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DRUGS & SUPPLEMENTS
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Active ingredient: Acetaminophen
When are you taking this medicine? |
Acetaminophen uses
Pharmacological action
Acetaminophen is an analgesic-antipyretic. It has analgesic, antipyretic and weak anti-inflammatory action. The mechanism of action is associated with inhibition of prostaglandin synthesis, the predominant influence on the thermoregulation center in the hypothalamus, enhances heat transfer.
Why is Acetaminophen prescribed?
Pain weak and moderate intensity of different genesis. Fever in infectious and inflammatory diseases.
Acetaminophen dosage and administration
Oral or rectally adults and adolescents with a body weight over 60 kg is used in a single dose of 500 mg, the multiplicity of admission - up to 4 times / Maximum duration of treatment - 5-7 days.
Maximum dose: single - 1 g, daily - 4 g.
Single dose for oral administration for children aged 6-12 years - 250-500 mg, 1-5 years - 120-250 mg, from 3 months to 1 year - 60-120 mg, up to 3 months - 10 mg / kg. Single dose rectal in children aged 6-12 years - 250-500 mg, 1-5 years - 125-250 mg.
Multiplicity - 4 at intervals of not less than 4 h. The maximum duration of treatment - 3 days.
Maximum dose: 4 single dose per day.
Acetaminophen side effects, adverse reactions
Digestive system: rarely - dyspepsia; long-term use at high doses - hepatotoxic effects, methemoglobinemia, renal dysfunction and liver, hypochromic anemia. Hemopoietic system: rarely - thrombocytopenia, leukopenia, pancytopenia, neutropenia, agranulocytosis. Allergic reactions: rarely - skin rash, itching, hives.
Contraindications
Chronic active alcoholism, increased sensitivity to Acetaminophen, marked disturbances of liver function and / or kidney disease, anemia, pregnancy.
Using during pregnancy and breastfeeding
Acetaminophen crosses the placental barrier. So far, no observed adverse effects of Acetaminophen on the fetus in humans.
Acetaminophen is excreted in breast milk: the content in milk was 0.04-0.23% of the dose adopted mother.
If necessary, use of Acetaminophen during pregnancy and lactation (breastfeeding) should carefully weigh the potential benefits of therapy for the mother and the potential risk to the fetus or child.
In experimental studies found no embryotoxic, teratogenic and mutagenic action of Acetaminophen.
Special Instructions
Acetaminophen is used with caution in patients with disorders of the liver and kidneys, with benign hyperbilirubinemia, as well as in elderly patients.
With prolonged use of Acetaminophen is necessary to monitor patterns of peripheral blood and functional state of the liver.
Used for treatment of premenstrual tension syndrome in combination with pamabrom and mepyramine (Histamine H1-receptors blocker).
Acetaminophen Drug Interactions
With the simultaneous use with inducers of microsomal liver enzymes, means having hepatotoxic effect, increasing the risk of hepatotoxic action of Acetaminophen.
With the simultaneous use of anticoagulants may be slight to moderate increase in prothrombin time.
With the simultaneous use of anticholinergics may decrease absorption of Acetaminophen.
With the simultaneous use of oral contraceptives accelerated excretion of Acetaminophen from the body and may reduce its analgesic action.
With the simultaneous use with urological means reduced their effectiveness.
With the simultaneous use of activated charcoal reduced bioavailability of Acetaminophen.
When Acetaminophen applied simultaneously with diazepam may decrease excretion of diazepam.
There have been reports about the possibility of enhancing mielodepression effect of zidovudine while applying with Acetaminophen. A case of severe toxic liver injury.
Described cases of toxic effects of Acetaminophen, while the use of isoniazid.
When applied simultaneously with carbamazepine, phenytoin, phenobarbital, primidonom decreases the effectiveness of Acetaminophen, which is caused by an increase in its metabolism and excretion from the body. Cases of hepatotoxicity, while the use of Acetaminophen and phenobarbital.
In applying cholestyramine a period of less than 1 h after administration of Acetaminophen may decrease of its absorption.
At simultaneous application with lamotrigine moderately increased excretion of lamotrigine from the body.
With the simultaneous use of metoclopramide may increase absorption of Acetaminophen and its increased concentration in blood plasma.
When applied simultaneously with probenecid may decrease clearance of Acetaminophen, with rifampicin, sulfinpyrazone - may increase clearance of Acetaminophen due to increasing its metabolism in the liver.
At simultaneous application of Acetaminophen with ethinylestradiol increases absorption of Acetaminophen from the gut.
Enhances the effect of indirect anticoagulants (coumarin derivatives and indandione). Antipyretic and analgesic activity of caffeine increases, reduce - rifampicin, phenobarbital and alcohol (accelerated biotransformation, inducing microsomal liver enzymes).
Acetaminophen in case of emergency / overdose
At a reception in toxic doses (10-15 g in adults) may develop liver necrosis.
Symptoms of overdose may include: nausea, vomiting, loss of appetite, sweating, extreme tiredness, unusual bleeding or bruising, pain in the upper right part of the stomach, yellowing of the skin or eyes, flu-like symptoms
Acetaminophen available forms, composition, doses:
| Price | |
| Acephen 120 mg suppository | 0.54 USD |
| Acephen 325 mg suppository | 0.54 USD |
| Acephen 650 mg suppository | 0.55 USD |
| Acetaminophen 120 mg suppository | 0.38 USD |
| Acetaminophen 160 mg tablet chw | 0.09 USD |
| Acetaminophen 325 mg suppository | 0.44 USD |
| Acetaminophen 325 mg tablet | 0.03 USD |
| Acetaminophen 500 mg caplet | 0.03 USD |
| Acetaminophen 500 mg gelcap | 0.06 USD |
| Acetaminophen 500 mg geltab | 0.11 USD |
| Acetaminophen 500 mg tablet | 0.11 USD |
| Acetaminophen 650 mg caplet | 0.12 USD |
| Acetaminophen 650 mg suppository | 0.39 USD |
| Acetaminophen 80 mg tablet chew | 0.07 USD |
| Acetaminophen pm caplet | 0.08 USD |
| Acetaminophen powder dense | 0.07 USD |
| Apap 325 mg tablet | 0.07 USD |
| Apap child's 80 mg tablet chew | 0.07 USD |
| Apap jr str 160 mg tablet chew | 0.12 USD |
| Apap-butalbital 325-50 tablet | 0.38 USD |
| CVS Pharmacy acetaminophen 325 mg tablet | 0.04 USD |
| CVS Pharmacy non-aspirin 500 mg caplet | 0.06 USD |
| CVS Pharmacy non-aspirin 500 mg tablet | 0.06 USD |
| CVS Pharmacy pain relief 500 mg gelcap | 0.06 USD |
| CVS Pharmacy pain rlf cool ice caplet | 0.06 USD |
| Caplets; Oral; Acetaminophen 325 mg | |
| Caplets; Oral; Acetaminophen 500 mg | |
| Child tylenol cold/cough tablet | 0.17 USD |
| Child tylenol cough-runny nose | 0.05 USD |
| Child tylenol cough-sore thrt | 0.05 USD |
| Child's tylenol 80 mg meltaway | 0.11 USD |
| Childrens apap 80 mg tablet chew | 0.17 USD |
| Childs tylenol cold-aller susp | 0.04 USD |
| Childs tylenol cold-cough susp | 0.05 USD |
| Childs tylenol plus cold susp | 0.04 USD |
| Childs tylenol plus flu susp | 0.04 USD |
| Clemastine fum 2.68 mg tablet | 0.86 USD |
| Co-gesic 5-500 tablet | 0.92 USD |
| Darvocet A500 100-500 mg tablet | 1.38 USD |
| Darvocet a500 tablet | 1.5 USD |
| Darvocet-N 100 100-650 mg tablet | 2.33 USD |
| Darvocet-N 50 50-325 mg tablet | 0.73 USD |
| Darvocet-n 100 tablet | 1.72 USD |
| Darvocet-n 50 tablet | 1.14 USD |
| Drixoral cold & allergy tablet sa | 0.4 USD |
| Drops; Oral; Acetaminophen 80 mg / ml | |
| Elixir; Oral; Acetaminophen 32 mg / ml | |
| Eql pain relief 325 mg tablet | 0.06 USD |
| Eql pain relief 500 mg caplet | 0.1 USD |
| Eql pain relief 500 mg geltab | 0.1 USD |
| Excedrin back & body caplet | 0.1 USD |
| Excedrin extra strength caplet | 0.14 USD |
| Excedrin menstrual cmplt gelcap | 0.19 USD |
| Excedrin migraine caplet | 0.14 USD |
| Excedrin migraine geltabs | 0.15 USD |
| Excedrin pm 500-38 mg tablet | 0.08 USD |
| Excedrin quicktabs | 0.2 USD |
| Excedrin sinus headache caplet | 0.1 USD |
| Excedrin sinus headache tablet | 0.14 USD |
| Excedrin tension headache caplet | 0.1 USD |
| Excedrin tension headache tablet | 0.14 USD |
| Feverall 120 mg suppository | 0.8 USD |
| Feverall 325 mg suppository | 0.8 USD |
| Feverall 650 mg suppository | 0.43 USD |
| Feverall 80 mg suppository | 0.8 USD |
| Genapap 325 mg tablet | 0.03 USD |
| Genapap 500 mg tablet | 0.03 USD |
| Hydrocodone-apap 10-325 tablet | 0.7 USD |
| Hydrocodone-apap 10-500 tablet | 0.53 USD |
| Hydrocodone-apap 10-650 tablet | 0.37 USD |
| Hydrocodone-apap 10-660 tablet | 0.61 USD |
| Hydrocodone-apap 10-750 tablet | 1.12 USD |
| Hydrocodone-apap 2.5-500 tablet | 0.33 USD |
| Hydrocodone-apap 5-325 tablet | 0.54 USD |
| Hydrocodone-apap 7.5-325 tablet | 0.62 USD |
| Hydrocodone-apap 7.5-500 tablet | 0.12 USD |
| Hydrocodone-apap 7.5-650 tablet | 0.93 USD |
| Hydrocodone-apap 7.5-750 tablet | 0.13 USD |
| Jr. tylenol 160 mg meltaways | 0.19 USD |
| Liquid; Oral; Acetaminophen 80 mg / 5 ml | |
| Mapap 325 mg tablet | 0.05 USD |
| Maxapap 325 mg tablet | 0.01 USD |
| Maxapap 500 mg caplet | 0.01 USD |
| Maxapap 500 mg tablet | 0.01 USD |
| Momentum caplet | 0.23 USD |
| Non-aspirin 500 mg geltab | 0.05 USD |
| Non-aspirin 500 mg tablet | 0.04 USD |
| Norco 10-325 mg tablet | 2.14 USD |
| Norco 10-325 tablet | 2.76 USD |
| Norco 5-325 mg tablet | 1.43 USD |
| Norco 5-325 tablet | 1.19 USD |
| Norco 7.5-325 mg tablet | 1.61 USD |
| Norco 7.5-325 tablet | 2.77 USD |
| Pain relief 325 mg tablet | 0.02 USD |
| Pain relief 500 mg caplet | 0.06 USD |
| Pain relief 500 mg tablet | 0.03 USD |
| Pain relief without asa tablet | 0.05 USD |
| Pain reliever 160 mg tablet | 0.08 USD |
| Pain reliever 325 mg tablet | 0.06 USD |
| Pain reliever 500 mg caplet | 0.09 USD |
| Pain reliever 500 mg gelcap | 0.03 USD |
| Pain reliever 500 mg geltab | 0.04 USD |
| Pain reliever 500 mg tablet | 0.03 USD |
| Pain reliever w-o asa 325 mg | 0.02 USD |
| Phrenilin 50-325 mg tablet | 1.63 USD |
| Phrenilin Forte 50-650 mg capsule | 5.24 USD |
| Phrenilin forte capsule | 4.46 USD |
| Phrenilin tablet | 1.32 USD |
| Propoxyphen-apap 100-325 mg tablet | 2.66 USD |
| Propoxyphen-apap 100-500 mg tablet | 1.85 USD |
| Propoxyphen-apap 100-650 mg tablet | 0.55 USD |
| Propoxyphene-apap 50-325 mg tablet | 0.93 USD |
| Q-pap ex-str 500 mg tablet | 0.04 USD |
| Ra acetaminophen pm caplet | 0.04 USD |
| Sedapap 50-650 mg tablet | 0.92 USD |
| Soba pain rel 500 mg gelcap | 0.1 USD |
| Soba pain rel xs 500 mg tablet | 0.07 USD |
| Soba pain reliever 500 mg tablet | 0.06 USD |
| Solution; Oral; Acetaminophen 160 mg / 5 ml | |
| Solution; Oral; Acetaminophen 80 mg / 5 ml | |
| Solution; Oral; Acetaminophen 80 mg / ml | |
| Suppositories; Rectal; Acetaminophen 120 mg | |
| Suppositories; Rectal; Acetaminophen 325 mg | |
| Suppositories; Rectal; Acetaminophen 650 mg | |
| Syrup; Oral; Acetaminophen 160 mg / 5 ml | |
| Tablets, Chewable; Oral; Acetaminophen 160 mg | |
| Tablets, Extended Release; Oral; Acetaminophen 650 mg | |
| Tablets; Oral; Acetaminophen 160 mg | |
| Tablets; Oral; Acetaminophen 325 mg | |
| Tablets; Oral; Acetaminophen 500 mg | |
| Tavist max-str sinus caplet | 0.17 USD |
| Tavist nd 10 mg tablet | 0.74 USD |
| Tavist-1 1.34 mg tablet | 0.5 USD |
| Tencon tablet | 1.01 USD |
| Tylenol 100 325 mg tablet Bottle | 16.98 USD |
| Tylenol 325 mg tablet | 0.07 USD |
| Tylenol 8 hour 650 mg caplet | 0.1 USD |
| Tylenol allergy complete caplet | 0.19 USD |
| Tylenol allergy complete gelcap | 0.19 USD |
| Tylenol allergy m-s caplet | 0.22 USD |
| Tylenol allergy m-s night caplet | 0.2 USD |
| Tylenol allergy multi-symptom | 0.16 USD |
| Tylenol allergy sinus caplet | 0.17 USD |
| Tylenol allergy sinus gelcap | 0.19 USD |
| Tylenol allergy sinus geltab | 0.19 USD |
| Tylenol arthritis caplet sa | 0.13 USD |
| Tylenol arthritis geltab | 0.18 USD |
| Tylenol chest congestion caplet | 0.2 USD |
| Tylenol cold & flu severe liq | 0.02 USD |
| Tylenol cold caplet | 0.17 USD |
| Tylenol cold gelcap | 0.23 USD |
| Tylenol cold head cong caplet | 0.21 USD |
| Tylenol cold head congest caplet | 0.2 USD |
| Tylenol cold head congestion | 0.23 USD |
| Tylenol cold m-s severe day liquid | 0.02 USD |
| Tylenol cold multi-symp caplet | 0.21 USD |
| Tylenol cold multi-symp gelcap | 0.23 USD |
| Tylenol cold multi-symptom caplet | 0.22 USD |
| Tylenol cold relief caplet | 0.15 USD |
| Tylenol cold relief nightime | 0.16 USD |
| Tylenol cold severe congestion | 0.21 USD |
| Tylenol cough & sore throat lq | 0.02 USD |
| Tylenol day & night value pack | 0.12 USD |
| Tylenol es for arthritis pain | 0.08 USD |
| Tylenol ex-str 500 mg caplet | 0.08 USD |
| Tylenol ex-str 500 mg gelcap | 0.05 USD |
| Tylenol ex-str 500 mg geltab | 0.09 USD |
| Tylenol ex-str 500 mg tablet | 0.13 USD |
| Tylenol flu max-strn gelcap | 0.24 USD |
| Tylenol flu nighttime gelcap | 0.19 USD |
| Tylenol nighttime liquid | 0.02 USD |
| Tylenol p.m. ex-str geltab | 0.1 USD |
| Tylenol pm ex-strength caplet | 0.1 USD |
| Tylenol pm ex-strength gelcap | 0.16 USD |
| Tylenol pm ex-strength geltab | 0.08 USD |
| Tylenol pm liquid | 0.02 USD |
| Tylenol severe allergy caplet | 0.17 USD |
| Tylenol sinus caplet | 0.21 USD |
| Tylenol sinus congest-pain caplet | 0.19 USD |
| Tylenol sinus congestion&pain | 0.2 USD |
| Tylenol sinus gelcap | 0.19 USD |
| Tylenol sinus geltab | 0.19 USD |
| Tylenol sinus nighttime caplet | 0.19 USD |
| Tylenol sore throat liquid | 0.02 USD |
| Tylenol with Codeine #3 300-30 mg tablet | 1.1 USD |
| Tylenol with Codeine #4 300-60 mg tablet | 1.65 USD |
| Ultracet 37.5-325 mg tablet | 1.95 USD |
| Ultracet tablet | 1.79 USD |
| Women's tylenol 500-25 capsule | 0.16 USD |
Indications and Usages:
ATC codes:
ICD-10 codes:
Acetaminophen destination | category:
Drugs with same active ingredients (Pharmaceutical companies):
References
- Dailymed."FEVERALL INFANTS (ACETAMINOPHEN) SUPPOSITORY [ACTAVIS MID ATLANTIC LLC]". https://dailymed.nlm.nih.gov/dailym... (accessed August 28, 2018).
- Dailymed."ACETAMINOPHEN; ASPIRIN; CAFFEINE: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailym... (accessed August 28, 2018).
- "acetaminophen". https://pubchem.ncbi.nlm.nih.gov/co... (accessed August 28, 2018).
Frequently asked Questions
Can i drive or operate heavy machine after consuming Acetaminophen?Depending on the reaction of the Acetaminophen after taken, if you are feeling dizziness, drowsiness or any weakness as a reaction on your body, Then consider Acetaminophen not safe to drive or operate heavy machine after consumption. Meaning that, do not drive or operate heavy duty machines after taking the capsule if the capsule has a strange reaction on your body like dizziness, drowsiness. As prescribed by a pharmacist, it is dangerous to take alcohol while taking medicines as it exposed patients to drowsiness and health risk. Please take note of such effect most especially when taking Primosa capsule. It's advisable to consult your doctor on time for a proper recommendation and medical consultations.
Is Acetaminophen addictive or habit forming?Medicines are not designed with the mind of creating an addiction or abuse on the health of the users. Addictive Medicine is categorically called Controlled substances by the government. For instance, Schedule H or X in India and schedule II-V in the US are controlled substances.
Please consult the medicine instruction manual on how to use and ensure it is not a controlled substance.In conclusion, self medication is a killer to your health. Consult your doctor for a proper prescription, recommendation, and guidiance.
Review
sdrugs.com conducted a study on Acetaminophen, and the result of the survey is set out below. It is noteworthy that the product of the survey is based on the perception and impressions of the visitors of the website as well as the views of Acetaminophen consumers. We, as a result of this, advice that you do not base your therapeutic or medical decisions on this result, but rather consult your certified medical experts for their recommendations.Visitor reports
Two visitors reported useful
How is the drug Acetaminophen useful in reducing or relieving the symptoms? How useful is it?According to the survey conducted by the website sdrugs.com, there are variable results and below are the percentages of the users that say the medicine is useful to them and that say it is not helping them much. It is not ideal to continue taking the medication if you feel it is not helping you much. Contact your healthcare provider to check if there is a need to change the medicine or if there is a need to re-evaluate your condition. The usefulness of the medicine may vary from patient to patient, depending on the other diseases he is suffering from and slightly depends on the brand name.
| Visitors | % | ||
|---|---|---|---|
| Useful | 2 | 100.0% | |
One visitor reported side effects
Did you get side effects while taking the Acetaminophen drug, or were there no side effects?According to the survey conducted by website sdrugs.com users, the below-mentioned percentages indicate the number of people experiencing the side effects and the number of people not experiencing the side effects when taking Acetaminophen medicine. Every drug produces minimal side effects, and they are negligible most times, when compared to the desired effect [use] of the medicine. Side effects depend on the dose you are taking, any drug interactions that happen when you are on other medications, if the patient is sensitive, and other associated conditions. If you cannot tolerate the side effects, consult your doctor immediately, so he can either adjust the dose or change the medication.
| Visitors | % | ||
|---|---|---|---|
| It has side effects | 1 | 100.0% | |
Visitor reported price estimates
No survey data has been collected yetTwo visitors reported frequency of use
How often in a day do you take the medicine?Are you taking the Acetaminophen drug as prescribed by the doctor?
Few medications can be taken Twice in a day more than prescribed when the doctor's advice mentions the medicine can be taken according to frequency or severity of symptoms. Most times, be very careful and clear about the number of times you are taking the medication. The report of sdrugs.com website users about the frequency of taking the drug Acetaminophen is mentioned below.
| Visitors | % | ||
|---|---|---|---|
| Twice in a day | 1 | 50.0% | |
| 4 times in a day | 1 | 50.0% | |
Four visitors reported doses
What is the dose of Acetaminophen drug you are taking?According to the survey conducted among sdrugs.com website users, the maximum number of people are using the following dose 201-500mg. Few medications come in only one or two doses. Few are specific for adult dose and child dose. The dose of the medicine given to the patient depends on the severity of the symptom/disease. There can be dose adjustments made by the doctor, based on the progression of the disease. Follow-up is important.
| Visitors | % | ||
|---|---|---|---|
| 201-500mg | 2 | 50.0% | |
| 11-50mg | 1 | 25.0% | |
| 101-200mg | 1 | 25.0% | |
Visitor reported time for results
No survey data has been collected yetThree visitors reported administration
The drugs are administered in various routes, like oral or injection form. They are administered before food or after food. How are you taking Acetaminophen drug, before food or after food?Click here to find out how other users of our website are taking it. For any doubts or queries on how and when the medicine is administered, contact your health care provider immediately.
| Visitors | % | ||
|---|---|---|---|
| Empty stomach | 2 | 66.7% | |
| With a meal | 1 | 33.3% | |
Eight visitors reported age
| Visitors | % | ||
|---|---|---|---|
| > 60 | 4 | 50.0% | |
| 6-15 | 2 | 25.0% | |
| 46-60 | 1 | 12.5% | |
| < 1 | 1 | 12.5% | |
Visitor reviews
There are no reviews yet. Be the first to write one! |
The information was verified by Dr. Rachana Salvi, MD Pharmacology