DRUGS & SUPPLEMENTS
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Omeprazole is an inhibitor of H+ K+ ATPase. This medication inhibits the activity of H+-K+-ATPase in gastric parietal cells and thus blocks the final stage of hydrochloric acid secretion. This leads to a reduction in basal and stimulated secretion, regardless of the nature of the stimulus. Due to the reduction of acid secretion Omeprazole reduces or normalizes the effects of acid in the esophagus in patients with reflux esophagitis.
Omeprazole has a bactericidal effect on Helicobacter pylori. Eradication of H. pylori when Omeprazole used with antibiotics allows to quickly arrest the symptoms, to take a high degree of healing of damaged mucosa and persistent long-term remission and reduce the likelihood of bleeding from the gastrointestinal tract.
After oral administration Omeprazole is rapidly absorbed from the gastrointestinal tract. This drug penetrates the parietal cells of gastric mucosa. Plasma protein binding is about 95%. Omeprazole is biotransformed in the liver. Excreted by the kidneys - 72-80%, in the faeces - about 20%. T1/2 is 0.5-1 h. In patients with chronic liver diseases T1/2 increases up to 3 hours.
Gastric ulcer and duodenal ulcer in acute phase (including associated with Helicobacter pylori), reflux esophagitis, Zollinger-Ellison syndrome, erosive and ulcerative lesions of gastric and duodenal ulcers associated with taking NSAIDs.
The dosing regimen of Omeprazole is individual. When this medication is administered orally of the single dose is 20-40 mg. The daily dose is 20-80 mg, the frequency of use is 1-2 times / day. The duration of treatment is 2-8 weeks.
Digestive system: rarely - nausea, diarrhea, constipation, abdominal pain, flatulence.
CNS: rarely - headache, dizziness, weakness.
Hemopoietic system: in some cases - anemia, eosinopenia, neutropenia, thrombocytopenia.
Urinary system: in some cases - hematuria, proteinuria.
Musculoskeletal system: in some cases - arthralgia, muscle weakness, myalgia.
Allergic reactions: rarely - skin rash.
Chronic liver disease, hypersensitivity to Omeprazole.
In the absence of clinical experience with Omeprazole it is not recommended to use this drug during pregnancy. If necessary to use during Omeprazole lactation it should been solve the issue of termination of breastfeeding.
Category effects on the fetus by FDA - C.
Before the treatment with Omeprazole it is necessary to exclude the possibility of a malignant process because Omeprazole treatment can mask symptoms and delay the correct diagnosis.
Therapy with Omeprazole may affects results of laboratory studies of liver and gastrin concentrations in blood plasma.
Due to lack of experience in clinical application of Omeprazole this medicine is not recommended for children.
This medication alters the bioavailability of any drug, absorption depends on pH (ketoconazole, iron salts, etc.). Omeprazole slows down the elimination of drugs metabolized in the liver by microsomal oxidation (warfarin, diazepam, phenytoin, etc.).
Omeprazole enhances the action of coumarin and diphenine, does not change - NSAIDs. This drug increases (relative) the concentration of clarithromycin in the blood; may increases the leukopenic and thrombocytopenic effects of depressants hematopoiesis drugs. Substance for intravenous infusion is compatible only with saline and dextrose (using other solvents may decrease the stability of Omeprazole due to changes in pH of infusion medium).
Symptoms: dry mouth, nausea, blurred vision, headache, increased sweating, flushing, tachycardia, drowsiness, confusion.
Treatment: symptomatic, dialysis is ineffective.
|Apo-Omeprazole 20 mg Capsule/Sustained Release Tablet||1.15 USD|
|CVS Pharmacy omeprazole dr 20 mg tablet||0.53 USD|
|Capsules, Delayed Release; Oral; Omeprazole 10 mg|
|Capsules, Delayed Release; Oral; Omeprazole 20 mg|
|Capsules, Delayed Release; Oral; Omeprazole 40 mg|
|Capsules, Gastro-Resistant; Oral; Omeprazole 10 mg|
|Capsules, Gastro-Resistant; Oral; Omeprazole 20 mg|
|Capsules; Oral; Omeprazole 10 mg|
|Capsules; Oral; Omeprazole 20 mg|
|Capsules; Oral; Omeprazole 40 mg|
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|Losec (Sustained-Release Tablet) 20 mg Capsule/Sustained Release Tablet||2.48 USD|
|Mylan-Omeprazole 10 mg Capsule/Sustained Release Tablet||0.86 USD|
|Mylan-Omeprazole 20 mg Capsule/Sustained Release Tablet||1.15 USD|
|Omeprazole 10 mg Delayed Release Capsule||3.13 USD|
|Omeprazole 20 mg Delayed Release Capsule||4.32 USD|
|Omeprazole 28 20 mg Enteric Coated Tabs Box||25.99 USD|
|Omeprazole 40 mg Delayed Release Capsule||7.69 USD|
|Omeprazole dr 20 mg tablet||0.66 USD|
|Omeprazole powder||5.05 USD|
|Pms-Omeprazole (Delayed Release Tablet) 20 mg Capsule/Sustained Release Tablet||1.15 USD|
|Pms-Omeprazole (Sustained-Release Capsule) 20 mg Capsule/Sustained Release Tablet||1.15 USD|
|PriLOSEC 30 10 mg Delayed Release Capsule Bottle||174.37 USD|
|PriLOSEC 30 20 mg Delayed Release Capsule Bottle||459.99 USD|
|PriLOSEC 40 mg Delayed Release Capsule||9.59 USD|
|PriLOSEC OTC 14 20 mg Enteric Coated Tabs Box||19.99 USD|
|Prilosec 20 mg capsule dr||6.15 USD|
|Prilosec dr 10 mg capsule||5.59 USD|
|Prilosec dr 20 mg capsule||6.24 USD|
|Prilosec dr 40 mg capsule||9.22 USD|
|Prilosec otc 20 mg tablet||0.76 USD|
|Ratio-Omeprazole (Sustained-Release Tablet) 20 mg Capsule/Sustained Release Tablet||1.15 USD|
|Sandoz Omeprazole (Sustained-Release Capsule) 10 mg Capsule/Sustained Release Tablet||0.86 USD|
|Sandoz Omeprazole (Sustained-Release Capsule) 20 mg Capsule/Sustained Release Tablet||1.15 USD|
|Tablets, Delayed Release; Oral; Omeprazole 20 mg|
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|Zegerid 40-1100 mg capsule||7.48 USD|
|Zegerid otc 20-1100 mg capsule||0.78 USD|
Depending on the reaction of the Omeprazole after taken, if you are feeling dizziness, drowsiness or any weakness as a reaction on your body, Then consider Omeprazole not safe to drive or operate heavy machine after consumption. Meaning that, do not drive or operate heavy duty machines after taking the capsule if the capsule has a strange reaction on your body like dizziness, drowsiness. As prescribed by a pharmacist, it is dangerous to take alcohol while taking medicines as it exposed patients to drowsiness and health risk. Please take note of such effect most especially when taking Primosa capsule. It's advisable to consult your doctor on time for a proper recommendation and medical consultations.Is Omeprazole addictive or habit forming?
Medicines are not designed with the mind of creating an addiction or abuse on the health of the users. Addictive Medicine is categorically called Controlled substances by the government. For instance, Schedule H or X in India and schedule II-V in the US are controlled substances.
Please consult the medicine instruction manual on how to use and ensure it is not a controlled substance.In conclusion, self medication is a killer to your health. Consult your doctor for a proper prescription, recommendation, and guidiance.
|It has side effects||1||100.0%|
|Once in a day||1||50.0%|
|Twice in a day||1||50.0%|
|With a meal||1||33.3%|
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The information was verified by Dr. Rachana Salvi, MD Pharmacology