DRUGS & SUPPLEMENTS
Nariz is a calcium channel blocker class IV with a predominant effect on the brain vessels, a derivative of piperazine. This medication improves cerebral, coronary and peripheral circulation. Nariz violates the entrance of calcium ions into vascular smooth muscle cells. This drug lowers the tone of arteriolar smooth muscle, decreases the vasoconstrictor response to biogenic substances. Nariz reduces the excitability of the vestibular apparatus. In patients with impaired peripheral circulation Nariz improves blood flow and potentiates postischemic hyperemia. This medicine increases the resistance of tissue to hypoxia.
After oral administration Nariz is absorbed from the gastrointestinal tract, Cmax in plasma is reached after 1-4 h. The plasma protein binding is 91%. This medication is metabolized. T1/2 is 3-6 hours. Nariz is eliminated through the intestine largely unchanged, with the urine - mainly in the form of metabolites.
Why is Nariz prescribed?
Ischemic attacks. Labyrinth disorders (including for maintenance therapy for dizziness, tinnitus, nystagmus, nausea and vomiting of labyrinth origin). Motion sickness (as a prophylactic agent). Prophylaxis of migraine. Meniere's disease. Prevention and treatment of disorders of peripheral circulation - atherosclerosis, thromboangiitis obliterans, Raynaud's disease, diabetic angiopathy, acrocyanosis.
Dosage and administration
The dosage regimen is individual. Nariz is taken orally in 25-50-75 mg 3 times / day after a meal. If necessary, the treatment can begin with half the dose and gradually increasing. To achieve the optimal therapeutic effect is used continuously for several months.
Nariz side effects, adverse reactions
Digestive system: dyspepsia, dry mouth, rarely - cholestatic jaundice.
CNS: headache, drowsiness; in elderly patients in long-term use may be extrapyramidal symptoms, depression.
Allergic reactions: rarely - skin rash.
Other: weight gain, increased sweating, in rare cases - lupus-like syndrome, lichen planus.
Hypersensitivity to Nariz.
Using during pregnancy and breastfeeding
During pregnancy and lactation Nariz usage is possible only in exceptional cases, when the expected benefit to the mother far outweighs the potential risk to the fetus or infant.
Use Nariz with caution in patients with hypertension.
With prolonged use is recommended to perform control examination of liver, kidney, peripheral blood picture.
At the beginning of treatment you should refrain from potentially hazardous activities that require attention and speed of psychomotor reactions.
Nariz drug interactions
When this drug applied simultaneously with:
- tricyclic antidepressants, hypnotics, drugs that have a sedative effect, alcohol, ethanol-containing medication increases the effects on the CNS.
- antihypertensive drugs increased hypotensive effect.
- nootropics, vasodilators - increases the action of nootropic drugs and vasodilators.
- phenylpropanolamine reduces sedation effect of Nariz Quality Pharmaceutical Laboratory.
Nariz in case of emergency / overdose
Treatment: gastric lavage, taking activated charcoal, symptomatic therapy. There is no a specific antidote.
Nariz pharmaceutical active ingredients containing related brand and generic drugs:
Active ingredient is the part of the drug or medicine which is biologically active. This portion of the drug is responsible for the main action of the drug which is intended to cure or reduce the symptom or disease. The other portions of the drug which are inactive are called excipients; there role is to act as vehicle or binder. In contrast to active ingredient, the inactive ingredient's role is not significant in the cure or treatment of the disease. There can be one or more active ingredients in a drug.
Nariz available forms, composition, doses:
Form of the medicine is the form in which the medicine is marketed in the market, for example, a medicine X can be in the form of capsule or the form of chewable tablet or the form of tablet. Sometimes same medicine can be available as injection form. Each medicine cannot be in all forms but can be marketed in 1, 2, or 3 forms which the pharmaceutical company decided based on various background research results.
Composition is the list of ingredients which combinedly form a medicine. Both active ingredients and inactive ingredients form the composition. The active ingredient gives the desired therapeutic effect whereas the inactive ingredient helps in making the medicine stable.
Doses are various strengths of the medicine like 10mg, 20mg, 30mg and so on. Each medicine comes in various doses which is decided by the manufacturer, that is, pharmaceutical company. The dose is decided on the severity of the symptom or disease.
Nariz destination | category:
Destination is defined as the organism to which the drug or medicine is targeted. For most of the drugs what we discuss, human is the drug destination.
Drug category can be defined as major classification of the drug. For example, an antihistaminic or an antipyretic or anti anginal or pain killer, anti-inflammatory or so.
Nariz Anatomical Therapeutic Chemical codes:
A medicine is classified depending on the organ or system it acts [Anatomical], based on what result it gives on what disease, symptom [Therapeutical], based on chemical composition [Chemical]. It is called as ATC code. The code is based on Active ingredients of the medicine. A medicine can have different codes as sometimes it acts on different organs for different indications. Same way, different brands with same active ingredients and same indications can have same ATC code.
Nariz pharmaceutical companies:
Pharmaceutical companies are drug manufacturing companies that help in complete development of the drug from the background research to formation, clinical trials, release of the drug into the market and marketing of the drug.
Researchers are the persons who are responsible for the scientific research and is responsible for all the background clinical trials that resulted in the development of the drug.
Frequently asked QuestionsCan i drive or operate heavy machine after consuming Nariz?
Depending on the reaction of the Nariz after taken, if you are feeling dizziness, drowsiness or any weakness as a reaction on your body, Then consider Nariz not safe to drive or operate heavy machine after consumption. Meaning that, do not drive or operate heavy duty machines after taking the capsule if the capsule has a strange reaction on your body like dizziness, drowsiness. As prescribed by a pharmacist, it is dangerous to take alcohol while taking medicines as it exposed patients to drowsiness and health risk. Please take note of such effect most especially when taking Primosa capsule. It's advisable to consult your doctor on time for a proper recommendation and medical consultations.Is Nariz addictive or habit forming?
Medicines are not designed with the mind of creating an addiction or abuse on the health of the users. Addictive Medicine is categorically called Controlled substances by the government. For instance, Schedule H or X in India and schedule II-V in the US are controlled substances.
Please consult the medicine instruction manual on how to use and ensure it is not a controlled substance.In conclusion, self medication is a killer to your health. Consult your doctor for a proper prescription, recommendation, and guidiance.
Reviewsdrugs.com conducted a study on Nariz, and the result of the survey is set out below. It is noteworthy that the product of the survey is based on the perception and impressions of the visitors of the website as well as the views of Nariz consumers. We, as a result of this, advice that you do not base your therapeutic or medical decisions on this result, but rather consult your certified medical experts for their recommendations.
The information was verified by Dr. Arunabha Ray, MD Pharmacology