DRUGS & SUPPLEMENTS

Aflumicort

Name: Aflumicort drug & pharmaceuticals. Available Forms, Doses, Prices
Creator: sdrugs.com
Published: 2021-11-11T10:10:10+00:00

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Aflumicort uses

Pharmacological action
Pharmacokinetics
Why is Aflumicort prescribed?
Dosage and administration
Aflumicort side effects, adverse reactions
Aflumicort contraindications
Using during pregnancy and breastfeeding
Special instructions
Aflumicort drug interactions
Aflumicort in case of emergency / overdose
Aflumicort reviews

Pharmacological action

Aflumicort is an antifungal drug from the group of triazole derivatives. Inhibits the synthesis of ergosterol disrupting the permeability of the cell wall. This medication is active against Candida, Microsporum, Cryptococcus neoformans, Trichophyton.

Pharmacokinetics

Aflumicort is well absorbed after oral administration. Simultaneous ingestion does not affect absorption. The bioavailability is 90%. Aflumicort is widely distributed in tissues and organs of the body. Its concentration in breast milk, joint fluid, saliva, sputum, vaginal secretions and peritoneal fluid are similar to those in blood plasma. The concentration in the cerebrospinal fluid is 50-90% of the level in blood plasma, regardless of the presence of inflammation of the meninges. In the stratum corneum, epidermis, dermis and sweat fluid concentrations reach values exceeding the concentration in blood plasma. T_1/2 is 30 h. Aflumicort is excreted by the kidneys, 80% of the administered dose in an unmodified form.

Why is Aflumicort prescribed?

Cryptococcosis, systemic candidiasis, candidiasis of the mucous membranes, vaginal candidiasis, prevention of fungal infections in patients with lowered immunity (including AIDS patients). Fungal infections of skin, including athlete's foot, body, groin, pityriasis versicolor, onychomycosis. Deep endemic mycoses, including coccidioidomycosis, paracoccidioidomycosis, sporotrichosis and histoplasmosis in patients with normal immunity.

Dosage and administration

Dosing regimen of Aflumicort is individual. This medication is prescribed for oral and IV administration. Depending on the testimony of the daily dose is 50-400 mg, the multiplicity of application is 1 times / day. If impaired renal function the dose of Aflumicort should be reduced.

Aflumicort side effects, adverse reactions

Digestive system: nausea, abdominal pain, diarrhea, flatulence.

CNS: headache, dizziness.

Allergic reactions: skin rash, anaphylactic reactions.

Aflumicort contraindications

Pregnancy, children up to age 1 year, increased sensitivity to Aflumicort and triazole compounds.

Using during pregnancy and breastfeeding

Aflumicort is contraindicated during pregnancy and lactation.

If necessary using this medication during lactation it should solve the issue of termination of breastfeeding. Category effects on the fetus by FDA - C.

Special instructions

Aflumicort should be used with caution in patients with severe impaired liver or kidney diseases.

Therapy can be started before the results of seeding and other laboratory tests. However, an anti-infective therapy should be corrected accordingly when the results of these studies will be known.

Aflumicort drug interactions

Simultaneous administration of Aflumicort with:

coumarin anticoagulants marked increase in prothrombin time.

rifampicin observed shortening of the half-life of Aflumicort. Aflumicort Sorres Pharma increases the half-life of oral hypoglycemic agents - sulfonylureas in healthy people. Simultaneous use of Aflumicort and oral hypoglycemic agents in diabetic patients is allowed, however, the physician should bear in mind the possibility of hypoglycemia.

Aflumicort in case of emergency / overdose

Symptoms: nausea, vomiting, diarrhea and seizures in severe cases.

Treatment: gastric lavage, forced diuresis, hemodialysis (three-hour dialysis reduces the plasma concentrations of approximately 50%), symptomatic therapy.

Aflumicort pharmaceutical active ingredients containing related brand and generic drugs:

Fluconazole

Aflumicort available forms, composition, doses:

Aflumicort destination | category:

Human:
Antifungals
Azoles
Eye anti-infectives and antiseptics
Topical antifungals and antiparasites

Aflumicort Anatomical Therapeutic Chemical codes:

D01AC15 - Fluconazole
J02AC01 - Fluconazole

Aflumicort pharmaceutical companies:

Compania Anonima Farmaceutica

References

Dailymed."FLUCONAZOLE TABLET [BRYANT RANCH PREPACK]". https://dailymed.nlm.nih.gov/dailym... (accessed August 28, 2018).
Dailymed."FLUCONAZOLE: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailym... (accessed August 28, 2018).
"fluconazole". https://pubchem.ncbi.nlm.nih.gov/co... (accessed August 28, 2018).

Frequently asked Questions

Can i drive or operate heavy machine after consuming Aflumicort?

Depending on the reaction of the Aflumicort after taken, if you are feeling dizziness, drowsiness or any weakness as a reaction on your body, Then consider Aflumicort not safe to drive or operate heavy machine after consumption. Meaning that, do not drive or operate heavy duty machines after taking the capsule if the capsule has a strange reaction on your body like dizziness, drowsiness. As prescribed by a pharmacist, it is dangerous to take alcohol while taking medicines as it exposed patients to drowsiness and health risk. Please take note of such effect most especially when taking Primosa capsule. It's advisable to consult your doctor on time for a proper recommendation and medical consultations.

Is Aflumicort addictive or habit forming?

Medicines are not designed with the mind of creating an addiction or abuse on the health of the users. Addictive Medicine is categorically called Controlled substances by the government. For instance, Schedule H or X in India and schedule II-V in the US are controlled substances.

Please consult the medicine instruction manual on how to use and ensure it is not a controlled substance.In conclusion, self medication is a killer to your health. Consult your doctor for a proper prescription, recommendation, and guidiance.

Review

sdrugs.com conducted a study on Aflumicort, and the result of the survey is set out below. It is noteworthy that the product of the survey is based on the perception and impressions of the visitors of the website as well as the views of Aflumicort consumers. We, as a result of this, advice that you do not base your therapeutic or medical decisions on this result, but rather consult your certified medical experts for their recommendations.