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DRUGS & SUPPLEMENTS
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Dermochinona
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Dermochinona uses
- Indications and usage
- Contraindications
- Warnings
- Precautions
- Adverse reactions
- Dosage and administration
- How supplied
INDICATIONS AND USAGE
Dermochinona Cream 20% is indicated for final depigmentation in extensive Vitiligo.
Dermochinona Cream 20% is applied topically to permanently depigment normal skin surrounding vitiliginous lesions in patients with disseminated (greater than 50 percent of body surface area) idiopathic vitiligo. Benoquin Cream 20% is not recommended in freckling; hyperpigmentation caused by photosensitization following the use of certain perfumes (berlock dermatitis); melasma (chloasma) of pregnancy; or hyperpigmentation resulting from inflammation of the skin. Dermochinona Cream 20% is not effective for the treatment of cafe-au-lait spots, pigmented nevi, malignant melanoma or pigmentation resulting from pigments other than melanin (e.g.: bile, silver, or artificial pigments).
CONTRAINDICATIONS
Dermochinona Cream 20% contains a potent depigmenting agent and is not a cosmetic skin bleach. Use of Dermochinona Cream 20% is contraindicated in any conditions other than disseminated vitiligo. Dermochinona Cream 20% frequently produces irreversible depigmentation, and it must not be used as a substitute for hydroquinone.
Dermochinona Cream 20% is also contraindicated in individuals with a history of sensitivity or allergic reactions to this product, or any of its ingredients.
WARNINGS
Dermochinona Cream 20% is a potent depigmenting agent, not a mild cosmetic bleach. Do not use except for final depigmentation in extensive vitiligo.
Keep this, and all medications out of the reach of children. In case of accidental ingestion, call a physician or a Poison Control Center immediately.
PRECAUTIONS
:
General
Dermochinona Cream 20% is for External Use Only. Following therapy with Dermochinona Cream 20%, the skin will be sensitive for the rest of the patient’s life. He/she must use sunscreens during exposure to the sun.
Information for the Patient
Dermochinona Cream 20% contains a potent depigmenting agent and is not a cosmetic skin bleach. Use of Dermochinona Cream 20% is contraindicated in any conditions other than disseminated vitiligo. Use only for final depigmentation in extensive vitiligo. Areas of normal skin distant to the site of Dermochinona Cream 20% application may become depigmented, and irregular, excessive, unsightly, and frequently permanent depigmentation may occur.
Carcinogenesis, mutagenesis, impairment of fertility
No long term studies have been performed to evaluate carcinogenic potential.
Pregnancy: Category C
Animal reproduction studies have not been conducted with Dermochinona Cream 20%. It is also not known whether Dermochinona Cream 20% can cause fetal harm when administered to a pregnant woman, or can affect reproduction capacity. Dermochinona Cream 20% should be given to a pregnant woman only if clearly needed.
Nursing Mothers
It is not known whether this drug is excreted in human milk. Because many drugs are excreted in human milk, caution should be exercised when Dermochinona Cream 20% is administered to a nursing woman.
Pediatric Use
The safety and effectiveness of Dermochinona Cream 20% in pediatric patients below the age of 12 years have not been established.
ADVERSE REACTIONS
Mild, transient skin irritation and sensitization, including erythematous and eczematous reactions have occurred following topical application of Dermochinona Cream 20%. Although those reactions are usually transient, treatment with Dermochinona Cream 20% should be discontinued if irritation, a burning sensation, or dermatitis occur. Areas of normal skin distant to the site of Dermochinona Cream 20% application frequently have become depigmented, and irregular, excessive, unsightly, and frequently permanent depigmentation has occurred.
DOSAGE AND ADMINISTRATION
A thin layer of Dermochinona Cream 20% should be applied and rubbed into the pigmented area two or three times daily, or as directed by physician. Prolonged exposure to sunlight should be avoided during treatment with Dermochinona Cream 20%, or a sunscreen should be used.
Depigmentation is usually accomplished after one to four months of Dermochinona Cream 20% treatment. If satisfactory results are not obtained after four months of Dermochinona Cream 20% treatment, the drug should be discontinued. When the desired degree of depigmentation is obtained, Dermochinona Cream 20% should be applied only as often as needed to maintain depigmentation (usually only two times weekly).
HOW SUPPLIED
Dermochinona Cream 20% in 1 1/4 oz. tubes (35.4 g)
(NDC 0187-0380-34).
Dermochinona Cream 20% should be stored at 25°C (77°F);
excursion permitted to 15°C - 30°C (59°F - 86°F).
ICN Pharmaceuticals, Inc.
3300 Hyland Ave.
Costa Mesa, CA 92626
(714)545-01002393-05 EL
Rev. 8-00
Dermochinona pharmaceutical active ingredients containing related brand and generic drugs:
Dermochinona available forms, composition, doses:
Composition is the list of ingredients which combinedly form a medicine. Both active ingredients and inactive ingredients form the composition. The active ingredient gives the desired therapeutic effect whereas the inactive ingredient helps in making the medicine stable.
Doses are various strengths of the medicine like 10mg, 20mg, 30mg and so on. Each medicine comes in various doses which is decided by the manufacturer, that is, pharmaceutical company. The dose is decided on the severity of the symptom or disease.