Azitrox

Rating: 1.65 - 3 review(s)
What are the side effects you encounter while taking this medicine?
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Azitrox uses


Pharmacological action

Azitrox is a macrolide antibiotic of azalides group. Azitrox inhibits RNA-dependent protein synthesis of sensitive microorganisms.

It active against gram-positive bacteria: Staphylococcus aureus, Streptococcus spp. ; gram-negative bacteria: Haemophilus influenzae, Haemophilus parainfluenzae, Haemophilus ducreyi, Moraxella catarrhalis, Escherichia coli, Bordetella pertussis, Bordetella parapertussis, Borrelia burgdorferi, Neisseria gonorrhoeae, Campylobacter spp., Legionella pneumophila; anaerobic bacteria: Bacteroides fragilis.

Pharmacokinetics

Azitrox rapidly absorbed from the gastrointestinal tract. Ingestion reduces the absorption of Azitrox. Cmax in plasma is reached after 2-3 hours. This medicine rapidly distributed in tissues and biological fluids. 35% of the Azitrox is metabolized in the liver by demethylation. More than 59% is excreted in the bile in unchanged form, about 4.5% in the urine in unchanged form.

Why is Azitrox prescribed?

Infectious-inflammatory diseases caused by microorganisms susceptible to Azitrox, including bronchitis, pneumonia, infections of skin and soft tissue, otitis media, sinusitis, pharyngitis, tonsillitis, gonorrheal and non gonorrheal urethritis and / or cervicitis, Lyme disease.

Dosage and administration

Dosage of Azitrox is setted individually according to nosology, disease severity and sensitivity of the pathogen. Dosage for adults for oral administration is 0.25-1 g 1 time/day; for children - 5-10 mg/kg 1 time/day. The duration of administration is 2-5 days.

Azitrox side effects, adverse reactions

Digestive system: nausea, vomiting, flatulence, diarrhea, abdominal pain, transient elevation of liver enzymes, rarely - cholestatic jaundice.

Allergic reactions: rarely - a skin rash, angioedema, erythema multiforme, Stevens-Johnson syndrome, toxic epidermal necrolysis.

Dermatological reactions: rarely - photosensitization.

CNS: dizziness, headache, rarely - drowsiness, weakness.

Hematopoietic system: rarely - leukopenia, neutropenia, thrombocytopenia.

Cardiovascular system: rarely - chest pain.

Urogenital system: vaginitis, rarely - candidiasis, nephritis, increased residual nitrogen urea.

Other: rarely - hyperglycemia, arthralgia.

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Contraindications

Hypersensitivity to Azitrox and other macrolide antibiotics.

Using during pregnancy and breastfeeding

Azitrox crosses the placental barrier. Use in pregnancy only in cases where the intended benefits to the mother outweighs the potential risk to the fetus.

If necessary to use Azitrox in the lactation period should solve the issue of termination of breastfeeding.

Special instructions

Azitrox not recommended for use in patients with compromised liver function.

Azitrox uses with careful with impaired renal function.

This medication should be taken at least 1 hour before or 2 hours after eating or taking of antacids.

Azitrox drug interactions

Simultaneous administration of Azitrox with these drugs and medications may has followed effects:

  • ergot alkaloids: can not been exclude the risk of ergotism;
  • warfarin: there was described amplification effect of warfarin;
  • digoxin or digitoxin: may be significantly increase the concentration of cardiac glycosides in plasma and risk of glycoside intoxication;
  • disopyramide: described a case of ventricular fibrillation;
  • lovastatin: there was describes some cases of rhabdomyolysis;
  • Azitrox with rifabutin increases risk of neutropenia and leukopenia;
  • cyclosporine: disturbed metabolism of cyclosporine which increases the risk of adverse and toxic reactions caused by cyclosporine

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    Azitrox pharmaceutical active ingredients containing related brand and generic drugs:


    Azitrox available forms, composition, doses:


    Azitrox destination | category:


    Azitrox Anatomical Therapeutic Chemical codes:


    Azitrox pharmaceutical companies:


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    References

    1. Dailymed."AZITHROMYCIN TABLET, FILM COATED [PHYSICIANS TOTAL CARE, INC.]". https://dailymed.nlm.nih.gov/dailym... (accessed August 28, 2018).
    2. Dailymed."AZITHROMYCIN: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailym... (accessed August 28, 2018).
    3. "azithromycin". https://pubchem.ncbi.nlm.nih.gov/co... (accessed August 28, 2018).

    Frequently asked Questions

    Can i drive or operate heavy machine after consuming Azitrox?

    Depending on the reaction of the Azitrox after taken, if you are feeling dizziness, drowsiness or any weakness as a reaction on your body, Then consider Azitrox not safe to drive or operate heavy machine after consumption. Meaning that, do not drive or operate heavy duty machines after taking the capsule if the capsule has a strange reaction on your body like dizziness, drowsiness. As prescribed by a pharmacist, it is dangerous to take alcohol while taking medicines as it exposed patients to drowsiness and health risk. Please take note of such effect most especially when taking Primosa capsule. It's advisable to consult your doctor on time for a proper recommendation and medical consultations.

    Is Azitrox addictive or habit forming?

    Medicines are not designed with the mind of creating an addiction or abuse on the health of the users. Addictive Medicine is categorically called Controlled substances by the government. For instance, Schedule H or X in India and schedule II-V in the US are controlled substances.

    Please consult the medicine instruction manual on how to use and ensure it is not a controlled substance.In conclusion, self medication is a killer to your health. Consult your doctor for a proper prescription, recommendation, and guidiance.

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    Review

    sdrugs.com conducted a study on Azitrox, and the result of the survey is set out below. It is noteworthy that the product of the survey is based on the perception and impressions of the visitors of the website as well as the views of Azitrox consumers. We, as a result of this, advice that you do not base your therapeutic or medical decisions on this result, but rather consult your certified medical experts for their recommendations.

    Visitor reports

    Visitor reported useful

    No survey data has been collected yet

    Three visitors reported side effects

    Did you get side effects while taking the Azitrox drug, or were there no side effects?
    According to the survey conducted by website sdrugs.com users, the below-mentioned percentages indicate the number of people experiencing the side effects and the number of people not experiencing the side effects when taking Azitrox medicine. Every drug produces minimal side effects, and they are negligible most times, when compared to the desired effect [use] of the medicine. Side effects depend on the dose you are taking, any drug interactions that happen when you are on other medications, if the patient is sensitive, and other associated conditions. If you cannot tolerate the side effects, consult your doctor immediately, so he can either adjust the dose or change the medication.
    Visitors%
    It has side effects2
    66.7%
    No side effects1
    33.3%

    Visitor reported price estimates

    No survey data has been collected yet

    Two visitors reported frequency of use

    How often in a day do you take the medicine?
    Are you taking the Azitrox drug as prescribed by the doctor?

    Few medications can be taken Once in a day more than prescribed when the doctor's advice mentions the medicine can be taken according to frequency or severity of symptoms. Most times, be very careful and clear about the number of times you are taking the medication. The report of sdrugs.com website users about the frequency of taking the drug Azitrox is mentioned below.
    Visitors%
    Once in a day2
    100.0%

    Five visitors reported doses

    What is the dose of Azitrox drug you are taking?
    According to the survey conducted among sdrugs.com website users, the maximum number of people are using the following dose 201-500mg. Few medications come in only one or two doses. Few are specific for adult dose and child dose. The dose of the medicine given to the patient depends on the severity of the symptom/disease. There can be dose adjustments made by the doctor, based on the progression of the disease. Follow-up is important.
    Visitors%
    201-500mg4
    80.0%
    501mg-1g1
    20.0%

    One visitor reported time for results

    What is the time duration Azitrox drug must be taken for it to be effective or for it to reduce the symptoms?
    Most chronic conditions need at least some time so the dose and the drug action gets adjusted to the body to get the desired effect. The stastistics say sdrugs.com website users needed 3 days to notice the result from using Azitrox drug. The time needed to show improvement in health condition after using the medicine Azitrox need not be same for all the users. It varies based on other factors.
    Visitors%
    3 days1
    100.0%

    Three visitors reported administration

    The drugs are administered in various routes, like oral or injection form. They are administered before food or after food. How are you taking Azitrox drug, before food or after food?
    Click here to find out how other users of our website are taking it. For any doubts or queries on how and when the medicine is administered, contact your health care provider immediately.
    Visitors%
    Empty stomach1
    33.3%
    After food1
    33.3%
    Before food1
    33.3%

    Two visitors reported age

    Visitors%
    16-292
    100.0%

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    The information was verified by Dr. Rachana Salvi, MD Pharmacology

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