DRUGS & SUPPLEMENTS

Methocillin S

Name: Methocillin S drug & pharmaceuticals. Available Forms, Doses, Prices
Creator: sdrugs.com
Published: 2021-11-11T10:10:10+00:00

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Methocillin S uses

Caution:
Description:
Storage:
Action:
Indications:
Dosage for dry cows:
Directions for use:
Precautions:
Residue warnings:
How supplied:
Methocillin S reviews

NADA 055-058, Approved by FDA

Caution:

Federal law restricts this drug to use by or on the order of a licensed veterinarian.

Description:

Methocillin S (cloxacillin benzathine) for Intramammary Infusion into the Dry Cow is a product which provides bactericidal activity against gram-positive bacteria. The active agent, Methocillin S benzathine, is a sparingly soluble salt of the semisynthetic penicillin, Methocillin S. Methocillin S is a derivative of 6-aminopenicillanic acid, and therefore is chemically related to other penicillins. It has, however, the antibacterial properties described below, which distinguish it from certain other penicillins.

Each 10 mL disposable syringe contains Methocillin S benzathine equivalent to 500 mg of Methocillin S activity in a stable peanut oil gel. This product was manufactured by a non-sterilizing process.

Storage:

Do not store above 25°C (77°F). Do not freeze.

Action:

In the non-lactating mammary gland, Methocillin S (cloxacillin benzathine) provides bactericidal levels of the active antibiotic, Methocillin S, for a prolonged period of time. This prolonged activity is due to the low solubility of the Methocillin S benzathine and to the slow-release oil-gel base. This prolonged contact between the antibiotic and the pathogenic organism enhances the probability of a bacteriological cure.

Methocillin S is not destroyed by the enzyme, penicillinase, and therefore, is active against penicillin-resistant strains of Staphylococcus aureus. It is also active against non-penicillinase-producing Staphylococcus aureus as well as Streptococcus agalactiae.

The class disc, Methicillin 5 mcg, should be used to estimate the in vitro susceptibility of bacteria to Methocillin S.

Indications:

For the treatment of mastitis in dairy cows during the dry period.

Methocillin S has been shown by extensive clinical studies to be efficacious in the treatment of mastitis in dry cows, when caused by Streptococcus agalactiae and Staphylococcus aureus including penicillin-resistant strains.

Treatment of the dry cow with Methocillin S is indicated in any cow known to harbor any of these organisms in the udder at drying off, or which has had repeated attacks of mastitis during the previous lactation, or is affected with mastitis at drying off, if caused by susceptible organisms.

Dosage for Dry Cows:

Infuse the contents of one syringe (10 mL) into each quarter following the last milking. See Directions for Use.

Directions for Use:

Methocillin S (cloxacillin benzathine) is for use in dry cows only. Administer immediately after the last milking. Use no later than 30 days prior to calving.

Completely milk out all four quarters. The udder and teats should be thoroughly washed with warm water containing a suitable dairy antiseptic and dried, preferably using individual paper towels. Carefully scrub the teat end and orifice with 70% alcohol, using a separate swab for each teat. Allow to dry.

Methocillin S is packaged with the Opti-Sert^®Protective Cap.

For partial insertion: Twist off upper portion of the Opti-Sert Protective Cap to expose 3–4 mm of the syringe tip.

For full insertion: Remove protective cap to expose the full length of the syringe tip.

Insert syringe tip into the teat canal and expel the entire contents of syringe into the quarter. Withdraw the syringe and gently massage the quarter to distribute the medication.

Do not infuse contents of the mastitis syringe into the teat canal if the Opti-Sert Protective Cap is broken or damaged.

Precautions:

Because it is a derivative of 6-aminopenicillanic acid, Methocillin S has the potential for producing allergic reactions. Such reactions are rare; however, should they occur, the subject should be treated with antihistamines or pressor amines, such as epinephrine.

Residue Warnings:

1. For use in dry cows only.

2. Not to be used within 30 days of calving.

3. Any animal infused with this product must not be slaughtered for food until 30 days after the latest infusion.

How Supplied:

Methocillin S (cloxacillin benzathine) Intramammary Infusion is supplied as 10 mL syringes containing 500 mg of Methocillin S activity per syringe. One display carton contains 12 syringes. One pail contains 144 syringes.

NDC 0010-4720-01 - 10 mL syringe

NDC 0010-4720-02 - 12 syringes

NDC 0010-4720-03 - 144 syringes

Opti-Sert is a registered trademark of Zoetis W LLC - used under license.

Methocillin S is a registered trademark of Boehringer Ingelheim Vetmedica, Inc.

Made in Italy

Manufactured for:

Boehringer Ingelheim Vetmedica, Inc.

St. Joseph, MO 64506 U.S.A.

51729292

472001-03

Methocillin S pharmaceutical active ingredients containing related brand and generic drugs:

Cloxacillin

Methocillin S available forms, composition, doses:

Methocillin S destination | category:

Human:
Penicillinase-resistant penicillins
Penicillins

Methocillin S Anatomical Therapeutic Chemical codes:

J01CF02 - Cloxacillin

Methocillin S pharmaceutical companies:

References

Dailymed."CLOXACILLIN SODIUM: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailym... (accessed August 28, 2018).
"cloxacillin". https://pubchem.ncbi.nlm.nih.gov/co... (accessed August 28, 2018).
"cloxacillin". http://www.drugbank.ca/drugs/DB0114... (accessed August 28, 2018).

Frequently asked Questions

Can i drive or operate heavy machine after consuming Methocillin S?

Depending on the reaction of the Methocillin S after taken, if you are feeling dizziness, drowsiness or any weakness as a reaction on your body, Then consider Methocillin S not safe to drive or operate heavy machine after consumption. Meaning that, do not drive or operate heavy duty machines after taking the capsule if the capsule has a strange reaction on your body like dizziness, drowsiness. As prescribed by a pharmacist, it is dangerous to take alcohol while taking medicines as it exposed patients to drowsiness and health risk. Please take note of such effect most especially when taking Primosa capsule. It's advisable to consult your doctor on time for a proper recommendation and medical consultations.

Is Methocillin S addictive or habit forming?

Medicines are not designed with the mind of creating an addiction or abuse on the health of the users. Addictive Medicine is categorically called Controlled substances by the government. For instance, Schedule H or X in India and schedule II-V in the US are controlled substances.

Please consult the medicine instruction manual on how to use and ensure it is not a controlled substance.In conclusion, self medication is a killer to your health. Consult your doctor for a proper prescription, recommendation, and guidiance.

Review

sdrugs.com conducted a study on Methocillin S, and the result of the survey is set out below. It is noteworthy that the product of the survey is based on the perception and impressions of the visitors of the website as well as the views of Methocillin S consumers. We, as a result of this, advice that you do not base your therapeutic or medical decisions on this result, but rather consult your certified medical experts for their recommendations.