DRUGS & SUPPLEMENTS
Forverm usesForverm consists of Mebendazole, Thiabendazole.
Forverm is a worming medication a broad spectrum of action, it is most effective when enterobioze. This drug causes irreversible disturbance of glucose utilization in the body of the worm and inhibits the synthesis of ATP.
Forverm (Mebendazole) is practically not absorbed from the gastrointestinal tract. The plasma protein binding is 90%. This medication is distributed unevenly in organs and accumulates in adipose tissue, liver, and larvae of helminths. Forverm (Mebendazole) is metabolized in the liver to 2-amino derivative.
T1/2 is 2.5-5.5 hours. More than 90% of the dose is excreted unchanged in feces. Grown deep portion (5-10%) is excreted by kidneys.
Why is Forverm prescribed?
Enterobiasis, ascariasis, hookworm disease, strongyloidiasis, trichuriasis, trichinosis, teniasis, echinococcosis, mixed helminth infections.
Dosage and administration
For adults and children over 10 years at enterobioze a single dose is 100 mg.
For children aged 2 to 10 years a single dose is 25-50 mg. In the case of a high probability of re-infestation the drug taking repeats after 2-4 weeks in the same dose.
It is recommended that simultaneous treatment of all family members.
When ascariasis, trichuriasis, hookworm disease, teniasis, strongyloidiasis and mixed helminthiasis - 100 mg in the morning and evening for 3 days. When trichinosis - 200-400 mg 3 times / day for 3 days, from 4th to 10th day - 400-500 mg 3 times / day. When echinococcosis - 500 mg 2 times / day in the first 3 days, then the same dose 3 times / day in the next 3 days. Later Forverm used in doses of 25-30 mg / kg / day in 3-4 doses.
Forverm (Mebendazole) side effects, adverse reactions
Digestive system: rarely - nausea, abdominal pain; when used in high doses for long periods of time may be vomiting, diarrhea, transient elevation of liver enzymes in serum.
CNS: Rarely - dizziness when used in high doses for long periods of time - a headache.
Hematopoietic system: when used in high doses for long periods of time may be leukopenia, anemia, eosinophilia.
Urinary system: when used in high doses for long periods of time - hematuria, cylindruria.
Other: when used in high doses for long periods of time - an allergic reaction, hair loss.
Pronounced liver disfunctions, pregnancy, lactation (breastfeeding), children under 2 years of age, hypersensitivity to Forverm (Mebendazole).
Using during pregnancy and breastfeeding
Forverm is contraindicated during pregnancy and lactation (breastfeeding).
Category of the fetus by FDA - C.
With prolonged use of Forverm (Mebendazole) it is necessary to control the peripheral blood picture, liver and kidney function.
Within days after taking Forverm (Mebendazole) avoid drinking alcohol.
After receiving Forverm (Mebendazole) do not use a laxative.
It is mandatory a periodic examination of smears of the anal region and the feces after treatment (therapy is effective in the absence of helminths or their eggs for 7 consecutive days).
Forverm drug interactions
Forverm (Mebendazole) reduces insulin requirements in diabetic patients.
It is necessary to avoid a simultaneously taking of Forverm (Mebendazole) with lipophilic substances. With simultaneous use with cimetidine it may increase, and carbamazepine, and other inducers of metabolism to reduce the concentration of Forverm (Mebendazole) in the blood.
Forverm in case of emergency / overdose
Symptoms: nausea, vomiting, diarrhea, abdominal pain. With prolonged use at high doses: reversible hepatic dysfunction, hepatitis, neutropenia.
Treatment: gastric lavage, enemas, activated charcoal method; there is no specific antidote.
2-Substituted benzimidazole first introduced in 1962. It is active against a variety of nematodes and is the drug of choice for strongyloidiasis. It has CNS side effects and hepatototoxic potential. (From Smith and Reynard, Textbook of Pharmacology, 1992, p919)
Indication: For the treatment of strongyloidiasis (threadworm), cutaneous larva migrans (creeping eruption), visceral larva migrans, and trichinosis.
Forverm (Thiabendazole) is a fungicide and parasiticide. Forverm (Thiabendazole) is also a chelating agent, which means that it is used medicinally to bind metals in cases of metal poisoning, such as lead poisoning, mercury poisoning or antimony poisoning. Forverm (Thiabendazole) is vermicidal and/or vermifugal against Ascaris lumbricoides ("common roundworm"), Strongyloides stercoralis (threadworm), Necator americanus, Ancylostoma duodenale (hookworm), Trichuris trichiura (whipworm), Ancylostoma braziliense (dog and cat hookworm), Toxocara canis, Toxocara cati (ascarids), and Enterobius vermicularis (pinworm). Forverm (Thiabendazole) also suppresses egg and/or larval production and may inhibit the subsequent development of those eggs or larvae which are passed in the feces.
Forverm pharmaceutical active ingredients containing related brand and generic drugs:
Active ingredient is the part of the drug or medicine which is biologically active. This portion of the drug is responsible for the main action of the drug which is intended to cure or reduce the symptom or disease. The other portions of the drug which are inactive are called excipients; there role is to act as vehicle or binder. In contrast to active ingredient, the inactive ingredient's role is not significant in the cure or treatment of the disease. There can be one or more active ingredients in a drug.
Forverm available forms, composition, doses:
Form of the medicine is the form in which the medicine is marketed in the market, for example, a medicine X can be in the form of capsule or the form of chewable tablet or the form of tablet. Sometimes same medicine can be available as injection form. Each medicine cannot be in all forms but can be marketed in 1, 2, or 3 forms which the pharmaceutical company decided based on various background research results.
Composition is the list of ingredients which combinedly form a medicine. Both active ingredients and inactive ingredients form the composition. The active ingredient gives the desired therapeutic effect whereas the inactive ingredient helps in making the medicine stable.
Doses are various strengths of the medicine like 10mg, 20mg, 30mg and so on. Each medicine comes in various doses which is decided by the manufacturer, that is, pharmaceutical company. The dose is decided on the severity of the symptom or disease.
Forverm destination | category:
Destination is defined as the organism to which the drug or medicine is targeted. For most of the drugs what we discuss, human is the drug destination.
Drug category can be defined as major classification of the drug. For example, an antihistaminic or an antipyretic or anti anginal or pain killer, anti-inflammatory or so.
Forverm Anatomical Therapeutic Chemical codes:
A medicine is classified depending on the organ or system it acts [Anatomical], based on what result it gives on what disease, symptom [Therapeutical], based on chemical composition [Chemical]. It is called as ATC code. The code is based on Active ingredients of the medicine. A medicine can have different codes as sometimes it acts on different organs for different indications. Same way, different brands with same active ingredients and same indications can have same ATC code.
Forverm pharmaceutical companies:
Pharmaceutical companies are drug manufacturing companies that help in complete development of the drug from the background research to formation, clinical trials, release of the drug into the market and marketing of the drug.
Researchers are the persons who are responsible for the scientific research and is responsible for all the background clinical trials that resulted in the development of the drug.
Frequently asked QuestionsCan i drive or operate heavy machine after consuming Forverm?
Depending on the reaction of the Forverm after taken, if you are feeling dizziness, drowsiness or any weakness as a reaction on your body, Then consider Forverm not safe to drive or operate heavy machine after consumption. Meaning that, do not drive or operate heavy duty machines after taking the capsule if the capsule has a strange reaction on your body like dizziness, drowsiness. As prescribed by a pharmacist, it is dangerous to take alcohol while taking medicines as it exposed patients to drowsiness and health risk. Please take note of such effect most especially when taking Primosa capsule. It's advisable to consult your doctor on time for a proper recommendation and medical consultations.Is Forverm addictive or habit forming?
Medicines are not designed with the mind of creating an addiction or abuse on the health of the users. Addictive Medicine is categorically called Controlled substances by the government. For instance, Schedule H or X in India and schedule II-V in the US are controlled substances.
Please consult the medicine instruction manual on how to use and ensure it is not a controlled substance.In conclusion, self medication is a killer to your health. Consult your doctor for a proper prescription, recommendation, and guidiance.
ReviewsDrugs.com conducted a study on Forverm, and the result of the survey is set out below. It is noteworthy that the product of the survey is based on the perception and impressions of the visitors of the website as well as the views of Forverm consumers. We, as a result of this, advice that you do not base your therapeutic or medical decisions on this result, but rather consult your certified medical experts for their recommendations.
The information was verified by Dr. Arunabha Ray, MD Pharmacology