DRUGS & SUPPLEMENTS
How old is patient?
Nedoxal is an analgesic-antipyretic. It has analgesic, antipyretic and weak anti-inflammatory action. The mechanism of action is associated with inhibition of prostaglandin synthesis, the predominant influence on the thermoregulation center in the hypothalamus, enhances heat transfer.
Pain weak and moderate intensity of different genesis (including headache, migraine, toothache, neuralgia, myalgia, algomenorrhea; pain in trauma, burns). Fever in infectious and inflammatory diseases.
Oral or rectally adults and adolescents with a body weight over 60 kg is used in a single dose of 500 mg, the multiplicity of admission - up to 4 times / Maximum duration of treatment - 5-7 days.
Maximum dose: single - 1 g, daily - 4 g.
Single dose for oral administration for children aged 6-12 years - 250-500 mg, 1-5 years - 120-250 mg, from 3 months to 1 year - 60-120 mg, up to 3 months - 10 mg / kg. Single dose rectal in children aged 6-12 years - 250-500 mg, 1-5 years - 125-250 mg.
Multiplicity - 4 at intervals of not less than 4 h. The maximum duration of treatment - 3 days.
Maximum dose: 4 single dose per day.
Digestive system: rarely - dyspepsia; long-term use at high doses - hepatotoxic effects, methemoglobinemia, renal dysfunction and liver, hypochromic anemia. Hemopoietic system: rarely - thrombocytopenia, leukopenia, pancytopenia, neutropenia, agranulocytosis. Allergic reactions: rarely - skin rash, itching, hives.
Chronic active alcoholism, increased sensitivity to Nedoxal, marked disturbances of liver function and / or kidney disease, anemia, pregnancy (I term).
Nedoxal (Acetaminophen) crosses the placental barrier. So far, no observed adverse effects of Nedoxal (Acetaminophen) on the fetus in humans.
Nedoxal (Acetaminophen) is excreted in breast milk: the content in milk was 0.04-0.23% of the dose adopted mother.
If necessary, use of Nedoxal (Acetaminophen) during pregnancy and lactation (breastfeeding) should carefully weigh the potential benefits of therapy for the mother and the potential risk to the fetus or child.
In experimental studies found no embryotoxic, teratogenic and mutagenic action of Nedoxal (Acetaminophen).
Nedoxal is used with caution in patients with disorders of the liver and kidneys, with benign hyperbilirubinemia, as well as in elderly patients.
With prolonged use of Nedoxal (Acetaminophen) is necessary to monitor patterns of peripheral blood and functional state of the liver.
Used for treatment of premenstrual tension syndrome in combination with pamabrom (diuretic, a derivative of xanthine) and mepyramine (Histamine H1-receptors blocker).
With the simultaneous use with inducers of microsomal liver enzymes, means having hepatotoxic effect, increasing the risk of hepatotoxic action of Nedoxal (Acetaminophen).
With the simultaneous use of anticoagulants may be slight to moderate increase in prothrombin time.
With the simultaneous use of anticholinergics may decrease absorption of Nedoxal (Acetaminophen).
With the simultaneous use of oral contraceptives accelerated excretion of Nedoxal (Acetaminophen) from the body and may reduce its analgesic action.
With the simultaneous use with urological means reduced their effectiveness.
With the simultaneous use of activated charcoal reduced bioavailability of Nedoxal (Acetaminophen).
When Nedoxal (Acetaminophen) applied simultaneously with diazepam may decrease excretion of diazepam.
There have been reports about the possibility of enhancing mielodepression effect of zidovudine while applying with Nedoxal (Acetaminophen). A case of severe toxic liver injury.
Described cases of toxic effects of Nedoxal (Acetaminophen), while the use of isoniazid.
When applied simultaneously with carbamazepine, phenytoin, phenobarbital, primidonom decreases the effectiveness of Nedoxal (Acetaminophen), which is caused by an increase in its metabolism and excretion from the body. Cases of hepatotoxicity, while the use of Nedoxal (Acetaminophen) and phenobarbital.
In applying cholestyramine a period of less than 1 h after administration of Nedoxal (Acetaminophen) may decrease of its absorption.
At simultaneous application with lamotrigine moderately increased excretion of lamotrigine from the body.
With the simultaneous use of metoclopramide may increase absorption of Nedoxal (Acetaminophen) and its increased concentration in blood plasma.
When applied simultaneously with probenecid may decrease clearance of Nedoxal (Acetaminophen), with rifampicin, sulfinpyrazone - may increase clearance of Nedoxal (Acetaminophen) due to increasing its metabolism in the liver.
At simultaneous application of Nedoxal (Acetaminophen) with ethinylestradiol increases absorption of Nedoxal (Acetaminophen) from the gut.
Enhances the effect of indirect anticoagulants (coumarin derivatives and indandione). Antipyretic and analgesic activity of caffeine increases, reduce - rifampicin, phenobarbital and alcohol (accelerated biotransformation, inducing microsomal liver enzymes).
At a reception in toxic doses (10-15 g in adults) may develop liver necrosis.
Symptoms of overdose may include: nausea, vomiting, loss of appetite, sweating, extreme tiredness, unusual bleeding or bruising, pain in the upper right part of the stomach, yellowing of the skin or eyes, flu-like symptoms
Nedoxal (Naproxen Sodium) is an anti-inflammatory non-steroidal anti-inflammatory (NSAID) medicine. Nedoxal (Naproxen Sodium) Actavis's actions help reduce the chemicals found in the patient's organism that are usually responsible for the triggering of inflammation and pain.
Nedoxal (Naproxen Sodium) is a drug normally prescribed in the treatment of pain, stiffness or inflammation that are usually triggered by medical disorders such as Gout, Osteoarthritis, menstruation abdominal cramps, rheumatoid arthritis, ankylosing spondylitis, injury, buritis and tendonitis.
Nedoxal (Naproxen Sodium) could also be prescribed in the treatment of other medical conditions that have not been mentioned here.
While the patient is following a treatment with Nedoxal (Naproxen Sodium) Actavis, he or she should avoid consuming big amounts of alcohol. It is recommended that alcohol drinks should be entirely avoided as they increase the danger of stomach bleeding. Therefore, if the patient is consuming more than 3 bottles of different alcoholic beverages he or she might not be allowed to start a treatment with Nedoxal (Naproxen Sodium) Actavis.
Nedoxal (Naproxen Sodium) can lead to drowsiness and dizziness. If you are following a treatment with this drug you should be careful while performing actions that require mental and physical alertness. The treatment with Nedoxal (Naproxen Sodium) should be carefully monitored in the case of patients suffering from any of the next medical disorders:
Allergic reactions to Aspirin (or any other NSAIDs)
High blood pressure
Congestive heart disease
If you are suffering from any of these medical disorders you might not be allowed to start a treatment with Nedoxal (Naproxen Sodium) Actavis.
Nedoxal (Naproxen Sodium) is a Category B FDA pregnancy drug. Therefore it is not considered to be harmful to an unborn child. However, if you are pregnant, consult with your doctor before starting a treatment with Nedoxal (Naproxen Sodium) Actavis. Nedoxal (Naproxen Sodium) (one of Nedoxal (Naproxen Sodium) Actavis's main ingredients) can pass into breast milk. If you are nursing an infant you should consult with your doctor before starting a treatment with Nedoxal (Naproxen Sodium) Actavis.
Nedoxal (Naproxen Sodium) ought to be taken in just like your doctor told you to. Do not disobey the physician's instructions.
You should accompany each dose of the drug with a glass of water (from 6 to 8 ounces of liquid). Do not take Nedoxal (Naproxen Sodium) on an empty stomach as it can cause stomach upset. Do not stop your treatment with this drug without your doctor's consent even if you do not feel better after a few days of treatment.
Ask your doctor to calculate the dose of Nedoxal (Naproxen Sodium) that suits you best. The correct dosage varies from one person to another, as it depends on a couple of factors.
Reported Nedoxal (Naproxen Sodium) overdose symptoms are:
Tingling sensation in legs and arms
No or little urine production
Shallow and slow breathing
Ringing in the ears
If you are experiencing any of the symptoms listed here, you are in need of medical attention (inform your doctor immediately).
Nedoxal (Naproxen Sodium) can be taken in when you need it or on a regular basis. If you are following a treatment with Nedoxal (Naproxen Sodium) Actavis, try not to miss any of your doses. If you happen to miss one take it as soon as possible. If it is almost time for another dose, skip the one that you have missed and continue with your regular schedule. You should not take in a double dose of this drug.
Very serious side effects of Nedoxal (Naproxen Sodium) are bloody vomit or bloody stools.
Other dangerous side effects of Nedoxal (Naproxen Sodium) are:
Allergic reactions (difficulty while breathing, throat closing, hives, swelling of mouth, lips and tongue).
Ringing in the ears
Stomach cramps or stomach upsets, indigestion or heartburn
Other side effects of the drug are:
There are other mild side effects that can also occur if you are taking Nedoxal (Naproxen Sodium) Actavis. Inform your physician if you feel anything disturbing or unusual.
You should inform your doctor if you are following a treatment with any of the drugs listed here:
Cold and cough medicines
Steroids (like prednisone)
If you are taking any of these drugs you may not be allowed to start taking Nedoxal (Naproxen Sodium) Actavis. Ask for your doctor's advice before you start a treatment with this drug.
Depending on the reaction of the Nedoxal after taken, if you are feeling dizziness, drowsiness or any weakness as a reaction on your body, Then consider Nedoxal not safe to drive or operate heavy machine after consumption. Meaning that, do not drive or operate heavy duty machines after taking the capsule if the capsule has a strange reaction on your body like dizziness, drowsiness. As prescribed by a pharmacist, it is dangerous to take alcohol while taking medicines as it exposed patients to drowsiness and health risk. Please take note of such effect most especially when taking Primosa capsule. It's advisable to consult your doctor on time for a proper recommendation and medical consultations.Is Nedoxal addictive or habit forming?
Medicines are not designed with the mind of creating an addiction or abuse on the health of the users. Addictive Medicine is categorically called Controlled substances by the government. For instance, Schedule H or X in India and schedule II-V in the US are controlled substances.
Please consult the medicine instruction manual on how to use and ensure it is not a controlled substance.In conclusion, self medication is a killer to your health. Consult your doctor for a proper prescription, recommendation, and guidiance.
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The information was verified by Dr. Rachana Salvi, MD Pharmacology