DRUGS & SUPPLEMENTS

Azyxin

Name: Azyxin drug & pharmaceuticals. Azyxin available forms, doses, prices
Creator: sdrugs.com
Published: 2021-11-11T10:10:10+00:00

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Azyxin uses

Pharmacological action
Pharmacokinetics
Why is Azyxin prescribed?
Dosage and administration
Azyxin side effects, adverse reactions
Contraindications
Using during pregnancy and breastfeeding
Special instructions
Azyxin drug interactions
Azyxin reviews

Pharmacological action

Azyxin is a macrolide antibiotic of azalides group. Azyxin inhibits RNA-dependent protein synthesis of sensitive microorganisms.

It active against gram-positive bacteria: Staphylococcus aureus, Streptococcus spp. ; gram-negative bacteria: Haemophilus influenzae, Haemophilus parainfluenzae, Haemophilus ducreyi, Moraxella catarrhalis, Escherichia coli, Bordetella pertussis, Bordetella parapertussis, Borrelia burgdorferi, Neisseria gonorrhoeae, Campylobacter spp., Legionella pneumophila; anaerobic bacteria: Bacteroides fragilis.

Pharmacokinetics

Azyxin rapidly absorbed from the gastrointestinal tract. Ingestion reduces the absorption of Azyxin. C_max in plasma is reached after 2-3 hours. This medicine rapidly distributed in tissues and biological fluids. 35% of the Azyxin is metabolized in the liver by demethylation. More than 59% is excreted in the bile in unchanged form, about 4.5% in the urine in unchanged form.

Why is Azyxin prescribed?

Infectious-inflammatory diseases caused by microorganisms susceptible to Azyxin, including bronchitis, pneumonia, infections of skin and soft tissue, otitis media, sinusitis, pharyngitis, tonsillitis, gonorrheal and non gonorrheal urethritis and / or cervicitis, Lyme disease.

Dosage and administration

Dosage of Azyxin is setted individually according to nosology, disease severity and sensitivity of the pathogen. Dosage for adults for oral administration is 0.25-1 g 1 time/day; for children - 5-10 mg/kg 1 time/day. The duration of administration is 2-5 days.

Azyxin side effects, adverse reactions

Digestive system: nausea, vomiting, flatulence, diarrhea, abdominal pain, transient elevation of liver enzymes, rarely - cholestatic jaundice.

Allergic reactions: rarely - a skin rash, angioedema, erythema multiforme, Stevens-Johnson syndrome, toxic epidermal necrolysis.

Dermatological reactions: rarely - photosensitization.

CNS: dizziness, headache, rarely - drowsiness, weakness.

Hematopoietic system: rarely - leukopenia, neutropenia, thrombocytopenia.

Cardiovascular system: rarely - chest pain.

Urogenital system: vaginitis, rarely - candidiasis, nephritis, increased residual nitrogen urea.

Other: rarely - hyperglycemia, arthralgia.

Contraindications

Hypersensitivity to Azyxin and other macrolide antibiotics.

Using during pregnancy and breastfeeding

Azyxin crosses the placental barrier. Use in pregnancy only in cases where the intended benefits to the mother outweighs the potential risk to the fetus.

If necessary to use Azyxin in the lactation period should solve the issue of termination of breastfeeding.

Special instructions

Azyxin not recommended for use in patients with compromised liver function.

Azyxin uses with careful with impaired renal function.

This medication should be taken at least 1 hour before or 2 hours after eating or taking of antacids.

Azyxin drug interactions

Simultaneous administration of Azyxin with these drugs and medications may has followed effects:

ergot alkaloids: can not been exclude the risk of ergotism;

warfarin: there was described amplification effect of warfarin;

digoxin or digitoxin: may be significantly increase the concentration of cardiac glycosides in plasma and risk of glycoside intoxication;

disopyramide: described a case of ventricular fibrillation;

lovastatin: there was describes some cases of rhabdomyolysis;

Azyxin with rifabutin increases risk of neutropenia and leukopenia;

cyclosporine: disturbed metabolism of cyclosporine which increases the risk of adverse and toxic reactions caused by cyclosporine

Azyxin pharmaceutical active ingredients containing related brand and generic drugs:

Azithromycin

Azyxin available forms, composition, doses:

Tablets; Oral; Azithromycin 250 mg
Tablets; Oral; Azithromycin 500 mg

Azyxin destination | category:

Human:
Macrolide antibiotics

Azyxin Anatomical Therapeutic Chemical codes:

J01FA10 - Azithromycin

Azyxin pharmaceutical companies:

Centaur Pharmaceuticals

References

Dailymed."AZITHROMYCIN TABLET, FILM COATED [PHYSICIANS TOTAL CARE, INC.]". https://dailymed.nlm.nih.gov/dailym... (accessed August 28, 2018).
Dailymed."AZITHROMYCIN: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailym... (accessed August 28, 2018).
"azithromycin". https://pubchem.ncbi.nlm.nih.gov/co... (accessed August 28, 2018).

Frequently asked Questions

Can i drive or operate heavy machine after consuming Azyxin?

Depending on the reaction of the Azyxin after taken, if you are feeling dizziness, drowsiness or any weakness as a reaction on your body, Then consider Azyxin not safe to drive or operate heavy machine after consumption. Meaning that, do not drive or operate heavy duty machines after taking the capsule if the capsule has a strange reaction on your body like dizziness, drowsiness. As prescribed by a pharmacist, it is dangerous to take alcohol while taking medicines as it exposed patients to drowsiness and health risk. Please take note of such effect most especially when taking Primosa capsule. It's advisable to consult your doctor on time for a proper recommendation and medical consultations.

Is Azyxin addictive or habit forming?

Medicines are not designed with the mind of creating an addiction or abuse on the health of the users. Addictive Medicine is categorically called Controlled substances by the government. For instance, Schedule H or X in India and schedule II-V in the US are controlled substances.

Please consult the medicine instruction manual on how to use and ensure it is not a controlled substance.In conclusion, self medication is a killer to your health. Consult your doctor for a proper prescription, recommendation, and guidiance.

Review

sdrugs.com conducted a study on Azyxin, and the result of the survey is set out below. It is noteworthy that the product of the survey is based on the perception and impressions of the visitors of the website as well as the views of Azyxin consumers. We, as a result of this, advice that you do not base your therapeutic or medical decisions on this result, but rather consult your certified medical experts for their recommendations.