DRUGS & SUPPLEMENTS

Anxit Forte

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Anxit Forte uses

Anxit Forte consists of Alprazolam, Sertraline.

Alprazolam:


Pharmacological action

Anxit Forte is an anxiolytic drug (tranquilizer), a derivative of triazolo-benzodiazepine. This medication has anxiolytic, sedative, hypnotic, anticonvulsant, central muscle relaxant effect. The mechanism of action is to enhance the inhibitory effect of endogenous GABA in the CNS by increasing the sensitivity of the GABA-receptor mediator as a result of stimulation of benzodiazepine receptors located in the allosteric center of postsynaptic GABA-receptor activating ascending reticular formation of brain stem neurons and the lateral horns of the spinal cord; reduces the excitability of the subcortical brain structures (the limbic system, thalamus, hypothalamus), inhibits the polysynaptic spinal reflexes.

Pronounced anxiolytic activity (reduction of emotional tension, easing anxiety, fear, anxiety) is combined with moderate soporific effect; it shortens the period of sleep, increases sleep duration and reduces the number of nighttime awakenings. The mechanism of hypnotic action is inhibition of cell reticular formation of the brain.

Pharmacokinetics

After oral administration Anxit Forte (Alprazolam) is rapidly and completely absorbed from the gastrointestinal tract. Cmax plasma levels achieved within 1-2 hours. Binding to plasma proteins is 80%. This drud metabolized in the liver. T1/2 is an average of 12-15 hours. Anxit Forte (Alprazolam) and its metabolites are mainly excreted by kidneys.

Why is Anxit Forte prescribed?

  • anxiety, neurosis accompanied by anxiety, danger, stress, deterioration of sleep, irritability, and somatic disorders
  • mixed anxiety-depressive conditions
  • neurotic reactive depression accompanied by depressed mood, loss of interest in his surroundings, anxiety, loss of sleep, decreased appetite, and somatic disorders
  • anxiety and neurotic depression that developed on the background of systemic diseases
  • panic disorder in combination and without symptoms of phobias

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    Dosage and administration

    Individual. It is recommended to use the minimum effective dose of Anxit Forte. The dose is corrected in the treatment process depending on the achieved effect and tolerability. If necessary, increase the dose should be increased gradually, first in the evening and then in the daytime reception.

    The initial dose of Anxit Forte (Alprazolam) is 250-500 mg 3 times / day, if necessary, it gradually increases to 4.5 mg / day.

    For elderly or debilitated patients the initial dose is 250 mg 2-3 / day, maintenance doses - 500-750 mg / day, if necessary, taking into account the tolerance dose can be increased.

    Cancellation or reduction of the dose of Anxit Forte (Alprazolam) should be done gradually by reducing the daily dose of no more than 500 mcg every 3 days; sometimes can needed even more slowly cancelling.

    Anxit Forte (Alprazolam) side effects, adverse reactions

    CNS: at the beginning of treatment (especially in elderly patients) drowsiness, fatigue, dizziness, decreased ability to concentrate, ataxia, disorientation, unsteady gait, slowing of mental and motor responses; rare - headache, euphoria, depression, tremors, memory loss, impaired coordination of movements, depressed mood, confusion, extrapyramidal dystonic reactions (involuntary movements, including for eyes), weakness, myasthenia gravis, dysarthria; in some cases - paradoxical reactions (aggressive flare, confusion, psychomotor agitation, fear, suicidal tendencies, muscle spasms, hallucinations, agitation, irritability, anxiety, insomnia).

    Digestive system: possible dry mouth or excessive salivation, heartburn, nausea, vomiting, decreased appetite, constipation or diarrhea, abnormal liver function, elevated liver transaminases and alkaline phosphatase, jaundice.

    Hematopoietic system: possible leukopenia, neutropenia, agranulocytosis (chills, pyrexia, sore throat, extreme tiredness or weakness), anemia, thrombocytopenia.

    Urinary tract: possible urinary incontinence, urinary retention, renal failure, decreased or increased libido, dysmenorrhea.

    Endocrine system: possible change in body weight, disturbances in libido, menstrual irregularities.

    Cardiovascular system: possible decrease in blood pressure, tachycardia.

    Allergic reactions: possible skin rash, itching.

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    Contraindications

    Coma, shock, myasthenia gravis, angle-closure glaucoma, acute alcohol poisoning (with the weakening of the vital functions), narcotic analgesics, hypnotics and psychotropic drugs, chronic obstructive airways disease with incipient respiratory failure, acute respiratory failure, severe depression (suicidal tendencies may occur), pregnancy (especially the I trimester), lactation, childhood and adolescence to 18 years, increased sensitivity to benzodiazepines.

    Using during pregnancy and breastfeeding

    Anxit Forte (Alprazolam) has a toxic effect on the fetus and increases the risk of birth defects when used in the I trimester of pregnancy. The constant use during pregnancy can cause physical dependence with the development of withdrawal syndrome in the newborn. Reception at therapeutic doses in the later stages of pregnancy can cause neonatal CNS depression. Using of Anxit Forte (Alprazolam) immediately before birth or during labor can cause neonatal respiratory depression, decreased muscle tone, hypotension, hypothermia and a weak act of sucking (sucking flaccid syndrome baby).

    It is possible to excretion of the benzodiazepines in breast milk that can cause drowsiness in the newborn and hinder feeding.

    In experimental studies have been shown that Anxit Forte (Alprazolam) and its metabolites are excreted in breast milk.

    Special instructions

    Keep in mind that anxiety or conditions related to everyday stress usually does not require treatment with anxiolytics.

    If you experience paradoxical reactions then stop taking the drug. During the period of treatment is unacceptable to use of alcoholic drinks. With caution use Anxit Forte for drivers of vehicles and people whose profession is associated with increased concentration.

    Anxit Forte (Alprazolam) drug interactions

    The simultaneous use of Anxit Forte (Alprazolam) with psychotropic, anticonvulsant medications and ethanol is observed enhancement inhibitory action Anxit Forte (Alprazolam) on the CNS.

    The simultaneous use with blockers of histamine H2-receptor reduce the clearance of Anxit Forte (Alprazolam) and increase the inhibitory effect of Anxit Forte (Alprazolam) on the CNS; macrolide antibiotics reduce the clearance of Anxit Forte (Alprazolam).

    The simultaneous use with hormonal oral contraceptives increased T1/2 of Anxit Forte (Alprazolam).

    Simultaneous administration of Anxit Forte (Alprazolam) with dextropropoxyphene observed a more pronounced CNS depression than in combination with other benzodiazepines, as may increase the concentration of Anxit Forte (Alprazolam) in blood plasma.

    Simultaneous treatment with digoxin increases the risk of intoxication by cardiac glycosides.

    Anxit Forte (Alprazolam) increases the concentration of imipramine in plasma.

    Simultaneous administration with itraconazole, ketoconazole increases the effects of Anxit Forte (Alprazolam).

    Simultaneous administration with paroxetine may increases the effects of Anxit Forte (Alprazolam) due to the inhibition of its metabolism.

    Fluvoxamine increases the concentration of Anxit Forte (Alprazolam) in plasma and risk of its side effects.

    Simultaneous administration of Anxit Forte (Alprazolam) with fluoxetine may increase the concentration of Anxit Forte (Alprazolam) in plasma by decreasing its metabolism and clearance under the influence of fluoxetine which is accompanied by psychomotor disorders.

    It can not be exclude the possibility of strengthening effect of Anxit Forte (Alprazolam) for simultaneous administration with erythromycin.

    Anxit Forte in case of emergency / overdose

    Symptoms: Varying degrees of CNS oppression (from sleepiness to coma) - drowsiness, confusion; in more severe cases (especially in patients receiving other drugs depressing the central nervous system or alcohol) - ataxia, decreased reflexes, hypotension, coma.

    Treatment: induction of vomiting, gastric lavage, symptomatic therapy, monitor vital signs. In severe hypotension prescribed an injection of norepinephrine. Specific antidote is benzodiazepine receptor antagonist flumazenil (administration only in a hospital).

  • Sertraline:


    Pharmacological action

    Anxit Forte (with the generic name of Anxit Forte (Sertraline)) belongs to the groups of drugs known as selective serotonin reuptake inhibitors. These selective serotonin reuptake drugs influence chemical imbalance in the brain responsible for depression, panic anxiety, obsessive compulsive disorder and others.

    Why is Anxit Forte (Sertraline) prescribed?

    Anxit Forte (Sertraline) is indicated for the treatment of:

  • depression
  • panic
  • anxiety disorders
  • obsessive compulsive disorder
  • PSTD or post traumatic stress disorder
  • PMDD or premenstrual dysphoric disorder
  • social phobia

    This medication may also be used for other medical purposes not stated herein.

    Dosage and administration

    When you order Anxit Forte, it should be taken exactly as prescribed by your doctor. Each tablet must be taken with a full glass of water.

    For the oral concentrate of this medicine, it must be diluted before taking a dose. A dropper must adequately measure the amount of liquid to be diluted on the oral concentrate.

    Each dose of Anxit Forte (Sertraline) should be taken at around the same time each day.

    This drug can be taken with or without food.

    Anxit Forte (Sertraline) is usually taken once a day and at the same time of each day. For the complete and exact dosage, refer to your doctor as other factors may also be considered such as body weight, age and the degree of illness.

    When a dose of Anxit Forte (Sertraline) is missed, it is advisable to skip that dose and proceed to the next one. However, if the next dosage is many hours away, you could take the missed dose. It is not advisable to take the missed dose of this medication if you are near the time for the next dose, it is best if you entirely skip that dose and wait for the schedule of the next one.

    Anxit Forte (Sertraline) side effects

    The intake of Anxit Forte (Sertraline) depression medication may entail side effects depending on the susceptibility of the person. Some of the serious side effects tied to Anxit Forte (Sertraline) medication are:

  • allergic reaction such as hives, swelling of lips, closing of throat
  • irregular heartbeats
  • low blood pressure characterized by dizziness and weakness
  • high blood pressure accompanied by severe headache and blurred vision
  • chills and feverIf you experience any of the mentioned side effects, you must immediately stop your Anxit Forte (Sertraline) intake and consult your doctor.

    Other less serious side effects of this medication include:

  • headaches
  • tremors
  • nausea
  • diarrhea
  • dry mouth and throat
  • weight loss and decrease in appetite
  • decrease in sex drive or impotenceIf you have experienced any of the mentioned symptoms you should tell your doctor as your dosage may be lowered or you may be advised to stop taking this drug.

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    Contraindications

    Concomitant use in patients taking monoamine oxidase inhibitors is contraindicated. Concomitant use in patients taking pimozide is contraindicated.

    Anxit Forte (Sertraline) is contraindicated in patients with a hypersensitivity to Anxit Forte (Sertraline) or any of the inactive ingredients in this drug.

    Anxit Forte (Sertraline) oral concentrate is contraindicated with ANT ABUSE (disulfiram) due to the alcohol content of the concentrate.

    Using during pregnancy and breastfeeding

    Before you buy Anxit Forte (Sertraline) online, understand that it belongs to the Pregnancy Category X type of drugs, which means that it is harmful to the unborn child. Taking Anxit Forte (Sertraline), especially during the last trimester of pregnancy, may cause birth defects and other medical complications for the mother. The active ingredient Anxit Forte (Sertraline) has not been tested to see if it passes through breast milk. Before deciding to breastfeed you should first consult your doctor.

    Special instructions

    While on Anxit Forte anti-depression medication, mental conditions may worsen - especially at the start of treatment due to the initial introduction of the medicine to your nervous system.

    Expect the following conditions to worsen, especially at the first intake of Anxit Forte (Sertraline):

  • anxiety
  • panic attacks
  • insomnia
  • irritability
  • hostility
  • impulsivity
  • restlessness
  • mental or physical hyperactivity
  • suicidal thoughts and actionsNever take this drug without your doctor's approval and monitoring unpleasant side effects may plague you especially at the first intake of this medicine.

    Your general mental condition should be monitored before, during and after treatment of Anxit Forte (Sertraline) as some undesired effects may occur when on Anxit Forte (Sertraline) medication.

    Before taking Anxit Forte (Sertraline), you should first tell your doctor if you any of the following medical conditions as taking this medicine may worsen it:

  • liver problems
  • kidney malfunctions
  • suffering from seizures
  • have manic depressive thoughts or suicidal tendenciesIf you do suffer from any of the conditions mentioned you may be advised to forego Anxit Forte (Sertraline) treatment or your dosage may be significantly lowered.

    Anxit Forte (Sertraline) drug interactions

    Never take Anxit Forte (Sertraline) if you are taking:

  • monoamine oxidase inhibitor (MAOI)
  • pimozide - dangerous reactions could result
  • disulfiramTell your doctor if you are taking the following drugs:
  • benzodiazepine
  • tricyclic antidepressants
  • phenothiazine
  • lithium
  • almotriptan
  • carbamazepine
  • warfarin
  • digoxin
  • cimetidine
  • bupropionYou may be advised to lower your dosage or to entirely stop this medication.

    Anxit Forte in case of emergency / overdose

    When symptoms of overdose are suspected, seek medical attention immediately. The symptoms of overdose may be characterized by: nausea; vomiting; tremors; seizures; extreme drowsy feeling; hyperactivity; enlarged and dilated pupils.

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    Anxit Forte pharmaceutical active ingredients containing related brand and generic drugs:

    infoActive ingredient is the part of the drug or medicine which is biologically active. This portion of the drug is responsible for the main action of the drug which is intended to cure or reduce the symptom or disease. The other portions of the drug which are inactive are called excipients; there role is to act as vehicle or binder. In contrast to active ingredient, the inactive ingredient's role is not significant in the cure or treatment of the disease. There can be one or more active ingredients in a drug.


    Anxit Forte available forms, composition, doses:

    infoForm of the medicine is the form in which the medicine is marketed in the market, for example, a medicine X can be in the form of capsule or the form of chewable tablet or the form of tablet. Sometimes same medicine can be available as injection form. Each medicine cannot be in all forms but can be marketed in 1, 2, or 3 forms which the pharmaceutical company decided based on various background research results.
    Composition is the list of ingredients which combinedly form a medicine. Both active ingredients and inactive ingredients form the composition. The active ingredient gives the desired therapeutic effect whereas the inactive ingredient helps in making the medicine stable.
    Doses are various strengths of the medicine like 10mg, 20mg, 30mg and so on. Each medicine comes in various doses which is decided by the manufacturer, that is, pharmaceutical company. The dose is decided on the severity of the symptom or disease.


    Anxit Forte destination | category:

    infoDestination is defined as the organism to which the drug or medicine is targeted. For most of the drugs what we discuss, human is the drug destination.
    Drug category can be defined as major classification of the drug. For example, an antihistaminic or an antipyretic or anti anginal or pain killer, anti-inflammatory or so.


    Anxit Forte Anatomical Therapeutic Chemical codes:

    infoA medicine is classified depending on the organ or system it acts [Anatomical], based on what result it gives on what disease, symptom [Therapeutical], based on chemical composition [Chemical]. It is called as ATC code. The code is based on Active ingredients of the medicine. A medicine can have different codes as sometimes it acts on different organs for different indications. Same way, different brands with same active ingredients and same indications can have same ATC code.


    Anxit Forte pharmaceutical companies:

    infoPharmaceutical companies are drug manufacturing companies that help in complete development of the drug from the background research to formation, clinical trials, release of the drug into the market and marketing of the drug.
    Researchers are the persons who are responsible for the scientific research and is responsible for all the background clinical trials that resulted in the development of the drug.


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    References

    1. Dailymed."NIRAVAM (ALPRAZOLAM) TABLET, ORALLY DISINTEGRATING [STAT RX USA LLC]". https://dailymed.nlm.nih.gov/dailym... (accessed August 28, 2018).
    2. Dailymed."ALPRAZOLAM: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailym... (accessed August 28, 2018).
    3. "sertraline". https://pubchem.ncbi.nlm.nih.gov/co... (accessed August 28, 2018).

    Frequently asked Questions

    Can i drive or operate heavy machine after consuming Anxit Forte?

    Depending on the reaction of the Anxit Forte after taken, if you are feeling dizziness, drowsiness or any weakness as a reaction on your body, Then consider Anxit Forte not safe to drive or operate heavy machine after consumption. Meaning that, do not drive or operate heavy duty machines after taking the capsule if the capsule has a strange reaction on your body like dizziness, drowsiness. As prescribed by a pharmacist, it is dangerous to take alcohol while taking medicines as it exposed patients to drowsiness and health risk. Please take note of such effect most especially when taking Primosa capsule. It's advisable to consult your doctor on time for a proper recommendation and medical consultations.

    Is Anxit Forte addictive or habit forming?

    Medicines are not designed with the mind of creating an addiction or abuse on the health of the users. Addictive Medicine is categorically called Controlled substances by the government. For instance, Schedule H or X in India and schedule II-V in the US are controlled substances.

    Please consult the medicine instruction manual on how to use and ensure it is not a controlled substance.In conclusion, self medication is a killer to your health. Consult your doctor for a proper prescription, recommendation, and guidiance.

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    Review

    sDrugs.com conducted a study on Anxit Forte, and the result of the survey is set out below. It is noteworthy that the product of the survey is based on the perception and impressions of the visitors of the website as well as the views of Anxit Forte consumers. We, as a result of this, advice that you do not base your therapeutic or medical decisions on this result, but rather consult your certified medical experts for their recommendations.

    Visitor reports

    One visitor reported time for results

    What is the time duration Anxit Forte drug must be taken for it to be effective or for it to reduce the symptoms?
    Most chronic conditions need at least some time so the dose and the drug action gets adjusted to the body to get the desired effect. The stastistics say sDrugs.com website users needed 1 day to notice the result from using Anxit Forte drug. The time needed to show improvement in health condition after using the medicine Anxit Forte need not be same for all the users. It varies based on other factors.
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    The information was verified by Dr. Arunabha Ray, MD Pharmacology

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