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DRUGS & SUPPLEMENTS
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Cofaid-DC
When are you taking this medicine? |
Cofaid-DC uses
Cofaid-DC consists of Chlorpheniramine, Dextromethorphan, Menthol, Phenylephrine.Chlorpheniramine:
Drug Facts
| Active Ingredients (in each 1 mL dropperful) | Purpose |
|---|---|
| Cofaid-DC (Chlorpheniramine) Maleate 2 mg | Antihistamine |
| Phenylephrine HCl 5 mg | Nasal Decongestant |
Uses
temporarily relieves these symptoms due to the common cold, hay fever (allergic rhinitis) or other upper respiratory allergies
- runny nose
- sneezing
- itching of the nose or throat
- itchy, watery eyes
- nasal congestion
- reduces swelling of nasal passages
Warnings
Do not exceed recommended dosage.
Do not use this product in a child who is
- now taking a prescription monoamine oxidase inhibitor (certain drugs for depression, psychiatric, or emotional conditions, or Parkinson's disease), or for 2 weeks after stopping the MAOI drug. If you do not know if your child's prescription drug contains an MAOI, ask a doctor or pharmacist before giving this product.
Ask a doctor before use if a child has
- a breathing problem such as chronic bronchitis
- glaucoma
- heart disease
- high blood pressure
- thyroid disease
- diabetes mellitus
Ask a doctor before use if a child is taking sedatives or tranquilizers
When using this product
- excitability may occur, especially in children
- may cause drowsiness
- sedatives and tranquilizers may increase drowsiness effect
Stop use and ask a doctor if
- nervousness, dizziness, or sleeplessness occur
- new symptoms occur
Keep out of reach of children. In case of accidental overdose, seek professional help or contact a Poison Control Center immediately.
Directions
Do not exceed recommended dosage.
| Children 6 to under 12 years of age: | 1 mL (1 dropperful) every 4 hours, not to exceed 6 mL in 24 hours or as directed by a doctor |
| Children 2 to under 6 years of age: | 0.5 mL (1/2 dropperful) every 4 hours, not to exceed 3 mL in 24 hours, or as directed by a doctor |
| Children under 2 years of age: | Consult a doctor |
Other information
Store at 59°-86°F (15°-30°C)
Inactive ingredients
Applesauce Flavor, Citric Acid, FD&C Blue #1, FD&C Yellow #6, Glycerin, Methyl Paraben, Potassium Citrate, Potassium Sorbate, Propyl Paraben, Propylene Glycol, Purified Water, Sucralose
Questions? Comments?
Call 1-800-543-9560
Rev. 05/11
E
NEW
FORMULA
NDC 00485-0096-02
Cofaid-DC (Chlorpheniramine)
Pediatric Drops
Antihistamine ▪ Nasal Decongestant
Sugar Free ▪ Alcohol Free ▪ Gluten Free
FOR PROFESSIONAL USE ONLY
Each 1 mL for oral administration
contains:
Cofaid-DC (Chlorpheniramine) Maleate
2 mg
Phenylephrine HCl
5 mg
APPLESAUCE FLAVOR
Tamper evident by foil seal under cap.
Do not use if foil seal is broken or missing.
Manufactured for:
EDWARDS
Pharmaceuticals, Inc.
Ripley, MS 38663
2 fl. oz. (60 mL)
Dextromethorphan:
Pharmacological action
Cofaid-DC is an antitussive medication. Inhibiting the excitability of the cough center this medicine suppresses the cough of any origin. Cofaid-DC (Dextromethorphan) has not addiction effects and it has no analgesic and hypnotic action. Cofaid-DC (Dextromethorphan) starts to act after 10-30 minutes after oral administration, the duration of therapeutic action: 5-6 hours for adults and 6-9 hours for children. Cofaid-DC (Dextromethorphan) is an optical isomer of levomethorphan which is similar to morphine. Due to optical isomerism this drug has no opioid effects. Cofaid-DC (Dextromethorphan) used mainly for replacement of codeine as a cough suppressant. In addition to the cough suppressant this medication is used in medicine for diagnostic purposes and may be useful in various cases - from seizures to heroin addiction treatment, some chronic neurodegenerative diseases. These include amyotrophic lateral sclerosis (ALS) (Charcot's disease), disease of "mad cow and other prion diseases. Cofaid-DC (Dextromethorphan) has also been used for the treatment of mental retardation, Parkinson's disease, in the treatment of lung and other cancers and to prevent tissue rejection in transplantation because of the (poorly known) effects of sigma ligands on tumor cells and immune system.
Pharmacokinetics
After oral administration Cofaid-DC (Dextromethorphan) is completely absorbed from the gastrointestinal tract. Cmax of Cofaid-DC (Dextromethorphan) in plasma is reached after 2 h. This medication biotransformes in the liver. Up to 45% of this drug is excreted by kidneys and there was considerable individual variation in rates of excretion of individual metabolites.
Why is Cofaid-DC prescribed?
Dry cough of different etiology.
Dosage and administration
For adults and children over 12 years Cofaid-DC prescribed on 15 mg 4 times / day, children aged 6 years - 7.5 mg 4 times / day.
Cofaid-DC (Dextromethorphan) side effects, adverse reactions
Drowsiness, nausea, dizziness.
Cofaid-DC contraindications
Bronchial asthma, bronchitis, simultaneous reception of mucolytic.
Using during pregnancy and breastfeeding
During pregnancy and lactation (breastfeeding) Cofaid-DC (Dextromethorphan) prescribed with caution, only in cases where the expected therapeutic effect for the mother outweighs the potential risk to the fetus or child.
Special instructions
With carefully administered Cofaid-DC (Dextromethorphan) with impaired liver function.
Cofaid-DC drug interactions
MAO inhibitors (including furazolidone, procarbazine, selegiline) when administered simultaneous with Cofaid-DC (Dextromethorphan) may cause adrenergic crisis, collapse, coma, dizziness, agitation, increased blood pressure, hyperpyrexia, intracranial hemorrhage, lethargy, nausea, cramps, tremor. In combination with tricyclic antidepressants (amitriptyline, etc.) Cofaid-DC (Dextromethorphan) may appeal serotonin syndrome and possible subsequent death. Amiodarone, fluoxetine, quinidine, inhibiting system cytochrome P450, may increase the drug concentration in the blood. Tobacco smoke can lead to increased secretion of glands in the background of inhibition of cough reflex. Some inhibitors of CYP450 (such as quinidine) increase and extended effects of this medicine.
Cofaid-DC in case of emergency / overdose
Symptoms: excitement, dizziness, respiratory depression, impaired consciousness, decreased blood pressure, tachycardia, muscle hypertonicity, ataxia.
Treatment: mechanical ventilation, symptomatic agents.
Menthol:
Cofaid-DC (Menthol) is a covalent organic compound made synthetically or obtained from peppermint or other mint oils. It is a waxy, crystalline substance, clear or white in color, which is solid at room temperature and melts slightly above. The main form of Cofaid-DC (Menthol) occurring in nature is (-)-menthol, which is assigned the (1R,2S,5R) configuration. Cofaid-DC (Menthol) has local anesthetic and counterirritant qualities, and it is widely used to relieve minor throat irritation.
Indication: Used to treat occasional minor irritation, pain, sore mouth, and sore throat as well as cough associated with a cold or inhaled irritants.
Cofaid-DC (Menthol) is a covalent organic compound made synthetically or obtained from peppermint or other mint oils. Menthol's ability to chemically trigger cold-sensitive receptors in the skin is responsible for the well known cooling sensation that it provokes when inhalated, eaten, or applied to the skin. It should be noted that Cofaid-DC (Menthol) does not cause an actual drop in temperature.
Phenylephrine:
- Drug facts
- Purpose
- Uses
- Warnings
- Directions
- Other information
- Inactive ingredients
- Questions? comments?
- Product packaging
Drug Facts
Active ingredients
(in each tablet)
Dexbrompheniramine Maleate 2 mg
Cofaid-DC (Phenylephrine) Hydrochloride 10 mg
Purpose
Antihistamine
Nasal Decongestant
Uses
Temporarily relieves these symptoms due to the common cold, hay fever (allergic rhinitis) or other upper respiratory allergies:
- runny nose
- sneezing
- itching of the nose or throat
- itchy, watery eyes
- nasal congestion
- reduces swelling of nasal passages
Warnings
Do not exceed recommended dosage.
Do not use this product
- if you are now taking a prescription monoamine oxidase inhibitor (certain drugs for depression, psychiatric, or emotional conditions, or Parkinson's disease), or for 2 weeks after stopping the MAOI drug. If you do not know if your prescription drug contains an MAOI, ask a doctor or pharmacist before taking this product.
Ask a doctor before use if you have
- a breathing problem such as emphysema or chronic bronchitis
- glaucoma
- trouble urinating due to enlargement of the prostate gland
- heart disease
- high blood pressure
- thyroid disease
- diabetes
Ask a doctor or pharmacist before use if you are taking sedatives or tranquilizers.
When using this product
- excitability may occur, especially in children
- may cause drowsiness
- avoid alcoholic drinks
- alcohol, sedatives, and tranquilizers may increase the drowsiness effect
- use caution when driving a motor vehicle or operating machinery
Stop use and ask a doctor if
- nervousness, dizziness, or sleeplessness occur
- symptoms do not improve within 7 days or are accompanied by fever
If pregnant or breast-feeding, ask a health professional before use.
Keep out of reach of children.
In case of overdose, get medical help or contact a Poison Control Center right away.
Directions
| Adults and children 12 years of age and over: | 1 tablet every 4 to 6 hours, not to exceed 6 tablets in 24 hours |
| Children 6 to under 12 years of age: | 1/2 tablet every 4 to 6 hours, not to exceed 3 tablets in 24 hours |
| Children under 6 years of age: | Consult a doctor |
Other information
Store at 15° - 30°C (59° - 86°F). Supplied in a tight, light-resistant container with a child-resistant cap. Cofaid-DC (Phenylephrine) Tablets are dark purple, caplet-shaped, scored tablets, debossed "Poly" bisect "782" on one side and plain on the other.
Inactive ingredients
colloidal silicon dioxide, croscarmellose sodium, D&C Red #27 aluminum lake, dibasic calcium phosphate dihydrate, FD &C Blue #1 aluminum lake, magnesium stearate, and silicified microcrystalline cellulose.
Questions? Comments?
Call1-800-882-1041
Manufactured for:
Poly Pharmaceuticals
Quitman, MS 39355 Rev. 02/12
Product Packaging
The packaging below represents the labeling currently used.
Principal display panel and side panel for 60 tablets label:
NDC 50991-782-60
Cofaid-DC (Phenylephrine)
Tablets
Antihistamine - Nasal Decongestant
Each tablet contains:
Dexbrompheniramine Maleate...2 mg
Cofaid-DC (Phenylephrine) Hydrochloride...10 mg
60 Tablets
Usual
Dosage: See product foldout for full prescribing information.
Tamper evident by foil seal under cap. Do not use if foil seal is
broken or missing.
KEEP THIS AND ALL DRUGS OUT OF REACH OF CHILDREN.
Store at controlled room temperature between 15°-30°C (59°-86°F).
Manufactured for:
Poly Pharmaceuticals
Quitman, MS 39355
Rev. 02/12
Cofaid-DC (Phenylephrine) Tablets Packaging Cofaid-DC (Phenylephrine) Tablets Packaging
Cofaid-DC pharmaceutical active ingredients containing related brand and generic drugs:
Cofaid-DC available forms, composition, doses:
Composition is the list of ingredients which combinedly form a medicine. Both active ingredients and inactive ingredients form the composition. The active ingredient gives the desired therapeutic effect whereas the inactive ingredient helps in making the medicine stable.
Doses are various strengths of the medicine like 10mg, 20mg, 30mg and so on. Each medicine comes in various doses which is decided by the manufacturer, that is, pharmaceutical company. The dose is decided on the severity of the symptom or disease.