Selegiline

What are the side effects you encounter while taking this medicine?
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Selegiline uses


Pharmacological action

Selegiline is an almost near-to-white crystalline powder that is round, convex, scored, and uncoated tablet. Selegiline is freely soluble in water. Selegiline is used to treat Parkinson's disease, a disease associated with low levels of dopamine in your brain. The question how really Selegiline works is not known but it is believed to prevent the breakdown of dopamine in your brain. After levedopa or carbidopa therapy begins to deteriorate, Selegiline is usually added to a treatment regimen.

Why is Selegiline prescribed?

Selegiline is mainly used to handle the stiffness, tremors, spasms, and poor muscle control of Parkinson's disease. It can be used as monotherapy in the early phases of the disease and as adjunctive therapy with levodopa. Selegiline is also used to handle some muscular conditions that are caused by certain drugs such as Chlorpromazine, Fluphenazine (Prolixin), Perphenazine (Trilafon), and other more. Selegiline can also be used to some purposes not stated here.

Dosage and administration

Follow the prescription of your doctor if you are to take Selegiline Pharmaniaga. You may also ask your pharmacist or nurse about things you do not understand. Take each dose with full glass of water. Follow your doctor's prescription. This medication is usually taken twice a day, at breakfast and lunch. Do not take larger dosage than are given. It will have a greater and sever effect on you.

Obtain the dosage for this medicine from your doctor. Dosage may vary from person to person.

If you missed a dose of this drug immediately take the missed dose as soon as you remember but if it is almost time for the nest dose, skip the missed one and take the subsequent dose according to schedule. It is important to remember not to take a double dose of this medicine.

Selegiline side effects

Severe side effects of Selegiline may include the following:

  • allergic reactions such as difficulty in breathing; closing of throat; swelling of lips, tongue, or face; or hives)
  • severe headaches
  • restlessness, agitation, or irritability
  • sweating
  • convulsions
  • uncontrollable or irregular movements
  • dizziness or drowsiness
  • nausea, abdominal pain, or diarrhea
  • insomnia or vivid dreams
  • mild confusion, agitation, or anxiety
  • mild headache
  • dry mouthOther side effects may also occur other than the above mentioned. Inform your doctor if you feel anything unusual.

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    Selegiline contraindications

    This medication is contraindicated in patients with a known hypersensitivity to this drug.

    Selegiline is contraindicated for use with meperidine. This contraindication is often extended to other opioids.

    Special instructions

    Selegiline belongs in the FDA pregnancy category C. It is unknown whether Selegiline will harm an unborn baby. It is more advisable for you to consult first your doctor before taking this drug. Also, it is unknown whether Selegiline will harm a nursing infant. Still, consult your doctor first before taking this medicine if you are breast-feeding a baby. Use caution when driving, operating machinery, or performing other hazardous activities. Selegiline should be given with care to patients with the following:

  • peptic or duodenal ulcer
  • labile hypertension
  • cardiac arrhythmias
  • serious angina pectoris or psychosis

    Selegiline drug interactions

    Selegiline may be dangerous if taken with the following drugs:

  • Flouxetine
  • Meperidine (Demerol)Other drugs not mentioned here may also interact with Selegiline. Consult your doctor and pharmacist before having any prescription or over-the-counter medicines.

    Selegiline in case of emergency / overdose

    Overdose of Selegiline may be characterized with: excitement; irritability; nervousness; insomnia; dizziness; severe headache; hallucinations; weakness; sweating; seizures; drowsiness; fainting; hypotension; hypertension; hyperactivity; agitation; vascular collapse; rapid and irregular pulse; precordial pain; respiratory depression and failure; hyperpyrexia.

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    Selegiline pharmaceutical active ingredients containing related brand and generic drugs:

    Active ingredient is the part of the drug or medicine which is biologically active. This portion of the drug is responsible for the main action of the drug which is intended to cure or reduce the symptom or disease. The other portions of the drug which are inactive are called excipients; there role is to act as vehicle or binder. In contrast to active ingredient, the inactive ingredient's role is not significant in the cure or treatment of the disease. There can be one or more active ingredients in a drug.


    Selegiline available forms, composition, doses:

    Form of the medicine is the form in which the medicine is marketed in the market, for example, a medicine X can be in the form of capsule or the form of chewable tablet or the form of tablet. Sometimes same medicine can be available as injection form. Each medicine cannot be in all forms but can be marketed in 1, 2, or 3 forms which the pharmaceutical company decided based on various background research results.
    Composition is the list of ingredients which combinedly form a medicine. Both active ingredients and inactive ingredients form the composition. The active ingredient gives the desired therapeutic effect whereas the inactive ingredient helps in making the medicine stable.
    Doses are various strengths of the medicine like 10mg, 20mg, 30mg and so on. Each medicine comes in various doses which is decided by the manufacturer, that is, pharmaceutical company. The dose is decided on the severity of the symptom or disease.

    Price
    Apo-Selegiline 5 mg Tablet1.33 USD
    Capsules; Oral; Selegiline Hydrochloride 5 mg
    Eldepryl 30 5 mg capsule Box89.55 USD
    Emsam 12 mg/24 hours patch20.1 USD
    Emsam 30 12 mg/24hr Patches Box627.1 USD
    Emsam 30 6 mg/24hr Patches Box627.1 USD
    Emsam 30 9 mg/24hr Patches Box627.1 USD
    Emsam 6 mg/24 hours patch20.1 USD
    Emsam 9 mg/24 hours patch20.1 USD
    Mylan-Selegiline 5 mg Tablet1.33 USD
    Novo-Selegiline 5 mg Tablet1.33 USD
    Nu-Selegiline 5 mg Tablet1.33 USD
    Pms-Selegiline 5 mg Tablet1.33 USD
    Selegiline HCl 5 mg capsule2.4 USD
    Selegiline hcl 5 mg tablet2.1 USD
    Selegiline hcl powder127.3 USD
    Tablets; Oral; Selegiline Hydrochloride 5 mg
    Zelapar 1.25 mg odt tablet8.33 USD

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    Selegiline destination | category:

    Destination is defined as the organism to which the drug or medicine is targeted. For most of the drugs what we discuss, human is the drug destination.
    Drug category can be defined as major classification of the drug. For example, an antihistaminic or an antipyretic or anti anginal or pain killer, anti-inflammatory or so.


    Selegiline Anatomical Therapeutic Chemical codes:

    A medicine is classified depending on the organ or system it acts [Anatomical], based on what result it gives on what disease, symptom [Therapeutical], based on chemical composition [Chemical]. It is called as ATC code. The code is based on Active ingredients of the medicine. A medicine can have different codes as sometimes it acts on different organs for different indications. Same way, different brands with same active ingredients and same indications can have same ATC code.


    Selegiline pharmaceutical companies:

    Pharmaceutical companies are drug manufacturing companies that help in complete development of the drug from the background research to formation, clinical trials, release of the drug into the market and marketing of the drug.
    Researchers are the persons who are responsible for the scientific research and is responsible for all the background clinical trials that resulted in the development of the drug.


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    References

    1. Dailymed."EMSAM (SELEGILINE) PATCH [MYLAN SPECIALTY L.P.]". https://dailymed.nlm.nih.gov/dailym... (accessed August 28, 2018).
    2. Dailymed."SELEGILINE HYDROCHLORIDE TABLET [MYLAN PHARMACEUTICALS INC.]". https://dailymed.nlm.nih.gov/dailym... (accessed August 28, 2018).
    3. Dailymed."SELEGILINE: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailym... (accessed August 28, 2018).

    Frequently asked Questions

    Can i drive or operate heavy machine after consuming Selegiline?

    Depending on the reaction of the Selegiline after taken, if you are feeling dizziness, drowsiness or any weakness as a reaction on your body, Then consider Selegiline not safe to drive or operate heavy machine after consumption. Meaning that, do not drive or operate heavy duty machines after taking the capsule if the capsule has a strange reaction on your body like dizziness, drowsiness. As prescribed by a pharmacist, it is dangerous to take alcohol while taking medicines as it exposed patients to drowsiness and health risk. Please take note of such effect most especially when taking Primosa capsule. It's advisable to consult your doctor on time for a proper recommendation and medical consultations.

    Is Selegiline addictive or habit forming?

    Medicines are not designed with the mind of creating an addiction or abuse on the health of the users. Addictive Medicine is categorically called Controlled substances by the government. For instance, Schedule H or X in India and schedule II-V in the US are controlled substances.

    Please consult the medicine instruction manual on how to use and ensure it is not a controlled substance.In conclusion, self medication is a killer to your health. Consult your doctor for a proper prescription, recommendation, and guidiance.

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    Review

    sdrugs.com conducted a study on Selegiline, and the result of the survey is set out below. It is noteworthy that the product of the survey is based on the perception and impressions of the visitors of the website as well as the views of Selegiline consumers. We, as a result of this, advice that you do not base your therapeutic or medical decisions on this result, but rather consult your certified medical experts for their recommendations.

    Visitor reports

    Visitor reported useful

    No survey data has been collected yet

    Visitor reported side effects

    No survey data has been collected yet

    Visitor reported price estimates

    No survey data has been collected yet

    One visitor reported frequency of use

    How often in a day do you take the medicine?
    Are you taking the Selegiline drug as prescribed by the doctor?

    Few medications can be taken Twice in a day more than prescribed when the doctor's advice mentions the medicine can be taken according to frequency or severity of symptoms. Most times, be very careful and clear about the number of times you are taking the medication. The report of sdrugs.com website users about the frequency of taking the drug Selegiline is mentioned below.
    Visitors%
    Twice in a day1
    100.0%

    Visitor reported doses

    No survey data has been collected yet

    Visitor reported time for results

    No survey data has been collected yet

    Visitor reported administration

    No survey data has been collected yet

    Visitor reported age

    No survey data has been collected yet

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    The information was verified by Dr. Rachana Salvi, MD Pharmacology

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