Speridon Plus

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Speridon Plus uses

Speridon Plus consists of Risperidone, Trihexyphenidyl.

Risperidone:


Speridon Plus information

This medication works well for patients suffering from the agonies of bipolar diseases. Mostly, Speridon Plus (Risperidone) helps individuals with schizophrenia and mania. By affecting the functions of different chemicals in the brain, this drug may provide relief to sufferers. However, before using this drug, patients need to be sure about the side effects that may occur. Speridon Plus (Risperidone) can also be used for treating other disorders or as a complementary drug.

Speridon Plus warnings

In order to prescribe the correct dosage, your doctor needs to know details about your past and present medical conditions. Inform your doctor during this preliminary consultation if you suffer from any of the following diseases:

Aspiration pneumonia;

Blood circulation problems;

Bowel blockage;

Brain tumors;

Breast Cancer;

Cardiac or blood vessel problems;

Dehydration;

Dementia;

Diabetes or family history of diabetes;

Difficulty swallowing;

Drug abuse problems in the past;

Epilepsy;

Hearing impairment;

Inflammatory Bowel Disease;

Kidney disease;

Liver disease;

Parkinson's disease;

Phenylketonuria;

Poor WBC count;

Reye's syndrome.

Listed in the FDA pregnancy category C, doctors and researchers are not sure as to whether this bipolar medication can cause serious damage to the growing foetus or not, but the possibility cannot be ruled out. It is assumed that Speridon Plus (Risperidone) may pass into breast milk and harm a nursing baby. If pregnant or nursing it is recommended to bring this issue up with your physician before taking this medication. So far, this drug has not been tested on children and older patients, but this drug can be dangerous for older patients as it increases the likelihood of having strokes and ischemic attacks. So far no studies have been done on children.

The bipolar medication may not work in proper harmony with all other drugs. You should inform your doctor if you are already taking any of the following drugs before he prescribes Speridon Plus (Risperidone) Zydus Pharmaceuticals: Alcohol; Anafranil; Antihypertensives; Anzemet; Asendin; Atamet; Avelox; Aventyl; Betapace; Biaxin; Central nervous system (CNS) depressants; Clozaril; Cordarone; Covert; Dopar; Elavil; E-mycin; Epitol; Geodon; Haldol; Halfan; Imitrex; Inapsine; Lariam; Larodopa; Larodopa; Levaquin; Mellaril; Mirapex; Norpace; Norpramin; Norpramin; Orap; Orlaam; Parlodel; Paxil; Permax; Procainbid; Pronestyl; Propulsid; Prozac; Quinaglute; Quinidex; Requip; Rythmol; Sarafem; Serentil; Sinemet; Sinequan; Sorine; Surmontil; Tegretol; Tequin; Thorazine; Tikosyn; Tofranil; Trisenox; Vascor; Vivactil; Zofran; Zomig.

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Speridon Plus side effects

Intake of bipolar medication may cause serious allergic reactions. Breathing trouble, a closed throat, swollen lips, tongue or face are the most serious. Side effects like high body temperature, perspiration, muscle cramp, logical confusion, fluctuating heartbeat and so on associated with Neuroleptic Malignant Syndrome (NMS) may also be a problem. Don't ignore these side effects as it may have serious consequences. Immediately consult your doctor if these effects occur.

Individuals who use Speridon Plus (Risperidone) may experience side effects such as:

Vomiting

Muscle pain in the face and neck

Dizziness

Pacing heart beat

Speech distortion

Pain when swallowing

Excessive restlessness

These side effects are common but less harmful.

Side effects like sleeping disorders, hampered sight, headaches, sudden weight gain, loss of bladder control, pale skin, and fatigue are rare but do occur.

Speridon Plus overdose

It is imperative to consult a physician to be prescribed the correct dosing schedule. So far no serious cases of Speridon Plus (Risperidone) overdose have been reported. An overdose of the drug may not lead to death but it could be the cause of fatal disorders. The symptoms of an overdose may include:

Drowsiness

A pulsating heart rate

Sudden unconsciousness

Sweating

If you suspect that an overdose has occurred, consult your physician immediately.

On the other hand, missing a dose of this bipolar medication is not harmful. It is better to skip the missed dose completely in order to avoid the risk of overdose and see a doctor as soon as possible.

Speridon Plus usage guidelines

Rely on your doctor for the right usage guidelines. Normally this bipolar medication is taken with a glass of water. The tablet form should never be chewed. It is necessary to be very careful while driving, operating machinery or performing other hazardous activities after taking this drug. It is also recommended not to imbibe alcohol while using this medication, as the combination could be fatal. Keep the medication away from direct heat and sunlight. Also, Speridon Plus (Risperidone) should never be mixed with tea, coffee or cola. Intake of this bipolar medication should not be stopped suddenly without consulting a doctor. Speridon Plus (Risperidone) should be stored at room temperature for best results.

Trihexyphenidyl:


INDICATIONS AND USAGE

Speridon Plus (Trihexyphenidyl) HCl tablets are indicated as an adjunct in the treatment of all forms of parkinsonism (postencephalitic, arteriosclerotic, and idiopathic). It is often useful as adjuvant therapy when treating these forms of parkinsonism with levodopa. Additionally, it is indicated for the control of extrapyramidal disorders caused by central nervous system drugs such as the dibenzoxazepines, phenothiazines, thioxanthenes, and butyrophenones.

WARNINGS

Patients to be treated with Speridon Plus (Trihexyphenidyl) HCl should have a gonioscope evaluation and close monitoring of intraocular pressures at regular periodic intervals.

PRECAUTIONS

Although Speridon Plus (Trihexyphenidyl) HCl is not contraindicated for patients with cardiac, liver, or kidney disorders, or with hypertension, such patients should be maintained under close observation.

Since the use of Speridon Plus (Trihexyphenidyl) HCl may, in some cases, continue indefinitely and since it has atropine-like properties, patients should be subjected to constant and careful long-term observation to avoid allergic and other untoward reactions. Inasmuch as Speridon Plus (Trihexyphenidyl) HCl possesses some parasympatholytic activity, it should be used with caution in patients with glaucoma, obstructive disease of the gastrointestinal or genitourinary tracts, and in elderly males with possible prostatic hypertrophy. Geriatric patients, particularly over the age of 60, frequently develop increased sensitivity to the actions of drugs of this type, and hence, require strict dosage regulation. Incipient glaucoma may be precipitated by parasympatholytic drugs such as Speridon Plus (Trihexyphenidyl) HCl.

Tardive dyskinesia may appear in some patients on long-term therapy with antipsychotic drugs or may occur after therapy with these drugs has been discontinued. Antiparkinsonism agents do not alleviate the symptoms of tardive dyskinesia and, in some instances, may aggravate them. However, parkinsonism and tardive dyskinesia often coexist in patients receiving chronic neuroleptic treatment, and anticholinergic therapy with Speridon Plus (Trihexyphenidyl) HCl may relieve some of these parkinsonism symptoms.

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ADVERSE REACTIONS

Minor side effects, such as dryness of the mouth, blurring of vision, dizziness, mild nausea or nervousness, will be experienced by 30 to 50 percent of all patients. These sensations, however, are much less troublesome with Speridon Plus (Trihexyphenidyl) HCl than with belladonna alkaloids and are usually less disturbing than unalleviated parkinsonism. Such reactions tend to become less pronounced, and even to disappear, as treatment continues. Even before these reactions have remitted spontaneously, they may often be controlled by careful adjustment of dosage form, amount of drug, or interval between doses.

Isolated instances of suppurative parotitis secondary to excessive dryness at the mouth, skin rashes, dilatation of the colon, paralytic ileus, and certain psychiatric manifestations such as delusions and hallucinations, plus one doubtful case of paranoia all of which may occur with any of the atropine-like drugs, have been reported rarely with Speridon Plus (Trihexyphenidyl) hydrochloride.

Patients with arteriosclerosis or with a history of idiosyncrasy to other drugs may exhibit reactions of mental confusion, agitation, disturbed behavior, or nausea and vomiting. Such patients should be allowed to develop a tolerance through the initial administration of a small dose and gradual increase in dose until an effective level is reached. If a severe reaction should occur, administration of the drug should be discontinued for a few days and then resumed at a lower dosage. Psychiatric disturbances can result from indiscriminate use (leading to overdosage) to sustain continued euphoria.

Potential side effects associated with the use of any atropine-like drugs include constipation, drowsiness, urinary hesitancy or retention, tachycardia, dilation of the pupil, increased intraocular tension, weakness, vomiting, and headache.

The occurrence of angle-closure glaucoma due to long-term treatment with Speridon Plus (Trihexyphenidyl) has been reported.

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DOSAGE AND ADMINISTRATION

Dosage should be individualized. The initial dose should be low and then increased gradually, especially in patients over 60 years of age. Whether Speridon Plus HCl may best be given before or after meals should be determined by the way the patient reacts. Postencephalitic patients, who are usually more prone to excessive salivation, may prefer to take it after meals and may, in addition, require small amounts of atropine which, under such circumstances, is sometimes an effective adjuvant. If Speridon Plus (Trihexyphenidyl) HCl tends to dry the mouth excessively, it may be better to take it before meals, unless it causes nausea. If taken after meals, the thirst sometimes induced can be allayed by mint candies, chewing gum or water.

Speridon Plus (Trihexyphenidyl) HCl in Idiopathic Parkinsonism

As initial therapy for parkinsonism, 1 mg of Speridon Plus (Trihexyphenidyl) in tablet form may be administered the first day. The dose may then be increased by 2 mg increments at intervals of three to five days, until a total of 6 to 10 mg is given daily. The total daily dose will depend upon what is found to be the optimal level. Many patients derive maximum benefit from this daily total of 6 to 10 mg, but some patients, chiefly those in the postencephalitic group, may require a total daily dose of 12 to 15 mg.

Speridon Plus HCl in Drug-Induced Parkinsonism

The size and frequency of dose of Speridon Plus (Trihexyphenidyl) HCl needed to control extrapyramidal reactions to commonly employed tranquilizers, notably the phenothiazines, thioxanthenes, and butyrophenones, must be determined empirically. The total daily dosage usually ranges between 5 and 15 mg, although, in some cases, these reactions have been satisfactorily controlled on as little as 1 mg daily. It may be advisable to commence therapy with a single 1 mg dose. If the extrapyramidal manifestations are not controlled in a few hours, the subsequent doses may be progressively increased until satisfactory control is achieved. Satisfactory control may sometimes be more rapidly achieved by temporarily reducing the dosage of the tranquilizer on instituting Speridon Plus (Trihexyphenidyl) HCl therapy and then adjusting dosage of both drugs until the desired ataractic effect is retained without onset of extrapyramidal reactions.

It is sometimes possible to maintain the patient on a reduced Speridon Plus (Trihexyphenidyl) HCl dosage after the reactions have remained under control for several days. Instances have been reported in which these reactions have remained in remission for long periods after Speridon Plus (Trihexyphenidyl) HCl therapy was discontinued.

Concomitant Use of Speridon Plus HCl with Levodopa

When Speridon Plus (Trihexyphenidyl) HCl is used concomitantly with levodopa, the usual dose of each may need to be reduced. Careful adjustment is necessary, depending on side effects and degree of symptom control. Speridon Plus (Trihexyphenidyl) HCl dosage of 3 to 6 mg daily, in divided doses, is usually adequate.

Concomitant Use of Speridon Plus HCl with Other Parasympathetic Inhibitors

Speridon Plus (Trihexyphenidyl) HCl may be substituted, in whole or in part, for other parasympathetic inhibitors. The usual technique is partial substitution initially, with progressive reduction in the other medication as the dose of Speridon Plus (Trihexyphenidyl) HCl is increased.

The total daily intake of Speridon Plus (Trihexyphenidyl) HCl tablets is tolerated best if divided into 3 doses and taken at mealtimes. High doses (>10 mg daily) may be divided into 4 parts, with 3 doses administered at mealtimes and the fourth at bedtime.

HOW SUPPLIED

Speridon Plus (Trihexyphenidyl) HCl tablets are available as follows:

2 mg – round, flat, scored, white tablets; debossed "5971" above the score and "V" below the score. Available in bottles of 100, 500 and 1000.

5 mg – round, flat, scored, white tablets; debossed "5972" above the score and "V" below the score. Available in bottles of 100, 500, and 1000.

Dispense in a tight, light-resistant container as defined in the USP.

Store at 20° to 25°C (68° to 77°F).

Manufactured for:

QUALITEST PHARMACEUTICALS

Huntsville, AL 35811

8181446

Rev 2/08

R2

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Speridon Plus pharmaceutical active ingredients containing related brand and generic drugs:

Active ingredient is the part of the drug or medicine which is biologically active. This portion of the drug is responsible for the main action of the drug which is intended to cure or reduce the symptom or disease. The other portions of the drug which are inactive are called excipients; there role is to act as vehicle or binder. In contrast to active ingredient, the inactive ingredient's role is not significant in the cure or treatment of the disease. There can be one or more active ingredients in a drug.


Speridon Plus available forms, composition, doses:

Form of the medicine is the form in which the medicine is marketed in the market, for example, a medicine X can be in the form of capsule or the form of chewable tablet or the form of tablet. Sometimes same medicine can be available as injection form. Each medicine cannot be in all forms but can be marketed in 1, 2, or 3 forms which the pharmaceutical company decided based on various background research results.
Composition is the list of ingredients which combinedly form a medicine. Both active ingredients and inactive ingredients form the composition. The active ingredient gives the desired therapeutic effect whereas the inactive ingredient helps in making the medicine stable.
Doses are various strengths of the medicine like 10mg, 20mg, 30mg and so on. Each medicine comes in various doses which is decided by the manufacturer, that is, pharmaceutical company. The dose is decided on the severity of the symptom or disease.


Speridon Plus destination | category:

Destination is defined as the organism to which the drug or medicine is targeted. For most of the drugs what we discuss, human is the drug destination.
Drug category can be defined as major classification of the drug. For example, an antihistaminic or an antipyretic or anti anginal or pain killer, anti-inflammatory or so.


Speridon Plus Anatomical Therapeutic Chemical codes:

A medicine is classified depending on the organ or system it acts [Anatomical], based on what result it gives on what disease, symptom [Therapeutical], based on chemical composition [Chemical]. It is called as ATC code. The code is based on Active ingredients of the medicine. A medicine can have different codes as sometimes it acts on different organs for different indications. Same way, different brands with same active ingredients and same indications can have same ATC code.


Speridon Plus pharmaceutical companies:

Pharmaceutical companies are drug manufacturing companies that help in complete development of the drug from the background research to formation, clinical trials, release of the drug into the market and marketing of the drug.
Researchers are the persons who are responsible for the scientific research and is responsible for all the background clinical trials that resulted in the development of the drug.


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References

  1. Dailymed."RISPERIDONE TABLET, FILM COATED [BRYANT RANCH PREPACK]". https://dailymed.nlm.nih.gov/dailym... (accessed August 28, 2018).
  2. Dailymed."RISPERIDONE: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailym... (accessed August 28, 2018).
  3. "trihexyphenidyl". https://pubchem.ncbi.nlm.nih.gov/co... (accessed August 28, 2018).

Frequently asked Questions

Can i drive or operate heavy machine after consuming Speridon Plus?

Depending on the reaction of the Speridon Plus after taken, if you are feeling dizziness, drowsiness or any weakness as a reaction on your body, Then consider Speridon Plus not safe to drive or operate heavy machine after consumption. Meaning that, do not drive or operate heavy duty machines after taking the capsule if the capsule has a strange reaction on your body like dizziness, drowsiness. As prescribed by a pharmacist, it is dangerous to take alcohol while taking medicines as it exposed patients to drowsiness and health risk. Please take note of such effect most especially when taking Primosa capsule. It's advisable to consult your doctor on time for a proper recommendation and medical consultations.

Is Speridon Plus addictive or habit forming?

Medicines are not designed with the mind of creating an addiction or abuse on the health of the users. Addictive Medicine is categorically called Controlled substances by the government. For instance, Schedule H or X in India and schedule II-V in the US are controlled substances.

Please consult the medicine instruction manual on how to use and ensure it is not a controlled substance.In conclusion, self medication is a killer to your health. Consult your doctor for a proper prescription, recommendation, and guidiance.

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Review

sdrugs.com conducted a study on Speridon Plus, and the result of the survey is set out below. It is noteworthy that the product of the survey is based on the perception and impressions of the visitors of the website as well as the views of Speridon Plus consumers. We, as a result of this, advice that you do not base your therapeutic or medical decisions on this result, but rather consult your certified medical experts for their recommendations.

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The information was verified by Dr. Rachana Salvi, MD Pharmacology

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