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DRUGS & SUPPLEMENTS
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Skelan Protect
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Skelan Protect uses
Skelan Protect consists of Naproxen Sodium, Omeprazole.Naproxen Sodium:
Skelan Protect information
Skelan Protect (Naproxen Sodium) is an anti-inflammatory non-steroidal anti-inflammatory (NSAID) medicine. Skelan Protect (Naproxen Sodium) Actavis's actions help reduce the chemicals found in the patient's organism that are usually responsible for the triggering of inflammation and pain.
Skelan Protect indications
Skelan Protect (Naproxen Sodium) is a drug normally prescribed in the treatment of pain, stiffness or inflammation that are usually triggered by medical disorders such as Gout, Osteoarthritis, menstruation abdominal cramps, rheumatoid arthritis, ankylosing spondylitis, injury, buritis and tendonitis.
Skelan Protect (Naproxen Sodium) could also be prescribed in the treatment of other medical conditions that have not been mentioned here.
Skelan Protect warnings
While the patient is following a treatment with Skelan Protect (Naproxen Sodium) Actavis, he or she should avoid consuming big amounts of alcohol. It is recommended that alcohol drinks should be entirely avoided as they increase the danger of stomach bleeding. Therefore, if the patient is consuming more than 3 bottles of different alcoholic beverages he or she might not be allowed to start a treatment with Skelan Protect (Naproxen Sodium) Actavis.
Skelan Protect (Naproxen Sodium) can lead to drowsiness and dizziness. If you are following a treatment with this drug you should be careful while performing actions that require mental and physical alertness. The treatment with Skelan Protect (Naproxen Sodium) should be carefully monitored in the case of patients suffering from any of the next medical disorders:
Allergic reactions to Aspirin (or any other NSAIDs)
Bleeding disorder
Liver problems
High blood pressure
Heart failure
Congestive heart disease
Fluid retention
Ulcer
Kidney disease
Stomach bleeding
If you are suffering from any of these medical disorders you might not be allowed to start a treatment with Skelan Protect (Naproxen Sodium) Actavis.
Skelan Protect (Naproxen Sodium) is a Category B FDA pregnancy drug. Therefore it is not considered to be harmful to an unborn child. However, if you are pregnant, consult with your doctor before starting a treatment with Skelan Protect (Naproxen Sodium) Actavis. Skelan Protect (Naproxen Sodium) (one of Skelan Protect (Naproxen Sodium) Actavis's main ingredients) can pass into breast milk. If you are nursing an infant you should consult with your doctor before starting a treatment with Skelan Protect (Naproxen Sodium) Actavis.
Skelan Protect intake guidelines
Skelan Protect (Naproxen Sodium) ought to be taken in just like your doctor told you to. Do not disobey the physician's instructions.
You should accompany each dose of the drug with a glass of water (from 6 to 8 ounces of liquid). Do not take Skelan Protect (Naproxen Sodium) on an empty stomach as it can cause stomach upset. Do not stop your treatment with this drug without your doctor's consent even if you do not feel better after a few days of treatment.
Skelan Protect dosage
Ask your doctor to calculate the dose of Skelan Protect (Naproxen Sodium) that suits you best. The correct dosage varies from one person to another, as it depends on a couple of factors.
Skelan Protect overdose
Reported Skelan Protect (Naproxen Sodium) overdose symptoms are:
Nausea
Excessive sweating
Vomiting
Tingling sensation in legs and arms
Blurred vision
No or little urine production
Shallow and slow breathing
Stomach pains
Numbness
Ringing in the ears
If you are experiencing any of the symptoms listed here, you are in need of medical attention (inform your doctor immediately).
Skelan Protect missed dose
Skelan Protect (Naproxen Sodium) can be taken in when you need it or on a regular basis. If you are following a treatment with Skelan Protect (Naproxen Sodium) Actavis, try not to miss any of your doses. If you happen to miss one take it as soon as possible. If it is almost time for another dose, skip the one that you have missed and continue with your regular schedule. You should not take in a double dose of this drug.
Skelan Protect side effects
Very serious side effects of Skelan Protect (Naproxen Sodium) are bloody vomit or bloody stools.
Other dangerous side effects of Skelan Protect (Naproxen Sodium) are:
Allergic reactions (difficulty while breathing, throat closing, hives, swelling of mouth, lips and tongue).
Tingling
Muscle cramps
Mouth ulcers
Numbness
Fluid retention
Jaundice
Ringing in the ears
Stomach cramps or stomach upsets, indigestion or heartburn
Other side effects of the drug are:
Dizziness
Nausea
Headache
Fatigue
Depression
Dry mouth
Weakness
Irregular menstruation
There are other mild side effects that can also occur if you are taking Skelan Protect (Naproxen Sodium) Actavis. Inform your physician if you feel anything disturbing or unusual.
Skelan Protect drug reactions
You should inform your doctor if you are following a treatment with any of the drugs listed here:
Aspirin
NSAIDs
Cold and cough medicines
Steroids (like prednisone)
Anti coagulants
Insulin
Lithium
Probenecid
Pepto-Bismol
If you are taking any of these drugs you may not be allowed to start taking Skelan Protect (Naproxen Sodium) Actavis. Ask for your doctor's advice before you start a treatment with this drug.
Omeprazole:
Pharmacological action
Skelan Protect is an inhibitor of H+ K+ ATPase. This medication inhibits the activity of H+-K+-ATPase in gastric parietal cells and thus blocks the final stage of hydrochloric acid secretion. This leads to a reduction in basal and stimulated secretion, regardless of the nature of the stimulus. Due to the reduction of acid secretion Skelan Protect (Omeprazole) reduces or normalizes the effects of acid in the esophagus in patients with reflux esophagitis.
Skelan Protect (Omeprazole) has a bactericidal effect on Helicobacter pylori. Eradication of H. pylori when Skelan Protect (Omeprazole) used with antibiotics allows to quickly arrest the symptoms, to take a high degree of healing of damaged mucosa and persistent long-term remission and reduce the likelihood of bleeding from the gastrointestinal tract.
Pharmacokinetics
After oral administration Skelan Protect (Omeprazole) is rapidly absorbed from the gastrointestinal tract. This drug penetrates the parietal cells of gastric mucosa. Plasma protein binding is about 95% (predominantly albumin). Skelan Protect (Omeprazole) is biotransformed in the liver. Excreted by the kidneys - 72-80%, in the faeces - about 20%. T1/2 is 0.5-1 h. In patients with chronic liver diseases T1/2 increases up to 3 hours.
Why is Skelan Protect prescribed?
Gastric ulcer and duodenal ulcer in acute phase (including associated with Helicobacter pylori), reflux esophagitis, Zollinger-Ellison syndrome, erosive and ulcerative lesions of gastric and duodenal ulcers associated with taking NSAIDs.
Dosage and administration
The dosing regimen of Skelan Protect is individual. When this medication is administered orally of the single dose is 20-40 mg. The daily dose is 20-80 mg, the frequency of use is 1-2 times / day. The duration of treatment is 2-8 weeks.
Skelan Protect (Omeprazole) side effects, adverse reactions
Digestive system: rarely - nausea, diarrhea, constipation, abdominal pain, flatulence.
CNS: rarely - headache, dizziness, weakness.
Hemopoietic system: in some cases - anemia, eosinopenia, neutropenia, thrombocytopenia.
Urinary system: in some cases - hematuria, proteinuria.
Musculoskeletal system: in some cases - arthralgia, muscle weakness, myalgia.
Allergic reactions: rarely - skin rash.
Skelan Protect contraindications
Chronic liver disease (including in history), hypersensitivity to Skelan Protect (Omeprazole).
Using during pregnancy and breastfeeding
In the absence of clinical experience with Skelan Protect it is not recommended to use this drug during pregnancy. If necessary to use during Skelan Protect (Omeprazole) lactation it should been solve the issue of termination of breastfeeding.
Category effects on the fetus by FDA - C.
Special instructions
Before the treatment with Skelan Protect (Omeprazole) it is necessary to exclude the possibility of a malignant process (especially gastric ulcer) because Skelan Protect (Omeprazole) treatment can mask symptoms and delay the correct diagnosis.
Therapy with Skelan Protect (Omeprazole) may affects results of laboratory studies of liver and gastrin concentrations in blood plasma.
Due to lack of experience in clinical application of Skelan Protect (Omeprazole) this medicine is not recommended for children.
Skelan Protect drug interactions
This medication alters the bioavailability of any drug, absorption depends on pH (ketoconazole, iron salts, etc.). Skelan Protect (Omeprazole) slows down the elimination of drugs metabolized in the liver by microsomal oxidation (warfarin, diazepam, phenytoin, etc.).
Skelan Protect (Omeprazole) enhances the action of coumarin and diphenine, does not change - NSAIDs. This drug increases (relative) the concentration of clarithromycin in the blood; may increases the leukopenic and thrombocytopenic effects of depressants hematopoiesis drugs. Substance for intravenous infusion is compatible only with saline and dextrose (using other solvents may decrease the stability of Skelan Protect (Omeprazole) due to changes in pH of infusion medium).
Skelan Protect in case of emergency / overdose
Symptoms: dry mouth, nausea, blurred vision, headache, increased sweating, flushing, tachycardia, drowsiness, confusion.
Treatment: symptomatic, dialysis is ineffective.
Skelan Protect pharmaceutical active ingredients containing related brand and generic drugs:
Skelan Protect available forms, composition, doses:
Composition is the list of ingredients which combinedly form a medicine. Both active ingredients and inactive ingredients form the composition. The active ingredient gives the desired therapeutic effect whereas the inactive ingredient helps in making the medicine stable.
Doses are various strengths of the medicine like 10mg, 20mg, 30mg and so on. Each medicine comes in various doses which is decided by the manufacturer, that is, pharmaceutical company. The dose is decided on the severity of the symptom or disease.