DRUGS & SUPPLEMENTS

Topiramate

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Topiramate uses


Topiramate (brand name Topamax) is an anticonvulsant drug produced by Ortho-McNeil Neurologics, a division of Johnson & Johnson. It is used to treat epilepsy in both children and adults. In children it is also indicated for treatment of Lennox-Gastaut syndrome (a disorder that causes seizures and developmental delays). It is also Food and Drug Administration (FDA) approved for, and now most frequently prescribed for, the prevention of migraines. [Wikipedia]

Indication: Used for the treatment and control of partial seizures and severe tonic-clonic (grand mal) seizures and also for the prevention of migraine headaches. In children it is also used for treatment of Lennox-Gastaut syndrome.

Topiramate is an anticonvulsant indicated in the treatment of epilepsy and migraine. Topiramate enhances GABA-activated chloride channels. In addition, Topiramate inhibits excitatory neurotransmission, through actions on kainate and AMPA receptors. There is evidence that Topiramate has a specific effect on GluR5 kainate receptors. It is also an inhibitor of carbonic anhydrase, particular subtypes II and IV, but this action is weak and unlikely to be related to its anticonvulsant actions, but may account for the bad taste and the development of renal stones seen during treatment. Its possible effect as a mood stabilizer seems to occur before anticonvulsant qualities at lower dosages. Topiramate inhibits maximal electroshock and pentylenetetrazol-induced seizures as well as partial and secundarily generalized tonic-clonic seizures in the kindling model, findings predective of a broad spectrum of antiseizure activities clinically.

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Topiramate pharmaceutical active ingredients containing related brand and generic drugs:

infoActive ingredient is the part of the drug or medicine which is biologically active. This portion of the drug is responsible for the main action of the drug which is intended to cure or reduce the symptom or disease. The other portions of the drug which are inactive are called excipients; there role is to act as vehicle or binder. In contrast to active ingredient, the inactive ingredient's role is not significant in the cure or treatment of the disease. There can be one or more active ingredients in a drug.


Topiramate available forms, composition, doses:

infoForm of the medicine is the form in which the medicine is marketed in the market, for example, a medicine X can be in the form of capsule or the form of chewable tablet or the form of tablet. Sometimes same medicine can be available as injection form. Each medicine cannot be in all forms but can be marketed in 1, 2, or 3 forms which the pharmaceutical company decided based on various background research results.
Composition is the list of ingredients which combinedly form a medicine. Both active ingredients and inactive ingredients form the composition. The active ingredient gives the desired therapeutic effect whereas the inactive ingredient helps in making the medicine stable.
Doses are various strengths of the medicine like 10mg, 20mg, 30mg and so on. Each medicine comes in various doses which is decided by the manufacturer, that is, pharmaceutical company. The dose is decided on the severity of the symptom or disease.

Price
Capsules; Oral; Topiramate 15 mg
Capsules; Oral; Topiramate 25 mg
Co Topiramate 100 mg Tablet1.31 USD
Co Topiramate 200 mg Tablet2.08 USD
Co Topiramate 25 mg Tablet0.69 USD
Mylan-Topiramate 100 mg Tablet1.31 USD
Mylan-Topiramate 200 mg Tablet2.08 USD
Mylan-Topiramate 25 mg Tablet0.69 USD
Novo-Topiramate 100 mg Tablet1.31 USD
Novo-Topiramate 200 mg Tablet2.08 USD
Novo-Topiramate 25 mg Tablet0.69 USD
Phl-Topiramate 100 mg Tablet1.31 USD
Phl-Topiramate 200 mg Tablet2.08 USD
Phl-Topiramate 25 mg Tablet0.69 USD
Pms-Topiramate 100 mg Tablet1.31 USD
Pms-Topiramate 200 mg Tablet2.08 USD
Pms-Topiramate 25 mg Tablet0.69 USD
Pms-Topiramate 50 mg Tablet1.05 USD
Ratio-Topiramate 100 mg Tablet1.31 USD
Ratio-Topiramate 200 mg Tablet2.08 USD
Ratio-Topiramate 25 mg Tablet0.69 USD
Sandoz Topiramate 100 mg Tablet1.31 USD
Sandoz Topiramate 200 mg Tablet2.08 USD
Sandoz Topiramate 25 mg Tablet0.69 USD
Tablets; Oral; Topiramate 100 mg
Tablets; Oral; Topiramate 200 mg
Tablets; Oral; Topiramate 25 mg
Tablets; Oral; Topiramate 50 mg
Topamax 100 mg tablet6.31 USD
Topamax 200 mg tablet7.68 USD
Topamax 25 mg tablet2.46 USD
Topamax 50 mg tablet5.96 USD
Topamax Sprinkle 15 mg Capsule1.29 USD
Topamax Sprinkle 25 mg Capsule1.35 USD
Topiramate 100 mg tablet7.11 USD
Topiramate 15 mg Sprinkle Capsule2.52 USD
Topiramate 200 mg tablet8.32 USD
Topiramate 25 mg Sprinkle Capsule3.04 USD
Topiramate 25 mg tablet2.61 USD
Topiramate 50 mg tablet5.21 USD
Topiramate 99.7% powder2.59 USD

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Topiramate destination | category:

infoDestination is defined as the organism to which the drug or medicine is targeted. For most of the drugs what we discuss, human is the drug destination.
Drug category can be defined as major classification of the drug. For example, an antihistaminic or an antipyretic or anti anginal or pain killer, anti-inflammatory or so.


Topiramate Anatomical Therapeutic Chemical codes:

infoA medicine is classified depending on the organ or system it acts [Anatomical], based on what result it gives on what disease, symptom [Therapeutical], based on chemical composition [Chemical]. It is called as ATC code. The code is based on Active ingredients of the medicine. A medicine can have different codes as sometimes it acts on different organs for different indications. Same way, different brands with same active ingredients and same indications can have same ATC code.


Topiramate pharmaceutical companies:

infoPharmaceutical companies are drug manufacturing companies that help in complete development of the drug from the background research to formation, clinical trials, release of the drug into the market and marketing of the drug.
Researchers are the persons who are responsible for the scientific research and is responsible for all the background clinical trials that resulted in the development of the drug.


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References

  1. Dailymed."TOPIRAMATE TABLET, FILM COATED [BRYANT RANCH PREPACK]". https://dailymed.nlm.nih.gov/dailym... (accessed August 28, 2018).
  2. Dailymed."TOPIRAMATE: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailym... (accessed August 28, 2018).
  3. "topiramate". https://pubchem.ncbi.nlm.nih.gov/co... (accessed August 28, 2018).

Frequently asked Questions

Can i drive or operate heavy machine after consuming Topiramate?

Depending on the reaction of the Topiramate after taken, if you are feeling dizziness, drowsiness or any weakness as a reaction on your body, Then consider Topiramate not safe to drive or operate heavy machine after consumption. Meaning that, do not drive or operate heavy duty machines after taking the capsule if the capsule has a strange reaction on your body like dizziness, drowsiness. As prescribed by a pharmacist, it is dangerous to take alcohol while taking medicines as it exposed patients to drowsiness and health risk. Please take note of such effect most especially when taking Primosa capsule. It's advisable to consult your doctor on time for a proper recommendation and medical consultations.

Is Topiramate addictive or habit forming?

Medicines are not designed with the mind of creating an addiction or abuse on the health of the users. Addictive Medicine is categorically called Controlled substances by the government. For instance, Schedule H or X in India and schedule II-V in the US are controlled substances.

Please consult the medicine instruction manual on how to use and ensure it is not a controlled substance.In conclusion, self medication is a killer to your health. Consult your doctor for a proper prescription, recommendation, and guidiance.

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Review

sDrugs.com conducted a study on Topiramate, and the result of the survey is set out below. It is noteworthy that the product of the survey is based on the perception and impressions of the visitors of the website as well as the views of Topiramate consumers. We, as a result of this, advice that you do not base your therapeutic or medical decisions on this result, but rather consult your certified medical experts for their recommendations.

Visitor reports

One visitor reported time for results

What is the time duration Topiramate drug must be taken for it to be effective or for it to reduce the symptoms?
Most chronic conditions need at least some time so the dose and the drug action gets adjusted to the body to get the desired effect. The stastistics say sDrugs.com website users needed 1 day to notice the result from using Topiramate drug. The time needed to show improvement in health condition after using the medicine Topiramate need not be same for all the users. It varies based on other factors.
Visitors%
1 day1
100.0%

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The information was verified by Dr. Arunabha Ray, MD Pharmacology

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