Amplibenzatin Bronquial

Ampicillin Sodium:

• Pharmacological action
• Pharmacokinetics
• Why is Amplibenzatin Bronquial prescribed?
• Dosage and administration
• Amplibenzatin Bronquial (Ampicillin Sodium) side effects, adverse reactions
• Amplibenzatin Bronquial contraindications
• Using during pregnancy and breastfeeding
• Special instructions
• Amplibenzatin Bronquial drug interactions
• Amplibenzatin Bronquial in case of emergency / overdose
• Amplibenzatin Bronquial (Ampicillin Sodium) reviews

Pharmacological action

Amplibenzatin Bronquial is an antibiotic of semisynthetic broad-spectrum penicillin group. This medication has a bactericidal effect by suppressing the synthesis of bacterial cell walls. Amplibenzatin Bronquial (Ampicillin Sodium) is active against aerobic gram-positive bacteria: Staphylococcus spp. (with the exception of strains producing penicillinase), Streptococcus spp., Enterococcus spp., Listeria monocytogenes; aerobic gram-negative bacteria: Neisseria gonorrhoeae, Neisseria meningitidis, Escherichia coli, Shigella spp., Salmonella spp., Bordetella pertussis, some strains of Haemophilus influenzae. Amplibenzatin Bronquial (Ampicillin Sodium) destroyed by penicillinase. This drug is acid-resistant.

Pharmacokinetics

After oral administration Amplibenzatin Bronquial (Ampicillin Sodium) is well absorbed from the gastrointestinal tract. This medicine is distributed in most organs and tissues; crosses the placental barrier, poorly penetrates the BBB. When inflammation of the meninges, BBB permeability increases dramatically. 30% of Amplibenzatin Bronquial (Ampicillin Sodium) is metabolized in the liver. This medication is excreted in the urine and bile.

Why is Amplibenzatin Bronquial prescribed?

Infectious-inflammatory diseases caused by organisms susceptible to Amplibenzatin Bronquial (Ampicillin Sodium): including ear infections, throat, nose, odontogenic infections, bronchopulmonary infections, acute and chronic urinary tract infections, gastrointestinal infections (including salmonella, cholecystitis), gynecological infections, meningitis, endocarditis, septicemia, sepsis, rheumatic fever, erysipelas, scarlet fever, infections of skin and soft tissues.

Dosage and administration

The dosing regimen of Amplibenzatin Bronquial is set individually depending on the severity, localization of infection and sensitivity of the pathogen.

For adults for oral administration a single dose of this medication is 250-500 mg, the multiplicity of the reception is 4 times / day. The dose for children weighing up to 20 kg is 12.5-25 mg / kg every 6 hours.

For IV and IM using the single dose for adults is 250-500 mg every 4-6 hours; for children the single dose is 25-50 mg / kg.

The duration of treatment depends on the localization of infection and features of the disease.

The maximum oral daily dose for adults is 4 g, for IM and IV administration - 14 g.

Amplibenzatin Bronquial (Ampicillin Sodium) side effects, adverse reactions

Allergic reactions: urticaria, erythema, angioedema, rhinitis, conjunctivitis, rarely - fever, joint pain, eosinophilia, extremely rare - anaphylactic shock.

Digestive system: nausea, vomiting.

The effects caused by chemotherapeutic action: oral candidiasis, vaginal candidiasis, intestinal dysbiosis, colitis caused by Clostridium difficile.

Amplibenzatin Bronquial contraindications

Infectious mononucleosis, lymphatic leukemia, increased sensitivity to Amplibenzatin Bronquial (Ampicillin Sodium) and other penicillins, abnormal liver function.

Using during pregnancy and breastfeeding

Perhaps the use of Amplibenzatin Bronquial during pregnancy if it may be needed. Amplibenzatin Bronquial (Ampicillin Sodium) is excreted in breast milk in low concentrations. If necessary to use Amplibenzatin Bronquial (Ampicillin Sodium) in the lactation period it should be solved the issue of termination of breastfeeding.

Category effects on the fetus by FDA - B.

Special instructions

In the course of treatment with Amplibenzatin Bronquial (Ampicillin Sodium) there is need the regular control of renal function, liver and peripheral blood picture. Patients with impaired renal function requires correction dosing regimen in accordance with the values of CCr.

When used in high doses in patients with renal insufficiency it may be toxic effects on the CNS.

For using of Amplibenzatin Bronquial (Ampicillin Sodium) in patients with bacteremia (sepsis) it can be bacteriolysis reaction (Jarisch-Herxheimer reaction).

Amplibenzatin Bronquial drug interactions

Simultaneous administration of Amplibenzatin Bronquial (Ampicillin Sodium) with bactericidal antibiotics (including aminoglycosides, cephalosporins, cycloserine, vancomycin, rifampicin) there is manifested synergism; with bacteriostatic antibiotics (including macrolides, chloramphenicol, lincosamides, tetracyclines, sulfonamides) - antagonism.

Amplibenzatin Bronquial (Ampicillin Sodium) enhances the effect of indirect anticoagulants by inhibiting the intestinal microflora, reduces the synthesis of vitamin K and prothrombin index.

Amplibenzatin Bronquial (Ampicillin Sodium) decreases the effect of drugs in the process of metabolism which produce PABA.

Probenecid, diuretics, allopurinol, phenylbutazone, NSAIDs decrease the tubular secretion of Amplibenzatin Bronquial (Ampicillin Sodium) which may be accompanied by an increase in its concentration in blood plasma.

Antacids, glucosamine, laxatives, aminoglycosides slow down and reduce the absorption of Amplibenzatin Bronquial (Ampicillin Sodium) Upha Corporation. Ascorbic acid increases the absorption of Amplibenzatin Bronquial (Ampicillin Sodium).

Amplibenzatin Bronquial (Ampicillin Sodium) decreases the effectiveness of oral contraceptives.

Amplibenzatin Bronquial in case of emergency / overdose

Symptoms: the toxic effect on the central nervous system (especially in patients with renal insufficiency), nausea, vomiting, diarrhea, impaired water and electrolyte balance (as a consequence of vomiting and diarrhea).

Treatment: gastric lavage, activated charcoal, saline laxatives, a maintain of water and electrolyte balance, symptomatic therapy. This drug is derived by means of hemodialysis.

Chlorpheniramine Maleate:

• Uses
• Warnings
• Directions
• Other information
• Inactive ingredients
• Questions? comments?
• Amplibenzatin Bronquial (Chlorpheniramine Maleate) reviews

Drug Facts

Uses

temporarily relieves these symptoms due to the common cold, hay fever (allergic rhinitis) or other upper respiratory allergies

• runny nose
• sneezing
• itching of the nose or throat
• itchy, watery eyes
• nasal congestion
• reduces swelling of nasal passages

Warnings

Do not exceed recommended dosage.

Do not use this product in a child who is

• now taking a prescription monoamine oxidase inhibitor (certain drugs for depression, psychiatric, or emotional conditions, or Parkinson's disease), or for 2 weeks after stopping the MAOI drug. If you do not know if your child's prescription drug contains an MAOI, ask a doctor or pharmacist before giving this product.

Ask a doctor before use if a child has

• a breathing problem such as chronic bronchitis
• glaucoma
• heart disease
• high blood pressure
• thyroid disease
• diabetes mellitus

Ask a doctor before use if a child is taking sedatives or tranquilizers

When using this product

• excitability may occur, especially in children
• may cause drowsiness
• sedatives and tranquilizers may increase drowsiness effect

Stop use and ask a doctor if

• nervousness, dizziness, or sleeplessness occur
• new symptoms occur

Keep out of reach of children. In case of accidental overdose, seek professional help or contact a Poison Control Center immediately.

Directions

Do not exceed recommended dosage.

Other information

Store at 59°-86°F (15°-30°C)

Inactive ingredients

Applesauce Flavor, Citric Acid, FD&C Blue #1, FD&C Yellow #6, Glycerin, Methyl Paraben, Potassium Citrate, Potassium Sorbate, Propyl Paraben, Propylene Glycol, Purified Water, Sucralose

Questions? Comments?

Call 1-800-543-9560

Rev. 05/11

E

NEW

FORMULA

NDC 00485-0096-02

Amplibenzatin Bronquial (Chlorpheniramine Maleate)

Pediatric Drops

Antihistamine ▪ Nasal Decongestant

Sugar Free ▪ Alcohol Free ▪ Gluten Free

FOR PROFESSIONAL USE ONLY

Each 1 mL for oral administration

contains:

Amplibenzatin Bronquial (Chlorpheniramine Maleate) Maleate

2 mg

Phenylephrine HCl

5 mg

APPLESAUCE FLAVOR

Tamper evident by foil seal under cap.

Do not use if foil seal is broken or missing.

Manufactured for:

EDWARDS

Pharmaceuticals, Inc.

Ripley, MS 38663

2 fl. oz. (60 mL)