DRUGS & SUPPLEMENTS
What are the side effects you encounter while taking this medicine?
NSAIDs, a derivative of phenylpropionic acid, Ibuprofen has anti-inflammatory, analgesic and antipyretic effect.
The mechanism of action is associated with inhibition of COX activity - the main enzyme metabolism of arachidonic acid, which is a precursor of prostaglandins, which play a major role in the pathogenesis of inflammation, pain and fever. Analgesic effect is due to both peripheral, and a central mechanism (due to inhibition of prostaglandin synthesis in the central and peripheral nervous system). Inhibits platelet aggregation.
For topical use anti-inflammatory and analgesic action. Reduces morning stiffness, increased the amount of motion in joints.
When oral administered Ibuprofen almost completely absorbed from the gastrointestinal tract. Simultaneous food intake slows the rate of absorption. Metabolised in the liver (90%). T1 / 2 is 2-3 hours.
80% of the dose excreted in urine mainly as metabolites (70%), 10% - unchanged, 20% eliminated through the intestine in the form of metabolites.
Inflammatory, degenerative diseases of joints and spine, articular syndrome in patients with acute gout, psoriatic arthritis, ankylosing spondylitis, tendonitis, bursitis, sciatica, traumatic inflammation of soft tissue and musculoskeletal apparatus. Neuralgia, myalgia, pain in infectious and inflammatory diseases of ENT organs, bursitis, algomenorrhea, headache and toothache. Fever in infectious and inflammatory diseases.
Setting individually, depending on etiology of disease, severity of clinical manifestations. When administered rectally or adult single dose of 200-800 mg, the frequency of reception - 3-4; for children - 20-40 mg / kg in divided doses.
Topical applied within 2-3 weeks.
The maximum daily dose for adults when administered oral or rectally or is 2.4 g.
Oral, after a meal. Rheumatoid arthritis - by 0.8 g 3 times a day in osteoarthrosis and ankylosing spondylitis - by 0.4-0.6 g 3-4 times a day, in juvenile rheumatoid arthritis - at 30-40 mg / kg / day in several stages.
When soft tissue injuries, sprains - 1.6-2.4 g / day in divided doses.
At moderate pain syndrome - 1.2 g per day.
Digestive system: frequently - nausea, anorexia, vomiting, epigastric discomfort, diarrhea, possibly the development of erosive and ulcerative lesions of the gastrointestinal tract; rare - bleeding from the gastrointestinal tract, long-term use possible liver problems.
Central nervous system and peripheral nervous systems: frequently - headache, dizziness, sleep disturbances, agitation, visual impairment.
Hemopoietic system: long-term use may be anemia, thrombocytopenia, agranulocytosis.
Urinary tract: long-term use possible renal dysfunction.
Allergic reactions: often - skin rash, Quincke's edema, rarely - aseptic meningitis, bronchospasm syndrome.
Local reactions: when topical used may be hyperemia of the skin, burning or tingling.
Erosive-ulcerative lesions in the gastrointestinal tract exacerbation, diseases of the optic nerve, "aspirin triad", hemodyscrasia, pronounced renal dysfunction and / or liver, children age (to 6 years), hypersensitivity to Ibuprofen.
Do not use Ibuprofen in the III trimester of pregnancy. Application I and II trimesters of pregnancy is justified only in cases where the expected benefit to the mother than the possible harm to the fetus.
This medication Ibuprofen in small amounts excreted in breast milk. Possible using in lactation for pain and fever. If necessary, prolonged use or use in high doses, should decide on the termination of breastfeeding.
Precautions are used with the attendant liver and kidney diseases, chronic heart failure, with dyspeptic symptoms before treatment, immediately after surgery, with indications of a history of gastrointestinal bleeding in diseases of the digestive tract, allergic reactions associated with NSAID intake.
In the course of treatment requires systematic monitoring of the liver and kidneys, peripheral blood picture.
It should not be applied externally to the damaged skin.
With simultaneous use of Ibuprofen reduces the effect of antihypertensive agents, diuretics (furosemide, hypothiazide).
With the simultaneous use of anticoagulants may enhance their action.
With simultaneous application of SCS increases the risk of side effects from the gastrointestinal tract.
With the simultaneous application of Ibuprofen may displace from compounds with plasma proteins indirect anticoagulants (acenocoumarol), derivatives of hydantoin (phenytoin), oral hypoglycemic drugs sulfonylurea derivatives.
With the simultaneous use of amlodipine may be a slight reduction of antihypertensive action of amlodipine, with acetylsalicylic acid - decreased concentration of Ibuprofen in blood plasma, with baclofen - described a case of toxic gain of baclofen.
When applied simultaneously with warfarin may increase bleeding time, were also observed microhematuria, bruises with hydrochlorothiazide - perhaps a slight reduction of antihypertensive action of hydrochlorothiazide, captopril - may reduce antihypertensive effect of captopril, with cholestyramine - moderately decrease absorption of Ibuprofen.
With simultaneous application of lithium carbonate increased the concentration of lithium in blood plasma.
With simultaneous application of magnesium hydroxide increases the initial absorption of Ibuprofen, with methotrexate - increases the toxicity of methotrexate.
In case of overdose, call your local poison control center or emergency services.
Symptoms of overdose may include: dizziness; fast eye movements that you cannot control; slow breathing or short periods of time without breathing; blue color around the lips, mouth, and nose.
In a dry, protected from light place, at temperatures below 25°C.Common expiration date for Ibuprofen tablets: 3 years.
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|Advil 200 mg liqui-gel capsule||0.19 USD|
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|Advil cold & sinus caplet||0.22 USD|
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|Apo-Ibuprofen 300 mg Tablet||0.07 USD|
|Apo-Ibuprofen 400 mg Tablet||0.08 USD|
|Apo-Ibuprofen 600 mg Tablet||0.14 USD|
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|CVS Pharmacy ibuprofen 200 mg tablet||0.05 USD|
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|Caplets; Oral; Ibuprofen 200 mg|
|Capsules; Oral; Ibuprofen 200 mg|
|Child ibuprofen susp||0.05 USD|
|Children's medi-profen susp||0.05 USD|
|Children's motrin cold||0.04 USD|
|Children's motrin cold suspension||0.05 USD|
|Childs ibuprofen susp drp||0.33 USD|
|Dragee; Oral; Ibuprofen 200 mg|
|Eck ibuprofen jr caplet||0.17 USD|
|Eql ibuprofen 200 mg tablet||0.1 USD|
|Gel; Topical; Ibuprofen 5%|
|I-prin 200 mg tablet||0.05 USD|
|Ibu-drops 40 mg/ml suspension drops||0.42 USD|
|Ibuprofen 100 mg tablet chew||0.15 USD|
|Ibuprofen 100 mg/5ml Suspension||0.06 USD|
|Ibuprofen 200 mg caplet||0.06 USD|
|Ibuprofen 200 mg tablet||0.03 USD|
|Ibuprofen 400 mg tablet||0.35 USD|
|Ibuprofen 600 mg tablet||0.33 USD|
|Ibuprofen 800 mg tablet||0.36 USD|
|Ibuprofen cold suspension||0.05 USD|
|Ibuprofen cold-sinus caplet||0.2 USD|
|Ibuprofen ib 200 mg tablet||0.08 USD|
|Ibuprofen pm caplet||0.17 USD|
|Ibuprofen powder||1.04 USD|
|Infant ibuprofen susp drop||0.29 USD|
|Infant's motrin 50 mg/1.25 ml||0.34 USD|
|Infants medi-profen susp||0.23 USD|
|Medi-profen 200 mg tablet||0.07 USD|
|Midol caplet||0.21 USD|
|Motrin 100 mg caplet||0.2 USD|
|Motrin 100 mg tablet chew||0.18 USD|
|Motrin 400 mg tablet||0.29 USD|
|Motrin 600 mg tablet||0.4 USD|
|Motrin 800 mg tablet||0.59 USD|
|Motrin ib 200 mg caplet||0.15 USD|
|Motrin ib 200 mg gelcap||0.12 USD|
|Motrin ib 200 mg tablet||0.13 USD|
|Motrin pm caplet||0.2 USD|
|Neoprofen 20 mg/2 ml vial||304.5 USD|
|Novo-Profen 400 mg Tablet||0.08 USD|
|Novo-Profen 600 mg Tablet||0.05 USD|
|Nu-Ibuprofen 600 mg Tablet||0.14 USD|
|Nuprin 200 mg caplet||0.12 USD|
|Nuprin 200 mg tablet||0.1 USD|
|Nuprin arthritis patch||1.11 USD|
|Nuprin muscle & joint patch||1.03 USD|
|Ointment; Topical; Ibuprofen 5%|
|Profen II 45-800 mg 12 Hour tablet||0.69 USD|
|Pub infants profenib drops||0.18 USD|
|Pv ibuprofen 200 mg caplet||0.04 USD|
|Pv ibuprofen 200 mg tablet||0.02 USD|
|Sm ibuprofen ib 100 mg tablet||0.18 USD|
|Soba children's profenib susp||0.04 USD|
|Soba profen cold-sinus tablet||0.22 USD|
|Soba profen ib caplet||0.19 USD|
|Suppositories; Rectal; Ibuprofen 500 mg|
|Suppositories; Rectal; Ibuprofen 600 mg|
|Suspension; Oral; Ibuprofen 100 mg / 5 ml|
|Suspension; Oral; Ibuprofen 40 mg / ml|
|Tablets, Chewable; Oral; Ibuprofen 100 mg|
|Tablets, Chewable; Oral; Ibuprofen 50 mg|
|Tablets, Effervescent; Oral; Ibuprofen 200 mg|
|Tablets, Film-Coated; Oral; Ibuprofen|
|Tablets, Film-Coated; Oral; Ibuprofen 200 mg|
|Tablets, Film-Coated; Oral; Ibuprofen 400 mg|
|Tablets, Film-Coated; Oral; Ibuprofen 600 mg|
|Tablets, Retard; Oral; Ibuprofen 800 mg|
|Tablets, Sugar-Coated; Oral; Ibuprofen 100 mg|
|Tablets; Oral; Ibuprofen 100 mg|
|Tablets; Oral; Ibuprofen 200 mg|
|Tablets; Oral; Ibuprofen 300 mg|
|Tablets; Oral; Ibuprofen 400 mg|
|Tablets; Oral; Ibuprofen 600 mg|
|Tablets; Oral; Ibuprofen 800 mg|
|Wal-profen 200 mg caplet||0.12 USD|
|Wal-profen 200 mg tablet||0.12 USD|
|Wal-profen cold & sinus cplt||0.3 USD|
Depending on the reaction of the Ibuprofen after taken, if you are feeling dizziness, drowsiness or any weakness as a reaction on your body, Then consider Ibuprofen not safe to drive or operate heavy machine after consumption. Meaning that, do not drive or operate heavy duty machines after taking the capsule if the capsule has a strange reaction on your body like dizziness, drowsiness. As prescribed by a pharmacist, it is dangerous to take alcohol while taking medicines as it exposed patients to drowsiness and health risk. Please take note of such effect most especially when taking Primosa capsule. It's advisable to consult your doctor on time for a proper recommendation and medical consultations.Is Ibuprofen addictive or habit forming?
Medicines are not designed with the mind of creating an addiction or abuse on the health of the users. Addictive Medicine is categorically called Controlled substances by the government. For instance, Schedule H or X in India and schedule II-V in the US are controlled substances.
Please consult the medicine instruction manual on how to use and ensure it is not a controlled substance.In conclusion, self medication is a killer to your health. Consult your doctor for a proper prescription, recommendation, and guidiance.
|No side effects||2||66.7%|
|It has side effects||1||33.3%|
|Once in a day||4||66.7%|
|3 times in a day||1||16.7%|
|4 times in a day||1||16.7%|
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The information was verified by Dr. Rachana Salvi, MD Pharmacology