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DRUGS & SUPPLEMENTS
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Omezol
How is the drug helping you? |
Omezol uses
Pharmacological action
Omezol is an inhibitor of H+ K+ ATPase. This medication inhibits the activity of H+-K+-ATPase in gastric parietal cells and thus blocks the final stage of hydrochloric acid secretion. This leads to a reduction in basal and stimulated secretion, regardless of the nature of the stimulus. Due to the reduction of acid secretion Omezol reduces or normalizes the effects of acid in the esophagus in patients with reflux esophagitis.
Omezol has a bactericidal effect on Helicobacter pylori. Eradication of H. pylori when Omezol used with antibiotics allows to quickly arrest the symptoms, to take a high degree of healing of damaged mucosa and persistent long-term remission and reduce the likelihood of bleeding from the gastrointestinal tract.
Pharmacokinetics
After oral administration Omezol is rapidly absorbed from the gastrointestinal tract. This drug penetrates the parietal cells of gastric mucosa. Plasma protein binding is about 95%. Omezol is biotransformed in the liver. Excreted by the kidneys - 72-80%, in the faeces - about 20%. T1/2 is 0.5-1 h. In patients with chronic liver diseases T1/2 increases up to 3 hours.
Why is Omezol prescribed?
Gastric ulcer and duodenal ulcer in acute phase (including associated with Helicobacter pylori), reflux esophagitis, Zollinger-Ellison syndrome, erosive and ulcerative lesions of gastric and duodenal ulcers associated with taking NSAIDs.
Dosage and administration
The dosing regimen of Omezol is individual. When this medication is administered orally of the single dose is 20-40 mg. The daily dose is 20-80 mg, the frequency of use is 1-2 times / day. The duration of treatment is 2-8 weeks.
Omezol side effects, adverse reactions
Digestive system: rarely - nausea, diarrhea, constipation, abdominal pain, flatulence.
CNS: rarely - headache, dizziness, weakness.
Hemopoietic system: in some cases - anemia, eosinopenia, neutropenia, thrombocytopenia.
Urinary system: in some cases - hematuria, proteinuria.
Musculoskeletal system: in some cases - arthralgia, muscle weakness, myalgia.
Allergic reactions: rarely - skin rash.
Omezol contraindications
Chronic liver disease, hypersensitivity to Omezol.
Using during pregnancy and breastfeeding
In the absence of clinical experience with Omezol it is not recommended to use this drug during pregnancy. If necessary to use during Omezol lactation it should been solve the issue of termination of breastfeeding.
Category effects on the fetus by FDA - C.
Special instructions
Before the treatment with Omezol it is necessary to exclude the possibility of a malignant process because Omezol treatment can mask symptoms and delay the correct diagnosis.
Therapy with Omezol may affects results of laboratory studies of liver and gastrin concentrations in blood plasma.
Due to lack of experience in clinical application of Omezol this medicine is not recommended for children.
Omezol drug interactions
This medication alters the bioavailability of any drug, absorption depends on pH (ketoconazole, iron salts, etc.). Omezol slows down the elimination of drugs metabolized in the liver by microsomal oxidation (warfarin, diazepam, phenytoin, etc.).
Omezol enhances the action of coumarin and diphenine, does not change - NSAIDs. This drug increases (relative) the concentration of clarithromycin in the blood; may increases the leukopenic and thrombocytopenic effects of depressants hematopoiesis drugs. Substance for intravenous infusion is compatible only with saline and dextrose (using other solvents may decrease the stability of Omezol due to changes in pH of infusion medium).
Omezol in case of emergency / overdose
Symptoms: dry mouth, nausea, blurred vision, headache, increased sweating, flushing, tachycardia, drowsiness, confusion.
Treatment: symptomatic, dialysis is ineffective.
Omezol pharmaceutical active ingredients containing related brand and generic drugs:
Omezol available forms, composition, doses:
Omezol destination | category:
Omezol Anatomical Therapeutic Chemical codes:
Omezol pharmaceutical companies:
References
- Dailymed."OMEPRAZOLE CAPSULE, DELAYED RELEASE [LAKE ERIE MEDICAL DBA QUALITY CARE PRODUCTS LLC]". https://dailymed.nlm.nih.gov/dailym... (accessed August 28, 2018).
- Dailymed."OMEPRAZOLE MAGNESIUM: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailym... (accessed August 28, 2018).
- "omeprazole". https://pubchem.ncbi.nlm.nih.gov/co... (accessed August 28, 2018).
Frequently asked Questions
Can i drive or operate heavy machine after consuming Omezol?Depending on the reaction of the Omezol after taken, if you are feeling dizziness, drowsiness or any weakness as a reaction on your body, Then consider Omezol not safe to drive or operate heavy machine after consumption. Meaning that, do not drive or operate heavy duty machines after taking the capsule if the capsule has a strange reaction on your body like dizziness, drowsiness. As prescribed by a pharmacist, it is dangerous to take alcohol while taking medicines as it exposed patients to drowsiness and health risk. Please take note of such effect most especially when taking Primosa capsule. It's advisable to consult your doctor on time for a proper recommendation and medical consultations.
Is Omezol addictive or habit forming?Medicines are not designed with the mind of creating an addiction or abuse on the health of the users. Addictive Medicine is categorically called Controlled substances by the government. For instance, Schedule H or X in India and schedule II-V in the US are controlled substances.
Please consult the medicine instruction manual on how to use and ensure it is not a controlled substance.In conclusion, self medication is a killer to your health. Consult your doctor for a proper prescription, recommendation, and guidiance.
Review
sdrugs.com conducted a study on Omezol, and the result of the survey is set out below. It is noteworthy that the product of the survey is based on the perception and impressions of the visitors of the website as well as the views of Omezol consumers. We, as a result of this, advice that you do not base your therapeutic or medical decisions on this result, but rather consult your certified medical experts for their recommendations.Visitor reports
Visitor reported useful
No survey data has been collected yetVisitor reported side effects
No survey data has been collected yetOne visitor reported price estimates
What is your opinion about drug cost? Did you feel the cost is apt, or did you feel it is expensive?The report given by the sdrugs.com website users shows the following figures about several people who felt the medicine Omezol is expensive, and the medicine is not expensive. The results are mixed. The perception of the cost of the medicine to be expensive or not depends on the brand name of the medicine, country, and place where it is sold, and the affordability of the patient. You can choose a generic drug in the place of the branded drug to save the cost. The efficiency of the medicine will not vary if it is generic or a branded one.
| Visitors | % | ||
|---|---|---|---|
| Not expensive | 1 | 100.0% | |
One visitor reported frequency of use
How often in a day do you take the medicine?Are you taking the Omezol drug as prescribed by the doctor?
Few medications can be taken 3 times in a day more than prescribed when the doctor's advice mentions the medicine can be taken according to frequency or severity of symptoms. Most times, be very careful and clear about the number of times you are taking the medication. The report of sdrugs.com website users about the frequency of taking the drug Omezol is mentioned below.
| Visitors | % | ||
|---|---|---|---|
| 3 times in a day | 1 | 100.0% | |
Visitor reported doses
No survey data has been collected yetVisitor reported time for results
No survey data has been collected yetVisitor reported administration
No survey data has been collected yetOne visitor reported age
| Visitors | % | ||
|---|---|---|---|
| 16-29 | 1 | 100.0% | |
Visitor reviews
There are no reviews yet. Be the first to write one! |
The information was verified by Dr. Rachana Salvi, MD Pharmacology