DRUGS & SUPPLEMENTS
How is the drug helping you?
Imovane is a sleeping drug from group of cyclopyrrolone derivatives. This drug is "non benzodiazepine" agonist of benzodiazepine receptors. Imovane also has sedative, anxiolytic, muscle-relaxing center, anticonvulsant and amnesic properties. Like a derivative of benzodiazepine Imovane enhances GABA-ergic processes in the brain, interacting with the benzodiazepine receptors, as a result of the increased sensitivity of GABA-receptors to the neurotransmitter. However, Imovane apparently interacts with other parts of the benzodiazepine receptor than benzodiazepines.
Imovane reduced sleep time, reduces the number of nighttime awakenings, increases total sleep time. This medication almost has no effect on sleep structure, does not reduce significantly the amount of REM sleep. Consequences of the phenomenon of waking up are missing or expressed little. Readmission Imovane are not accompanied by cumulation.
Imovane rapidly and completely absorbed from the gastrointestinal tract. Cmax achieved within 1-3 hours. Imovane easily passes through gistogematicheskie barriers including the BBB and it is distributed in organs and tissues including brain. T1/2 is 5.5-6 hours, not accumulates.
Sleep disturbance, transient, situational or chronic insomnia; sleep disturbances in mental disorders, bronchial asthma with nocturnal seizures (in combination with single dose daily dose of theophylline).
The average therapeutic dose of Imovane is 7.5 mg orally at night, in cases of severe insomnia the dose can be increased up to 15 mg. In elderly patients, as well as abnormal liver function is used 3.75 mg.
Digestive system: a feeling of bitter or metallic taste in the mouth, dry mouth, nausea, and vomiting.
CNS: dizziness, headache, drowsiness, confusion, anterograde amnesia, hallucinations, nightmares.
Dermatologic reactions: skin rash.
Severe respiratory failure, pregnancy, lactation, children and teens under 15 years old, hypersensitivity to Imovane.
Imovane is contraindicated during pregnancy (especially in I and III trimester) and lactation (breastfeeding). If a woman uses Imovane in III trimester of pregnancy there are possible violations of the nervous system in the newborn, the emergence of withdrawal syndrome. If the woman is prescribed by a doctor took Imovane immediately prior to labor and delivery, it needs a constant medical surveillance for the newborn. At the time of treatment it should be stoped breastfeeding (zopiclone penetrates into breast milk).
With caution use in patients with severe liver failure.
Risk of drug dependence is minimal if the duration of Imovane did not exceed 4 weeks. However, the potential danger of Imovane dependence to exist.
During the period of treatment patients should to exclude the use of alcohol.
On the next day after taking the drug it should be cautious to drive and operate machinery.
Simultaneous administration of Imovane with trimipramine reduces the concentration of trimipramine in plasma and its effect.
Imovane increases the influence of CNS depressants.
Symptoms: CNS depression of varying severity (from drowsiness to loss of consciousness).
Treatment: gastric lavage, taking activated charcoal, if necessary - symptomatic therapy. As a specific antidote used benzodiazepine receptor antagonist flumazenil (in hospital). Hemodialysis is ineffective.
Depending on the reaction of the Imovane after taken, if you are feeling dizziness, drowsiness or any weakness as a reaction on your body, Then consider Imovane not safe to drive or operate heavy machine after consumption. Meaning that, do not drive or operate heavy duty machines after taking the capsule if the capsule has a strange reaction on your body like dizziness, drowsiness. As prescribed by a pharmacist, it is dangerous to take alcohol while taking medicines as it exposed patients to drowsiness and health risk. Please take note of such effect most especially when taking Primosa capsule. It's advisable to consult your doctor on time for a proper recommendation and medical consultations.Is Imovane addictive or habit forming?
Medicines are not designed with the mind of creating an addiction or abuse on the health of the users. Addictive Medicine is categorically called Controlled substances by the government. For instance, Schedule H or X in India and schedule II-V in the US are controlled substances.
Please consult the medicine instruction manual on how to use and ensure it is not a controlled substance.In conclusion, self medication is a killer to your health. Consult your doctor for a proper prescription, recommendation, and guidiance.
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The information was verified by Dr. Rachana Salvi, MD Pharmacology