal Function (2.1) 04/2012 Dosage in Pediatric Patients (2.2) ...
• Megion
• Metoprolol - Pharmacological action Metoprolol is a cardioselective beta1-blocker without intrinsic sympathomimetic activity. This medication has antihypertensive, antianginal and antiarrhythmic effect. Metoprolol decreases automaticity of sinus node, reducing heart rate, slows AV-conduction, decreases myocardial contractility and excitability, reduces cardiac output, reduces myocardial oxygen demand. This drug inhibits the stimulatory effect of catecholamines on the heart during physical and...
• Miacin
• Milrinone - A positive inotropic cardiotonic agent with vasodilator properties. It inhibits cAMP phosphodiesterase activity in myocardium and vascular smooth muscle. Milrinone is a derivative of amrinone and has 20-30 times the ionotropic potency of amrinone. [PubChem] Indication: Indicated for the treatment of congestive heart failure. Milrinone, a synthetic dimethylxanthine derivative structurally related to theophylline and caffeine, is used in the treatment of peripheral vascular diseases and in the...
• Milrinone in plastic container
• Naproxen - Naproxen information Naproxen is an anti-inflammatory non-steroidal anti-inflammatory (NSAID) medicine. Naproxen Pascual Laboratories's actions help reduce the chemicals found in the patient's organism that are usually responsible for the triggering of inflammation and pain. Naproxen indications Naproxen is a drug normally prescribed in the treatment of pain, stiffness or inflammation that are usually triggered by medical disorders such as Gout, Osteoarthritis, menstruation abdominal...
• Naxan
• Ondansetron - Warnings and Precautions, ( 5.3 ) 09/2014 1 INDICATIONS AND USAGE ZUPLENZ is a 5-HT3 receptor antagonist indicated for: ...
• Oprazole - Pharmacological action Omeprazole is an inhibitor of H+ K+ ATPase. This medication inhibits the activity of H+-K+-ATPase in gastric parietal cells and thus blocks the final stage of hydrochloric acid secretion. This leads to a reduction in basal and stimulated secretion, regardless of the nature of the stimulus. Due to the reduction of acid secretion omeprazole reduces or normalizes the effects of acid in the esophagus in patients with reflux esophagitis. Omeprazole has a bactericidal...
• Progesterone - DESCRIPTION Progesterone injection, a progestin, is a sterile solution of progesterone in a suitable vegetable oil available for intramuscular use. Progesterone occurs as a white or creamy white, crystalline powder. It is odorless and is stable in air. Practically insoluble in water, it is soluble in alcohol, acetone, and dioxane and sparingly soluble in vegetable oils. It has the...
• Promethazine - A phenothiazine derivative with histamine H1-blocking, antimuscarinic, and sedative properties. It is used as an antiallergic, in pruritus, for motion sickness and sedation, and also in animals. [PubChem] Indication: For the treatment of allergic disorders, and nausea/vomiting. Promethazine, a phenothiazine, is an H1-antagonist with anticholinergic, sedative, and antiemetic effects and some local anesthetic properties. Promethazine is used as an antiemetic or to prevent motion sickness.
• Propranolol - Pharmacological action Propranolol is a non-selective beta-blocker. This medication has antihypertensive, antianginal and antiarrhythmic action. The hypotensive effect is associated with a decrease in minute volume of blood, sympathetic stimulation of peripheral vascular disease, decreased activity of the renin-angiotensin system (has a value in patients with initial hypersecretion of renin), sensitivity of baroreceptors of the aortic arch (not going to enhance their activity in response...
• Rosiglitazone - Rosiglitazone is an anti-diabetic drug in the thiazolidinedione class of drugs. It is marketed by the pharmaceutical company GlaxoSmithKline as a stand-alone drug (Avandia) and in combination with metformin (Avandamet) or with glimepiride (Avandaryl).Like other thiazolidinediones, the mechanism of action of rosiglitazone is by activation of the intracellular receptor class of the peroxisome proliferator-activated receptors (PPARs), specifically PPARОі. Rosiglitazone is a selective ligand of...
• Sertraline - Pharmacological action Sertraline (with the generic name of Sertraline) belongs to the groups of drugs known as selective serotonin reuptake inhibitors. These selective serotonin reuptake drugs influence chemical imbalance in the brain responsible for depression, panic anxiety, obsessive compulsive disorder and others. Why is Sertraline prescribed? Sertraline is indicated for the treatment of: depression panic anxiety disorders obsessive compulsive disorder PSTD or post traumatic...
• Suprax - Cefixime is an antibiotic that belongs to the family of medications known as cephalosporins . It is used to treat certain types of bacterial infections. It is most commonly used to treat gonorrhea as well as infections of the ear, sinus, bladder, throat, and lung. Your doctor may have suggested this medication for conditions other than those listed in these drug information articles. As well, some forms of this medication may not be used for all of the conditions discussed here. If you...
• Terbutaline - A selective beta-2 adrenergic agonist used as a bronchodilator and tocolytic. [PubChem] Indication: For the prevention and reversal of bronchospasm in patients 12 years of age and older with reversible, obstructive airway disease, as well as symptomatic management of reversible bronchospasm associated with bronchitis and emphysema. Also used acute IV and sub-Q therapy in selected women to inhibit uterine contractions in preterm labor (tocolysis) and prolong gestation when beneficial....
• Tirotax
• Totam
• Trifed - This combination medication is used to temporarily relieve symptoms caused by the common cold , flu , allergies , or other breathing illnesses (such as sinusitis , bronchitis ). Antihistamines help relieve watery eyes , itchy eyes/nose/throat, runny nose, and sneezing. Decongestants help to relieve stuffy nose and ear congestion symptoms. If you are self-treating with this medication, carefully read the package instructions to be sure it is right for you before you start using...
• Trifed Expectorant
• Valproate
• Vinone
• Zolpidem - Zolpidem is a prescription short-acting nonbenzodiazepine hypnotic that potentiates gamma-aminobutyric acid (GABA), an inhibitory neurotransmitter, by binding to benzodiazepine receptors which are located on the gamma-aminobutyric acid receptors. Zolpidem is used for the short-term treatment of insomnia. It works quickly (usually within 15 minutes) and has a short half-life (2-3 hours). It is classified as an imidazopyridine. As an anticonvulsant and muscle relaxant, the beneficial effects...

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The information was verified by Dr. Rachana Salvi, MD Pharmacology