DRUGS & SUPPLEMENTS

Nystatin

Name: Nystatin drug & pharmaceuticals. Nystatin available forms, doses, prices
Creator: sdrugs.com
Published: 2021-11-11T10:10:10+00:00

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Nystatin uses

Description
Clinical pharmacology
Indications and usage
Contraindications
Precautions
Adverse reactions
Overdosage
Dosage and administration
How supplied
Nystatin reviews

DESCRIPTION

Nystatin, USP is an antimycotic polyene antibiotic obtained from Streptomyces noursei. Its structural formula:

C₄₇H₇₅NO₁₇ M.W. 926.13

Nystatin Tablets USP contain the inactive ingredients: Corn Starch, Povidone, Compressible Sugar, Microcrystalline Cellulose, Sodium Starch Glycolate, Talc, Magnesium Stearate, Purified Water, and Coloring.

Structural formula for Nystatin

CLINICAL PHARMACOLOGY

Pharmacokinetics

Gastrointestinal absorption of Nystatin is insignificant. Most orally administered Nystatin is passed unchanged in the stool. In patients with renal insufficiency receiving oral therapy with conventional dosage forms, significant plasma concentrations of Nystatin may occasionally occur.

Microbiology

Nystatin is both fungistatic and fungicidal in vitro against a wide variety of yeasts and yeast like fungi. Candida albicans demonstrates no significant resistance to Nystatin in vitro on repeated subculture in increasing levels of Nystatin; other Candida species become quite resistant. Generally, resistance does not develop in vivo. Nystatin acts by binding to sterols in the cell membrane of susceptible Candida species with a resultant change in membrane permeability allowing leakage of intracellular components. Nystatin exhibits no appreciable activity against bacteria, protozoa, or viruses.

INDICATIONS AND USAGE

Nystatin tablets are intended for the treatment of non-esophageal mucus membrane gastrointestinal candidiasis.

CONTRAINDICATIONS

Nystatin tablets are contraindicated in patients with a history of hypersensitivity to any of their components.

PRECAUTIONS

General

This medication is not to be used for the treatment of systemic mycoses. Discontinue treatment if sensitization or irritation is reported during use.

Carcinogenesis, Mutagenesis, Impairment of Fertility

No long-term animal studies have been performed to evaluate carcinogenic potential. There also have been no studies to determine mutagenicity or whether this medication affects fertility in males or females.

Pregnancy

Teratogenic Effects

Pregnancy Category C

Animal reproduction studies have not been conducted with Nystatin. It is also not known whether Nystatin can cause fetal harm when administered to a pregnant woman or can affect reproduction capacity. Nystatin should be given to a pregnant woman only if clearly needed.

Nursing Mothers

It is not known whether Nystatin is excreted in human milk. Because many drugs are excreted in human milk, caution should be exercised when Nystatin is administered to a nursing woman.

ADVERSE REACTIONS

Nystatin is well tolerated even with prolonged therapy. Oral irritation and sensitization have been reported .

Gastrointestinal

Diarrhea (including one case of bloody diarrhea), nausea, vomiting, gastrointestinal upset/disturbances.

Dermatologic

Rash, including urticaria has been reported rarely. Stevens-Johnson syndrome has been reported very rarely.

Other

Tachycardia, bronchospasm, facial swelling, and nonspecific myalgia have also been rarely reported.

OVERDOSAGE

Oral doses of Nystatin in excess of five million units daily have caused nausea and gastrointestinal upset. There have been no reports of serious toxic effects of superinfections (see CLINICAL PHARMACOLOGY, Pharmacokinetics).

DOSAGE AND ADMINISTRATION

The usual therapeutic dosage is one to two tablets (500,000 to 1,000,000 units Nystatin) three times daily. Treatment should generally be continued for at least 48 hours after clinical cure to prevent relapse.

HOW SUPPLIED

Nystatin Tablets USP, 500,000 Units are round, convex, brown, film-coated tablet debossed with 93 on one side and 983 on the reverse and are packaged in bottles of 100 tablets (NDC 0093-0983-01).

Store at 20° to 25°C (68° to 77°F).

Dispense in a tight, light-resistant container as defined in the USP, with a child-resistant closure (as required).

Keep tightly closed.

KEEP THIS AND ALL MEDICATIONS OUT OF THE REACH OF CHILDREN.

Manufactured By:

TEVA CANADA LIMITED

Toronto, Canada M1B 2K9

Manufactured For:

TEVA PHARMACEUTICALS USA, INC.

North Wales, PA 19454

Rev. N 2/2016

NDC 0093-0983-01

Nystatin

Tablets USP

500,000 units (oral)

Rx only

100 TABLETS

TEVA

Nystatin pharmaceutical active ingredients containing related brand and generic drugs:

Nystatin

Nystatin available forms, composition, doses:

	Price
Capsules; Oral; Nystatin 500,000 units
Cream; Topical; Nystatin 100,000 units / g
Gel; Topical; Nystatin 200,000 IU / g
Mycostatin 100000 unit/gm Powder 15 gm Bottle	36.99 USD
Mycostatin 500000 unit orl tablet	0.48 USD
Nystat-rx 5 billion unit powder	447.0 USD
Nystatin 1 billion unit powder	452.08 USD
Nystatin 10 billion unit powder	3014.1 USD
Nystatin 100000 unit tablet	5.29 USD
Nystatin 100000 unit/gm Cream 15 gm Tube	6.5 USD
Nystatin 100000 unit/gm Ointment 15 gm Tube	12.99 USD
Nystatin 100000 unit/gm cream	0.1 USD
Nystatin 100000 unit/ml Suspension	0.25 USD
Nystatin 150 million unit powder	42.25 USD
Nystatin 150000000 unit powder	42.0 USD
Nystatin 150mu Bottle	94.5 USD
Nystatin 2 billion unit powder	1116.9 USD
Nystatin 5 billion unit powder	2096.1 USD
Nystatin 50 million unit powder	19.75 USD
Nystatin 500 million unit powder	130.75 USD
Nystatin 500000 unit oral tablet	0.68 USD
Nystatin 500000 unit tablet	0.71 USD
Nystatin Nystatin Powder 50 Million unit Bottle	39.99 USD
Nystatin vaginal tablet	5.0 USD
Nystop 100000 unit/gm Powder 15 gm Bottle	29.99 USD
Nystop 100000 unit/gm powder	1.6 USD
Ointment; Topical; Nystatin 100,000 IU / g
Ointment; Topical; Nystatin 100,000 units / g
Pedi-Dri 100000 unit/gm Powder 56.7 gm Bottle	105.87 USD
Pedi-dri topical powder	1.82 USD
Pms-Nystatin 100000 unit/ml Suspension	0.05 USD
Powder; Oral; Nystatin 100%
Powder; Topical; Nystatin 100,000 units / g
Ratio-Nystatin 100000 unit/ml Suspension	0.05 USD
Ratio-Nystatin 500000 unit Tablet	0.25 USD
Suppositories; Rectal; Nystatin 250,000 IU
Suppositories; Rectal; Nystatin 500,000 IU
Suppositories; Vaginal; Nystatin 250,000 IU
Suppositories; Vaginal; Nystatin 500,000 IU
Suspension; Oral; Nystatin 100,000 units / ml
Tablets, Film-Coated; Oral; Nystatin 250,000 IU
Tablets, Film-Coated; Oral; Nystatin 500,000 IU
Tablets; Oral; Nystatin 500,000 units
Tablets; Oral; Vaginal; Nystatin 100,000 units
Tablets; Vaginal; Nystatin 100,000 units

Nystatin destination | category:

Human:
Antifungals
Polyenes
Preparations for vaginal conditions

Nystatin Anatomical Therapeutic Chemical codes:

A07AA02 - Nystatin
D01AA01 - Nystatin
G01AA01 - Nystatin
G01AA51 - Nystatin, combinations

Nystatin pharmaceutical companies:

References

Dailymed."NYSTATIN TABLET, FILM COATED [TEVA PHARMACEUTICALS USA INC]". https://dailymed.nlm.nih.gov/dailym... (accessed August 28, 2018).

Frequently asked Questions

Can i drive or operate heavy machine after consuming Nystatin?

Depending on the reaction of the Nystatin after taken, if you are feeling dizziness, drowsiness or any weakness as a reaction on your body, Then consider Nystatin not safe to drive or operate heavy machine after consumption. Meaning that, do not drive or operate heavy duty machines after taking the capsule if the capsule has a strange reaction on your body like dizziness, drowsiness. As prescribed by a pharmacist, it is dangerous to take alcohol while taking medicines as it exposed patients to drowsiness and health risk. Please take note of such effect most especially when taking Primosa capsule. It's advisable to consult your doctor on time for a proper recommendation and medical consultations.

Is Nystatin addictive or habit forming?

Medicines are not designed with the mind of creating an addiction or abuse on the health of the users. Addictive Medicine is categorically called Controlled substances by the government. For instance, Schedule H or X in India and schedule II-V in the US are controlled substances.

Please consult the medicine instruction manual on how to use and ensure it is not a controlled substance.In conclusion, self medication is a killer to your health. Consult your doctor for a proper prescription, recommendation, and guidiance.

Review

sdrugs.com conducted a study on Nystatin, and the result of the survey is set out below. It is noteworthy that the product of the survey is based on the perception and impressions of the visitors of the website as well as the views of Nystatin consumers. We, as a result of this, advice that you do not base your therapeutic or medical decisions on this result, but rather consult your certified medical experts for their recommendations.