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DRUGS & SUPPLEMENTS
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Contac Cold Nasal Congestion-Nighttime
How long you have been taking the medicine? |
Contac Cold Nasal Congestion-Nighttime uses
Contac Cold Nasal Congestion-Nighttime consists of Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hydrobromide, Pseudoephedrine Hydrochloride.Acetaminophen:
Pharmacological action
Contac Cold Nasal Congestion-Nighttime is an analgesic-antipyretic. It has analgesic, antipyretic and weak anti-inflammatory action. The mechanism of action is associated with inhibition of prostaglandin synthesis, the predominant influence on the thermoregulation center in the hypothalamus, enhances heat transfer.
Why is Contac Cold Nasal Congestion-Nighttime (Acetaminophen) prescribed?
Pain weak and moderate intensity of different genesis (including headache, migraine, toothache, neuralgia, myalgia, algomenorrhea; pain in trauma, burns). Fever in infectious and inflammatory diseases.
Contac Cold Nasal Congestion-Nighttime dosage and administration
Oral or rectally adults and adolescents with a body weight over 60 kg is used in a single dose of 500 mg, the multiplicity of admission - up to 4 times / Maximum duration of treatment - 5-7 days.
Maximum dose: single - 1 g, daily - 4 g.
Single dose for oral administration for children aged 6-12 years - 250-500 mg, 1-5 years - 120-250 mg, from 3 months to 1 year - 60-120 mg, up to 3 months - 10 mg / kg. Single dose rectal in children aged 6-12 years - 250-500 mg, 1-5 years - 125-250 mg.
Multiplicity - 4 at intervals of not less than 4 h. The maximum duration of treatment - 3 days.
Maximum dose: 4 single dose per day.
Contac Cold Nasal Congestion-Nighttime side effects, adverse reactions
Digestive system: rarely - dyspepsia; long-term use at high doses - hepatotoxic effects, methemoglobinemia, renal dysfunction and liver, hypochromic anemia. Hemopoietic system: rarely - thrombocytopenia, leukopenia, pancytopenia, neutropenia, agranulocytosis. Allergic reactions: rarely - skin rash, itching, hives.
Contraindications
Chronic active alcoholism, increased sensitivity to Contac Cold Nasal Congestion-Nighttime, marked disturbances of liver function and / or kidney disease, anemia, pregnancy (I term).
Using during pregnancy and breastfeeding
Contac Cold Nasal Congestion-Nighttime (Acetaminophen) crosses the placental barrier. So far, no observed adverse effects of Contac Cold Nasal Congestion-Nighttime (Acetaminophen) on the fetus in humans.
Contac Cold Nasal Congestion-Nighttime (Acetaminophen) is excreted in breast milk: the content in milk was 0.04-0.23% of the dose adopted mother.
If necessary, use of Contac Cold Nasal Congestion-Nighttime (Acetaminophen) during pregnancy and lactation (breastfeeding) should carefully weigh the potential benefits of therapy for the mother and the potential risk to the fetus or child.
In experimental studies found no embryotoxic, teratogenic and mutagenic action of Contac Cold Nasal Congestion-Nighttime (Acetaminophen).
Special Instructions
Contac Cold Nasal Congestion-Nighttime is used with caution in patients with disorders of the liver and kidneys, with benign hyperbilirubinemia, as well as in elderly patients.
With prolonged use of Contac Cold Nasal Congestion-Nighttime (Acetaminophen) is necessary to monitor patterns of peripheral blood and functional state of the liver.
Used for treatment of premenstrual tension syndrome in combination with pamabrom (diuretic, a derivative of xanthine) and mepyramine (Histamine H1-receptors blocker).
Contac Cold Nasal Congestion-Nighttime (Acetaminophen) Drug Interactions
With the simultaneous use with inducers of microsomal liver enzymes, means having hepatotoxic effect, increasing the risk of hepatotoxic action of Contac Cold Nasal Congestion-Nighttime (Acetaminophen).
With the simultaneous use of anticoagulants may be slight to moderate increase in prothrombin time.
With the simultaneous use of anticholinergics may decrease absorption of Contac Cold Nasal Congestion-Nighttime (Acetaminophen).
With the simultaneous use of oral contraceptives accelerated excretion of Contac Cold Nasal Congestion-Nighttime (Acetaminophen) from the body and may reduce its analgesic action.
With the simultaneous use with urological means reduced their effectiveness.
With the simultaneous use of activated charcoal reduced bioavailability of Contac Cold Nasal Congestion-Nighttime (Acetaminophen).
When Contac Cold Nasal Congestion-Nighttime (Acetaminophen) applied simultaneously with diazepam may decrease excretion of diazepam.
There have been reports about the possibility of enhancing mielodepression effect of zidovudine while applying with Contac Cold Nasal Congestion-Nighttime (Acetaminophen). A case of severe toxic liver injury.
Described cases of toxic effects of Contac Cold Nasal Congestion-Nighttime (Acetaminophen), while the use of isoniazid.
When applied simultaneously with carbamazepine, phenytoin, phenobarbital, primidonom decreases the effectiveness of Contac Cold Nasal Congestion-Nighttime (Acetaminophen), which is caused by an increase in its metabolism and excretion from the body. Cases of hepatotoxicity, while the use of Contac Cold Nasal Congestion-Nighttime (Acetaminophen) and phenobarbital.
In applying cholestyramine a period of less than 1 h after administration of Contac Cold Nasal Congestion-Nighttime (Acetaminophen) may decrease of its absorption.
At simultaneous application with lamotrigine moderately increased excretion of lamotrigine from the body.
With the simultaneous use of metoclopramide may increase absorption of Contac Cold Nasal Congestion-Nighttime (Acetaminophen) and its increased concentration in blood plasma.
When applied simultaneously with probenecid may decrease clearance of Contac Cold Nasal Congestion-Nighttime (Acetaminophen), with rifampicin, sulfinpyrazone - may increase clearance of Contac Cold Nasal Congestion-Nighttime (Acetaminophen) due to increasing its metabolism in the liver.
At simultaneous application of Contac Cold Nasal Congestion-Nighttime (Acetaminophen) with ethinylestradiol increases absorption of Contac Cold Nasal Congestion-Nighttime (Acetaminophen) from the gut.
Enhances the effect of indirect anticoagulants (coumarin derivatives and indandione). Antipyretic and analgesic activity of caffeine increases, reduce - rifampicin, phenobarbital and alcohol (accelerated biotransformation, inducing microsomal liver enzymes).
Contac Cold Nasal Congestion-Nighttime in case of emergency / overdose
At a reception in toxic doses (10-15 g in adults) may develop liver necrosis.
Symptoms of overdose may include: nausea, vomiting, loss of appetite, sweating, extreme tiredness, unusual bleeding or bruising, pain in the upper right part of the stomach, yellowing of the skin or eyes, flu-like symptoms
Chlorpheniramine Maleate:
Drug Facts
| Active Ingredients (in each 1 mL dropperful) | Purpose |
|---|---|
| Contac Cold Nasal Congestion-Nighttime (Chlorpheniramine Maleate) Maleate 2 mg | Antihistamine |
| Phenylephrine HCl 5 mg | Nasal Decongestant |
Uses
temporarily relieves these symptoms due to the common cold, hay fever (allergic rhinitis) or other upper respiratory allergies
- runny nose
- sneezing
- itching of the nose or throat
- itchy, watery eyes
- nasal congestion
- reduces swelling of nasal passages
Warnings
Do not exceed recommended dosage.
Do not use this product in a child who is
- now taking a prescription monoamine oxidase inhibitor (certain drugs for depression, psychiatric, or emotional conditions, or Parkinson's disease), or for 2 weeks after stopping the MAOI drug. If you do not know if your child's prescription drug contains an MAOI, ask a doctor or pharmacist before giving this product.
Ask a doctor before use if a child has
- a breathing problem such as chronic bronchitis
- glaucoma
- heart disease
- high blood pressure
- thyroid disease
- diabetes mellitus
Ask a doctor before use if a child is taking sedatives or tranquilizers
When using this product
- excitability may occur, especially in children
- may cause drowsiness
- sedatives and tranquilizers may increase drowsiness effect
Stop use and ask a doctor if
- nervousness, dizziness, or sleeplessness occur
- new symptoms occur
Keep out of reach of children. In case of accidental overdose, seek professional help or contact a Poison Control Center immediately.
Directions
Do not exceed recommended dosage.
| Children 6 to under 12 years of age: | 1 mL (1 dropperful) every 4 hours, not to exceed 6 mL in 24 hours or as directed by a doctor |
| Children 2 to under 6 years of age: | 0.5 mL (1/2 dropperful) every 4 hours, not to exceed 3 mL in 24 hours, or as directed by a doctor |
| Children under 2 years of age: | Consult a doctor |
Other information
Store at 59°-86°F (15°-30°C)
Inactive ingredients
Applesauce Flavor, Citric Acid, FD&C Blue #1, FD&C Yellow #6, Glycerin, Methyl Paraben, Potassium Citrate, Potassium Sorbate, Propyl Paraben, Propylene Glycol, Purified Water, Sucralose
Questions? Comments?
Call 1-800-543-9560
Rev. 05/11
E
NEW
FORMULA
NDC 00485-0096-02
Contac Cold Nasal Congestion-Nighttime (Chlorpheniramine Maleate)
Pediatric Drops
Antihistamine ▪ Nasal Decongestant
Sugar Free ▪ Alcohol Free ▪ Gluten Free
FOR PROFESSIONAL USE ONLY
Each 1 mL for oral administration
contains:
Contac Cold Nasal Congestion-Nighttime (Chlorpheniramine Maleate) Maleate
2 mg
Phenylephrine HCl
5 mg
APPLESAUCE FLAVOR
Tamper evident by foil seal under cap.
Do not use if foil seal is broken or missing.
Manufactured for:
EDWARDS
Pharmaceuticals, Inc.
Ripley, MS 38663
2 fl. oz. (60 mL)
Dextromethorphan Hydrobromide:
Pharmacological action
Contac Cold Nasal Congestion-Nighttime is an antitussive medication. Inhibiting the excitability of the cough center this medicine suppresses the cough of any origin. Contac Cold Nasal Congestion-Nighttime (Dextromethorphan Hydrobromide) has not addiction effects and it has no analgesic and hypnotic action. Contac Cold Nasal Congestion-Nighttime (Dextromethorphan Hydrobromide) starts to act after 10-30 minutes after oral administration, the duration of therapeutic action: 5-6 hours for adults and 6-9 hours for children. Contac Cold Nasal Congestion-Nighttime (Dextromethorphan Hydrobromide) is an optical isomer of levomethorphan which is similar to morphine. Due to optical isomerism this drug has no opioid effects. Contac Cold Nasal Congestion-Nighttime (Dextromethorphan Hydrobromide) used mainly for replacement of codeine as a cough suppressant. In addition to the cough suppressant this medication is used in medicine for diagnostic purposes and may be useful in various cases - from seizures to heroin addiction treatment, some chronic neurodegenerative diseases. These include amyotrophic lateral sclerosis (ALS) (Charcot's disease), disease of "mad cow and other prion diseases. Contac Cold Nasal Congestion-Nighttime (Dextromethorphan Hydrobromide) has also been used for the treatment of mental retardation, Parkinson's disease, in the treatment of lung and other cancers and to prevent tissue rejection in transplantation because of the (poorly known) effects of sigma ligands on tumor cells and immune system.
Pharmacokinetics
After oral administration Contac Cold Nasal Congestion-Nighttime (Dextromethorphan Hydrobromide) is completely absorbed from the gastrointestinal tract. Cmax of Contac Cold Nasal Congestion-Nighttime (Dextromethorphan Hydrobromide) in plasma is reached after 2 h. This medication biotransformes in the liver. Up to 45% of this drug is excreted by kidneys and there was considerable individual variation in rates of excretion of individual metabolites.
Why is Contac Cold Nasal Congestion-Nighttime prescribed?
Dry cough of different etiology.
Dosage and administration
For adults and children over 12 years Contac Cold Nasal Congestion-Nighttime prescribed on 15 mg 4 times / day, children aged 6 years - 7.5 mg 4 times / day.
Contac Cold Nasal Congestion-Nighttime (Dextromethorphan Hydrobromide) side effects, adverse reactions
Drowsiness, nausea, dizziness.
Contac Cold Nasal Congestion-Nighttime contraindications
Bronchial asthma, bronchitis, simultaneous reception of mucolytic.
Using during pregnancy and breastfeeding
During pregnancy and lactation (breastfeeding) Contac Cold Nasal Congestion-Nighttime (Dextromethorphan Hydrobromide) prescribed with caution, only in cases where the expected therapeutic effect for the mother outweighs the potential risk to the fetus or child.
Special instructions
With carefully administered Contac Cold Nasal Congestion-Nighttime (Dextromethorphan Hydrobromide) with impaired liver function.
Contac Cold Nasal Congestion-Nighttime drug interactions
MAO inhibitors (including furazolidone, procarbazine, selegiline) when administered simultaneous with Contac Cold Nasal Congestion-Nighttime (Dextromethorphan Hydrobromide) may cause adrenergic crisis, collapse, coma, dizziness, agitation, increased blood pressure, hyperpyrexia, intracranial hemorrhage, lethargy, nausea, cramps, tremor. In combination with tricyclic antidepressants (amitriptyline, etc.) Contac Cold Nasal Congestion-Nighttime (Dextromethorphan Hydrobromide) may appeal serotonin syndrome and possible subsequent death. Amiodarone, fluoxetine, quinidine, inhibiting system cytochrome P450, may increase the drug concentration in the blood. Tobacco smoke can lead to increased secretion of glands in the background of inhibition of cough reflex. Some inhibitors of CYP450 (such as quinidine) increase and extended effects of this medicine.
Contac Cold Nasal Congestion-Nighttime in case of emergency / overdose
Symptoms: excitement, dizziness, respiratory depression, impaired consciousness, decreased blood pressure, tachycardia, muscle hypertonicity, ataxia.
Treatment: mechanical ventilation, symptomatic agents.
Pseudoephedrine Hydrochloride:
Active ingredients (in each caplet)...Purpose
Guaifenesin 400 mg...Expectorant
Contac Cold Nasal Congestion-Nighttime (Pseudoephedrine Hydrochloride) hydrochloride 60 mg...Nasal decongestant
Uses
For temporarily relief of nasal congestion due to a cold, hay fever, or other upper respiratory allergies (allergic rhinitis), and to help loosen phlegm (mucus) and thin bronchial secretions to rid the bronchial passageways of bothersome mucus and make coughs more productive.
Uses
- temporarily relieves nasal congestion due to a cold, hay fever, or other upper respiratory allergies (allergic rhinitis).
- helps loosen phlegm (mucus) and thin bronchial secretions to rid the bronchial passageways of bothersome mucus and make coughs more productive.
Warnings
Do not exceed recommended dosage.
Do not use if you are taking a prescription monoamine oxidase inhibitor (MAOI) (certain drugs for depression, psychiatric, or emotional conditions, or Parkinson's disease), or for two weeks after stopping the MAOI. If you do not know if your prescription drug contains an MAOI, ask a doctor or pharmacist before taking this product.
Do not take this product for persistent or chronic cough such as occurs with smoking, asthma, chronic bronchitis, or emphysema, or where cough is accompanied by excessive phlegm (mucus) unless directed by a doctor.
A persistent cough may be a sign of a serious condition. If cough persists for more than 1 week, tends to recur, or is accompanied by fever, rash, or persistent headache, consult a doctor.
Ask a doctor before use if you have
- heart disease
- high blood pressure
- thyroid disease
- diabetes
- difficulty in urinating due to an enlarged prostate gland
Stop use and ask a doctor if
- you get nervous, dizzy, or sleepless
- symptoms do not improve within 7 days or are accompanied by fever
If pregnant or breast-feeding, ask a health professional before use.
Keep this and all drugs out of reach of children. In case of overdose, get medical help or contact a poison control center immediately.
Directions
- adults and children 12 years and older, 1 caplet every 4 to 6 hours, not more than 4 caplets in 24 hours
- children 6 to under 12 years, ½ caplet every 4 to 6 hours, not more than 2 caplets in 24 hours
- children under 6 years, consult a physician
Inactive ingredients
croscarmellose sodium, hypromellose, magnesium stearate, microcrystalline cellulose, polyethylene glycol, povidone, sodium starch glycolate, and starch
Questions?
1-800-324-1880, 7:30am - 4:00pm Central, Mon.-Fri., or visit us at www.bfascher.com
Contac Cold Nasal Congestion-Nighttime
Contac Cold Nasal Congestion-Nighttime pharmaceutical active ingredients containing related brand and generic drugs:
Contac Cold Nasal Congestion-Nighttime available forms, composition, doses:
Contac Cold Nasal Congestion-Nighttime destination | category:
Contac Cold Nasal Congestion-Nighttime Anatomical Therapeutic Chemical codes:
Contac Cold Nasal Congestion-Nighttime pharmaceutical companies:
References
- Dailymed."SUDOGEST (PSEUDOEPHEDRINE HYDROCHLORIDE) TABLET, FILM COATED [MAJOR PHARMACEUTICALS]". https://dailymed.nlm.nih.gov/dailym... (accessed August 28, 2018).
- Dailymed."ADULT WAL TUSSIN COUGH LONG ACTING (DEXTROMETHORPHAN HYDROBROMIDE) SOLUTION [WALGREEN COMPANY]". https://dailymed.nlm.nih.gov/dailym... (accessed August 28, 2018).
- Dailymed."FEVERALL INFANTS (ACETAMINOPHEN) SUPPOSITORY [ACTAVIS MID ATLANTIC LLC]". https://dailymed.nlm.nih.gov/dailym... (accessed August 28, 2018).
Frequently asked Questions
Can i drive or operate heavy machine after consuming Contac Cold Nasal Congestion-Nighttime?Depending on the reaction of the Contac Cold Nasal Congestion-Nighttime after taken, if you are feeling dizziness, drowsiness or any weakness as a reaction on your body, Then consider Contac Cold Nasal Congestion-Nighttime not safe to drive or operate heavy machine after consumption. Meaning that, do not drive or operate heavy duty machines after taking the capsule if the capsule has a strange reaction on your body like dizziness, drowsiness. As prescribed by a pharmacist, it is dangerous to take alcohol while taking medicines as it exposed patients to drowsiness and health risk. Please take note of such effect most especially when taking Primosa capsule. It's advisable to consult your doctor on time for a proper recommendation and medical consultations.
Is Contac Cold Nasal Congestion-Nighttime addictive or habit forming?Medicines are not designed with the mind of creating an addiction or abuse on the health of the users. Addictive Medicine is categorically called Controlled substances by the government. For instance, Schedule H or X in India and schedule II-V in the US are controlled substances.
Please consult the medicine instruction manual on how to use and ensure it is not a controlled substance.In conclusion, self medication is a killer to your health. Consult your doctor for a proper prescription, recommendation, and guidiance.
Review
sdrugs.com conducted a study on Contac Cold Nasal Congestion-Nighttime, and the result of the survey is set out below. It is noteworthy that the product of the survey is based on the perception and impressions of the visitors of the website as well as the views of Contac Cold Nasal Congestion-Nighttime consumers. We, as a result of this, advice that you do not base your therapeutic or medical decisions on this result, but rather consult your certified medical experts for their recommendations.Visitor reports
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The information was verified by Dr. Rachana Salvi, MD Pharmacology