Vernarin

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Vernarin uses


Pharmacological action

Vernarin is a calcium channel blocker class IV with a predominant effect on the brain vessels, a derivative of piperazine. This medication improves cerebral, coronary and peripheral circulation. Vernarin violates the entrance of calcium ions into vascular smooth muscle cells. This drug lowers the tone of arteriolar smooth muscle, decreases the vasoconstrictor response to biogenic substances. Vernarin reduces the excitability of the vestibular apparatus. In patients with impaired peripheral circulation Vernarin improves blood flow and potentiates postischemic hyperemia. This medicine increases the resistance of tissue to hypoxia.

Pharmacokinetics

After oral administration Vernarin is absorbed from the gastrointestinal tract, Cmax in plasma is reached after 1-4 h. The plasma protein binding is 91%. This medication is metabolized. T1/2 is 3-6 hours. Vernarin is eliminated through the intestine largely unchanged, with the urine - mainly in the form of metabolites.

Why is Vernarin prescribed?

Ischemic attacks. Labyrinth disorders (including for maintenance therapy for dizziness, tinnitus, nystagmus, nausea and vomiting of labyrinth origin). Motion sickness (as a prophylactic agent). Prophylaxis of migraine. Meniere's disease. Prevention and treatment of disorders of peripheral circulation - atherosclerosis, thromboangiitis obliterans, Raynaud's disease, diabetic angiopathy, acrocyanosis.

Dosage and administration

The dosage regimen is individual. Vernarin is taken orally in 25-50-75 mg 3 times / day after a meal. If necessary, the treatment can begin with half the dose and gradually increasing. To achieve the optimal therapeutic effect is used continuously for several months.

Vernarin side effects, adverse reactions

Digestive system: dyspepsia, dry mouth, rarely - cholestatic jaundice.

CNS: headache, drowsiness; in elderly patients in long-term use may be extrapyramidal symptoms, depression.

Allergic reactions: rarely - skin rash.

Other: weight gain, increased sweating, in rare cases - lupus-like syndrome, lichen planus.

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Vernarin contraindications

Hypersensitivity to Vernarin.

Using during pregnancy and breastfeeding

During pregnancy and lactation Vernarin usage is possible only in exceptional cases, when the expected benefit to the mother far outweighs the potential risk to the fetus or infant.

Special instructions

Use Vernarin with caution in patients with hypertension.

With prolonged use is recommended to perform control examination of liver, kidney, peripheral blood picture.

At the beginning of treatment you should refrain from potentially hazardous activities that require attention and speed of psychomotor reactions.

Vernarin drug interactions

When this drug applied simultaneously with:

- tricyclic antidepressants, hypnotics, drugs that have a sedative effect, alcohol, ethanol-containing medication increases the effects on the CNS.

- antihypertensive drugs increased hypotensive effect.

- nootropics, vasodilators - increases the action of nootropic drugs and vasodilators.

- phenylpropanolamine reduces sedation effect of Vernarin Quality Pharmaceutical Laboratory.

Vernarin in case of emergency / overdose

Treatment: gastric lavage, taking activated charcoal, symptomatic therapy. There is no a specific antidote.

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Frequently asked Questions

Can i drive or operate heavy machine after consuming Vernarin?

Depending on the reaction of the Vernarin after taken, if you are feeling dizziness, drowsiness or any weakness as a reaction on your body, Then consider Vernarin not safe to drive or operate heavy machine after consumption. Meaning that, do not drive or operate heavy duty machines after taking the capsule if the capsule has a strange reaction on your body like dizziness, drowsiness. As prescribed by a pharmacist, it is dangerous to take alcohol while taking medicines as it exposed patients to drowsiness and health risk. Please take note of such effect most especially when taking Primosa capsule. It's advisable to consult your doctor on time for a proper recommendation and medical consultations.

Is Vernarin addictive or habit forming?

Medicines are not designed with the mind of creating an addiction or abuse on the health of the users. Addictive Medicine is categorically called Controlled substances by the government. For instance, Schedule H or X in India and schedule II-V in the US are controlled substances.

Please consult the medicine instruction manual on how to use and ensure it is not a controlled substance.In conclusion, self medication is a killer to your health. Consult your doctor for a proper prescription, recommendation, and guidiance.

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Review

sdrugs.com conducted a study on Vernarin, and the result of the survey is set out below. It is noteworthy that the product of the survey is based on the perception and impressions of the visitors of the website as well as the views of Vernarin consumers. We, as a result of this, advice that you do not base your therapeutic or medical decisions on this result, but rather consult your certified medical experts for their recommendations.

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The information was verified by Dr. Rachana Salvi, MD Pharmacology

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