Cefocef-XL

Cefixime:

• Cefocef-XL information
• Cefocef-XL indications
• Cefocef-XL warnings
• Cefocef-XL intake guidelines
• Cefocef-XL dosage
• Cefocef-XL overdose
• Cefocef-XL Missed Dose
• Cefocef-XL side effects
• Cefocef-XL drug reactions
• Cefocef-XL (Cefixime) reviews

Cefocef-XL information

Cefocef-XL (Cefixime) is a semi-synthetic cephalosporin antibiotic, destined for oral use, which is able to reduce the development of the drug resistant bacteria.

Cefocef-XL indications

Cefocef-XL (Cefixime) is usually prescribed by doctors and personal health care providers to patients who are suffering from bacterial infections of the ears, throat, chest, urinary tract and to the individuals who have been diagnosed with the presence of a mild form of gonorrhea.

Cefocef-XL (Cefixime) may also be recommended in the treatment of other medical conditions, but only if the personal health care provider, pharmacist or doctor recommends it.

Cefocef-XL warnings

Patients should inform their doctor if they have had allergies to penicillin and cephalosporin antibiotics, if they have stomach and intestinal diseases (such as colitis). If the patients see no amelioration of the symptoms after a few days of treatment they should announce their caregiver. Patients who are experiencing vomiting, nausea and severe diarrhea during the treatment with Cefocef-XL (Cefixime) should talk with their doctor before taking anti-diarrheal drugs, because some of these medical products (like Lomotil or Paregoric) may worsen these symptoms.

The intake of Cefocef-XL (Cefixime) is known to cause false urine-sugar test results in the case of the diabetic patients. These patients should tell their doctor that they are taking Cefocef-XL (Cefixime), before they submit an urine sample. Individuals who are suffering from any kidney disorder should discuss with their doctor before beginning the treatment with this medicine, because they usually need dose adjustments in order for this drug not to interfere with their medical condition.

Women who are pregnant or are planning to become pregnant should discuss this matter with their personal health care provider or doctor, before beginning the treatment with Cefocef-XL (Cefixime), as this medicine may harm the baby.

Cefocef-XL intake guidelines

Patients are recommended to ask their doctor how to take every dose of Cefocef-XL (Cefixime) in order to obtain the best results during and after the treatment. Patients should pay attention to the doctor's recommendations and under no circumstances should they deviate from them. In the cases in which the patients have more questions about their treatment they should ask their doctor or pharmacist for further information.

As we said before, the dose of this drug must be adjusted for patients who are suffering from renal impairment, for individuals who are undergoing ambulatory peritoneal dialysis and hemodialysis.

This medicine can be taken in without food, but the patients who develop an upset stomach are recommended to take it with food, even if food slows down the rate of Zim's absorption. Patients, who are using a liquid from of this medicine, are recommended to use a measuring spoon, in order to be able to accurately measure their dose of Cefocef-XL (Cefixime).

Cefocef-XL dosage

The individuals will be prescribed by their personal health care provider the exact dose of Cefocef-XL (Cefixime) that they should use daily. Patients should not ignore the doctor's recommendations. Adult patients who are suffering from urethral gonococcal infections and uncomplicated cervical infections are usually recommended 400 mg per day. Children are recommended to take 8 mg per kilogram daily. This quantity may be taken as a single dose or divided in two doses which are to be taken every 12 hours.

Children who are known to weigh more than 50 kilograms and children who are older than 12 years are usually prescribed by their personal health care provider the adult dose of this medication, which consists in 400mg of drug which should be ingested daily.

As the functions of the kidneys usually decrease with age and as this medicine is eliminated from the organism by the kidneys, the personal health care provider will prescribe the elderly people only a small dose of Cefocef-XL (Cefixime).

Cefocef-XL overdose

Patients who believe that they have taken an overdose of Cefocef-XL (Cefixime) should immediately announce their doctor. Your personal physician will ask you to remain in the hospital for further tests and symptomatic treatment.

It is well known that any drug which is taken in excess can lead to a series of symptoms. In the case of a Cefocef-XL (Cefixime) overdose, the symptoms which a patient can experience include the following: nausea, diarrhea, vomiting, headaches, blood in the urine and upper abdominal pain.

Cefocef-XL Missed Dose

Patients are recommended to try to respect the schedule which their doctor gave them and not to skip any dose of Cefocef-XL (Cefixime). Individuals, who are supposed to take this medicine once a day and forget to take one of the doses, should take it as soon as they remember; then, they must wait 12 hours before the next dose. After taking the second dose of this product, the patients can return to their normal schedule.

Patients, who are taking Cefocef-XL (Cefixime) twice a day and forget to take one of the doses, should take it as soon as they recall and wait at least 6 hours before taking the next dose. After taking the second dose, they can proceed with their normal schedule.

Patients who are taking Cefocef-XL (Cefixime) three times a day and forget to take one or more of their scheduled doses, can take a dose of this remedy as soon as they remember, and wait at least 4 hours before taking the next dose; after this they can return to their regular schedule.

Cefocef-XL side effects

It is a well known the fact that any medicine has its side effects; in the case of Cefocef-XL (Cefixime), the clinical manifestations which can appear include: abdominal pain, gas, indigestion, loose stools, nausea, vomiting and mild diarrhea, headaches, itching, fever, dizziness and inflammation of the large intestine.

Cefocef-XL drug reactions

Patients should inform their doctor before beginning their treatment if they are taking Tegretol (which is a seizure medication) or Coumadin (which is an anticlotting medication). Patients should also inform their doctor of all the prescription and non prescription medicines that they are taking, including vitamins and herbal products.

Cloxacillin:

• Caution:
• Description:
• Storage:
• Action:
• Indications:
• Dosage for dry cows:
• Directions for use:
• Precautions:
• Residue warnings:
• How supplied:
• Cefocef-XL (Cloxacillin) reviews

NADA 055-058, Approved by FDA

Caution:

Federal law restricts this drug to use by or on the order of a licensed veterinarian.

Description:

Cefocef-XL (Cloxacillin) (cloxacillin benzathine) for Intramammary Infusion into the Dry Cow is a product which provides bactericidal activity against gram-positive bacteria. The active agent, Cefocef-XL (Cloxacillin) benzathine, is a sparingly soluble salt of the semisynthetic penicillin, Cefocef-XL (Cloxacillin). Cefocef-XL (Cloxacillin) is a derivative of 6-aminopenicillanic acid, and therefore is chemically related to other penicillins. It has, however, the antibacterial properties described below, which distinguish it from certain other penicillins.

Each 10 mL disposable syringe contains Cefocef-XL (Cloxacillin) benzathine equivalent to 500 mg of Cefocef-XL (Cloxacillin) activity in a stable peanut oil gel. This product was manufactured by a non-sterilizing process.

Storage:

Do not store above 25°C (77°F). Do not freeze.

Action:

In the non-lactating mammary gland, Cefocef-XL (Cloxacillin) (cloxacillin benzathine) provides bactericidal levels of the active antibiotic, Cefocef-XL (Cloxacillin), for a prolonged period of time. This prolonged activity is due to the low solubility of the Cefocef-XL (Cloxacillin) benzathine and to the slow-release oil-gel base. This prolonged contact between the antibiotic and the pathogenic organism enhances the probability of a bacteriological cure.

Cefocef-XL (Cloxacillin) is not destroyed by the enzyme, penicillinase, and therefore, is active against penicillin-resistant strains of Staphylococcus aureus. It is also active against non-penicillinase-producing Staphylococcus aureus as well as Streptococcus agalactiae.

The class disc, Methicillin 5 mcg, should be used to estimate the in vitro susceptibility of bacteria to Cefocef-XL (Cloxacillin).

Indications:

For the treatment of mastitis in dairy cows during the dry period.

Cefocef-XL (Cloxacillin) has been shown by extensive clinical studies to be efficacious in the treatment of mastitis in dry cows, when caused by Streptococcus agalactiae and Staphylococcus aureus including penicillin-resistant strains.

Treatment of the dry cow with Cefocef-XL (Cloxacillin) is indicated in any cow known to harbor any of these organisms in the udder at drying off, or which has had repeated attacks of mastitis during the previous lactation, or is affected with mastitis at drying off, if caused by susceptible organisms.

Dosage for Dry Cows:

Infuse the contents of one syringe (10 mL) into each quarter following the last milking. See Directions for Use.

Directions for Use:

Cefocef-XL (Cloxacillin) (cloxacillin benzathine) is for use in dry cows only. Administer immediately after the last milking. Use no later than 30 days prior to calving.

Completely milk out all four quarters. The udder and teats should be thoroughly washed with warm water containing a suitable dairy antiseptic and dried, preferably using individual paper towels. Carefully scrub the teat end and orifice with 70% alcohol, using a separate swab for each teat. Allow to dry.

Cefocef-XL (Cloxacillin) is packaged with the Opti-Sert^® Protective Cap.

For partial insertion: Twist off upper portion of the Opti-Sert Protective Cap to expose 3–4 mm of the syringe tip.

For full insertion: Remove protective cap to expose the full length of the syringe tip.

Insert syringe tip into the teat canal and expel the entire contents of syringe into the quarter. Withdraw the syringe and gently massage the quarter to distribute the medication.

Do not infuse contents of the mastitis syringe into the teat canal if the Opti-Sert Protective Cap is broken or damaged.

Precautions:

Because it is a derivative of 6-aminopenicillanic acid, Cefocef-XL (Cloxacillin) has the potential for producing allergic reactions. Such reactions are rare; however, should they occur, the subject should be treated with antihistamines or pressor amines, such as epinephrine.

Residue Warnings:

1. For use in dry cows only.

2. Not to be used within 30 days of calving.

3. Any animal infused with this product must not be slaughtered for food until 30 days after the latest infusion.

How Supplied:

Cefocef-XL (Cloxacillin) (cloxacillin benzathine) Intramammary Infusion is supplied as 10 mL syringes containing 500 mg of Cefocef-XL (Cloxacillin) activity per syringe. One display carton contains 12 syringes. One pail contains 144 syringes.

NDC 0010-4720-01 - 10 mL syringe

NDC 0010-4720-02 - 12 syringes

NDC 0010-4720-03 - 144 syringes

Opti-Sert is a registered trademark of Zoetis W LLC - used under license.

Cefocef-XL (Cloxacillin) is a registered trademark of Boehringer Ingelheim Vetmedica, Inc.

© 2014 Boehringer Ingelheim Vetmedica, Inc. All Rights Reserved.

Made in Italy

Manufactured for:

Boehringer Ingelheim Vetmedica, Inc.

St. Joseph, MO 64506 U.S.A.

51729292

472001-03