Rinomar

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Rinomar uses

Rinomar consists of Cinnarizine, Phenylpropanolamine Hydrochloride.

Cinnarizine:


Pharmacological action

Rinomar is a calcium channel blocker class IV with a predominant effect on the brain vessels, a derivative of piperazine. This medication improves cerebral, coronary and peripheral circulation. Rinomar (Cinnarizine) violates the entrance of calcium ions into vascular smooth muscle cells. This drug lowers the tone of arteriolar smooth muscle, decreases the vasoconstrictor response to biogenic substances (epinephrine, norepinephrine, bradykinin). Rinomar (Cinnarizine) reduces the excitability of the vestibular apparatus. In patients with impaired peripheral circulation Rinomar (Cinnarizine) improves blood flow and potentiates postischemic hyperemia. This medicine increases the resistance of tissue to hypoxia.

Pharmacokinetics

After oral administration Rinomar (Cinnarizine) is absorbed from the gastrointestinal tract, Cmax in plasma is reached after 1-4 h. The plasma protein binding is 91%. This medication is metabolized. T1/2 is 3-6 hours. Rinomar (Cinnarizine) is eliminated through the intestine largely unchanged, with the urine - mainly in the form of metabolites.

Why is Rinomar prescribed?

Ischemic attacks (including the residual effects after a stroke). Labyrinth disorders (including for maintenance therapy for dizziness, tinnitus, nystagmus, nausea and vomiting of labyrinth origin). Motion sickness (as a prophylactic agent). Prophylaxis of migraine. Meniere's disease. Prevention and treatment of disorders of peripheral circulation - atherosclerosis, thromboangiitis obliterans, Raynaud's disease, diabetic angiopathy, acrocyanosis.

Dosage and administration

The dosage regimen is individual. Rinomar is taken orally in 25-50-75 mg 3 times / day after a meal. If necessary, the treatment can begin with half the dose and gradually increasing. To achieve the optimal therapeutic effect is used continuously for several months.

Rinomar (Cinnarizine) side effects, adverse reactions

Digestive system: dyspepsia, dry mouth, rarely - cholestatic jaundice.

CNS: headache, drowsiness; in elderly patients in long-term use may be extrapyramidal symptoms, depression.

Allergic reactions: rarely - skin rash.

Other: weight gain, increased sweating, in rare cases - lupus-like syndrome, lichen planus.

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Rinomar contraindications

Hypersensitivity to Rinomar (Cinnarizine).

Using during pregnancy and breastfeeding

During pregnancy and lactation Rinomar (Cinnarizine) usage is possible only in exceptional cases, when the expected benefit to the mother far outweighs the potential risk to the fetus or infant.

Special instructions

Use Rinomar (Cinnarizine) with caution in patients with hypertension.

With prolonged use is recommended to perform control examination of liver, kidney, peripheral blood picture.

At the beginning of treatment you should refrain from potentially hazardous activities that require attention and speed of psychomotor reactions.

Rinomar drug interactions

When this drug applied simultaneously with:

- tricyclic antidepressants, hypnotics, drugs that have a sedative effect, alcohol, ethanol-containing medication increases the effects on the CNS.

- antihypertensive drugs increased hypotensive effect.

- nootropics, vasodilators - increases the action of nootropic drugs and vasodilators.

- phenylpropanolamine reduces sedation effect of Rinomar (Cinnarizine) Quality Pharmaceutical Laboratory.

Rinomar in case of emergency / overdose

Treatment: gastric lavage, taking activated charcoal, symptomatic therapy. There is no a specific antidote.

Phenylpropanolamine Hydrochloride:


Rinomar (Phenylpropanolamine Hydrochloride) has been withdrawn in Canada. In November 2000, the Food and Drug Administration (FDA) issued a public health advisory against the use of the drug.

Indication: For the treatment of nasal congestion, control of urinary incontinence, priapism and obesity.

Rinomar (Phenylpropanolamine Hydrochloride) (PPA), a sympathomimetic agent structurally similar to pseudoephedrine, is used to treat nasal congestion. Rinomar (Phenylpropanolamine Hydrochloride) is found in appetite suppressant formulations and with guaifenesinin in cough-cold formulations. In 2000, the FDA requested that all drug companies discontinue marketing products containing Rinomar (Phenylpropanolamine Hydrochloride), due to an increased risk of hemorrhagic stroke in women who used Rinomar (Phenylpropanolamine Hydrochloride).

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Rinomar pharmaceutical active ingredients containing related brand and generic drugs:

Active ingredient is the part of the drug or medicine which is biologically active. This portion of the drug is responsible for the main action of the drug which is intended to cure or reduce the symptom or disease. The other portions of the drug which are inactive are called excipients; there role is to act as vehicle or binder. In contrast to active ingredient, the inactive ingredient's role is not significant in the cure or treatment of the disease. There can be one or more active ingredients in a drug.


Rinomar available forms, composition, doses:

Form of the medicine is the form in which the medicine is marketed in the market, for example, a medicine X can be in the form of capsule or the form of chewable tablet or the form of tablet. Sometimes same medicine can be available as injection form. Each medicine cannot be in all forms but can be marketed in 1, 2, or 3 forms which the pharmaceutical company decided based on various background research results.
Composition is the list of ingredients which combinedly form a medicine. Both active ingredients and inactive ingredients form the composition. The active ingredient gives the desired therapeutic effect whereas the inactive ingredient helps in making the medicine stable.
Doses are various strengths of the medicine like 10mg, 20mg, 30mg and so on. Each medicine comes in various doses which is decided by the manufacturer, that is, pharmaceutical company. The dose is decided on the severity of the symptom or disease.


Rinomar destination | category:

Destination is defined as the organism to which the drug or medicine is targeted. For most of the drugs what we discuss, human is the drug destination.
Drug category can be defined as major classification of the drug. For example, an antihistaminic or an antipyretic or anti anginal or pain killer, anti-inflammatory or so.


Rinomar Anatomical Therapeutic Chemical codes:

A medicine is classified depending on the organ or system it acts [Anatomical], based on what result it gives on what disease, symptom [Therapeutical], based on chemical composition [Chemical]. It is called as ATC code. The code is based on Active ingredients of the medicine. A medicine can have different codes as sometimes it acts on different organs for different indications. Same way, different brands with same active ingredients and same indications can have same ATC code.


Rinomar pharmaceutical companies:

Pharmaceutical companies are drug manufacturing companies that help in complete development of the drug from the background research to formation, clinical trials, release of the drug into the market and marketing of the drug.
Researchers are the persons who are responsible for the scientific research and is responsible for all the background clinical trials that resulted in the development of the drug.


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References

  1. Dailymed."PROIN 75 (PHENYLPROPANOLAMINE HYDROCHLORIDE) TABLET, CHEWABLE [PEGASUS LABORATORIES, INC.]". https://dailymed.nlm.nih.gov/dailym... (accessed August 28, 2018).

Frequently asked Questions

Can i drive or operate heavy machine after consuming Rinomar?

Depending on the reaction of the Rinomar after taken, if you are feeling dizziness, drowsiness or any weakness as a reaction on your body, Then consider Rinomar not safe to drive or operate heavy machine after consumption. Meaning that, do not drive or operate heavy duty machines after taking the capsule if the capsule has a strange reaction on your body like dizziness, drowsiness. As prescribed by a pharmacist, it is dangerous to take alcohol while taking medicines as it exposed patients to drowsiness and health risk. Please take note of such effect most especially when taking Primosa capsule. It's advisable to consult your doctor on time for a proper recommendation and medical consultations.

Is Rinomar addictive or habit forming?

Medicines are not designed with the mind of creating an addiction or abuse on the health of the users. Addictive Medicine is categorically called Controlled substances by the government. For instance, Schedule H or X in India and schedule II-V in the US are controlled substances.

Please consult the medicine instruction manual on how to use and ensure it is not a controlled substance.In conclusion, self medication is a killer to your health. Consult your doctor for a proper prescription, recommendation, and guidiance.

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Review

sdrugs.com conducted a study on Rinomar, and the result of the survey is set out below. It is noteworthy that the product of the survey is based on the perception and impressions of the visitors of the website as well as the views of Rinomar consumers. We, as a result of this, advice that you do not base your therapeutic or medical decisions on this result, but rather consult your certified medical experts for their recommendations.

Visitor reports

One visitor reported useful

How is the drug Rinomar useful in reducing or relieving the symptoms? How useful is it?
According to the survey conducted by the website sdrugs.com, there are variable results and below are the percentages of the users that say the medicine is useful to them and that say it is not helping them much. It is not ideal to continue taking the medication if you feel it is not helping you much. Contact your healthcare provider to check if there is a need to change the medicine or if there is a need to re-evaluate your condition. The usefulness of the medicine may vary from patient to patient, depending on the other diseases he is suffering from and slightly depends on the brand name.
Visitors%
Useful1
100.0%

Visitor reported side effects

No survey data has been collected yet

Visitor reported price estimates

No survey data has been collected yet

Visitor reported frequency of use

No survey data has been collected yet

Visitor reported doses

No survey data has been collected yet

One visitor reported time for results

What is the time duration Rinomar drug must be taken for it to be effective or for it to reduce the symptoms?
Most chronic conditions need at least some time so the dose and the drug action gets adjusted to the body to get the desired effect. The stastistics say sdrugs.com website users needed 5 days to notice the result from using Rinomar drug. The time needed to show improvement in health condition after using the medicine Rinomar need not be same for all the users. It varies based on other factors.
Visitors%
5 days1
100.0%

Visitor reported administration

No survey data has been collected yet

Two visitors reported age

Visitors%
46-601
50.0%
> 601
50.0%

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The information was verified by Dr. Rachana Salvi, MD Pharmacology

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