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DRUGS & SUPPLEMENTS
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Indication: For the local treatment of oropharyngeal candidiasis and vaginal yeast infections, also used in fungal infections of the skin such as ringworm, athlete's foot, and jock itch.
Clotrimazole, an imidazole derivative with a broad spectrum of antimycotic activity, inhibits biosynthesis of the sterol ergostol, an important component of fungal cell membranes. Its action leads to increased membrane permeability and apparent disruption of enzyme systems bound to the membrane. Betamethasone and Clotrimazole are used together to treat cutaneous tinea infections. In studies in fungal cultures, the minimum fungicidal concentration of Clotrimazole caused leakage of intracellular phosphorous compounds into the ambient medium with concomitant breakdown of cellular nucleic acids, and accelerated potassium etflux. Both of these events began rapidly and extensively after addition of the drug to the cultures. The primary action of Clotrimazole is against dividing and growing organisms.
Clotrimazole is an antifungal agent of imidazole derivatives group for topical use. This medication has an effect at the expense of the synthesis of ergosterol, which is part of the cell membrane of fungi. Clotrimazole has a broad spectrum of action.
Clotrimazole is active against dermatophytes, molds, fungi of the genus Candida, Malassezia furfur.
This drug is also active against Corynebacterium minutissimum, Streptococcus spp., Staphylococcus spp., Trichomonas vaginalis.
For external use Clotrimazole is well into the various layers of the skin reaching therapeutic concentrations. When this medication applied topically a small amount of it absorbed into the bloodstream.
Fungal skin and mucous membranes: ringworm, tinea, trichophytosis, athlete, mikrosporiya, candidiasis, a fungal interdigital erosion, fungal paronychia; fungal infections complicated by a secondary pyoderma; colorful lichen, erythrasma; thrush; Candida vulvitis, vulvovaginitis, balanitis, trichomoniasis; for the renovation of the birth canal before delivery.
When Clotrimazole used externally it applied to affected skin 2-3 times / day in 2-4 weeks.
For local orally this medicine used 1-2 times / day, no more than 7 days.
Intravaginal - on 100-500 mg for 1-6 days.
Local reactions: contact allergic dermatitis, redness, burning sensation.
When applied topically to the skin: erythema, blisters, swelling, burning and tingling, irritation and flaking skin.
When applied topically for the treatment of urogenital infections: itching, burning, redness and swelling of the mucous membrane, vaginal discharge, frequent urination, intercurrent cystitis, burning sensation in the penis with a partner, pain during sexual intercourse.
When applied topically in the oral cavity: redness of the oral mucosa, burning sensation and tingling at the site of application, irritation.
Hypersensitivity to Clotrimazole, I trimester of pregnancy.
In experimental studies there have been found that Clotrimazole used in high doses exerts embryotoxic effect.
It is not known whether Clotrimazole released in breast milk. Although Clotrimazole is not contraindicated during pregnancy and lactation, it should be considered a potential risk when selecting antifungal therapy.
Prescribed intravaginal Dosage forms of Clotrimazole is not used during menstruation.
To prevent reinfection it should be simultaneous treatment of sexual partners.
Clotrimazole is not recommended for use in ophthalmology.
Simultaneous administration of Clotrimazole with amphotericin B, nystatin, natamycin activity of Clotrimazole decreases.
Symptoms: anorexia, nausea, vomiting, stomachodynia, abnormal liver function, rarely - drowsiness, hallucinations, thamuria, allergic skin reactions.
Treatment: taking activated charcoal, symptomatic therapy.
Price | |
Antifungal 1% cream | 0.27 USD |
CVS Pharmacy clotrimazole 1% cream | 0.32 USD |
Clotrim 1% vaginal cream | 0.18 USD |
Clotrimazole 1% Cream 15 gm Tube | 17.99 USD |
Clotrimazole 1% Cream 30 gm Tube | 35.99 USD |
Clotrimazole 1% Cream 45 gm Tube | 49.99 USD |
Clotrimazole 1% Solution 10ml Bottle | 17.99 USD |
Clotrimazole 1% Solution 30ml Bottle | 24.99 USD |
Clotrimazole 1% cream | 0.53 USD |
Clotrimazole 10 mg troche | 1.61 USD |
Clotrimazole 3 2% cream | 0.5 USD |
Clotrimazole 70 10 mg Troche Bottle | 117.04 USD |
Clotrimazole insert | 0.86 USD |
Clotrimazole powder | 5.2 USD |
Cream; Topical; Clotrimazole 1% | |
Cream; Topical; Clotrimazole 2% | |
Cream; Topical; Vaginal; Clotrimazole 1% | |
Cream; Vaginal; Clotrimazole 1% | |
Desenex 1% cream | 0.33 USD |
Gyne-lotrimin insert | 1.03 USD |
Lotrimin 1% cream | 1.28 USD |
Lotrimin af 2% liquid spray | 0.04 USD |
Lotrimin af 2% spray powder | 0.05 USD |
Lotrimin ultra 1% cream | 0.68 USD |
Mycelex 1% cream | 0.9 USD |
Mycelex 10 mg troche | 1.85 USD |
Mycelex-7 100 mg vaginal tablet | 1.33 USD |
Ointment; Topical; Clotrimazole 1% | |
Ra athlete's 1% foot cream | 0.37 USD |
Ra clotrimazole 3 cream | 0.46 USD |
Ra clotrimazole af cream | 0.24 USD |
Sm antifungal 1% cream | 0.25 USD |
Solution; Topical; Clotrimazole 1% | |
Tablets; Vaginal; Clotrimazole 100 mg | |
Tablets; Vaginal; Clotrimazole 200 mg | |
Tablets; Vaginal; Clotrimazole 500 mg | |
Troche / Lozenges; Oral; Clotrimazole 10 mg |
Depending on the reaction of the Clotrimazole after taken, if you are feeling dizziness, drowsiness or any weakness as a reaction on your body, Then consider Clotrimazole not safe to drive or operate heavy machine after consumption. Meaning that, do not drive or operate heavy duty machines after taking the capsule if the capsule has a strange reaction on your body like dizziness, drowsiness. As prescribed by a pharmacist, it is dangerous to take alcohol while taking medicines as it exposed patients to drowsiness and health risk. Please take note of such effect most especially when taking Primosa capsule. It's advisable to consult your doctor on time for a proper recommendation and medical consultations.
Is Clotrimazole addictive or habit forming?Medicines are not designed with the mind of creating an addiction or abuse on the health of the users. Addictive Medicine is categorically called Controlled substances by the government. For instance, Schedule H or X in India and schedule II-V in the US are controlled substances.
Please consult the medicine instruction manual on how to use and ensure it is not a controlled substance.In conclusion, self medication is a killer to your health. Consult your doctor for a proper prescription, recommendation, and guidiance.
Visitors | % | ||
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Twice in a day | 1 | 100.0% |
Visitors | % | ||
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1-5mg | 2 | 40.0% | |
6-10mg | 2 | 40.0% | |
201-500mg | 1 | 20.0% |
Visitors | % | ||
---|---|---|---|
1 week | 1 | 50.0% | |
2 days | 1 | 50.0% |
Visitors | % | ||
---|---|---|---|
46-60 | 2 | 50.0% | |
16-29 | 1 | 25.0% | |
> 60 | 1 | 25.0% |
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The information was verified by Dr. Rachana Salvi, MD Pharmacology