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DRUGS & SUPPLEMENTS
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Olorest-F
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Olorest-F uses
Olorest-F consists of Fluoxetine, Olanzapine.Fluoxetine:
Pharmacological action
Olorest-F is an antidepressant, propylamine derivative. The mechanism of action is associated with selective blockade of the inverse of neuronal serotonin reuptake in the CNS. Olorest-F (Fluoxetine) is a weak antagonist of choline, adrenergic and histamine receptors. Unlike most antidepressants Olorest-F (Fluoxetine) apparently does not cause reduction of functional activity of postsynaptic beta-adrenergic receptors. This medication improves mood, reduces anxiety and stress, eliminates dysphoria. Olorest-F (Fluoxetine) does not cause sedation. When you receive a medium therapeutic doses of this drug it does not affect the function of cardiovascular and other systems.
Pharmacokinetics
Olorest-F (Fluoxetine) absorbed from the gastrointestinal tract. This medication is poorly metabolized in the "first pass" through the liver. The ingestion did not affect the extent of absorption, although it may slow its speed. Cmax in plasma is reached after 6-8 hours. Css in plasma is reached only after a continuous reception in a few weeks. The protein binding is 94.5%. Olorest-F (Fluoxetine) easily penetrates through the BBB.
Olorest-F (Fluoxetine) metabolized in the liver by demethylation to form the main active metabolite norfluoxetine.
T1/2 of Olorest-F (Fluoxetine) is 2-3 days, norfluoxetine - 7-9 days.
Why is Olorest-F prescribed?
Depressions of various origins, obsessive-compulsive disorders, bulimic neurosis.
Dosage and administration
The initial dose of Olorest-F is 20 mg 1 time / day in the morning, if necessary, the dose may be increased in 3-4 weeks. The frequency of reception is 2-3 times / day.
The maximum oral daily dose for adults is 80 mg.
Olorest-F (Fluoxetine) side effects, adverse reactions
CNS: anxiety, tremors, nervousness, drowsiness, headache, sleep disturbances.
Digestive system: diarrhea, nausea.
Metabolism: increased sweating, hypoglycemia, hyponatremia (especially in elderly patients and when hypovolemia).
Reproductive system: decreased libido.
Allergic reactions: skin rash, itching.
Other: pain in joints and muscles, shortness of breath, increased body temperature.
Olorest-F contraindications
Glaucoma, bladder atony, severe renal dysfunction, benign prostatic hyperplasia, co-administration of MAO inhibitors, convulsions of various origins, epilepsy, pregnancy, lactation, hypersensitivity to Olorest-F (Fluoxetine).
Using during pregnancy and breastfeeding
Olorest-F is contraindicated during pregnancy and lactation.
Special instructions
Olorest-F (Fluoxetine) should be used with caution in patients with impaired liver and kidney, with a history of epileptic seizures, cardio-vascular diseases.
Patients with diabetes may change in blood glucose levels that require correction dosing regimen of hypoglycemic drugs. When applied in debilitated patients with Olorest-F (Fluoxetine) increases the risk of epileptic seizures.
With the simultaneous application of Olorest-F (Fluoxetine) and electroconvulsive therapy may develop prolonged seizures.
Olorest-F (Fluoxetine) can be applied not earlier than 14 days after discontinuation of MAO inhibitors. The period after the abolition of Olorest-F (Fluoxetine) before therapy MAO inhibitors should not be less than 5 weeks.
Elderly patients need correction of dosing regimen.
Safety of Olorest-F (Fluoxetine) in children has not been established.
During the period of treatment it needed to avoid use alcohol.
During the period of treatment should refrain from potentially hazardous activities requiring increased attention and rapid psychomotor reactions.
Olorest-F drug interactions
Simultaneous administration of Olorest-F (Fluoxetine) with:
Olorest-F in case of emergency / overdose
Symptoms: nausea, vomiting, agitation, restlessness, hypomania, seizures, large seizures. There were describes two deaths from acute overdose of Olorest-F (Fluoxetine) (in combination with maprotiline, codeine, temazepam).
Treatment: gastric lavage, taking activated charcoal, sorbitol, ECG monitoring, symptomatic and supportive therapy, when convulsions - diazepam. There is no specific antidote. Forced diuresis, peritoneal dialysis, hemodialysis, blood transfusions are ineffective.
Olanzapine:
Olorest-F information
This medication is a well-known drug used for the corrective treatment of neuro-psychiatric disorders like schizophrenia. Olorest-F (Olanzapine) is also used for correcting mental disorders like acute mania or bipolar disorder, to be specific. This drug can also be coupled up with both divalproex and lithium, for combination therapy. Olorest-F (Olanzapine) is a nascent member of the anti-psychotic group of drugs that affects the human psyche. Already an established choice of physicians and sufferers, Olorest-F (Olanzapine) balances the chemicals naturally found in human brain to stabilize the agonizing symptoms of a schizophrenic. The popularity of this drug has increased in the recent times due to its better and faster actions in controlling and lessening symptoms like delusions, apathy, hallucinations, social alienation over traditional anti-psychotics drugs. Olorest-F (Olanzapine), is however, effective in treating other disorders as well.
Olorest-F warnings
It is always advisable to consult your physician before taking the drug. Special care needs to be taken if you have problems pertaining to the liver or heart. Also ask your doctor whether it will be judicious or not to take this drug if you have chronic diseases like epilepsy, diabetes, enlarged prostrate, glaucoma or phenylketonuria syndromes. Listed in category C of FDA pregnancy, it is difficult to say for sure whether this drug is safe during pregnancy or not. So it is always better to consult a physician if anyone wants to use this drug during pre natal or breast-feeding stage.
Because of its nerve soothing factors, Olorest-F (Olanzapine) sometimes may cause dizziness and hamper judgment, thinking, and motor skills. It can also interfere with body temperature regulation. So it is better to be very careful while driving. New users of Olorest-F (Olanzapine) may experience a condition called Neuroleptic Malignant Syndrome. The normally found symptoms of this condition are high fever, muscle rigidity, irregular pulse or blood pressure, rapid heartbeat, excessive perspiration, and changes in heart rhythm. Don't delay to see a doctor if any of these symptoms appear. Use of Olorest-F (Olanzapine) in case of elderly women involves a risk of developing Tardive dyskinesia. This condition involves slow, rhythmical, involuntary movements. This problem, though more found in women, also surfaces in older adults. The use of this drug should be immediately stopped if any such symptom appears. Olorest-F (Olanzapine) is also not advisable for children having phenylketonuria syndrome.
Olorest-F (Olanzapine) may not work in harmony if you are already using any of the following drugs:
Carbamazepine (Tegretol)
Fluvoxamine (Luvox)
Levodopa (Sinemet, Larodopa, Atamet, Stalevo)
Selegiline (Eldepryl)
Pramipexole (Mirapex)
Ropinirole (Requip)
Olorest-F side effects
The most prominent side effects of the drug Olorest-F (Olanzapine) include dizziness, drowsiness, dry mouth, fatigue, constipation, upset stomach, increased appetite, or mild trembling, weight gain etc. Consulting a physician is the best way out in such cases as there are tested alternatives to correct such side effects.
Olorest-F (Olanzapine) can also give birth to serious side effects like severe abdominal pain, abnormal gait, irritation, anxiety, back pain, behavior problems, blood in urine, blurred vision, chest pain, cough, dehydration, fluctuating blood pressure, eye problems, feeling of well-being, fever, headache, hostility, indigestion, inflammation of the nasal passages and throat, insomnia, joint pain, movement disorders, muscle rigidity, nausea, nervousness, pain in arms and legs, rapid heartbeat, restlessness, abnormal dreams. Cases with decreased sex drive, dental pain, breathing trouble, emotional instability, involuntary movement, joint stiffness, menstrual irregularities, sleepiness, suicide attempts, sweating, swelling of arms and legs, thirst, twitching, urinary problems, vaginal infection, vomiting after usage of Olorest-F (Olanzapine) are also abundant.
Cases with side effects like black bowel movements, stomach upset, abnormal ejaculation, bleeding, blood clots, breast pain, bone pain, breast growth in males, burping, chills, congestive heart failure, difficulty swallowing, dry eyes, dry skin, ear pain, change in taste sensation, enlarged abdomen, fever, hair loss, hangover feeling, heart attack, inability to control bowel movements, migraine, mouth sores, neck pain, neck rigidity, osteoporosis, pallor, rash, rectal bleeding, rheumatoid arthritis, ringing in the ears, sensitivity to light, stroke, sudden death, swelling of face, swollen gums, yeast infection are rare but cannot be ruled out. It is advisable to see a doctor if any such symptom appears.
Olorest-F overdose
There is no denying the fact that Olorest-F (Olanzapine) is a wonder drug. But to be on the safer side it is always better to consult a physician and be sure about what is the right dose for you. So far no serious cases of Olorest-F (Olanzapine) overdose has been found. Overdose of the drug may not be detrimental to your existence but it can always cause fatal disorders. The symptoms of overdose generally include drowsiness and haltered speech. As soon as you feel that an overdose has been taken by mistake rush to a doctor for the corrective measures.
On the other hand, a missed dose of Olorest-F (Olanzapine) does not cause harmful damages. But as soon as you notice that a dose is missed take the missed dose. But if it is almost time for the next regularly scheduled dose, just skip the earlier dose and take the scheduled one. Remember, a wonder drug can cause fatal effects if taken without care.
Olorest-F usage guidelines
Always follow the doctor's prescription for the right usage guideline. Normally Olorest-F (Olanzapine) tablets should be taken in with a full glass of water. Usually taken once a day, Olorest-F (Olanzapine) can be taken with or without food. Olorest-F (Olanzapine) is also available in an injectable form. For the right dose always consult your physician. Don't stop using this drug without consulting your physician.
If the doctor suggests certain regular diagnostic check up or blood tests for evaluating the progress and side effects of the drug, don't ignore doing that. Also to get the best results don't forget to store Olorest-F (Olanzapine) at room temperature and keep away from moisture and heat.
Olorest-F pharmaceutical active ingredients containing related brand and generic drugs:
Olorest-F available forms, composition, doses:
Composition is the list of ingredients which combinedly form a medicine. Both active ingredients and inactive ingredients form the composition. The active ingredient gives the desired therapeutic effect whereas the inactive ingredient helps in making the medicine stable.
Doses are various strengths of the medicine like 10mg, 20mg, 30mg and so on. Each medicine comes in various doses which is decided by the manufacturer, that is, pharmaceutical company. The dose is decided on the severity of the symptom or disease.