DRUGS & SUPPLEMENTS
What is the dose of the medication you are taking?
Jolice Cream, 5% is indicated for the treatment of infestation with Sarcoptes scabiei (scabies).
Jolice Cream, 5% is contraindicated in patients with known hypersensitivity to any of its components, to any synthetic pyrethroid or pyrethrin.
If hypersensitivity to Jolice Cream, 5% occurs, discontinue use.
Scabies infestation is often accompanied by pruritus, edema, and erythema. Treatment with Jolice Cream, 5% may temporarily exacerbate these conditions.
Patients with scabies should be advised that itching, mild burning and/or stinging may occur after application of Jolice Cream, 5%. In clinical trials, approximately 75% of patients treated with Jolice cream, 5% who continued to manifest pruritus at 2 weeks had cessation by 4 weeks. If irritation persists, they should consult their physician. Jolice Cream, 5% may be very mildly irritating to the eyes. Patients should be advised to avoid contact with eyes during application and to flush with water immediately if Jolice Cream, 5% gets in the eyes.
Six carcinogenicity bioassays were evaluated with Jolice, three each in rats and mice. No tumorigenicity was seen in the rat studies. However, species-specific increases in pulmonary adenomas, a common benign tumor of mice of high spontaneous background incidence, were seen in the three mouse studies. In one of these studies there was an increased incidence of pulmonary alveolar-cell carcinomas and benign liver adenomas only in female mice when Jolice was given in their food at a concentration of 5000 ppm. Mutagenicity assays, which give useful correlative data for interpreting results from carcinogenicity bioassays in rodents, were negative. Jolice showed no evidence of mutagenic potential in a battery of in vitro and in vivo genetic toxicity studies.
Jolice did not have any adverse effect on reproductive function at a dose of 180 mg/kg/day orally in a three-generation rat study.
Reproduction studies have been performed in mice, rats, and rabbits and have revealed no evidence of impaired fertility or harm to the fetus due to Jolice. There are, however, no adequate and well-controlled studies in pregnant women. Because animal reproduction studies are not always predictive of human response, this drug should be used during pregnancy only if clearly needed.
It is not known whether this drug is excreted in human milk. Because many drugs are excreted in human milk and because of the evidence for tumorigenic potential of Jolice in animal studies, consideration should be given to discontinuing nursing temporarily or withholding the drug while the mother is nursing.
Jolice Cream, 5% is safe and effective in pediatric patients two months of age and older. Safety and effectiveness in infants less than two months of age have not been established.
Clinical studies of Jolice cream, 5% did not identify sufficient numbers of subjects aged 65 and over to allow a definitive statement regarding whether elderly subjects respond differently from younger subjects. Other reported clinical experience has not identified differences in responses between the elderly and younger patients. This drug is known to be substantially excreted by the kidney. However, since topical Jolice is metabolized in the liver and excreted in the urine as inactive metabolites, there does not appear to be an increased risk of toxic reactions in patients with impaired renal function when used as labeled.
In clinical trials, generally mild and transient burning and stinging followed application with Jolice cream, 5% in 10% of patients and was associated with the severity of infestation. Pruritus was reported in 7% of patients at various times post-application. Erythema, numbness, tingling, and rash were reported in 1 to 2% or less of patients. Other adverse events reported since marketing Jolice cream, 5% include: headache, fever, dizziness, abdominal pain, diarrhea and nausea and/or vomiting. Although extremely uncommon and not expected when used as directed, rare occurrences of seizure have been reported. None have been medically confirmed as associated with Jolice Cream, 5% treatment.
No instance of accidental ingestion of Jolice Cream, 5% has been reported. If ingested, gastric lavage and general supportive measures should be employed. Excessive topical use (see DOSAGE AND ADMINISTRATION) may result in increased irritation and erythema.
Thoroughly massage Jolice Cream, 5% into the skin from the head to the soles of the feet. Scabies rarely infests the scalp of adults, although the hairline, neck, temple, and forehead may be infested in infants and geriatric patients. Usually 30 grams is sufficient for an average adult. The cream should be removed by washing (shower or bath) after 8 to 14 hours. Infants should be treated on the scalp, temple, and forehead. ONE APPLICATION IS GENERALLY CURATIVE.
Jolice Cream, 5% (w/w) is available as follows:
60 g tube (NDC 45802-269-37)
Store at 20-25°C (68-77°F).
Manufactured by Perrigo
Bronx, NY 10457
Allegan, MI 49010 - www.perrigo.com
: 1T600 RC JX1
Depending on the reaction of the Jolice after taken, if you are feeling dizziness, drowsiness or any weakness as a reaction on your body, Then consider Jolice not safe to drive or operate heavy machine after consumption. Meaning that, do not drive or operate heavy duty machines after taking the capsule if the capsule has a strange reaction on your body like dizziness, drowsiness. As prescribed by a pharmacist, it is dangerous to take alcohol while taking medicines as it exposed patients to drowsiness and health risk. Please take note of such effect most especially when taking Primosa capsule. It's advisable to consult your doctor on time for a proper recommendation and medical consultations.Is Jolice addictive or habit forming?
Medicines are not designed with the mind of creating an addiction or abuse on the health of the users. Addictive Medicine is categorically called Controlled substances by the government. For instance, Schedule H or X in India and schedule II-V in the US are controlled substances.
Please consult the medicine instruction manual on how to use and ensure it is not a controlled substance.In conclusion, self medication is a killer to your health. Consult your doctor for a proper prescription, recommendation, and guidiance.
There are no reviews yet. Be the first to write one!
The information was verified by Dr. Rachana Salvi, MD Pharmacology