DRUGS & SUPPLEMENTS
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Piracem is a nootropic drugs. This medication has a positive effect on metabolism and blood circulation of the brain. It increases glucose utilization, improves the course of metabolic processes, improves microcirculation in the ischemic areas, and inhibits the aggregation of activated platelets. Piracem has a protective effect for brain damage caused by hypoxia, intoxication, an electric shock. This drug improves the integrative activity of the brain. Piracem does not have a sedative and stimulating effect.
Piracem after oral administration is quickly and almost completely absorbed from the gastrointestinal tract. Cmax in plasma is reached after about 30 minutes, in the cerebrospinal fluid in 2-8 hours. The apparent Vd is 0.6 L / kg. Piracem does not bind to plasma proteins.
This medication distributed in all organs and tissues, crosses the blood-brain barrier and placental barrier. Piracem selectively accumulates in the tissues of the cerebral cortex, predominantly in the frontal, parietal and occipital lobes, the cerebellum and basal ganglia.
T1/2 from plasma is 4-5 hours, from cerebrospinal fluid is 6-8 hours. This drug excreted by the kidneys unchanged. In renal insufficiency T1/2 is increases.
Memory disturbances, dizziness, decreased concentration, emotional lability, dementia due to cerebrovascular events, brain injury, Alzheimer's disease, in old age; comatose state of vascular, traumatic or toxic origin; treatment withdrawal and psychoorganic syndrome in chronic alcoholism; learning disorders in children not related to inadequate training or the peculiarities of family environment (as part of combination therapy); sickle cell anemia (as part of combination therapy).
Oral for adults 30-160 mg / kg in 2-4 doses. Duration of treatment is 6-8 weeks.
If necessary, Piracem use IM or IV at an initial dose of 10 g / day. At IV administration to patients in critical condition daily dose may reach 12 g. After clinical improvement the dose is gradually reduced and transferred to an oral administration.
For children the oral dose is 30-50 mg / kg in 2-3 doses. The treatment should be continued for at least 3 weeks.
Digestive system: rarely - dyspeptic symptoms, abdominal pain.
CNS: rarely - nervousness, agitation, irritability, anxiety, insomnia, dizziness, headache, tremor, in some cases - weakness, drowsiness.
Other: increased sexual activity.
Hemorrhagic stroke, severe renal impairment, hypersensitivity to Piracem.
Adequate and well-controlled studies safety of Piracem during pregnancy has not been carried out. Piracem use is possible only in cases where the intended benefits to the mother outweigh the risks to the fetus.
Piracem apparently passes into breast milk. If necessary use during lactation should solve the issue of termination of breastfeeding.
In experimental studies in animals it was showed no adverse effects of Piracem on the fetus.
Piracem use with careful in patients with severe hemostasis disorders, surgery for large and heavy bleeding; with renal insufficiency.
It is recommended constant monitoring of indicators of kidney function.
In the case of sleep disorders is recommended to cancel an evening reception of Piracem, attaching the dose to day reception.
Simultaneous administration of Piracem with:
Symptoms: amplification of possible side effects.
Treatment: gastric lavage, activated charcoal, symptomatic therapy, hemodialysis is possible (efficiency 50-60%); there is no specific antidote.
Depending on the reaction of the Piracem after taken, if you are feeling dizziness, drowsiness or any weakness as a reaction on your body, Then consider Piracem not safe to drive or operate heavy machine after consumption. Meaning that, do not drive or operate heavy duty machines after taking the capsule if the capsule has a strange reaction on your body like dizziness, drowsiness. As prescribed by a pharmacist, it is dangerous to take alcohol while taking medicines as it exposed patients to drowsiness and health risk. Please take note of such effect most especially when taking Primosa capsule. It's advisable to consult your doctor on time for a proper recommendation and medical consultations.Is Piracem addictive or habit forming?
Medicines are not designed with the mind of creating an addiction or abuse on the health of the users. Addictive Medicine is categorically called Controlled substances by the government. For instance, Schedule H or X in India and schedule II-V in the US are controlled substances.
Please consult the medicine instruction manual on how to use and ensure it is not a controlled substance.In conclusion, self medication is a killer to your health. Consult your doctor for a proper prescription, recommendation, and guidiance.
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The information was verified by Dr. Rachana Salvi, MD Pharmacology