DRUGS & SUPPLEMENTS

Prolutone

Name: Prolutone drug & pharmaceuticals. Available Forms, Doses, Prices
Creator: sdrugs.com
Published: 2021-11-11T10:10:10+00:00

How is the drug helping you?

Prolutone uses

Pharmacological action
Pharmacokinetics
Why is Prolutone prescribed?
Dosage and administration
Prolutone side effects, adverse reactions
Prolutone contraindications
Using during pregnancy and breastfeeding
Special instructions
Prolutone drug interactions
Prolutone reviews

Pharmacological action

Prolutone is a progestogen. This medication causes a transition in the endometrium of proliferative phase, called follicular hormone in the secretory phase, and after fertilization promotes its transition to a state necessary for the development of a fertilized egg. Prolutone reduces the excitability and contractility of the muscles of the uterus and fallopian tubes, stimulates the development of terminal elements of the breast. It has no androgenic activity. This drug has little effect on protein metabolism, promotes fat deposit and accumulation of glucose in the liver and reduces the reabsorption of sodium in renal tubules.

Prolutone has a blocking effect on the secretion of hypothalamic factors LH and FSH release, inhibits the formation of the pituitary gonadotropin-releasing hormone and inhibits ovulation.

Pharmacokinetics

After IM injection Prolutone is absorbed rapidly and almost completely. This medication metabolized in the liver, the majority of metabolites formed conjugates with glucuronic and sulfuric acids. T_1/2 from plasma is a few minutes. This medicine is excreted in the urine - 50-60%, in feces - more than 10%. The number of metabolites which are excreted in the urine varies, depending on the phase of the corpus luteum.

Why is Prolutone prescribed?

Capsules Oral - premenstrual syndrome, fibrocystic breast disease, premenopausal, menopause, including premature, postmenopausal women - as the progestogen component of hormone replacement therapy in combination with estrogen; Capsules Vaginal - HRT when dormant in the absence of ovarian Prolutone (egg donation), support the luteal phase in preparation for in vitro fertilization, support the luteal phase in spontaneous or induced menstrual cycle, prevention of habitual abortion by threatening and progestogen deficiency, endocrine infertility, prevention of uterine fibroids, endometriosis.

Solution in oil: amenorrhea, oligomenorrhea, algomenorrhea (on the basis of hypogenitalism), anovulatory metrorrhagia, infertility, endocrine (including failure of the corpus luteum), the threat of termination of pregnancy, diagnosis of estrogen.

Gel for external use: mammalgia, disease of the breast.

Dysfunctional uterine bleeding, metrorrhagia, amenorrhea, recurrent miscarriage.

Contraception.

Dosage and administration

Orally, intravaginally, IM, locally. The dosing regimen is individual. The dose, frequency and duration of treatment with Prolutone are determined according to the scheme depending on the indications and the clinical situation.

Prolutone side effects, adverse reactions

Cardiovascular system: increased blood pressure.

Metabolic: edema.

Digestive system: liver problems, jaundice, rarely - nausea, vomiting.

Endocrine: rare (with prolonged use) - decreased libido, weight gain, pain and tension in the breasts, irregular uterine bleeding.

CNS: rare (with prolonged use) - headache, depression.

Prolutone contraindications

Severe liver or kidney problems, hepatitis, thromboembolic disease, vaginal bleeding of not established genesis, breast carcinoma (except for cases in which Prolutone is used in a combination therapy of this disease).

Using during pregnancy and breastfeeding

In cases of extreme necessity Prolutone may be used during pregnancy in the established failure of the corpus luteum hormone.

Prolutone is not used in women planning a pregnancy in the near future.

Special instructions

Prolutone is used with caution in patients with cardiovascular disease, impaired liver or kidney problems, diabetes, asthma, epilepsy, migraine, depression.

Prolutone drug interactions

Prolutone reduces the intensity of the drugs that stimulate the smooth muscles of the uterus, anabolic steroids, gonadotropin-releasing hormone of the anterior pituitary.

This medication reduces the lactogenic effect of oxytocin.

Prolutone enhances the action of diuretics, antihypertensive drugs, immunosuppressive drugs. Simultaneous administration of Prolutone with barbiturates it is marked decrease of Prolutone effects.

Prolutone pharmaceutical active ingredients containing related brand and generic drugs:

Progesterone

Prolutone available forms, composition, doses:

Injectable; Injection; Progesterone 100 mg / ml

Prolutone destination | category:

Human:
Oestrogens and progesterones and related synthetic drugs
Progestins

Prolutone Anatomical Therapeutic Chemical codes:

G03DA04 - Progesterone

Prolutone pharmaceutical companies:

Bayer Schering Pharma

References

Dailymed."PROGESTERONE INJECTION, SOLUTION [ACTAVIS PHARMA, INC.]". https://dailymed.nlm.nih.gov/dailym... (accessed August 28, 2018).
Dailymed."PROGESTERONE: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailym... (accessed August 28, 2018).
"progesterone". https://pubchem.ncbi.nlm.nih.gov/co... (accessed August 28, 2018).

Frequently asked Questions

Can i drive or operate heavy machine after consuming Prolutone?

Depending on the reaction of the Prolutone after taken, if you are feeling dizziness, drowsiness or any weakness as a reaction on your body, Then consider Prolutone not safe to drive or operate heavy machine after consumption. Meaning that, do not drive or operate heavy duty machines after taking the capsule if the capsule has a strange reaction on your body like dizziness, drowsiness. As prescribed by a pharmacist, it is dangerous to take alcohol while taking medicines as it exposed patients to drowsiness and health risk. Please take note of such effect most especially when taking Primosa capsule. It's advisable to consult your doctor on time for a proper recommendation and medical consultations.

Is Prolutone addictive or habit forming?

Medicines are not designed with the mind of creating an addiction or abuse on the health of the users. Addictive Medicine is categorically called Controlled substances by the government. For instance, Schedule H or X in India and schedule II-V in the US are controlled substances.

Please consult the medicine instruction manual on how to use and ensure it is not a controlled substance.In conclusion, self medication is a killer to your health. Consult your doctor for a proper prescription, recommendation, and guidiance.

Review

sdrugs.com conducted a study on Prolutone, and the result of the survey is set out below. It is noteworthy that the product of the survey is based on the perception and impressions of the visitors of the website as well as the views of Prolutone consumers. We, as a result of this, advice that you do not base your therapeutic or medical decisions on this result, but rather consult your certified medical experts for their recommendations.