Tareg

Rating: 3.75 - 4 review(s)
What is the dose of the medication you are taking?
advertisement

Tareg uses


Pharmacological action

Tareg is an antihypertensive drug. This medication is a specific antagonist of angiotensin II. It has a selective antagonistic effect on AT1-receptors, which are responsible for implementing the effects of angiotensin II.

Due to the blockade of AT1-receptors the plasma concentrations of angiotensin II increased, which may stimulate the unblocked AT2-receptors. This medicine has no agonistic activity against AT1-receptor. The affinity of Tareg for AT1-receptors in about 20 000 times higher than that of AT2-receptors.

Tareg does not inhibit ACE. This drug has no interaction and does not block other hormone receptors or ion channels important for regulation of the cardiovascular system.

This medication has no effect on total cholesterol, triglycerides, glucose and uric acid in blood plasma.

A start of antihypertensive action of Tareg after its oral administration in a single dose occurs within 2 h after administration, the maximum effect is achieved within 4-6 h.

Pharmacokinetics

After oral administration Tareg is rapidly absorbed from the gastrointestinal tract, the extent of absorption is characterized by individual differences. The absolute bioavailability is average 23%.

In course of treatment with this medication there were not noted changes of pharmacokinetic parameters.

When administered with food Tareg AUC decreased by 48%, with approximately 8 hours after administration of Tareg in plasma concentrations of the same in patients taking it with food and fasting. AUC decrease is not accompanied by clinically significant reduction in therapeutic effect.

When you receive Tareg 1 time / day the accumulation is expressed only slightly. The concentration of Tareg in the blood plasma of women and men were equal. The binding with plasma proteins, primarily to albumin is 94-97%.

The plasma clearance of Tareg is about 2 L / h. This medication is excreted in the feces 70% and in urine 30%, largely unchanged.

When biliary cirrhosis or biliary obstruction AUC of Tareg is increased approximately 2-fold.

advertisement

Why is Tareg prescribed?

A treatment of hypertension. A treatment of chronic heart failure in patients receiving conventional therapy with diuretics, digitalis preparations, as well as ACE inhibitors or beta-blockers.

Dosage and administration

Tareg is taken orally in dose 80 mg daily 1 time / day or 40 mg 2 times / day. In the absence of adequate effect the daily dose may be gradually increased. The maximum daily dose is 320 mg in 2 divided doses.

Tareg side effects, adverse reactions

Cardiovascular system: hypotension, postural dizziness, postural hypotension.

CNS: dizziness, headache.

Digestive system: diarrhea, nausea, increased bilirubin levels.

Urinary system: rarely - renal failure, increased creatinine and BUN.

Metabolic: hyperkalemia.

Hematopoietic system: neutropenia, a decrease in hemoglobin and hematocrit.

Allergic reactions: rarely - angioedema, rash, pruritus, serum sickness, vasculitis.

Other: fatigue, weakness, cough, sore throat, increased risk of viral infections.

Tareg contraindications

Pregnancy, hypersensitivity to Tareg.

Using during pregnancy and breastfeeding

Tareg is contraindicated during pregnancy. It is not known whether Tareg is allocated to breast milk in humans. Use during lactation is not recommended.

Experimental studies have shown that this medication is excreted in breast milk of rats.

Category of the fetus by FDA - D.

Special instructions

When hyponatremia and / or reduction of the BCC, as well as during treatment with high doses of diuretics, Tareg, in rare cases can cause pronounced hypotension.

Before starting treatment it should be the correction of violations of water-salt metabolism.

In patients with renovascular hypertension, which developed secondary to renal artery stenosis, in the period of treatment should regularly monitor the level of urea and creatinine in serum. There is no data on the safety of patients with CC than 10 ml / min.

With great caution use in patients with impaired patency of the biliary tract.

Due to inhibition of the RAAS in patients predisposed to changes in renal function.

With use of ACE inhibitors and angiotensin receptor antagonists in patients with chronic heart failure severity of the observed oliguria and / or increase azotemia, rarely developed acute renal failure with risk of death.

Safety and efficacy of Tareg in children has not been established.

If use Tareg it is recommended a caution when driving and management mechanisms.

Tareg drug interactions

When this drug applied simultaneously with:

- diuretics in high doses it may developed hypotension.

- potassium-sparing diuretics, heparin, dietary supplements or salt substitutes containing potassium may develop hyperkalemia.

- indomethacin may decrease the antihypertensive action of Tareg.

- lithium carbonate, described the case of lithium toxicity.

Tareg in case of emergency / overdose

Symptoms: hypotension, tachycardia or bradycardia.

Treatment: symptomatic therapy, dialysis is not effective.

advertisement

Tareg pharmaceutical active ingredients containing related brand and generic drugs:

Active ingredient is the part of the drug or medicine which is biologically active. This portion of the drug is responsible for the main action of the drug which is intended to cure or reduce the symptom or disease. The other portions of the drug which are inactive are called excipients; there role is to act as vehicle or binder. In contrast to active ingredient, the inactive ingredient's role is not significant in the cure or treatment of the disease. There can be one or more active ingredients in a drug.


Tareg available forms, composition, doses:

Form of the medicine is the form in which the medicine is marketed in the market, for example, a medicine X can be in the form of capsule or the form of chewable tablet or the form of tablet. Sometimes same medicine can be available as injection form. Each medicine cannot be in all forms but can be marketed in 1, 2, or 3 forms which the pharmaceutical company decided based on various background research results.
Composition is the list of ingredients which combinedly form a medicine. Both active ingredients and inactive ingredients form the composition. The active ingredient gives the desired therapeutic effect whereas the inactive ingredient helps in making the medicine stable.
Doses are various strengths of the medicine like 10mg, 20mg, 30mg and so on. Each medicine comes in various doses which is decided by the manufacturer, that is, pharmaceutical company. The dose is decided on the severity of the symptom or disease.


Tareg destination | category:

Destination is defined as the organism to which the drug or medicine is targeted. For most of the drugs what we discuss, human is the drug destination.
Drug category can be defined as major classification of the drug. For example, an antihistaminic or an antipyretic or anti anginal or pain killer, anti-inflammatory or so.


Tareg Anatomical Therapeutic Chemical codes:

A medicine is classified depending on the organ or system it acts [Anatomical], based on what result it gives on what disease, symptom [Therapeutical], based on chemical composition [Chemical]. It is called as ATC code. The code is based on Active ingredients of the medicine. A medicine can have different codes as sometimes it acts on different organs for different indications. Same way, different brands with same active ingredients and same indications can have same ATC code.


Tareg pharmaceutical companies:

Pharmaceutical companies are drug manufacturing companies that help in complete development of the drug from the background research to formation, clinical trials, release of the drug into the market and marketing of the drug.
Researchers are the persons who are responsible for the scientific research and is responsible for all the background clinical trials that resulted in the development of the drug.


advertisement

References

  1. Dailymed."DIOVAN (VALSARTAN) TABLET [LAKE ERIE MEDICAL & SURGICAL SUPPLY DBA QUALITY CARE PRODUCTS LLC]". https://dailymed.nlm.nih.gov/dailym... (accessed August 28, 2018).
  2. Dailymed."AMLODIPINE BESYLATE; VALSARTAN: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailym... (accessed August 28, 2018).
  3. "valsartan". https://pubchem.ncbi.nlm.nih.gov/co... (accessed August 28, 2018).

Frequently asked Questions

Can i drive or operate heavy machine after consuming Tareg?

Depending on the reaction of the Tareg after taken, if you are feeling dizziness, drowsiness or any weakness as a reaction on your body, Then consider Tareg not safe to drive or operate heavy machine after consumption. Meaning that, do not drive or operate heavy duty machines after taking the capsule if the capsule has a strange reaction on your body like dizziness, drowsiness. As prescribed by a pharmacist, it is dangerous to take alcohol while taking medicines as it exposed patients to drowsiness and health risk. Please take note of such effect most especially when taking Primosa capsule. It's advisable to consult your doctor on time for a proper recommendation and medical consultations.

Is Tareg addictive or habit forming?

Medicines are not designed with the mind of creating an addiction or abuse on the health of the users. Addictive Medicine is categorically called Controlled substances by the government. For instance, Schedule H or X in India and schedule II-V in the US are controlled substances.

Please consult the medicine instruction manual on how to use and ensure it is not a controlled substance.In conclusion, self medication is a killer to your health. Consult your doctor for a proper prescription, recommendation, and guidiance.

advertisement

Review

sdrugs.com conducted a study on Tareg, and the result of the survey is set out below. It is noteworthy that the product of the survey is based on the perception and impressions of the visitors of the website as well as the views of Tareg consumers. We, as a result of this, advice that you do not base your therapeutic or medical decisions on this result, but rather consult your certified medical experts for their recommendations.

Visitor reports

Two visitors reported useful

How is the drug Tareg useful in reducing or relieving the symptoms? How useful is it?
According to the survey conducted by the website sdrugs.com, there are variable results and below are the percentages of the users that say the medicine is useful to them and that say it is not helping them much. It is not ideal to continue taking the medication if you feel it is not helping you much. Contact your healthcare provider to check if there is a need to change the medicine or if there is a need to re-evaluate your condition. The usefulness of the medicine may vary from patient to patient, depending on the other diseases he is suffering from and slightly depends on the brand name.
Visitors%
Useful2
100.0%

One visitor reported side effects

Did you get side effects while taking the Tareg drug, or were there no side effects?
According to the survey conducted by website sdrugs.com users, the below-mentioned percentages indicate the number of people experiencing the side effects and the number of people not experiencing the side effects when taking Tareg medicine. Every drug produces minimal side effects, and they are negligible most times, when compared to the desired effect [use] of the medicine. Side effects depend on the dose you are taking, any drug interactions that happen when you are on other medications, if the patient is sensitive, and other associated conditions. If you cannot tolerate the side effects, consult your doctor immediately, so he can either adjust the dose or change the medication.
Visitors%
No side effects1
100.0%

One visitor reported price estimates

What is your opinion about drug cost? Did you feel the cost is apt, or did you feel it is expensive?
The report given by the sdrugs.com website users shows the following figures about several people who felt the medicine Tareg is expensive, and the medicine is not expensive. The results are mixed. The perception of the cost of the medicine to be expensive or not depends on the brand name of the medicine, country, and place where it is sold, and the affordability of the patient. You can choose a generic drug in the place of the branded drug to save the cost. The efficiency of the medicine will not vary if it is generic or a branded one.
Visitors%
Expensive1
100.0%

Two visitors reported frequency of use

How often in a day do you take the medicine?
Are you taking the Tareg drug as prescribed by the doctor?

Few medications can be taken Once in a day more than prescribed when the doctor's advice mentions the medicine can be taken according to frequency or severity of symptoms. Most times, be very careful and clear about the number of times you are taking the medication. The report of sdrugs.com website users about the frequency of taking the drug Tareg is mentioned below.
Visitors%
Once in a day2
100.0%

Six visitors reported doses

What is the dose of Tareg drug you are taking?
According to the survey conducted among sdrugs.com website users, the maximum number of people are using the following dose 51-100mg. Few medications come in only one or two doses. Few are specific for adult dose and child dose. The dose of the medicine given to the patient depends on the severity of the symptom/disease. There can be dose adjustments made by the doctor, based on the progression of the disease. Follow-up is important.
Visitors%
51-100mg3
50.0%
101-200mg2
33.3%
11-50mg1
16.7%

Three visitors reported time for results

What is the time duration Tareg drug must be taken for it to be effective or for it to reduce the symptoms?
Most chronic conditions need at least some time so the dose and the drug action gets adjusted to the body to get the desired effect. The stastistics say sdrugs.com website users needed 5 days to notice the result from using Tareg drug. The time needed to show improvement in health condition after using the medicine Tareg need not be same for all the users. It varies based on other factors.
Visitors%
5 days1
33.3%
1 day1
33.3%
2 weeks1
33.3%

Visitor reported administration

No survey data has been collected yet

Five visitors reported age

Visitors%
> 604
80.0%
46-601
20.0%

Visitor reviews


There are no reviews yet. Be the first to write one!


Your name: 
Email: 
Spam protection:  < Type 3 here

The information was verified by Dr. Rachana Salvi, MD Pharmacology

© 2002 - 2022 "sdrugs.com". All Rights Reserved