DRUGS & SUPPLEMENTS

Terfamex

Rating: 2.5 - 2 review(s)
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Terfamex uses


What is Terfamex?

Terfamex is an appetite suppressant of a pharmacological group of amphetamines and phenethylamines. This medication was approved to help reduce weight in obese patients for short-term use and combination with exercise, diet and behavior changes. It usually prescribed to individuals who have health risks due to their weight. This active ingredient Terfamex is manufactured and distributed in various countries under different trade brand and generic names, for example: Adipex-P (Teva), Ionamin (Celltech), Acxion (Investigacion Farmaceutica), Fastin (GlaxoSmithKline), Duromine (iNova, Douglas Pharmaceuticals), Panbesy (Eurodrug Laboratories), Terfamex (KVK-TECH), Terfamex (Eon Labs), etc. In several countries (such as the USA, Canada, Australia) this drug is a controlled substance because it can cause addiction.

Pharmacological action

Terfamex acts on the brain neurotransmitters. Terfamex is a central stimulant and an isomer of methamphetamine. It stimulates neurons to release a particular group of neurotransmitters known as catecholamines among which are dopamine, epinephrine (also called adrenaline) and norepinephrine. The appetite suppression activity of these compounds is due to its action on the central nervous system. This mechanism of action is similar to other stimulant appetite suppressants such as diethylpropion and phendimetrazine. The neurotransmitters signal the alert response which also stops the hunger.

Why is Terfamex prescribed?

Terfamex is used to reduce body weight in obese or overweight patients. Often it prescribed in a regimen of weight reduction based on exercise, behavioral modification, and caloric restriction in the management of exogenous obesity for obese or overweight patients with the presence of other risk factors. Terfamex works by directly affecting the area of the brain that controls your appetite making you feel less hungry.

Dosage and administration

It is recommended to use Terfamex only in the short term (usually about 12 weeks) and then other non-pharmacological strategies for weight loss and healthy dieting and exercise. However, recommendations limiting its use for short-term treatment are controversial. One reason for the restriction to 12 weeks is drug tolerance, as Terfamex loses its appetite-suppressing effects after the body adjusts. On the contrary, it has been shown that this drug did not lose its effect in a trial of 36 weeks. Due to the risk of insomnia, it is recommended taking Terfamex before breakfast or 1-2 hours later.

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Terfamex side effects, adverse reactions

Generally, Terfamex is relatively well tolerated but can cause some side effects because it releases catecholamines. Among the most common effects include: tachycardia, elevated blood pressure, palpitations, nervousness, irritability and insomnia. Additionally, if Terfamex is taken for long term, it may develop euphoria and addiction. Other less common side effects include blurred vision, changes in sex drive, clumsiness, confusion, diarrhea, dizziness, dry mouth, headache, irregular heartbeat, nausea or vomiting, psychosis, skin rash or itching, stomach pain, fatigue and bad taste.

Contraindications

The following people should not use Terfamex:

  • Allergy to any ingredient of Terfamex containing pharmaceutical form (usually capsules or tablets) or other sympathomimetic (eg, pseudoephedrine).
  • Taking dexfenfluramine, fenfluramine, furazolidone, guanadrel, guanethidine, or have taken of mono-amine oxidase inhibitors (MAOIs) (eg., phenelzine) in the last 14 days.
  • With high blood pressure or moderate hyperthyroidism, glaucoma, heart or circulatory disease, or severe narrowing of blood vessels.
  • Who are in a state of agitation or have a history of alcohol or drug abuse.

    Terfamex using during pregnancy and breastfeeding

    There is no data whether Terfamex can cause fetal harm when administered to a pregnant woman or can affect reproductive capacity. Thats why rgis drugs should be given to a pregnant woman only if clearly needed.

    Because of the potential for serious adverse reactions in nursing infants, a decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother.

    Safety and effectiveness of Terfamex in pediatric patients have not been established.

    Special instructions

    You healthcare professional should be informed of the following conditions:

  • If you are pregnant or plan to become pregnant or if you are breastfeeding (lactation).
  • If you are taking prescription or nonprescription medications, herbal preparations or dietary supplements.
  • If you have allergies to medicines, foods or other substances.
  • If you have a brain disorder or spinal cord, narrowing of the arteries, high blood pressure (hypertension), diabetes or high cholesterol or lipids.

    Terfamex drug interactions

    The following drugs can interact with Terfamex Quality Pharmaceutical Laboratory:

  • Dexfenfluramine, fenfluramine, furazolidone, or inhibitors of MAO (eg., phenelzine) because the risk of serious side effects such as headaches, high blood pressure, low pulse, elevated temperature or fatal lung problems.
  • Inhibitors of serotonin reuptake (such as fluoxetine).
  • Guanadrel or guanethidine because their effectiveness may be decreased by Terfamex.

    Terfamex in case of emergency / overdose

    In case of overdose of Terfamex Quality Pharmaceutical Laboratory, call your local poison control center or local emergency services.

    Manifestations of acute overdosage with Terfamex include restlessness, hyperreflexia, tremor, confusion, assaultiveness, rapid respiration, hallucinations, panic states. Fatigue and depression usually follow the central stimulation. Cardiovascular effects include hypertension or hypotension, arrhythmia, and circulatory collapse. Gastrointestinal symptoms include vomiting, nausea, diarrhea and abdominal cramps. Fatal poisoning usually terminates in convulsions and coma.

    Management of acute Terfamex intoxication is largely symptomatic and includes lavage and sedation with a barbiturate. Hemodialysis or peritoneal dialysis is ineffective and not recommended in this regard.

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    Terfamex pharmaceutical active ingredients containing related brand and generic drugs:

    infoActive ingredient is the part of the drug or medicine which is biologically active. This portion of the drug is responsible for the main action of the drug which is intended to cure or reduce the symptom or disease. The other portions of the drug which are inactive are called excipients; there role is to act as vehicle or binder. In contrast to active ingredient, the inactive ingredient's role is not significant in the cure or treatment of the disease. There can be one or more active ingredients in a drug.


    Terfamex available forms, composition, doses:

    infoForm of the medicine is the form in which the medicine is marketed in the market, for example, a medicine X can be in the form of capsule or the form of chewable tablet or the form of tablet. Sometimes same medicine can be available as injection form. Each medicine cannot be in all forms but can be marketed in 1, 2, or 3 forms which the pharmaceutical company decided based on various background research results.
    Composition is the list of ingredients which combinedly form a medicine. Both active ingredients and inactive ingredients form the composition. The active ingredient gives the desired therapeutic effect whereas the inactive ingredient helps in making the medicine stable.
    Doses are various strengths of the medicine like 10mg, 20mg, 30mg and so on. Each medicine comes in various doses which is decided by the manufacturer, that is, pharmaceutical company. The dose is decided on the severity of the symptom or disease.


    Terfamex destination | category:

    infoDestination is defined as the organism to which the drug or medicine is targeted. For most of the drugs what we discuss, human is the drug destination.
    Drug category can be defined as major classification of the drug. For example, an antihistaminic or an antipyretic or anti anginal or pain killer, anti-inflammatory or so.


    Terfamex Anatomical Therapeutic Chemical codes:

    infoA medicine is classified depending on the organ or system it acts [Anatomical], based on what result it gives on what disease, symptom [Therapeutical], based on chemical composition [Chemical]. It is called as ATC code. The code is based on Active ingredients of the medicine. A medicine can have different codes as sometimes it acts on different organs for different indications. Same way, different brands with same active ingredients and same indications can have same ATC code.


    Terfamex pharmaceutical companies:

    infoPharmaceutical companies are drug manufacturing companies that help in complete development of the drug from the background research to formation, clinical trials, release of the drug into the market and marketing of the drug.
    Researchers are the persons who are responsible for the scientific research and is responsible for all the background clinical trials that resulted in the development of the drug.


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    References

    1. Dailymed."PHENTERMINE HYDROCHLORIDE TABLET [BRYANT RANCH PREPACK]". https://dailymed.nlm.nih.gov/dailym... (accessed August 28, 2018).
    2. "phentermine". https://pubchem.ncbi.nlm.nih.gov/co... (accessed August 28, 2018).
    3. "phentermine". http://www.drugbank.ca/drugs/DB0019... (accessed August 28, 2018).

    Frequently asked Questions

    Can i drive or operate heavy machine after consuming Terfamex?

    Depending on the reaction of the Terfamex after taken, if you are feeling dizziness, drowsiness or any weakness as a reaction on your body, Then consider Terfamex not safe to drive or operate heavy machine after consumption. Meaning that, do not drive or operate heavy duty machines after taking the capsule if the capsule has a strange reaction on your body like dizziness, drowsiness. As prescribed by a pharmacist, it is dangerous to take alcohol while taking medicines as it exposed patients to drowsiness and health risk. Please take note of such effect most especially when taking Primosa capsule. It's advisable to consult your doctor on time for a proper recommendation and medical consultations.

    Is Terfamex addictive or habit forming?

    Medicines are not designed with the mind of creating an addiction or abuse on the health of the users. Addictive Medicine is categorically called Controlled substances by the government. For instance, Schedule H or X in India and schedule II-V in the US are controlled substances.

    Please consult the medicine instruction manual on how to use and ensure it is not a controlled substance.In conclusion, self medication is a killer to your health. Consult your doctor for a proper prescription, recommendation, and guidiance.

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    Review

    sDrugs.com conducted a study on Terfamex, and the result of the survey is set out below. It is noteworthy that the product of the survey is based on the perception and impressions of the visitors of the website as well as the views of Terfamex consumers. We, as a result of this, advice that you do not base your therapeutic or medical decisions on this result, but rather consult your certified medical experts for their recommendations.

    Visitor reports

    Two visitors reported side effects

    Did you get side effects while taking the Terfamex drug, or were there no side effects?
    According to the survey conducted by website sDrugs.com users, the below-mentioned percentages indicate the number of people experiencing the side effects and the number of people not experiencing the side effects when taking Terfamex medicine. Every drug produces minimal side effects, and they are negligible most times, when compared to the desired effect [use] of the medicine. Side effects depend on the dose you are taking, any drug interactions that happen when you are on other medications, if the patient is sensitive, and other associated conditions. If you cannot tolerate the side effects, consult your doctor immediately, so he can either adjust the dose or change the medication.
    Visitors%
    No side effects1
    50.0%
    It has side effects1
    50.0%

    Four visitors reported frequency of use

    How often in a day do you take the medicine?
    Are you taking the Terfamex drug as prescribed by the doctor?

    Few medications can be taken Once in a day more than prescribed when the doctor's advice mentions the medicine can be taken according to frequency or severity of symptoms. Most times, be very careful and clear about the number of times you are taking the medication. The report of sDrugs.com website users about the frequency of taking the drug Terfamex is mentioned below.
    Visitors%
    Once in a day2
    50.0%
    Twice in a day1
    25.0%
    3 times in a day1
    25.0%

    Eight visitors reported doses

    What is the dose of Terfamex drug you are taking?
    According to the survey conducted among sDrugs.com website users, the maximum number of people are using the following dose 11-50mg. Few medications come in only one or two doses. Few are specific for adult dose and child dose. The dose of the medicine given to the patient depends on the severity of the symptom/disease. There can be dose adjustments made by the doctor, based on the progression of the disease. Follow-up is important.
    Visitors%
    11-50mg7
    87.5%
    51-100mg1
    12.5%

    Three visitors reported time for results

    What is the time duration Terfamex drug must be taken for it to be effective or for it to reduce the symptoms?
    Most chronic conditions need at least some time so the dose and the drug action gets adjusted to the body to get the desired effect. The stastistics say sDrugs.com website users needed > 3 month to notice the result from using Terfamex drug. The time needed to show improvement in health condition after using the medicine Terfamex need not be same for all the users. It varies based on other factors.
    Visitors%
    > 3 month1
    33.3%
    3 days1
    33.3%
    1 week1
    33.3%

    Seven visitors reported age

    Visitors%
    30-453
    42.9%
    46-602
    28.6%
    16-292
    28.6%

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    The information was verified by Dr. Arunabha Ray, MD Pharmacology

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